{"id":142789,"date":"2023-01-10T07:13:35","date_gmt":"2023-01-10T07:13:35","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e7%99%8c%e3%81%8a%e3%82%88%e3%81%b3%e7%82%8e%e7%97%87%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e8%a1%80%e6%a0%93%e7%97%87%ef%bc%9ang-heng-joo%e6%95%99%e6%8e%88%e3%81%ae%e7%9f%a5%e8%a6%8b\/"},"modified":"2026-01-09T05:06:43","modified_gmt":"2026-01-09T05:06:43","slug":"thrombosis-in-cancer-and-inflammation-insights-from-prof-ng-heng-joo","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ja\/disease-area\/coagulation\/thrombosis-in-cancer-and-inflammation-insights-from-prof-ng-heng-joo\/","title":{"rendered":"\u764c\u304a\u3088\u3073\u708e\u75c7\u306b\u304a\u3051\u308b\u8840\u6813\u75c7\uff1aNg Heng Joo\u6559\u6388\u306e\u77e5\u898b"},"content":{"rendered":"<p class=\"text-align-justify\">2022\u5e743\u6708\u306b\u6700\u5f8c\u306b\u958b\u50ac\u3055\u308c\u305f\u30ed\u30b7\u30e5\u30fb\u30c0\u30a4\u30a2\u30b0\u30ce\u30b9\u30c6\u30a3\u30c3\u30af\u30b9\u304c\u4e3b\u50ac\u3059\u308b\u8840\u6db2\u51dd\u56fa\u306b\u95a2\u3059\u308b\u6bce\u5e74\u306e\u79d1\u5b66\u7684\u304a\u3088\u3073\u6559\u80b2\u7684\u30a4\u30d9\u30f3\u30c8\u3067\u3042\u308b<a href=\"https:\/\/diagnostics.roche.com\/global\/en\/events\/pro-coag.html\" target=\"_blank\" rel=\"noopener\">pro-COAG<\/a>\u306b\u304a\u3044\u3066\u3001\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u7dcf\u5408\u75c5\u9662\u8840\u6db2\u5185\u79d1\u306e\u4e3b\u4efb\u517c\u30b7\u30cb\u30a2\u30b3\u30f3\u30b5\u30eb\u30bf\u30f3\u30c8\u3067\u3042\u308b Ng Heng Joo \u6559\u6388\u304c\u3001\u304c\u3093\u304a\u3088\u3073\u708e\u75c7\u306b\u304a\u3051\u308b\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\uff08VTE\uff09\u306e\u539f\u56e0\u3001\u767a\u75c7\u3001\u304a\u3088\u3073\u6cbb\u7642\u306b\u3064\u3044\u3066\u30ec\u30d3\u30e5\u30fc\u3057\u307e\u3057\u305f\u3002<\/p>\n<h2 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 28px !important; line-height: 36px !important; letter-spacing: 0px !important;\">\u304c\u3093<\/h2>\n<p class=\"text-align-justify\">\u304c\u3093\u306b\u304a\u3051\u308b\u8840\u6813\u4e8b\u8c61\u306f\u3088\u304f\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u7279\u306b\u4e0b\u80a2\u6df1\u90e8\u9759\u8108\u8840\u6813\u75c7\uff08DVT\uff09\u306b\u7531\u6765\u3059\u308b\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\uff08VTE\uff09\u306e\u983b\u5ea6\u306f\u5341\u5206\u306b\u691c\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u75c7\u4f8b\u306e 0.6\u301c7.8\uff05\u3092\u5360\u3081\u307e\u3059\u3002\u8fd1\u4f4d DVT \u3068\u52d5\u8108\u8840\u6813\u75c7\u306f\u3001\u305d\u308c\u305e\u308c\u80ba\u585e\u6813\u75c7\uff08PE\uff09\u304a\u3088\u3073\u8133\u5352\u4e2d\u3092\u5f15\u304d\u8d77\u3053\u3059\u50be\u5411\u304c\u3042\u308b\u305f\u3081\u3001\u7279\u306b\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u6700\u9069\u306a\u6cbb\u7642\u52b9\u679c\u3092\u5f97\u308b\u305f\u3081\u306b\u306f\u3001\u304c\u3093\u306b\u95a2\u9023\u3059\u308b\u8840\u6813\u6027\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u3001\u305d\u306e\u4ed6\u306e\u95a2\u9023\u30ea\u30b9\u30af\u56e0\u5b50\u3092\u5341\u5206\u306b\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p 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class=\"text-align-justify\">\u4e88\u6e2c\u3069\u304a\u308a\u3001\u9032\u884c\u6027\u306e\u304c\u3093\u3084\u8840\u7ba1\u304c\u8c4a\u5bcc\u306a\u81d3\u5668\u306e\u816b\u760d\u306f\u3001\u8840\u6813\u75c7\u306e\u30ea\u30b9\u30af\u304c\u6700\u3082\u9ad8\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u60a3\u8005\u306e\u5371\u967a\u56e0\u5b50\uff08\u4f8b\uff1a\u5e74\u9f62\uff09\u3001\u4e0d\u52d5\u72b6\u614b\u3001\u4f75\u5b58\u75be\u60a3\u306e\u8ca0\u62c5\u3001\u305d\u3057\u3066\u5316\u5b66\u7642\u6cd5\u85ac\u306b\u56fa\u6709\u306e\u8840\u6813\u5f62\u6210\u4fc3\u9032\u4f5c\u7528\u306b\u3088\u3063\u3066\u3001\u3055\u3089\u306b\u5f37\u8abf\u3055\u308c\u307e\u3059\u3002Khorana \u30b9\u30b3\u30a2\u306a\u3069\u306e\u6307\u6a19\u3067\u8a55\u4fa1\u3055\u308c\u308b\u3088\u3046\u306b\u3001 \u3059\u3079\u3066\u306e\u5165\u9662\u60a3\u8005\u3001\u304a\u3088\u3073 \u9ad8\u30ea\u30b9\u30af\u307e\u305f\u306f\u4e2d\u7b49\u5ea6\u30ea\u30b9\u30af\u306e\u5916\u6765\u304c\u3093\u60a3\u8005 \u3067\u306f\u3001 \u8840\u6813\u4e88\u9632\uff08\u76f4\u63a5\u7d4c\u53e3\u6297\u51dd\u56fa\u85ac\u307e\u305f\u306f\u4f4e\u5206\u5b50\u91cf\u30d8\u30d1\u30ea\u30f3\u306b\u3088\u308b\u4e88\u9632\uff09\u304c\u63a8\u5968\u3055\u308c\u307e\u3059[1]\u3002<\/p>\n<h2 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 28px !important; line-height: 36px !important; letter-spacing: 0px !important;\">\u708e\u75c7<\/h2>\n<p class=\"text-align-justify\">\u8ee2\u5e30\u306f\u985e\u4f3c\u3057\u3066\u3044\u308b\u3082\u306e\u306e\u3001\u611f\u67d3\u3084\u708e\u75c7\u6027\u523a\u6fc0\u306b\u5bfe\u3059\u308b\u514d\u75ab\u5fdc\u7b54\u306b\u8d77\u56e0\u3059\u308b\u75c5\u7406\u5b66\u7684\u8840\u6813\u75c7\u306f\u3001 \u904e\u5270\u306a\u751f\u7406\u5b66\u7684\u514d\u75ab\u8840\u6813\u75c7\uff08immunothrombosis\uff09\u306e\u4ea2\u9032 \u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u3001\u8840\u7ba1\u58c1\u4e0a\u306e\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3\u53d7\u5bb9\u4f53\u3084\u63a5\u7740\u5206\u5b50\u306e\u767a\u73fe\u4e0a\u6607\u3001 \u8840\u7ba1\u5185\u76ae\u3078\u306e\u597d\u4e2d\u7403\u306e\u63a5\u7740\u3001\u5358\u7403\u306e\u6d3b\u6027\u5316\u3084\u7d44\u7e54\u56e0\u5b50\u306e\u767a\u73fe\u3001 \u4e26\u3073\u306b\u597d\u4e2d\u7403\u304c\u8840\u6813\u306e\u57fa\u76e4\u3068\u306a\u308b\u597d\u4e2d\u7403\u7d30\u80de\u5916\u30c8\u30e9\u30c3\u30d7\uff08NETosis\uff09\u3092\u5f62\u6210\u3057\u3001 \u305d\u306e\u5f8c\u306b\u51dd\u56fa\u30ab\u30b9\u30b1\u30fc\u30c9\u304c\u6d3b\u6027\u5316\u3055\u308c\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u9032\u884c\u3057\u307e\u3059\u3002<\/p>\n<p class=\"text-align-justify\">\u611f\u67d3\u75c7\uff08\u4f8b\uff1aCOVID-19\uff09\u306e\u3088\u3046\u306b \u51dd\u56fa\u4ea2\u9032\u72b6\u614b \u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u72b6\u6cc1\u3067\u306f\u3001 \u8840\u6813\u4e88\u9632\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u304c\u3001\u708e\u75c7\u6027\u8840\u6813\u75c7\u306f\u5fc5\u305a\u3057\u3082\u6297\u51dd\u56fa\u7642\u6cd5\u306b\u53cd\u5fdc\u3059\u308b\u3068\u306f\u9650\u3089\u305a\u3001 \u6297\u708e\u75c7\u85ac\u3067\u6cbb\u7642\u3057\u305f\u65b9\u304c\u9069\u3057\u3066\u3044\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u73fe\u5728\u3082\u3001\u8b70\u8ad6\u304c\u7d9a\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n<p class=\"text-align-justify\"><em>Ng Heng Joo \u533b\u5e2b\u306f\u3001\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u7dcf\u5408\u75c5\u9662\u306e\u8840\u6db2\u5185\u79d1\u3067 \u30b7\u30cb\u30a2\u30b3\u30f3\u30b5\u30eb\u30bf\u30f3\u30c8\u517c\u90e8\u9580\u9577\u3092\u52d9\u3081\u3066\u304a\u308a\u3001 Duke-National University of Singapore\uff08NUS\uff09School of Medicine \u306e\u81e8\u5e8a\u6559\u6388\u3001 \u3055\u3089\u306b NUS \u306e Yong Loo Lin School of Medicine \u306e\u30b7\u30cb\u30a2\u8b1b\u5e2b\u3082\u52d9\u3081\u3066\u3044\u307e\u3059\u3002<\/em><\/p>\n<p class=\"text-align-justify\">\u53c2\u8003\u6587\u732e\uff1a<\/p>\n<p><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2021.669288\/full\" target=\"_blank\" rel=\"noopener\">[1]<\/a> Lee, LH, et al.Front\u00a0Cardiovasc Med, 2021;8:669288<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2022\u5e743\u6708\u306b\u6700\u5f8c\u306b\u958b\u50ac\u3055\u308c\u305f\u30ed\u30b7\u30e5\u30fb\u30c0\u30a4\u30a2\u30b0\u30ce\u30b9\u30c6\u30a3\u30c3\u30af\u30b9\u304c\u4e3b\u50ac\u3059\u308b\u8840\u6db2\u51dd\u56fa\u306b\u95a2\u3059\u308b\u6bce\u5e74\u306e\u79d1\u5b66\u7684\u304a\u3088\u3073\u6559\u80b2\u7684\u30a4\u30d9\u30f3\u30c8\u3067\u3042\u308bpro-COAG\u306b\u304a\u3044\u3066\u3001\u30b7\u30f3\u30ac\u30dd\u30fc\u30eb\u7dcf\u5408\u75c5\u9662\u8840\u6db2\u5185\u79d1\u306e\u4e3b\u4efb\u517c\u30b7\u30cb\u30a2\u30b3\u30f3\u30b5\u30eb\u30bf\u30f3\u30c8\u3067\u3042\u308b Ng Heng Joo \u6559\u6388\u304c\u3001\u304c\u3093\u304a\u3088\u3073\u708e\u75c7\u306b\u304a\u3051\u308b\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\uff08VTE\uff09\u306e\u539f\u56e0\u3001\u767a\u75c7\u3001\u304a\u3088\u3073\u6cbb\u7642\u306b\u3064\u3044\u3066\u30ec\u30d3\u30e5\u30fc\u3057\u307e\u3057\u305f\u3002 \u304c\u3093 \u304c\u3093\u306b\u304a\u3051\u308b\u8840\u6813\u4e8b\u8c61\u306f\u3088\u304f\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u7279\u306b\u4e0b\u80a2\u6df1\u90e8\u9759\u8108\u8840\u6813\u75c7\uff08DVT\uff09\u306b\u7531\u6765\u3059\u308b\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\uff08VTE\uff09\u306e\u983b\u5ea6\u306f\u5341\u5206\u306b\u691c\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u75c7\u4f8b\u306e 0.6\u301c7.8\uff05\u3092\u5360\u3081\u307e\u3059\u3002\u8fd1\u4f4d DVT 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