{"id":142825,"date":"2023-06-01T01:53:26","date_gmt":"2023-06-01T01:53:26","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e6%96%b0%e3%81%97%e3%81%84hbv%e3%83%90%e3%82%a4%e3%82%aa%e3%83%9e%e3%83%bc%e3%82%ab%e3%83%bc%e3%81%af%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e6%b8%9b%e5%b0%91%e3%81%ae%e5%8f%96%e3%82%8a%e7%b5%84\/"},"modified":"2026-01-20T09:39:13","modified_gmt":"2026-01-20T09:39:13","slug":"new-hbv-biomarkers-support-virus-reduction-efforts","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ja\/operations\/immunoassay\/new-hbv-biomarkers-support-virus-reduction-efforts\/","title":{"rendered":"\u65b0\u3057\u3044HBV\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306f\u30a6\u30a4\u30eb\u30b9\u6e1b\u5c11\u306e\u53d6\u308a\u7d44\u307f\u3092\u652f\u63f4"},"content":{"rendered":"<p 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class=\"text-align-justify\">\u30a6\u30a7\u30d3\u30ca\u30fc\u3067\u306f\u3001University of Melbourne\u306eSt Vincent\u2019s Hospital\u3067\u6d88\u5316\u5668\u5185\u79d1\u90e8\u9577\u3092\u52d9\u3081\u308bProf Alex Thompson\u3001\u304a\u3088\u3073University of Sydney\u304a\u3088\u3073\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u306eWestmead Institute for Medical Research\u306eStorr Liver Centre\u3067\u51c6\u6559\u6388\u3092\u52d9\u3081\u308bA\/Prof Mark Douglas\u306e\u767a\u8868\u3092\u7279\u96c6\u3057\u307e\u3057\u305f\u3002<\/p>\n<h2 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 28px !important; line-height: 36px !important; letter-spacing: 0px !important;\">HBV\u6e1b\u5c11\u306e\u91cd\u8981\u6027<\/h2>\n<p 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class=\"text-align-justify\">\u3053\u308c\u304c\u3001\u516c\u8846\u885b\u751f\u6a5f\u95a2\u304c\u30a6\u30a4\u30eb\u30b9\u3092\u6e1b\u5c11\u53c8\u306f\u6392\u9664\u3059\u308b\u305f\u3081\u306e\u5927\u898f\u6a21\u306a\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\u306e\u305f\u3081\u306bHBV\u3092\u6a19\u7684\u3068\u3057\u305f\u7406\u7531\u3067\u3059\u30022016\u5e74\u306b\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\u306f\u30012030\u5e74\u307e\u3067\u306bHBV\u611f\u67d3\u309290%\u6e1b\u5c11\u3055\u305b\u3001\u6b7b\u4ea1\u309265%\u6e1b\u5c11\u3055\u305b\u308b<a href=\"https:\/\/www.who.int\/news\/item\/25-06-2021-who-releases-first-ever-global-guidance-for-country-validation-of-viral-hepatitis-b-and-c-elimination\" target=\"_blank\" rel=\"noopener\">\u8a08\u753b\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u3002<\/a> 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class=\"text-align-justify\">\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u3067\u306f\u3001\u56fd\u5bb6\u6226\u7565\u306e\u76ee\u6a19\u306f\u3001\u5c0f\u5150\u4e88\u9632\u63a5\u7a2e\u306e\u666e\u53ca\u3001\u3088\u308a\u591a\u304f\u306e\u6162\u6027\u75c7\u4f8b\u3092\u767a\u898b\u3059\u308b\u305f\u3081\u306e\u8a3a\u65ad\u62e1\u5927\u3001\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u304a\u3088\u3073\u305d\u306e\u4ed6\u306e\u6cbb\u7642\u6cd5\u306e\u5229\u7528\u53ef\u80fd\u6027\u306e\u5411\u4e0a\u3067\u3059\u3002Prof Thompson\u3068Prof Douglas\u306f\u3001\u69d8\u3005\u306a\u6297\u539f\u3084\u305d\u306e\u4ed6\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3092\u691c\u67fb\u3057\u3001\u60a3\u8005\u306e\u8a3a\u65ad\u3084\u6cbb\u7642\u4e2d\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306b\u3069\u306e\u3088\u3046\u306b\u4f7f\u7528\u3067\u304d\u308b\u304b\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u3067\u3001\u539f\u56e0\u306b\u8ca2\u732e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p 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Douglas\u306f\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n<p class=\"text-align-justify\">\u65b0\u3057\u3044\u30de\u30fc\u30ab\u30fc\u3092\u958b\u767a\u3057\u7d9a\u3051\u308b\u3053\u3068\u3082\u91cd\u8981\u3067\u3059\u3002\u65b0\u305f\u306a\u30de\u30fc\u30ab\u30fc\u306f\u3001HBV\u60a3\u8005\u306e\u305f\u3081\u306e\u500b\u5225\u5316\u533b\u7642\u306e\u6642\u4ee3\u3092\u53ef\u80fd\u306b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3001Prof Thompson\u306f\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u9670\u6027\u307e\u305f\u306f\u967d\u6027\u306e\u7d50\u679c\u3092\u5358\u306b\u5831\u544a\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001ELISA\u3092\u7528\u3044\u3066\u8868\u9762\u6297\u539f\u30de\u30fc\u30ab\u30fc\u3092\u5b9a\u91cf\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u5404\u60a3\u8005\u306e\u6cbb\u7642\u3092\u958b\u59cb\u307e\u305f\u306f\u505c\u6b62\u3059\u308b\u6642\u671f\u3092\u6c7a\u5b9a\u3059\u308b\u969b\u306b\u3001\u3053\u308c\u3089\u306e\u30de\u30fc\u30ab\u30fc\u306b\u4ed8\u52a0\u7684\u306a\u4fa1\u5024\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<p 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class=\"text-align-justify\">\u300c\u8868\u9762\u6297\u539f\u30ec\u30d9\u30eb\u306f\u4eca\u3001\u4e3b\u306a\u6642\u9593\u306e\u6e96\u5099\u304c\u3067\u304d\u3066\u3044\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u300d\u3068\u3001HBV\u306e\u5168\u3066\u306e\u60a3\u8005\u306b\u304a\u3044\u3066\u3053\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u691c\u67fb\u3092\u63a8\u5968\u3059\u308bProf Thompson\u306f\u8ff0\u3079\u307e\u3057\u305f\u3002\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u307e\u305f\u3001\u81e8\u5e8a\u8a66\u9a13\u306b\u3042\u308b\u6ce8\u5c04\u53ef\u80fd\u306a\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u30aa\u30ea\u30b4\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306a\u3069\u306e\u958b\u767a\u4e2d\u306e\u65b0\u898f\u51e6\u7f6e\u306e\u9069\u5207\u306a\u9078\u629e\u306e\u305f\u3081\u306b\u5c06\u6765\u7684\u306b\u91cd\u8981\u3067\u3042\u308a\u5f97\u307e\u3059\u3002\u300cB\u578b\u809d\u708e\u306e\u6cbb\u7642\u85ac\u306e\u65b0\u3057\u3044\u6642\u4ee3\u304c\u59cb\u307e\u3063\u3066\u3044\u307e\u3059\u300d\u3068\u540c\u6c0f\u306f\u4ed8\u3051\u52a0\u3048\u307e\u3057\u305f\u3002<\/p>\n<p class=\"text-align-justify\">\u771f\u306e\u898b\u8fbc\u307f\u306e\u3042\u308b\u65b0\u305f\u306a\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306fHBV RNA\u3067\u3042\u308a\u3001\u3053\u308c\u306fHBV DNA\u3088\u308a\u3082\u8ee2\u5199\u6d3b\u6027\u306e\u3088\u308a\u6709\u7528\u306a\u30b9\u30ca\u30c3\u30d7\u30b7\u30e7\u30c3\u30c8\u3092\u63d0\u4f9b\u3057\u5f97\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001B\u578b\u809d\u708eNA\u51e6\u7f6e\u505c\u6b62\u7814\u7a76\u3067\u306f\u3001HBV RNA\u306e\u5897\u52a0\u306f\u809d\u708e\u30d5\u30ec\u30a2\u306e\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u3001HBsAg\u55aa\u5931\u306b\u8ca0\u306e\u95a2\u9023\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002Prof Thompson\u306f\u307e\u305f\u3001HBV RNA\u304c\u3001\u514d\u75ab\u4e0d\u5168\u60a3\u8005\u306b\u304a\u3051\u308bHBV\u518d\u6d3b\u6027\u5316\u3001HCC\u306e\u30ea\u30b9\u30af\u53c8\u306f\u65b0\u898f\u6cbb\u7642\u6cd5\u306b\u5bfe\u3059\u308b\u5fdc\u7b54\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306e\u81e8\u5e8a\u7684\u6709\u7528\u6027\u3092\u793a\u3057\u5f97\u308b\u3053\u3068\u3092\u6307\u6458\u3057\u307e\u3057\u305f\u3002<\/p>\n<p class=\"text-align-justify\">\u540c\u6c0f\u306f\u8aac\u660e\u3057\u307e\u3057\u305f\u3002\u300c\u8840\u6e05HBV RNA\u306f\u6709\u671b\u306b\u898b\u3048\u3001\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002\u4eca\u5f8c\u6570\u5e74\u9593\u3067\u5f97\u3089\u308c\u308b\u7d50\u679c\u3068\u30c7\u30fc\u30bf\u3092\u697d\u3057\u307f\u306b\u3057\u3066\u3044\u307e\u3059\u3002\u300d<\/p>\n<p class=\"text-align-justify\"><em>HBV\u691c\u67fb\u306e\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u3001Prof Thompson\u3068A\/Prof Douglas\u306e<a href=\"https:\/\/labinsights.com\/ja\/disease-area\/infectious-diseases\/is-hepatitis-b-entering-the-era-of-personalised-medicine\/\" target=\"_blank\" rel=\"noopener\">\u5b8c\u5168\u306a\u30a6\u30a7\u30d3\u30ca\u30fc<\/a>\u3092\u8996\u8074\u3059\u308b\u304b\u3001Lab Insights\u306e\u4ed6\u306e\u8a18\u4e8b\u3092\u78ba\u8a8d\u3057\u3066<a href=\"https:\/\/labinsights.com\/ja\/labinsights-topics\/?topics=show&#038;filter_categories_2=290\" target=\"_blank\" rel=\"noopener\">\u304f\u3060\u3055\u3044\u3002<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>B\u578b\u809d\u708e\uff08HBV\uff09\u306b\u3088\u308b\u6b7b\u4ea1\u7387\u3092\u4e0b\u3052\u3088\u3046\u3068\u3059\u308b\u4e16\u754c\u7684\u306a\u5065\u5eb7\u52aa\u529b\u304c\u9ad8\u307e\u308b\u4e2d\u3001\u4e16\u754c\u4e2d\u306e\u691c\u67fb\u5ba4\u3084\u533b\u7642\u306e\u6307\u5c0e\u8005\u304c\u3001\u6cbb\u7642\u6226\u7565\u3092\u5c0e\u304f\u305f\u3081\u306e\u65b0\u898f\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3092\u958b\u767a\u3057\u3001\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002Roche Diagnostics\u304c\u4e3b\u50ac\u3057\u305f\u6700\u8fd1\u306e\u30a6\u30a7\u30d3\u30ca\u30fc\u3067\u306f\u3001\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u306e\u30a6\u30a4\u30eb\u30b9\u5b66\u5c02\u9580\u5bb62\u540d\u304c\u3001HBV\u8a3a\u65ad\u306e\u6700\u65b0\u306e\u9032\u6b69\u3068\u56fd\u5185\u3067\u306eHBV\u8a3a\u65ad\u306e\u6f5c\u5728\u7684\u306a\u4f7f\u7528\u306b\u3064\u3044\u3066\u8a71\u3057\u307e\u3057\u305f\u3002 \u30a6\u30a7\u30d3\u30ca\u30fc\u3067\u306f\u3001University of Melbourne\u306eSt Vincent\u2019s Hospital\u3067\u6d88\u5316\u5668\u5185\u79d1\u90e8\u9577\u3092\u52d9\u3081\u308bProf Alex Thompson\u3001\u304a\u3088\u3073University of Sydney\u304a\u3088\u3073\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u306eWestmead Institute for Medical Research\u306eStorr Liver Centre\u3067\u51c6\u6559\u6388\u3092\u52d9\u3081\u308bA\/Prof Mark Douglas\u306e\u767a\u8868\u3092\u7279\u96c6\u3057\u307e\u3057\u305f\u3002 HBV\u6e1b\u5c11\u306e\u91cd\u8981\u6027 \u4e16\u754c\u4e2d\u306720\u5104\u4eba\u306e\u4eba\u3005\u304c\u751f\u6daf\u306e\u3044\u305a\u308c\u304b\u306e\u6642\u70b9\u3067HBV\u3092\u767a\u75c7\u3057\u3066\u304a\u308a\u30013\u5104\u4eba\u304c\u6162\u6027\u611f\u67d3\u75c7\u306b\u7f79\u60a3\u3057\u3066\u304a\u308a\u3001HBV\u306f\u4e16\u754c\u7684\u306b\u5927\u304d\u306a\u5065\u5eb7\u554f\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u6cbb\u7642\u3057\u306a\u3051\u308c\u3070\u3001\u6700\u592740%\u306e\u60a3\u8005\u304c\u30a6\u30a4\u30eb\u30b9\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u809d\u786c\u5909\u307e\u305f\u306f\u809d\u81d3\u764c\u3067\u6b7b\u4ea1\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u3053\u308c\u304c\u3001\u516c\u8846\u885b\u751f\u6a5f\u95a2\u304c\u30a6\u30a4\u30eb\u30b9\u3092\u6e1b\u5c11\u53c8\u306f\u6392\u9664\u3059\u308b\u305f\u3081\u306e\u5927\u898f\u6a21\u306a\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\u306e\u305f\u3081\u306bHBV\u3092\u6a19\u7684\u3068\u3057\u305f\u7406\u7531\u3067\u3059\u30022016\u5e74\u306b\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\u306f\u30012030\u5e74\u307e\u3067\u306bHBV\u611f\u67d3\u309290%\u6e1b\u5c11\u3055\u305b\u3001\u6b7b\u4ea1\u309265%\u6e1b\u5c11\u3055\u305b\u308b\u8a08\u753b\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u3002 \u3053\u306e\u8a08\u753b\u306f\u3001\u51fa\u751f\u524d\u307e\u305f\u306f\u51fa\u751f\u4e2d\u306e\u6bcd\u5b50\u611f\u67d3\u3092\u76ee\u6a19\u3068\u3059\u308b\u3053\u3068\u306b\u4f9d\u5b58\u3057\u3066\u304a\u308a\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3001\u691c\u67fb\u3001\u6cbb\u7642\u306b\u3088\u308a\u75be\u60a3\u306e\u8ca0\u62c5\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u3092\u5968\u52b1\u3057\u3066\u3044\u307e\u3059\u3002 \u598a\u5a20\u4e2d\u306e\u6bcd\u89aa\u304b\u3089\u8d64\u3061\u3083\u3093\u3078\u306e\u5782\u76f4\u611f\u67d3\u306b\u7126\u70b9\u3092\u5f53\u3066\u308b\u3053\u3068\u306f\u3001\u6162\u6027\u611f\u67d3\u75c7\u306e\u8ab2\u984c\u306b\u5bfe\u51e6\u3059\u308b\u305f\u3081\u306b\u7279\u306b\u91cd\u8981\u3067\u3059\u3002HBV\u306b\u611f\u67d3\u3057\u305f\u6210\u4eba\u304c\u6162\u6027\u75be\u60a3\u3092\u767a\u75c7\u3059\u308b\u53ef\u80fd\u6027\u306f\u308f\u305a\u304b5%\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u51fa\u7523\u524d\u307e\u305f\u306f\u51fa\u7523\u6642\u306b\u6bcd\u89aa\u304b\u3089\u611f\u67d3\u3057\u305f\u65b0\u751f\u5150\u306e\u6162\u6027\u611f\u67d3\u75c7\u30ea\u30b9\u30af\u306f90%\u3067\u3059\u3002 \u6162\u6027HBV\u306e\u75c7\u4f8b\u306f\u3001\u7d99\u7d9a\u7684\u306a\u51e6\u7f6e\u53ca\u3073\u7d99\u7d9a\u7684\u306a\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3092\u5fc5\u8981\u3068\u3059\u308b\u75c7\u4f8b\u3067\u3042\u308a\u3001\u6700\u3082\u56f0\u96e3\u306a\u3082\u306e\u3068\u306a\u308a\u307e\u3059\u3002 \u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u306b\u304a\u3051\u308bHBV\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u958b\u767a \u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u3067\u306f\u3001\u56fd\u5bb6\u6226\u7565\u306e\u76ee\u6a19\u306f\u3001\u5c0f\u5150\u4e88\u9632\u63a5\u7a2e\u306e\u666e\u53ca\u3001\u3088\u308a\u591a\u304f\u306e\u6162\u6027\u75c7\u4f8b\u3092\u767a\u898b\u3059\u308b\u305f\u3081\u306e\u8a3a\u65ad\u62e1\u5927\u3001\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u304a\u3088\u3073\u305d\u306e\u4ed6\u306e\u6cbb\u7642\u6cd5\u306e\u5229\u7528\u53ef\u80fd\u6027\u306e\u5411\u4e0a\u3067\u3059\u3002Prof Thompson\u3068Prof Douglas\u306f\u3001\u69d8\u3005\u306a\u6297\u539f\u3084\u305d\u306e\u4ed6\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3092\u691c\u67fb\u3057\u3001\u60a3\u8005\u306e\u8a3a\u65ad\u3084\u6cbb\u7642\u4e2d\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306b\u3069\u306e\u3088\u3046\u306b\u4f7f\u7528\u3067\u304d\u308b\u304b\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u3067\u3001\u539f\u56e0\u306b\u8ca2\u732e\u3057\u3066\u3044\u307e\u3059\u3002 \u8868\u9762\u6297\u539f\u306f\u3001HBV\u611f\u67d3\u6642\u304b\u3089\u8840\u6db2\u4e2d\u306b\u898b\u51fa\u3059\u3053\u3068\u304c\u3067\u304d\u3001\u6162\u6027\u60a3\u8005\u306f\u3001\u305d\u308c\u3089\u306e\u6297\u539f\u304c\u3082\u306f\u3084\u691c\u51fa\u3055\u308c\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044\u5834\u5408\u306b\u6a5f\u80fd\u7684\u6cbb\u7652\u72b6\u614b\u3092\u9054\u6210\u3057\u307e\u3059\u3002HBV DNA\u306e\u6e2c\u5b9a\u306f\u3001\u60a3\u8005\u306e\u30a6\u30a4\u30eb\u30b9\u91cf\u53ca\u3073\u51e6\u7f6e\u304c\u6709\u52b9\u3067\u3042\u308b\u304b\u3069\u3046\u304b\u3092\u6c7a\u5b9a\u3059\u308b\u305f\u3081\u306e\u5171\u901a\u306e\u30de\u30fc\u30ab\u30fc\u3092\u8a55\u4fa1\u3059\u308b\u65b9\u6cd5\u3067\u3042\u308b\u304c\u3001HBeAg\u306f\u514d\u75ab\u5236\u5fa1\u306e\u6307\u6a19\u3067\u3059\u3002\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u6d3b\u6027\u306f\u3001HBV\u611f\u67d3\u306e\u7d4c\u904e\u3092\u901a\u3057\u3066\u5909\u5316\u3057\u307e\u3059\u3002 \u300c\u3053\u308c\u3089\u306e\u30de\u30fc\u30ab\u30fc\u3092\u3059\u3079\u3066\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3059\u308b\u65b9\u6cd5\u3092\u77e5\u308a\u3001\u6cbb\u7642\u3092\u958b\u59cb\u3059\u308b\u305f\u3081\u306b\u4f55\u3092\u63a2\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u77e5\u308b\u3053\u3068\u306f\u672c\u5f53\u306b\u91cd\u8981\u3067\u3059\u300d\u3068Prof Douglas\u306f\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002 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