{"id":142734,"date":"2022-01-04T09:38:46","date_gmt":"2022-01-04T09:38:46","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e5%a5%b3%e6%80%a7%e3%81%ae%e5%81%a5%e5%ba%b7%e3%82%92%e5%89%8d%e9%80%b2%e3%81%95%e3%81%9b%e3%82%8b%ef%bc%9ap16-ki-67%e4%ba%8c%e9%87%8d%e6%9f%93%e8%89%b2%e6%8a%80%e8%a1%93%e3%81%af%e5%ad%90%e5%ae%ae\/"},"modified":"2026-01-19T13:11:16","modified_gmt":"2026-01-19T13:11:16","slug":"advancing-womens-health-p16-ki-67-dual-staining-technology-improves-cervical-cancer-diagnostics","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ja\/disease-area\/womens-health\/advancing-womens-health-p16-ki-67-dual-staining-technology-improves-cervical-cancer-diagnostics\/","title":{"rendered":"\u5973\u6027\u306e\u5065\u5eb7\u3092\u524d\u9032\u3055\u305b\u308b\uff1ap16\/Ki-67\u4e8c\u91cd\u67d3\u8272\u6280\u8853\u306f\u5b50\u5bae\u9838\u304c\u3093\u8a3a\u65ad\u3092\u6539\u5584\u3057\u307e\u3059"},"content":{"rendered":"<p class=\"text-align-justify\"><strong><em>\u5b50\u5bae\u9838\u304c\u3093\u304c\u4e16\u754c\u4e2d\u306e\u5973\u6027\u306e\u751f\u6d3b\u306b\u3069\u306e\u3088\u3046\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u308b\u306e\u304b\u3001\u305d\u3057\u3066\u3053\u306e\u75c5\u6c17\u3092\u4e16\u754c\u7684\u306b\u6392\u9664\u3059\u308b\u305f\u3081\u306b\u7d44\u7e54\u304c\u9032\u3081\u3066\u3044\u308b\u53d6\u308a\u7d44\u307f\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u306f\u3001<a href=\"https:\/\/conqueringcancercampaign.com\/\" target=\"_blank\" rel=\"noopener\">Conquering Cancer campaign<\/a>\uff08\u304c\u3093\u514b\u670d\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\uff09\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\u306b\u95a2\u9023\u3059\u308b\u52d5\u753b\u306f<a href=\"https:\/\/conqueringcancercampaign.com\/conquering-cancer-videos\/\" target=\"_blank\" rel=\"noopener\">\u3053\u3061\u3089<\/a>\u3002\u00a0<\/em><\/strong><\/p>\n<p class=\"text-align-justify\"><em>\u3053\u306e\u8a18\u4e8b\u306f\u3001\u5973\u6027\u306e\u5065\u5eb7\u9818\u57df\u306b\u304a\u3051\u308b\u8a3a\u65ad\u3092\u30c6\u30fc\u30de\u3068\u3057\u305f\u65b0\u30b7\u30ea\u30fc\u30ba\u306e\u4e00\u3064\u3067\u3059\u3002\u5e74\u9593\u3092\u901a\u3057\u3066\u3001\u3088\u308a\u591a\u304f\u306e\u30b9\u30c8\u30fc\u30ea\u30fc\u3084\u95a2\u9023\u30b3\u30f3\u30c6\u30f3\u30c4\u3092\u8ffd\u52a0\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u00a0<\/em><\/p>\n<p 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!important; line-height: 36px !important; letter-spacing: 0px !important;\">\u30c8\u30ea\u30a2\u30fc\u30b8\u306b\u304a\u3051\u308bp16\/Ki-67\u4e8c\u91cd\u67d3\u8272\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u4fa1\u5024<\/h3>\n<p class=\"text-align-justify\">\u8fd1\u5e74\u3001\u4e00\u6b21HPV\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306f\u591a\u304f\u306e\u56fd\u3067\u6539\u5584\u3057\u3066\u304a\u308a\u3001\u73fe\u5728Pap\u7d30\u80de\u8a3a\u304a\u3088\u3073HPV DNA\u691c\u67fb\u306b\u3088\u308b\u62e1\u5f35\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u63d0\u4f9b\u3057\u3066\u3044\u308b\u3002HPV\u611f\u67d3\u304c\u5fc5\u305a\u3057\u3082\u5b50\u5bae\u9838\u304c\u3093\u306b\u9032\u884c\u3059\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u305f\u3081\u3001\u4e00\u6b21\u306eHPV\u691c\u67fb\u3067\u967d\u6027\u3068\u306a\u3063\u305f\u5f8c\u3082\u3001\u5973\u6027\u306f\u81ea\u5206\u306e\u5b50\u5bae\u9838\u304c\u3093\u30ea\u30b9\u30af\u306e\u7a0b\u5ea6\u3092\u5224\u5b9a\u3059\u308b\u305f\u3081\u306e\u30c8\u30ea\u30a2\u30fc\u30b8\u691c\u67fb\u3092\u53d7\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002 \u3059\u3079\u3066\u306e\u967d\u6027\u75c7\u4f8b\u306b\u5bfe\u3057\u3066\u30b3\u30eb\u30dd\u30b9\u30b3\u30d4\u30fc\u3068\u3044\u3046\u4fb5\u8972\u7684\u306a\u691c\u67fb\u3092\u884c\u3046\u306e\u306f\u975e\u73fe\u5b9f\u7684\u3067\u3059\u3002\u30b3\u30eb\u30dd\u30b9\u30b3\u30d4\u30fc\u306f\u8cbb\u7528\u304c\u304b\u304b\u308b\u3046\u3048\u3001HPV\u611f\u67d3\u306e\u5927\u90e8\u5206\u304c\u4e00\u904e\u6027\u3067\u81ea\u7136\u6d88\u9000\u3059\u308b\u3053\u3068\u3092\u8e0f\u307e\u3048\u308b\u3068\u3001\u60a3\u8005\u306b\u4e0d\u8981\u306a\u30b9\u30c8\u30ec\u30b9\u3092\u4e0e\u3048\u308b\u51e6\u7f6e\u3060\u304b\u3089\u3067\u3059\u3002<\/p>\n<p 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Triage\uff08IMPACT\uff09\u8a66\u9a13[2]\u3067\u306f\u3001\u7c73\u56fd\u306b\u304a\u3044\u306625\u301c65\u6b73\u306e\u9069\u683c\u5973\u602735,000\u4eba\u4ee5\u4e0a\u3092\u5bfe\u8c61\u306b1\u5e74\u9593\u8ffd\u8de1\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u8a66\u9a13\u3067\u306f\u3001p16\u304a\u3088\u3073Ki-67\u306e\u4e8c\u91cd\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u67d3\u8272\u306e\u4f7f\u7528\u3092\u3001(a)Pap\u7d30\u80de\u8a3a\u5358\u72ec\u304a\u3088\u3073(b)HPV16\/18\u907a\u4f1d\u5b50\u578b\u5224\u5b9a\u3068\u306e\u540c\u6642\u691c\u67fb\u3068\u6bd4\u8f03\u3057\u3066\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u4e3b\u306a\u6240\u898b\u3092\u4ee5\u4e0b\u306b\u793a\u3057\u307e\u3059\u3002<\/p>\n<ul>\n<li class=\"text-align-justify\"><strong>\u4e8c\u91cd\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u67d3\u8272\u306f\u3001\u5b50\u5bae\u9838\u90e8\u75be\u60a3\u306e\u691c\u51fa\u306b\u304a\u3044\u3066\u3088\u308a\u52b9\u7387\u7684\u3067\u3059\u3002<\/strong> CIN2\u306e\u75c5\u5909\u30b9\u30c6\u30fc\u30b8\u3067\u306f\u3001Pap\u7d30\u80de\u8a3a\u5358\u72ec\u306e\u691c\u51fa\u7387\u306f65.9\uff05\u3067\u3042\u308a\u3001HPV16\/18\u907a\u4f1d\u5b50\u578b\u5224\u5b9a\u3068\u306e\u540c\u6642\u691c\u67fb\u3067\u306f76.4\uff05\u3067\u3057\u305f\u3002\u4e8c\u91cd\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u67d3\u8272\u306e\u691c\u51fa\u7387\u306f86.5\uff05\u3067\u3057\u305f\u3002\u3053\u306e\u50be\u5411\u306f\u3001CIN3\u6bb5\u968e\u306e\u75be\u60a3\u3092\u691c\u51fa\u3059\u308b\u5834\u5408\u306b\u3082\u5f53\u3066\u306f\u307e\u308a\u307e\u3059\u3002\u30b3\u30eb\u30dd\u30b9\u30b3\u30d4\u30fc\u306b\u30a8\u30b9\u30ab\u30ec\u30fc\u30b7\u30e7\u30f3\u3055\u308c\u305f\u60a3\u8005\u306e\u3046\u3061\u3001Pap\u7d30\u80de\u8a3a\u3067\u30c8\u30ea\u30a2\u30fc\u30b8\u3055\u308c\u305f\u60a3\u8005\u3088\u308a\u3082\u3001\u4e8c\u91cd\u67d3\u8272\u3067\u30c8\u30ea\u30a2\u30fc\u30b8\u3055\u308c\u305f\u5973\u6027\u306e\u307b\u3046\u304c\u75be\u60a3\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u3088\u308a\u591a\u304f\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/li>\n<li 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class=\"text-align-justify\"><strong>\u4e8c\u91cd\u67d3\u8272\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306f\u3001Pap\u7d30\u80de\u8a3a\u3088\u308a\u3082\u512a\u308c\u305f\u30ea\u30b9\u30af\u5c64\u5225\u5316\u80fd\u3092\u793a\u3057\u307e\u3059\u3002<\/strong> Pap\u7d30\u80de\u8a3a\u3082\u30c8\u30ea\u30a2\u30fc\u30b8\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e8c\u91cd\u67d3\u8272\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306f\u3001\u30ea\u30b9\u30af\u5c64\u5225\u5316\u306b\u304a\u3044\u3066\u7d30\u80de\u8a3a\u30d9\u30fc\u30b9\u306e\u65b9\u6cd5\u3088\u308a\u3082\u512a\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u6709\u610f\u306a\u9ad8\u30ea\u30b9\u30af\u7fa4\u3067\u306f\u3001\u4e8c\u91cd\u67d3\u8272\u306f19.6\uff05\u306e\u30ea\u30b9\u30af\u691c\u51fa\u306b\u5bfe\u3057\u3001Pap\u7d30\u80de\u8a3a\u306f17.8\uff05\u306e\u691c\u51fa\u7387\u3067\u3057\u305f\u3002\u4f4e\u30ea\u30b9\u30af\u7fa4\u3067\u306f\u3001\u4e8c\u91cd\u67d3\u8272\u306f3.6\uff05\u301c7.4\uff05\u3067Pap\u7d30\u80de\u8a3a\u3092\u4e0a\u56de\u308a\u307e\u3057\u305f\u3002<\/li>\n<\/ul>\n<p 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class=\"text-align-justify\">\u3053\u306e\u6709\u76ca\u6027\u304b\u3089\u3001\u30d5\u30e9\u30f3\u30b9\u3084\u30c9\u30a4\u30c4\u306e\u3088\u3046\u306a\u56fd\u3005\u3067\u306f\u3001p16\/Ki-67\u4e8c\u91cd\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u67d3\u8272\u3092\u81e8\u5e8a\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3078\u5c0e\u5165\u3057\u3066\u304a\u308a\u3001\u4eca\u5f8c\u3055\u3089\u306b\u591a\u304f\u306e\u56fd\u3067\u81e8\u5e8a\u5b9f\u8df5\u306b\u7d44\u307f\u8fbc\u307e\u308c\u308b\u3068\u4e88\u60f3\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 24px !important; line-height: 32px !important; letter-spacing: 0px !important;\">\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2(WHO)\u306e90\uff5e70\uff5e90\u306e\u76ee\u6a19\u9054\u6210<\/h3>\n<p class=\"text-align-justify\">HPV\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u88dc\u5b8c\u3059\u308b\u4e8c\u91cd\u67d3\u8272\u6280\u8853\u306f\u91cd\u8981\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3042\u308a\u3001\u5b50\u5bae\u9838\u90e8\u75c5\u5909\u306b\u5bfe\u3059\u308b\u521d\u671f\u306e\u9632\u5fa1\u624b\u6bb5\u306e\u4e00\u3064\u3068\u3057\u3066\u8a55\u4fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u767a\u304c\u3093\u6027HPV\u682a\u306b\u95a2\u9023\u3059\u308b14\u306e\u907a\u4f1d\u5b50\u578b\u306e\u3046\u3061\u3001\u307b\u3068\u3093\u3069\u306eHPV\u30ef\u30af\u30c1\u30f3\u306f\u3001\u6700\u3082\u4e00\u822c\u7684\u306a\u9ad8\u30ea\u30b9\u30af\u682a\u3067\u3042\u308bHPV16\u578b\u304a\u3088\u3073HPV18\u578b\u306e2\u7a2e\u985e\u306b\u5bfe\u3057\u3066\u975e\u5e38\u306b\u9ad8\u3044\u4e88\u9632\u52b9\u679c\u3092\u793a\u3057\u307e\u3059[3]\u3002\u305d\u308c\u3067\u3082\u3001\u4ed6\u306e\u578b\u306b\u3088\u308b\u611f\u67d3\u306f\u5f15\u304d\u7d9a\u304d\u767a\u751f\u3057\u5f97\u308b\u305f\u3081\u3001\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3068\u30c8\u30ea\u30a2\u30fc\u30b8\u306f\u4eca\u5f8c\u3082\u6b20\u304b\u3059\u3053\u3068\u306e\u3067\u304d\u306a\u3044\u3082\u306e\u3067\u3059\u3002<\/p>\n<p class=\"text-align-justify\">\u8a3a\u65ad\u306e\u4fa1\u5024\u306f\u30012020\u5e74\u306b\u767a\u8868\u3055\u308c\u305f\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\u306e\u5b50\u5bae\u9838\u304c\u3093\u64b2\u6ec5\u3092\u52a0\u901f\u3055\u305b\u308b\u305f\u3081\u306e\u30b0\u30ed\u30fc\u30d0\u30eb\u6226\u7565\u306b\u304a\u3044\u3066\u660e\u78ba\u306b\u793a\u3055\u308c\u3066\u304a\u308a\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3001\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3001\u6cbb\u7642\u3068\u3044\u30463\u3064\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u304b\u3089\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u300c90-70-90\u300d\u306e\u76ee\u6a19\u306f\u3001\u5973\u306e\u5b50\u306e90\uff05\u304c15\u6b73\u307e\u3067\u306bHPV\u306b\u5bfe\u3059\u308b\u5b8c\u5168\u306a\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u53d7\u3051\u308b\u3053\u3068\u3001\u5973\u6027\u306e70\uff05\u304c35\u6b73\u307e\u3067\u304a\u3088\u307345\u6b73\u307e\u3067\u306b\u4e00\u5ea6\u306f\u9ad8\u6027\u80fd\u691c\u67fb\u3067\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3092\u53d7\u3051\u308b\u3053\u3068\u3001\u305d\u3057\u3066\u5b50\u5bae\u9838\u90e8\u75be\u60a3\u3068\u8a3a\u65ad\u3055\u308c\u305f\u5973\u6027\u306e90\uff05\u304c\u9069\u5207\u306a\u6cbb\u7642\u3092\u53d7\u3051\u308b\u3053\u3068\u3092\u4fdd\u8a3c\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p class=\"text-align-justify\">2020\u5e74\u306b\u5b50\u5bae\u9838\u304c\u3093\u3068\u8a3a\u65ad\u3055\u308c\u305f\u5973\u6027\u306f604,000\u4eba\u3001\u6b7b\u4ea1\u8005\u6570\u306f342,000\u4eba\u3067\u3042\u308a\u3001\u5b50\u5bae\u9838\u304c\u3093\u306f\u4f9d\u7136\u3068\u3057\u3066\u5973\u6027\u306b\u304a\u3044\u30664\u756a\u76ee\u306b\u591a\u3044\u304c\u3093\u3068\u306a\u3063\u3066\u3044\u307e\u3059[6]\u3002\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306b\u95a2\u3057\u3066\u306f\u3001\u9ad8\u6027\u80fd\u306a\u691c\u67fb\u3092\u4e00\u8cab\u3057\u3066\u7528\u3044\u308b\u3053\u3068\u3068\u65e9\u671f\u767a\u898b\u3092\u5fb9\u5e95\u3059\u308b\u3053\u3068\u304c\u3001100\uff05\u4e88\u9632\u53ef\u80fd\u306a\u304c\u3093\u3092\u514b\u670d\u3059\u308b\u305f\u3081\u306e\u4e2d\u5fc3\u7684\u306a\u8981\u7d20\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n<p class=\"text-align-justify\">\u30c8\u30ea\u30a2\u30fc\u30b8\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306b\u8ffd\u52a0\u3067\u304d\u308b\u5f37\u529b\u306a\u30c4\u30fc\u30eb\u304c\u52a0\u308f\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u591a\u304f\u306e\u56fd\u304c2030\u5e74\u307e\u3067\u306b\u300c90-70-90\u300d\u76ee\u6a19\u3092\u9054\u6210\u3059\u308b\u9053\u7b4b\u306b\u4e57\u308a\u3001\u6b21\u306e\u4e16\u7d00\u306e\u3046\u3061\u306b\u5b50\u5bae\u9838\u304c\u3093\u306e\u306a\u3044\u6bb5\u968e\u3092\u5b9f\u73fe\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p class=\"text-align-justify\">\n<p><em>\u53c2\u8003\u6587\u732e<\/em>: <\/p>\n<p><a href=\"https:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfpma\/pma.cfm?id=P190024\" target=\"_blank\" rel=\"noopener\">[1]<\/a> Accessdata.fda.gov.2022. Premarket Approval (PMA). [online]\u5165\u624b\u5148\uff1a <https:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfpma\/pma.cfm?id=P190024> [2022\u5e741\u67084\u65e5]<\/p>\n<p class=\"text-align-justify\"><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.33812\" target=\"_blank\" rel=\"noopener\">[2]<\/a>\u00a0Wright, T., Stoler, M., Ranger-Moore, J., Fang, Q., Volkir, P., Safaeian, M.and Ridder, R., 2021. Clinical validation of p16\/Ki-67 dual-stained cytology triage of HPV-positive women: Results from the IMPACT trial.International Journal of Cancer, 150(3), pp.461-471.<\/p>\n<p class=\"text-align-justify\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0889854507000861?via%3Dihub\" target=\"_blank\" rel=\"noopener\">[3]<\/a> Safaeian, M., Solomon, D.and Castle, P., 2007. Cervical Cancer Prevention\u2014Cervical Screening: Science in Evolution.Obstetrics and Gynecology Clinics of North America, 34(4), pp.739-760.<\/p>\n<p class=\"text-align-justify\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/22675168\/\" target=\"_blank\" rel=\"noopener\">[4]<\/a> Wentzensen, N., Schwartz, L., Zuna, R., Smith, K., Mathews, C., Gold, M., Allen, R., Zhang, R., Dunn, S., Walker, J.and Schiffman, M., 2012. Performance of p16\/Ki-67 Immunostaining to Detect Cervical Cancer Precursors in a Colposcopy Referral Population.Clinical Cancer Research, 18(15), pp.4154-4162.<\/p>\n<p class=\"text-align-justify\"><a href=\"https:\/\/www.nature.com\/articles\/6605771.pdf\" target=\"_blank\" rel=\"noopener\">[5]<\/a> Rebolj, M.and Lynge, E., 2010. Incomplete follow-up of positive HPV tests: overview of randomized controlled trials on primary cervical screening.British Journal of Cancer, 103(3), pp.310-314.<\/p>\n<p class=\"text-align-justify\"><a href=\"https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/23-Cervix-uteri-fact-sheet.pdf\" target=\"_blank\" rel=\"noopener\">[6]<\/a> World Health Organization Fact Sheet on Cervical Cancer.\u4ee5\u4e0b\u3088\u308a\u5165\u624b\u3067\u304d\u307e\u3059\uff1a <https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/23-Cervix-uteri-fact-sheet.pdf> [2022\u5e741\u67084\u65e5\u30a2\u30af\u30bb\u30b9]<\/p>\n<p class=\"text-align-justify\">\n","protected":false},"excerpt":{"rendered":"<p>\u5b50\u5bae\u9838\u304c\u3093\u304c\u4e16\u754c\u4e2d\u306e\u5973\u6027\u306e\u751f\u6d3b\u306b\u3069\u306e\u3088\u3046\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u308b\u306e\u304b\u3001\u305d\u3057\u3066\u3053\u306e\u75c5\u6c17\u3092\u4e16\u754c\u7684\u306b\u6392\u9664\u3059\u308b\u305f\u3081\u306b\u7d44\u7e54\u304c\u9032\u3081\u3066\u3044\u308b\u53d6\u308a\u7d44\u307f\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u306f\u3001Conquering Cancer campaign\uff08\u304c\u3093\u514b\u670d\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\uff09\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\u306b\u95a2\u9023\u3059\u308b\u52d5\u753b\u306f\u3053\u3061\u3089\u3002\u00a0 \u3053\u306e\u8a18\u4e8b\u306f\u3001\u5973\u6027\u306e\u5065\u5eb7\u9818\u57df\u306b\u304a\u3051\u308b\u8a3a\u65ad\u3092\u30c6\u30fc\u30de\u3068\u3057\u305f\u65b0\u30b7\u30ea\u30fc\u30ba\u306e\u4e00\u3064\u3067\u3059\u3002\u5e74\u9593\u3092\u901a\u3057\u3066\u3001\u3088\u308a\u591a\u304f\u306e\u30b9\u30c8\u30fc\u30ea\u30fc\u3084\u95a2\u9023\u30b3\u30f3\u30c6\u30f3\u30c4\u3092\u8ffd\u52a0\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u00a0 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Premarket Approval (PMA). [online]\u5165\u624b\u5148\uff1a [2022\u5e741\u67084\u65e5] [2]\u00a0Wright, T., Stoler, M., Ranger-Moore, J., Fang, Q., Volkir, P., Safaeian, M.and Ridder, R., 2021. 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