{"id":142929,"date":"2021-10-13T07:21:10","date_gmt":"2021-10-13T07:21:10","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e7%9b%b4%e6%8e%a5%e4%bd%9c%e7%94%a8%e5%9e%8b%e7%b5%8c%e5%8f%a3%e6%8a%97%e5%87%9d%e5%9b%ba%e8%96%ac%ef%bc%88doac%ef%bc%89%e3%81%8a%e3%82%88%e3%81%b3%e6%8e%a5%e8%a7%a6%e7%b5%8c%e8%b7%af%e9%98%bb\/"},"modified":"2026-01-20T12:45:12","modified_gmt":"2026-01-20T12:45:12","slug":"measurement-of-direct-oral-anticoagulants-doacs-and-contact-pathway-inhibitors","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ja\/disease-area\/coagulation\/measurement-of-direct-oral-anticoagulants-doacs-and-contact-pathway-inhibitors\/","title":{"rendered":"\u76f4\u63a5\u4f5c\u7528\u578b\u7d4c\u53e3\u6297\u51dd\u56fa\u85ac\uff08DOAC\uff09\u304a\u3088\u3073\u63a5\u89e6\u7d4c\u8def\u963b\u5bb3\u85ac\u306e\u6e2c\u5b9a"},"content":{"rendered":"

2021\u5e74\u306e\u56fd\u969b\u6b62\u8840\u5b66\u4f1a\uff08ISTH\uff09\u4f1a\u8b70\u3067\u958b\u50ac\u3055\u308c\u305f\u3001Roche Diagnostics\u304c\u30b9\u30dd\u30f3\u30b5\u30fc\u3068\u306a\u308b\u30b5\u30c6\u30e9\u30a4\u30c8\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300cFrom Basic Research to Clinical Data: the Future of Patient Management\u300d\u3067\u3001Prof Jonathan Douxfils\u304c\u3001\u76f4\u63a5\u4f5c\u7528\u578b\u7d4c\u53e3\u6297\u51dd\u56fa\u85ac\uff08DOAC\uff09\u3068\u63a5\u89e6\u7d4c\u8def\u963b\u5bb3\u85ac\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3059\u308b\u3053\u3068\u306e\u4fa1\u5024\u306b\u3064\u3044\u3066\u8a71\u3057\u5408\u3044\u307e\u3057\u305f\u3002 <\/p>\n

DOAC\u306f\u30eb\u30fc\u30c1\u30f3\u306e\u81e8\u5e8a\u691c\u67fb\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3092\u5fc5\u8981\u3068\u305b\u305a\u306b\u958b\u767a\u3055\u308c\u307e\u3057\u305f\u304c\u3001\u85ac\u7269\u66dd\u9732\u304a\u3088\u3073\u6297\u51dd\u56fa\u52b9\u679c\u306e\u8a55\u4fa1\u306f\u3001\u7279\u5b9a\u306e\u81e8\u5e8a\u72b6\u6cc1\u306b\u304a\u3044\u3066\u6709\u7528\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001Prof Douxfils\u306f\u3001\u51fa\u8840\u307e\u305f\u306f\u8840\u6813\u75c7\u306e\u518d\u767a\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u3001DOAC\u306e\u8840\u6f3f\u4e2d\u6fc3\u5ea6\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3059\u308b\u3053\u3068\u306e\u91cd\u8981\u6027\u3092\u5f37\u8abf\u3057\u307e\u3057\u305f\u3002\u7814\u7a76\u3067\u306f\u3001\u3088\u308a\u9ad8\u3044DOAC\u8840\u6f3f\u30ec\u30d9\u30eb\u3068\u3001\u4ed8\u52a0\u7684\u306a\u8840\u6813\u4fdd\u8b77\u3092\u4f34\u308f\u306a\u3044\u51fa\u8840\u5408\u4f75\u75c7\u3068\u306e\u9593\u306e\u95a2\u9023\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002DOAC\u306e\u6295\u4e0e\u3092\u53d7\u3051\u305f\u60a3\u8005\u3067\u306f\u3001\u6700\u8fd1\u306e\u89e3\u6790\u306b\u3088\u308a\u3001\u9ad8\u30ec\u30b9\u30dd\u30f3\u30c0\u30fc\u3067\u306f\u51fa\u8840\u6027\u30a4\u30d9\u30f3\u30c8\u306e\u767a\u751f\u7387\u304c\u9ad8\u304f\u3001\u4f4e\u30ec\u30b9\u30dd\u30f3\u30c0\u30fc\u3067\u306f\u8840\u6813\u6027\u30a4\u30d9\u30f3\u30c8\u306e\u767a\u751f\u7387\u304c\u9ad8\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u500b\u4f53\u9593\u5909\u52d5\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u6297\u51dd\u56fa\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306f\u3001\u60a3\u8005\u306e\u8ee2\u5e30\u3092\u6700\u9069\u5316\u3059\u308b\u305f\u3081\u306e\u500b\u5225\u5316\u3055\u308c\u305f\u7ba1\u7406\u3092\u53ef\u80fd\u306b\u3057\u5f97\u307e\u3059\u3002DOAC\u306e\u6e2c\u5b9a\u304c\u95a2\u5fc3\u306e\u3042\u308b\u4ed6\u306e\u81e8\u5e8a\u72b6\u6cc1\u306b\u306f\u3001\u89e3\u6bd2\u5264\u6295\u4e0e\u3092\u5c0e\u304f\u305f\u3081\u306e\u7dca\u6025\u624b\u8853\u3092\u542b\u3080\u4fb5\u8972\u7684\u51e6\u7f6e\u306e\u524d\u3084\u3001\u6975\u7aef\u306a\u4f53\u91cd\u3092\u6709\u3059\u308b\u60a3\u8005\u306a\u3069\u3001\u4e88\u6e2c\u4e0d\u53ef\u80fd\u306a\u85ac\u7269\u52d5\u614b\u3092\u793a\u3059\u60a3\u8005\u304c\u542b\u307e\u308c\u307e\u3059\u3002DOAC\u306e\u6e2c\u5b9a\u306b\u95a2\u3059\u308b\u8a73\u7d30\u306a\u81e8\u5e8a\u691c\u67fb\u30ac\u30a4\u30c0\u30f3\u30b9\u306b\u3064\u3044\u3066\u306f\u3001International Council for Standardization in Haematology\u306e\u63a8\u5968\u3092\u53c2\u7167\u306e\u3053\u3068[1,2]\u3002<\/p>\n

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\u53c2\u8003\u6587\u732e\uff1a<\/p>\n

[1]<\/a> Gosselin RC, et al.Thromb Haemost 2018;118:437-450
\n[2]<\/a> Douxfils J, et al.Thromb Haemost 2021;121:1008-1020. <\/p>\n","protected":false},"excerpt":{"rendered":"

2021\u5e74\u306e\u56fd\u969b\u6b62\u8840\u5b66\u4f1a\uff08ISTH\uff09\u4f1a\u8b70\u3067\u958b\u50ac\u3055\u308c\u305f\u3001Roche Diagnostics\u304c\u30b9\u30dd\u30f3\u30b5\u30fc\u3068\u306a\u308b\u30b5\u30c6\u30e9\u30a4\u30c8\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u300cFrom Basic Research to Clinical Data: the Future of Patient Management\u300d\u3067\u3001Prof Jonathan Douxfils\u304c\u3001\u76f4\u63a5\u4f5c\u7528\u578b\u7d4c\u53e3\u6297\u51dd\u56fa\u85ac\uff08DOAC\uff09\u3068\u63a5\u89e6\u7d4c\u8def\u963b\u5bb3\u85ac\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3059\u308b\u3053\u3068\u306e\u4fa1\u5024\u306b\u3064\u3044\u3066\u8a71\u3057\u5408\u3044\u307e\u3057\u305f\u3002 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Council for Standardization in Haematology\u306e\u63a8\u5968\u3092\u53c2\u7167\u306e\u3053\u3068[1,2]\u3002 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\u3053\u308c\u3089\u306e\u65b0\u3057\u3044\u6cbb\u7642\u85ac\u306b\u5bfe\u3057\u3066\u306f\u3001\u767a\u8272\u6027\u3001\u86cd\u5149\u767a\u751f\u3001\u8840\u6813\u30d9\u30fc\u30b9\u3001\u6297\u539f\u691c\u51fa\u304a\u3088\u3073\u5168\u4f53\u7684\u306a\u6b62\u8840\u8a66\u9a13\u306b\u57fa\u3065\u304f\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u6f5c\u5728\u7684\u306b\u6709\u3059\u308b\u7279\u5b9a\u306e\u8a66\u9a13\u306e\u958b\u767a\u304c\u63a8\u5968\u3055\u308c\u5f97\u307e\u3059\u3002 \u53c2\u8003\u6587\u732e\uff1a [1] Gosselin RC, et al.Thromb Haemost 2018;118:437-450 [2] Douxfils J, et al.Thromb Haemost 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