{"id":142756,"date":"2021-03-18T05:13:28","date_gmt":"2021-03-18T05:13:28","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e3%83%91%e3%83%b3%e3%83%87%e3%83%9f%e3%83%83%e3%82%af%e4%b8%ad%e3%81%ab%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9ngs%ef%bc%88%e6%ac%a1%e4%b8%96%e4%bb%a3%e3%82%b7%e3%83%bc\/"},"modified":"2026-01-08T13:04:38","modified_gmt":"2026-01-08T13:04:38","slug":"how-ngs-tools-have-shaped-the-covid-19-pandemic-response","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ja\/operations\/sequencing\/how-ngs-tools-have-shaped-the-covid-19-pandemic-response\/","title":{"rendered":"\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u4e2d\u306b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9NGS\uff08\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b9\u89e3\u6790\uff09\u306f\u3069\u306e\u3088\u3046\u306b\u5f62\u4f5c\u3089\u308c\u305f\u304b\u3002"},"content":{"rendered":"

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SARS-CoV-2\u30b2\u30ce\u30e0\u306e\u6700\u521d\u306e\u89b3\u5bdf\u306f\u3001Fudan University\u306eShanghai Public Health Clinical Centre\u306e\u79d1\u5b66\u8005\u304b\u3089\u306e\u3082\u306e\u3067\u3057\u305f\u3002Zhang Yong-Zhen\u6559\u6388\u304c\u7387\u3044\u308b\u30c1\u30fc\u30e0\u306f\u30012019\u5e7412\u670826\u65e5\u306b\u6b66\u6f22\u306e\u60a3\u8005\u304b\u3089\u63a1\u53d6\u3057\u305f\u5206\u96e2\u682a\u3092\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u3057\u30012020\u5e741\u67085\u65e5\u306b\u30b2\u30ce\u30e0\u30a2\u30bb\u30f3\u30d6\u30ea\u3092\u5b8c\u4e86\u3057\u307e\u3057\u305f\u3002 \u3053\u306e\u30b2\u30ce\u30e0\u914d\u5217\u306f\u3001\u540c\u30c1\u30fc\u30e0\u306e\u9577\u5e74\u306e\u7814\u7a76\u30d1\u30fc\u30c8\u30ca\u30fc\u3067\u3042\u308bUniversity of Sydney\u306e\u30a6\u30a4\u30eb\u30b9\u5b66\u8005Eddie Holmes\u6559\u6388\u3068\u5171\u6709\u3055\u308c\u307e\u3057\u305f\u3002\u6559\u6388\u306f1\u670811\u65e5\u306b\u516c\u958b\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u914d\u5217\u3092\u30a2\u30c3\u30d7\u30ed\u30fc\u30c9\u3057\u3001\u4e16\u754c\u306b\u751f\u7269\u30b2\u30ce\u30e0\u3092\u7d39\u4ecb\u3057\u307e\u3057\u305f\u3002<\/p>\n

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COVID-19\u75c7\u4f8b\u306e\u4ee3\u8868\u7684\u306a\u5272\u5408\u3092\u914d\u5217\u6c7a\u5b9a\u3057\u3066\u3044\u308b\u56fd\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u304c\u3069\u306e\u3088\u3046\u306b\u9032\u5316\u3057\u3066\u3044\u308b\u304b\u3001\u3069\u306e\u5909\u7570\u304c\u6700\u3082\u61f8\u5ff5\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304b\u306b\u3064\u3044\u3066\u306e\u91cd\u8981\u306a\u60c5\u5831\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u82f1\u56fd\u3067\u6700\u521d\u306b\u691c\u51fa\u3055\u308c\u305fB.1.1.7\u30d0\u30ea\u30a2\u30f3\u30c8\u3068\u5357\u30a2\u30d5\u30ea\u30ab\u3067\u6700\u521d\u306b\u767a\u898b\u3055\u308c\u305fB.1.351\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001\u3069\u3061\u3089\u3082SARS-CoV-2\u306e\u6a19\u6e96\u7684\u306a\u9032\u5316\u901f\u5ea6\u306b\u57fa\u3065\u3044\u3066\u4e88\u60f3\u3055\u308c\u308b\u3088\u308a\u3082\u306f\u308b\u304b\u306b\u591a\u304f\u306e\u5909\u7570\u3092\u542b\u3093\u3067\u304a\u308a[7]\u3001\u79d1\u5b66\u8005\u306f\u3001\u3053\u308c\u3089\u306e\u3088\u308a\u4f1d\u67d3\u6027\u306e\u9ad8\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u9577\u671f\u611f\u67d3\u306b\u7f79\u60a3\u3057\u3066\u3044\u308b\u60a3\u8005\u306e\u4f53\u5185\u3067\u9032\u5316\u3057\u305f\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u63a8\u6e2c\u3057\u3066\u3044\u307e\u3059[8]\u3002\u7a81\u7136\u5909\u7570\u306e\u6570\u304c\u591a\u3044\u306e\u306f\u3001\u514d\u75ab\u7cfb\u306b\u3088\u308b\u8457\u3057\u304f\u7e70\u308a\u8fd4\u3055\u308c\u308b\u9078\u629e\u5727\u306b\u5fdc\u7b54\u3057\u305f\u30a6\u30a4\u30eb\u30b9\u3092\u53cd\u6620\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u4e00\u90e8\u306e\u56fd\u3067\u306f\u3001NGS\u30c4\u30fc\u30eb\u306f\u3001\u3057\u3070\u3057\u3070\u5ec3\u6c34\u306b\u57fa\u3065\u304f\u5730\u57df\u76e3\u8996\u30d7\u30ed\u30b0\u30e9\u30e0\u306b\u3082\u5c55\u958b\u3055\u308c\u3066\u3044\u307e\u3059[9]\u3002\u8fd1\u96a3\u306e\u4e0b\u6c34\u306b\u304a\u3051\u308b\u30a6\u30a4\u30eb\u30b9\u306e\u591a\u69d8\u6027\u3068\u91cf\u306b\u898b\u3089\u308c\u308b\u50be\u5411\u306f\u3001\u6570\u9031\u9593\u5f8c\u306b\u305d\u308c\u3089\u306e\u5730\u57df\u3067\u81e8\u5e8a\u7684\u306b\u898b\u3089\u308c\u308b\u3082\u306e\u3092\u4e88\u898b\u3059\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u3053\u306e\u60c5\u5831\u306f\u3001\u7279\u306b\u5730\u57df\u306e\u30ed\u30c3\u30af\u30c0\u30a6\u30f3\u306a\u3069\u306e\u7de9\u548c\u63aa\u7f6e\u306b\u95a2\u3059\u308b\u516c\u8846\u885b\u751f\u653f\u7b56\u3092\u5c0e\u304f\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n

\u3053\u308c\u3068\u306f\u5225\u306b\u3001MetaSUB[10]\u3068\u3057\u3066\u77e5\u3089\u308c\u308b\u30dc\u30e9\u30f3\u30c6\u30a3\u30a2\u4e3b\u5c0e\u306e\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3067\u306f\u3001\u4e16\u754c\u4e2d\u306e\u90fd\u5e02\u306e\u4ea4\u901a\u30b7\u30b9\u30c6\u30e0\u306a\u3069\u306e\u516c\u5171\u306e\u5834\u6240\u304b\u3089\u53ce\u96c6\u3055\u308c\u305f\u30b5\u30f3\u30d7\u30eb\u306e\u30e1\u30bf\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u3092\u4f7f\u7528\u3057\u307e\u3059\u3002\u904e\u53bb1\u5e74\u9593\u3001\u3053\u308c\u3089\u306e\u8a66\u6599\u306b\u306fSARS-CoV-2\u30b2\u30ce\u30e0\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u30c7\u30fc\u30bf\u306f\u305d\u308c\u3089\u306e\u5730\u57df\u3067\u898b\u3089\u308c\u308b\u81e8\u5e8a\u7684\u50be\u5411\u3068\u307b\u307c\u4e00\u81f4\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\u306eGlobal Infectious Hazard Preparedness\u30c7\u30a3\u30ec\u30af\u30bf\u30fc\u306eSylvie Briand\u6c0f\u306f\u3001\u6700\u8fd1\u30ea\u30ea\u30fc\u30b9\u3055\u308c\u305fSARS-CoV-2\u306e\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u306e\u4f7f\u7528\u306b\u95a2\u3059\u308b\u30ac\u30a4\u30c9\u3067\u6b21\u306e\u3088\u3046\u306b\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\u3002\u300c\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u5b9f\u65bd\u3059\u308b\u56fd\u304c\u5897\u3048\u308b\u306b\u3064\u308c\u3001\u65b0\u305f\u306b\u51fa\u73fe\u3059\u308b\u75c5\u539f\u4f53\u306e\u4e16\u754c\u3001\u306a\u3089\u3073\u306b\u3055\u307e\u3056\u307e\u306a\u6c17\u5019\u3001\u751f\u614b\u7cfb\u3001\u6587\u5316\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3001\u304a\u3088\u3073\u30d0\u30a4\u30aa\u30fc\u30e0\u306b\u304a\u3051\u308b\u30d2\u30c8\u304a\u3088\u3073\u52d5\u7269\u3068\u306e\u305d\u308c\u3089\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u3088\u308a\u3088\u304f\u7406\u89e3\u3059\u308b\u6a5f\u4f1a\u304c\u3055\u3089\u306b\u5897\u3048\u308b\u3067\u3057\u3087\u3046[11]\u3002\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u3092\u30b0\u30ed\u30fc\u30d0\u30eb\u30d8\u30eb\u30b9\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306e\u5b9f\u8df5\u306b\u8fc5\u901f\u306b\u7d44\u307f\u8fbc\u3080\u3053\u3068\u306f\u3001\u5c06\u6765\u306e\u8105\u5a01\u306b\u5bfe\u3057\u3066\u3088\u308a\u826f\u3044\u6e96\u5099\u3092\u3057\u305f\u3044\u5834\u5408\u306b\u5fc5\u8981\u3067\u3059\u3002\u300d<\/p>\n

COVID-19\u306e\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u306f\u3001\u5168\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u306e\u4fa1\u5024\u3068\u3001\u65b0\u305f\u306b\u51fa\u73fe\u3059\u308b\u75be\u60a3\u3092\u4e16\u754c\u4e2d\u306b\u62e1\u6563\u3059\u308b\u524d\u306b\u691c\u51fa\u3059\u308b\u305f\u3081\u306e\u7a4d\u6975\u7684\u306a\u611f\u67d3\u75c7\u76e3\u8996\u306e\u5fc5\u8981\u6027\u3092\u6d6e\u304d\u5f6b\u308a\u306b\u3057\u307e\u3057\u305f\u3002\u9069\u5207\u306a\u30ea\u30bd\u30fc\u30b9\u3092\u6295\u8cc7\u3057\u3001\u76e3\u8996\u30a4\u30f3\u30d5\u30e9\u3092\u69cb\u7bc9\u3057\u3066\u3001\u6b21\u306e\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u306e\u8105\u5a01\u306b\u5bfe\u3059\u308b\u6e96\u5099\u3092\u78ba\u5b9f\u306b\u6574\u3048\u308b\u3053\u3068\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n

\u30b2\u30ce\u30e0\u76e3\u8996\u3068\u75ab\u5b66\u306f\u3001\u691c\u67fb\u5ba4\u8a3a\u65ad\u304cCOVID-19\u7ba1\u7406\u3092\u3069\u306e\u3088\u3046\u306b\u30b5\u30dd\u30fc\u30c8\u3057\u3066\u3044\u308b\u304b\u3092\u793a\u3059\u4e00\u4f8b\u3067\u3059\u3002\u3053\u306e\u6a5f\u4f1a\u306e\u5168\u7bc4\u56f2\u306b\u3064\u3044\u3066\u306e\u8a73\u7d30\u306f\u3001Asia Pacific Medical Technology Association\uff08APACMed\uff09\u306b\u3088\u308b\u65b0\u3057\u3044\u30ec\u30dd\u30fc\u30c8\u3001\u300cThe Critical Role of Diagnostics in COVID-19 Management<\/a>\u300d\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002\u00a0<\/em><\/p>\n

\u53c2\u7167\uff1a<\/em><\/p>\n

[1]<\/a> GISAID\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9<\/p>\n

[2]<\/a> Sequencing COVID-19 at the Sanger Institute, The Sanger Institute Blog<\/p>\n

[3]<\/a> The Critical Role of Diagnostics in COVID-19 management, APACMed<\/p>\n

[4]<\/a> Genomic epidemiology of novel coronavirus – Asia-focused subsampling, Nextstrain<\/p>\n

[5]<\/a> “Coronavirus: India hunts for new strains as Covid wave looms”, BBC<\/p>\n

[6]<\/a> “Indonesia ramps up efforts to spot elusive COVID variants”, Nikkei Asia<\/p>\n

[7]<\/a> \u201cThe most worrying mutations in\u00a0five emerging coronavirus variants\u201d, Scientific American<\/p>\n

[8]<\/a> \u201cAn accelerated cauldron of evolution\u2019: Covid-19 patients with cancer, HIV, may play a role in emergence of variants\u201d, The Washington Post<\/p>\n

[9]<\/a> “Tracking COVID-19 with wasterwater”, Nature Biotechnology<\/p>\n

[10]<\/a> MetaSUB\u30b3\u30f3\u30bd\u30fc\u30b7\u30a2\u30e0<\/p>\n

[11]<\/a> World Health Organization Guidelines on Genomic Sequencing of SARS-CoV-2<\/p>\n

\n","protected":false},"excerpt":{"rendered":"

\u306f\u3058\u3081\u306b \u2013 \u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b9\u89e3\u6790COVID19 \u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9NGS\u306e\u5229\u7528\u53ef\u80fd\u6027\u3068\u624b\u9803\u306a\u4fa1\u683c\u306e \u304a\u304b\u3052\u3067\u3001\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b9\u89e3\u6790\uff08NGS\uff09\u306f\u3001COVID-19\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u3078\u306e\u79d1\u5b66\u754c\u306e\u5bfe\u5fdc\u306b\u4e0d\u53ef\u6b20\u306a\u8981\u7d20\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u30b2\u30ce\u30e0\u914d\u5217\u306b\u57fa\u3065\u304f\u8a3a\u65ad\u691c\u67fb\u53ca\u3073\u30ef\u30af\u30c1\u30f3\u306e\u524d\u4f8b\u306e\u306a\u3044\u75c5\u539f\u4f53\u76e3\u8996\u53ca\u3073\u8fc5\u901f\u306a\u958b\u767a\u3092\u53ef\u80fd\u306b\u3057\u307e\u3057\u305f\u3002 SARS-CoV-2\u30b2\u30ce\u30e0\u306e\u6700\u521d\u306e\u89b3\u5bdf\u306f\u3001Fudan University\u306eShanghai Public Health Clinical Centre\u306e\u79d1\u5b66\u8005\u304b\u3089\u306e\u3082\u306e\u3067\u3057\u305f\u3002Zhang Yong-Zhen\u6559\u6388\u304c\u7387\u3044\u308b\u30c1\u30fc\u30e0\u306f\u30012019\u5e7412\u670826\u65e5\u306b\u6b66\u6f22\u306e\u60a3\u8005\u304b\u3089\u63a1\u53d6\u3057\u305f\u5206\u96e2\u682a\u3092\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u3057\u30012020\u5e741\u67085\u65e5\u306b\u30b2\u30ce\u30e0\u30a2\u30bb\u30f3\u30d6\u30ea\u3092\u5b8c\u4e86\u3057\u307e\u3057\u305f\u3002 \u3053\u306e\u30b2\u30ce\u30e0\u914d\u5217\u306f\u3001\u540c\u30c1\u30fc\u30e0\u306e\u9577\u5e74\u306e\u7814\u7a76\u30d1\u30fc\u30c8\u30ca\u30fc\u3067\u3042\u308bUniversity of Sydney\u306e\u30a6\u30a4\u30eb\u30b9\u5b66\u8005Eddie Holmes\u6559\u6388\u3068\u5171\u6709\u3055\u308c\u307e\u3057\u305f\u3002\u6559\u6388\u306f1\u670811\u65e5\u306b\u516c\u958b\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u914d\u5217\u3092\u30a2\u30c3\u30d7\u30ed\u30fc\u30c9\u3057\u3001\u4e16\u754c\u306b\u751f\u7269\u30b2\u30ce\u30e0\u3092\u7d39\u4ecb\u3057\u307e\u3057\u305f\u3002 \u305d\u306e\u914d\u5217\u30c7\u30fc\u30bf\u306f\u30ef\u30af\u30c1\u30f3\u958b\u767a\u52aa\u529b\u306e\u305f\u3081\u306b\u76f4\u3061\u306b\u5c55\u958b\u3055\u308c\u3001\u81e8\u5e8a\u8a66\u9a13\u4ee5\u5916\u3067\u4f7f\u7528\u3055\u308c\u305f\u6700\u521d\u306e2\u3064\u306emRNA\u30ef\u30af\u30c1\u30f3\u306e\u57fa\u790e\u3092\u7bc9\u304d\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u4eca\u65e5\u4f7f\u7528\u3055\u308c\u308b\u591a\u304f\u306eSARS-CoV-2\u8a3a\u65ad\u8a66\u9a13\u306e\u57fa\u790e\u3068\u3057\u3066\u3082\u6a5f\u80fd\u3057\u3066\u3044\u307e\u3059\u3002 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Center\u306f\u6700\u8fd1\u6b21\u306e\u3088\u3046\u306a\u30c4\u30a4\u30fc\u30c8\u3092\u3057\u307e\u3057\u305f\u3002\u300c\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u9818\u57df\u306b\u8907\u6570\u306e\u61f8\u5ff5\u3055\u308c\u308b\u5909\u7570\u3092\u6709\u3059\u308bSARS-CoV-2\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001PGC\u306eDNA\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u30b3\u30a2\u65bd\u8a2d\u3067\u306e\u5168\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u306b\u3088\u3063\u3066\u6700\u521d\u306b\u691c\u51fa\u3055\u308c\u3001PH\u3067\u30b2\u30ce\u30e0\u7684\u306b\u7279\u5fb4\u4ed8\u3051\u3089\u308c\u30012021\u5e743\u670810\u65e5\u306bLineage P.3\u3068\u3057\u3066\u6b63\u5f0f\u306b\u6307\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002\u300d COVID-19\u75c7\u4f8b\u306e\u4ee3\u8868\u7684\u306a\u5272\u5408\u3092\u914d\u5217\u6c7a\u5b9a\u3057\u3066\u3044\u308b\u56fd\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u304c\u3069\u306e\u3088\u3046\u306b\u9032\u5316\u3057\u3066\u3044\u308b\u304b\u3001\u3069\u306e\u5909\u7570\u304c\u6700\u3082\u61f8\u5ff5\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304b\u306b\u3064\u3044\u3066\u306e\u91cd\u8981\u306a\u60c5\u5831\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u82f1\u56fd\u3067\u6700\u521d\u306b\u691c\u51fa\u3055\u308c\u305fB.1.1.7\u30d0\u30ea\u30a2\u30f3\u30c8\u3068\u5357\u30a2\u30d5\u30ea\u30ab\u3067\u6700\u521d\u306b\u767a\u898b\u3055\u308c\u305fB.1.351\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001\u3069\u3061\u3089\u3082SARS-CoV-2\u306e\u6a19\u6e96\u7684\u306a\u9032\u5316\u901f\u5ea6\u306b\u57fa\u3065\u3044\u3066\u4e88\u60f3\u3055\u308c\u308b\u3088\u308a\u3082\u306f\u308b\u304b\u306b\u591a\u304f\u306e\u5909\u7570\u3092\u542b\u3093\u3067\u304a\u308a[7]\u3001\u79d1\u5b66\u8005\u306f\u3001\u3053\u308c\u3089\u306e\u3088\u308a\u4f1d\u67d3\u6027\u306e\u9ad8\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u9577\u671f\u611f\u67d3\u306b\u7f79\u60a3\u3057\u3066\u3044\u308b\u60a3\u8005\u306e\u4f53\u5185\u3067\u9032\u5316\u3057\u305f\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u63a8\u6e2c\u3057\u3066\u3044\u307e\u3059[8]\u3002\u7a81\u7136\u5909\u7570\u306e\u6570\u304c\u591a\u3044\u306e\u306f\u3001\u514d\u75ab\u7cfb\u306b\u3088\u308b\u8457\u3057\u304f\u7e70\u308a\u8fd4\u3055\u308c\u308b\u9078\u629e\u5727\u306b\u5fdc\u7b54\u3057\u305f\u30a6\u30a4\u30eb\u30b9\u3092\u53cd\u6620\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 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\u3053\u308c\u3068\u306f\u5225\u306b\u3001MetaSUB[10]\u3068\u3057\u3066\u77e5\u3089\u308c\u308b\u30dc\u30e9\u30f3\u30c6\u30a3\u30a2\u4e3b\u5c0e\u306e\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3067\u306f\u3001\u4e16\u754c\u4e2d\u306e\u90fd\u5e02\u306e\u4ea4\u901a\u30b7\u30b9\u30c6\u30e0\u306a\u3069\u306e\u516c\u5171\u306e\u5834\u6240\u304b\u3089\u53ce\u96c6\u3055\u308c\u305f\u30b5\u30f3\u30d7\u30eb\u306e\u30e1\u30bf\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u3092\u4f7f\u7528\u3057\u307e\u3059\u3002\u904e\u53bb1\u5e74\u9593\u3001\u3053\u308c\u3089\u306e\u8a66\u6599\u306b\u306fSARS-CoV-2\u30b2\u30ce\u30e0\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u30c7\u30fc\u30bf\u306f\u305d\u308c\u3089\u306e\u5730\u57df\u3067\u898b\u3089\u308c\u308b\u81e8\u5e8a\u7684\u50be\u5411\u3068\u307b\u307c\u4e00\u81f4\u3057\u3066\u3044\u307e\u3059\u3002 \u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\u306eGlobal Infectious Hazard Preparedness\u30c7\u30a3\u30ec\u30af\u30bf\u30fc\u306eSylvie Briand\u6c0f\u306f\u3001\u6700\u8fd1\u30ea\u30ea\u30fc\u30b9\u3055\u308c\u305fSARS-CoV-2\u306e\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u306e\u4f7f\u7528\u306b\u95a2\u3059\u308b\u30ac\u30a4\u30c9\u3067\u6b21\u306e\u3088\u3046\u306b\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\u3002\u300c\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u5b9f\u65bd\u3059\u308b\u56fd\u304c\u5897\u3048\u308b\u306b\u3064\u308c\u3001\u65b0\u305f\u306b\u51fa\u73fe\u3059\u308b\u75c5\u539f\u4f53\u306e\u4e16\u754c\u3001\u306a\u3089\u3073\u306b\u3055\u307e\u3056\u307e\u306a\u6c17\u5019\u3001\u751f\u614b\u7cfb\u3001\u6587\u5316\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3001\u304a\u3088\u3073\u30d0\u30a4\u30aa\u30fc\u30e0\u306b\u304a\u3051\u308b\u30d2\u30c8\u304a\u3088\u3073\u52d5\u7269\u3068\u306e\u305d\u308c\u3089\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u3088\u308a\u3088\u304f\u7406\u89e3\u3059\u308b\u6a5f\u4f1a\u304c\u3055\u3089\u306b\u5897\u3048\u308b\u3067\u3057\u3087\u3046[11]\u3002\u30b2\u30ce\u30e0\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u3092\u30b0\u30ed\u30fc\u30d0\u30eb\u30d8\u30eb\u30b9\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306e\u5b9f\u8df5\u306b\u8fc5\u901f\u306b\u7d44\u307f\u8fbc\u3080\u3053\u3068\u306f\u3001\u5c06\u6765\u306e\u8105\u5a01\u306b\u5bfe\u3057\u3066\u3088\u308a\u826f\u3044\u6e96\u5099\u3092\u3057\u305f\u3044\u5834\u5408\u306b\u5fc5\u8981\u3067\u3059\u3002\u300d 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\u30b2\u30ce\u30e0\u76e3\u8996\u3068\u75ab\u5b66\u306f\u3001\u691c\u67fb\u5ba4\u8a3a\u65ad\u304cCOVID-19\u7ba1\u7406\u3092\u3069\u306e\u3088\u3046\u306b\u30b5\u30dd\u30fc\u30c8\u3057\u3066\u3044\u308b\u304b\u3092\u793a\u3059\u4e00\u4f8b\u3067\u3059\u3002\u3053\u306e\u6a5f\u4f1a\u306e\u5168\u7bc4\u56f2\u306b\u3064\u3044\u3066\u306e\u8a73\u7d30\u306f\u3001Asia Pacific Medical Technology Association\uff08APACMed\uff09\u306b\u3088\u308b\u65b0\u3057\u3044\u30ec\u30dd\u30fc\u30c8\u3001\u300cThe Critical Role of Diagnostics in COVID-19 Management\u300d\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002\u00a0 \u53c2\u7167\uff1a [1] GISAID\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9 [2] Sequencing COVID-19 at the Sanger Institute, 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