{"id":146397,"date":"2021-08-04T03:57:33","date_gmt":"2021-08-04T03:57:33","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%ed%98%88%ec%95%a1-%ec%9d%91%ea%b3%a0-%ec%a7%84%eb%8b%a8%ec%9d%84-%ed%86%b5%ed%95%9c-covid-19-%eb%b0%b1%ec%8b%a0-%ec%a0%91%ec%a2%85-%eb%b0%8f-%ed%99%98%ec%9e%90-%ea%b4%80%eb%a6%ac-%ec%a7%80%ec%9b%90\/"},"modified":"2026-02-18T12:03:09","modified_gmt":"2026-02-18T12:03:09","slug":"how-coagulation-diagnostics-support-covid-19-vaccination-and-patient-management","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ko\/disease-area\/coagulation\/how-coagulation-diagnostics-support-covid-19-vaccination-and-patient-management\/","title":{"rendered":"\ud608\uc561 \uc751\uace0 \uc9c4\ub2e8\uc744 \ud1b5\ud55c COVID-19 \ubc31\uc2e0 \uc811\uc885 \ubc0f \ud658\uc790 \uad00\ub9ac \uc9c0\uc6d0 \ubc29\ubc95"},"content":{"rendered":"

COVID-19 \uac10\uc5fc\uc740 \uc815\ub9e5, \ub3d9\ub9e5\uc5d0\uc11c\uc758 \ud608\uc804\uc99d \ub610\ub294 \ud608\uc804\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ud608\uc804\uc758 \uc704\ud5d8\uc740 COVID-19 \uac10\uc5fc\uc73c\ub85c \ubcd1\uc6d0\uc5d0 \uc785\uc6d0\ud55c \uacbd\uc6b0 \uac00\uc7a5 \ub192\uc73c\uba70, \uc77c\ubc18 \ubcd1\uc6d0 \ubcd1\ub3d9\uc5d0 \uc785\uc6d0\ud55c \uc0ac\ub78c\ub4e4\uc758 \uc57d 5%\uc5d0\uc11c \ubc1c\uc0dd\ud558\uace0 \uc911\ud658\uc790\uc2e4(ICU)\uc758 \uacbd\uc6b0 \ucd5c\ub300 20%\uc758 \ubc1c\uc0dd \ube44\uc728\uc744 \ubcf4\uc785\ub2c8\ub2e4. COVID-19\uc5d0 \uac10\uc5fc\ub418\uc5c8\uc9c0\ub9cc \uc785\uc6d0\uc774 \ud544\uc694\ud558\uc9c0 \uc54a\uc740 \uacbd\uc6b0\uc758 \ud608\uc804 \uc704\ud5d8\uc740 \uc57d 1%\ub85c \ub354 \ub0ae\uc2b5\ub2c8\ub2e4[1].<\/p>\n

\ub9e4\uc6b0 \ub4dc\ubb3c\uc9c0\ub9cc \uc544\ub370\ub178\ubc14\uc774\ub7ec\uc2a4 \uae30\ubc18\uc758 \ubc31\uc2e0 \uc811\uc885\uc740 \ubc31\uc2e0 \uc720\ub3c4 \ud608\uc804\uc131 \ud608\uc18c\ud310 \uac10\uc18c\uc99d(VITT)\uc774\ub77c\ub294 \uc9c8\ud658\uc744 \ud1b5\ud55c \ud608\uc804\uacfc\ub3c4 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. COVID-19 \ubc31\uc2e0 \uc811\uc885 \ubc0f \ud658\uc790 \uad00\ub9ac\uc640 \uad00\ub828\ub41c \uc8fc\uc694 \ud608\uc561 \uc751\uace0 \uc704\ud5d8\uacfc \uace0\ub824 \uc0ac\ud56d\uc744 \ub354 \uc798 \uc774\ud574\ud558\uace0\uc790 Roche Diagnostics Asia Pacific\uc740 \ucd5c\uadfc Singapore General Hospital\uc758 \uc120\uc784 \ucee8\uc124\ud134\ud2b8\uc774\uc790 \ud608\uc561\ud559 \ubd80\uc11c\uc7a5\uc778 Ng Heng Joo \ubc15\uc0ac\uc640 \uc774\uc57c\uae30\ub97c \ub098\ub204\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

COVID-19 \uce58\ub8cc \ubc0f \ubc31\uc2e0 \uc811\uc885 \ud6c4 \ud3c9\uac00\uc758 \ud608\uc561 \uc751\uace0 \ub9c8\ucee4<\/h3>\n

\ub204\uc801\ub418\ub294 \uc2e4\ud5d8\uc2e4 \uc99d\uac70\ub294 COVID-19 \uac10\uc5fc \ud658\uc790\uc758 \ube44\uc815\uc0c1\uc801\uc778 \ud608\uc561 \uc751\uace0 \ubcc0\ud654\ub294 \uadfc\ubcf8\uc801\uc778 \uc5fc\uc99d \ubc18\uc751\uc758 \uacb0\uacfc\uc77c \uc218 \uc788\uc73c\uba70 \uace0\uc720\ud55c \uc751\uace0 \ucd09\uc9c4 \ud6a8\uacfc \uc790\uccb4\uc640\ub294 \uad00\ub828\uc774 \uc5c6\ub2e4\ub294 \uacb0\uacfc\ub97c \uc2dc\uc0ac\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc2ec\uac01\ud55c \uae09\uc131\uae30 \ubc18\uc751\uacfc \uc77c\uce58\ud558\ub294 \uc2ec\uac01\ud55c COVID-19 \uac10\uc5fc \ud658\uc790\uc5d0\uc11c\ub294 \ud608\uc561 \uc751\uace0 \ub2e8\ubc31\uc9c8\uc758 \ud604\uc800\ud55c \uc99d\uac00\uac00 \uc788\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc911\uc99d \ud3d0\ub834 \ud658\uc790 \uc911 \uc77c\ubd80\ub294 \ubc14\uc774\ub7ec\uc2a4 \ud328\ud608\uc99d, \ud30c\uc885 \ud608\uad00 \ub0b4 \uc751\uace0(DIC) \ubc0f \ub2e4\ubc1c\uc131 \uc7a5\uae30 \ubd80\uc804\uc774 \ubc1c\uc0dd\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

D-\uc774\ub7c9\uccb4\ub294 \ud608\uc804\uc99d \ud658\uc790\uc758 \uc591\uc131 \ub9c8\ucee4\ub77c\ub294 \uc810 \ub54c\ubb38\uc5d0 D-\uc774\ub7c9\uccb4\ub97c COVID-19\uc758 \uc911\uc99d\ub3c4 \uc608\uce21\uc5d0 \ud1b5\ud569\ud558\ub824\ub294 \uc5f0\uad6c\uac00 \uc774\ub8e8\uc5b4\uc84c\uc2b5\ub2c8\ub2e4. Ng \ubc15\uc0ac\ub294 \u201cD-\uc774\ub7c9\uccb4\ub294 COVID-19 \ud658\uc790\uc758 \uc815\ub9e5 \ud608\uc804 \uc0c9\uc804\uc99d \ubc1c\uc0dd\uc5d0 \ub300\ud55c \uc704\ud5d8 \ud3c9\uac00 \uc810\uc218 \uc911 \uc77c\ubd80\uc5d0 \ud1b5\ud569\ub418\uc5c8\ub2e4. \uc9c8\ubcd1\uc758 \uc911\uc99d\ub3c4 \uc99d\uac00\uc5d0 \ub300\ud55c \uc6b0\ub824\ub97c \uad6c\uc131\ud558\ub294 \ucef7\uc624\ud504 \uc218\uce58\ub97c \uc815\uc758\ud558\uace0 \uadf8\uac83\uc774 \ud658\uc790\uc5d0 \ub300\ud55c \uce58\ub8cc\uc758 \uc99d\ub300\uc5d0 \uc5b4\ub5bb\uac8c \uc601\ud5a5\uc744 \ubbf8\uce60\uc9c0 \uc815\uc758\ud558\uae30\uac00 \ub2e4\uc18c \uc5b4\ub824\uc6e0\ub2e4\u201d\uace0 \ub9d0\ud558\uba70<\/p>\n

\u201c\uc0ac\uc6a9\ub41c \uc77c\ubd80 \uc704\ud5d8 \ud3c9\uac00 \ubaa8\ub378\uc758 \uc77c\ubc18\uc801\uc778 \uc608\uc5d0\ub294 \uac1c\uc120\ub41c D-\uc774\ub7c9\uccb4 \uc810\uc218\uc640 \uce74\ud504\ub9ac\ub2c8 \uc810\uc218\uac00 \ud3ec\ud568\ub41c\ub2e4\u201d\uace0 \ub367\ubd99\uc600\uc2b5\ub2c8\ub2e4. “\uc77c\ubd80 \uac80\uc99d \uc5f0\uad6c\ub294 \ud658\uc790 \uc911 \uc5b4\ub290 \uac83\uc774 \uc815\ub9e5 \ud608\uc804 \uc0c9\uc804\uc99d \ubc1c\ubcd1\uc758 \uc800\uc704\ud5d8, \uc911\uac04 \uc704\ud5d8 \ub610\ub294 \uace0\uc704\ud5d8\uc73c\ub85c \ubd84\ub958\ub420 \uc218 \uc788\ub294\uc9c0 \uc608\uce21\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774\ub418\uba70 \ud658\uc790\uc5d0 \ub300\ud55c \ud56d\uc751\uace0 \uc694\ubc95\uc758 \uc801\uc808\ud55c \uc0ac\uc6a9\uc744 \uc608\uce21\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774\ub41c\ub2e4\ub294 \uac83\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4.”<\/p>\n

VITT \ud658\uc790\uc758 \uacbd\uc6b0, \uac80\uc0ac \uacb0\uacfc \uc77c\ubc18\uc801\uc73c\ub85c \uc12c\uc720\uc18c\uc6d0\uc774 \ub0ae\uace0, \uc815\ub9e5 \ud608\uc804\uc0c9\uc804\uc99d\uc5d0\uc11c \uc77c\ubc18\uc801\uc73c\ub85c \uc608\uc0c1\ub418\ub294 \uc218\uc900\ubcf4\ub2e4 D-\uc774\ub7c9\uccb4 \uc218\uce58\uac00 \ub9e4\uc6b0 \ub192\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. Ng \ubc15\uc0ac\ub294 \ub2e4\uc74c\uacfc \uac19\uc774 \uac15\uc870\ud588\uc2b5\ub2c8\ub2e4. \u201c\uc6b0\ub9ac\ub294 VITT\uc5d0 \ub300\ud55c \uc7a0\uc7ac\uc801 \ubc1c\ubcd1 \uc2dc\uae30\uac00 \uc77c\ubc18\uc801\uc73c\ub85c \uc608\ubc29 \uc811\uc885 \ud6c4 5~28\uc77c \uc0ac\uc774\uc774\ub77c\ub294 \uac83\uacfc VITT\ub294 \ube44\uc7a5 \uc815\ub9e5 \ud608\uc804\uc99d\ubfd0\ub9cc \uc544\ub2c8\ub77c \ub300\uc815\ub9e5\ub3d9 \ud608\uc804\uc99d\uacfc \uac19\uc740 \ud754\uce58 \uc54a\uc740 \ubd80\uc704\uc5d0\uc11c\uc758 \ud608\uc804\uc99d\uc744 \uc720\ubc1c\ud55c\ub2e4\ub294 \uac83\uc744 \uc54c\uace0 \uc788\ub2e4.\u201d<\/p>\n

VITT \ud658\uc790\uc5d0\uc11c \ud608\uc18c\ud310 \uc81c4\uc778\uc790(PF4)\uc5d0 \ub300\ud55c \ud56d\uccb4\uac00 \ud655\uc778\ub418\uc5c8\uae30 \ub54c\ubb38\uc5d0, \ud5e4\ud30c\ub9b0 \uce58\ub8cc\uc5d0 \ub300\ud55c \uc774\uc804 \ub178\ucd9c\uc774 \uc5c6\uc74c\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \ud5e4\ud30c\ub9b0 \uc720\ubc1c \ud608\uc18c\ud310 \uac10\uc18c\uc99d(HIT)\uacfc \uc720\uc0ac\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ud56d-PF4 \ud56d\uccb4\ub294 ELISA HIT \ubd84\uc11d\uc73c\ub85c \uac80\ucd9c\ud560 \uc218 \uc788\uc9c0\ub9cc \uc77c\ubc18\uc801\uc73c\ub85c \ud654\ud559\ubc1c\uad11 \ubc0f \ub77c\ud14d\uc2a4 \ubd84\uc11d\uc744 \uae30\ubc18\uc73c\ub85c \ud558\ub294 \uc2e0\uc18d\ud55c \uac80\uc0ac\uc5d0\uc11c\ub294 \uac80\ucd9c\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

COVID-19 \uc2dc\ub300\uc5d0 \ud608\uc561 \uc751\uace0 \uac80\uc0ac\uc2e4\uc5d0\uc11c\uc758 \uc5b4\ub824\uc6c0<\/h3>\n

COVID-19\ub294 \ud608\uc804\uc99d\uacfc\uc758 \uc5f0\uad00\uc131\uc744 \ud1b5\ud574 \ud658\uc790 \uc9c4\ub2e8 \ubc0f \uad00\ub9ac\uc5d0 \ub9ce\uc740 \uc5b4\ub824\uc6c0\uc744 \ubd88\ub7ec\uc77c\uc73c\ucf30\uc2b5\ub2c8\ub2e4. \ud32c\ub370\ubbf9 \ucd08\uae30 \ub2e8\uacc4\uc5d0\uc11c \uc774\ub7ec\ud55c \uacfc\uc81c \uc911 \ud558\ub098\ub294 COVID-19 \ud658\uc790\uc758 \ubcd1\ud0dc\uc0dd\ub9ac\ud559 \ub610\ub294 \ud608\uc804\uc99d\uc758 \uc5ed\ud560\uc744 \uc774\ud574\ud558\ub294 \uac83\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ubbc0\ub85c \uace0\uc704\ud5d8\uad70 \ubc0f \ud574\ub2f9 \ud658\uc790\uad70\uc5d0 \ub300\ud55c \ud56d\uc751\uace0 \uc694\ubc95\uc758 \uc5ed\ud560\uc744 \uacc4\uce35\ud654\ud558\ub824\ub294 \uc2dc\ub3c4\ub294 \ub09c\uad00\uc5d0 \ubd80\ub52a\ud788\ub294 \uacfc\uc81c\uc600\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub610 \ub2e4\ub978 \uc9c4\ub2e8 \uacfc\uc81c\ub294 VITT\uc758 \uc2e4\uccb4\uc600\uc2b5\ub2c8\ub2e4. HIT\uc5d0 \ub300\ud55c \ud56d-PF4 \ud56d\uccb4\uc5d0 \ub300\ud55c \uac80\uc0ac\ub294 \uc798 \ud655\ub9bd\ub418\uc5b4 \uc788\uc9c0\ub9cc VITT \ud658\uc790\uc5d0 \ub300\ud55c \uc6a9\ub3c4\uc640 \ubbfc\uac10\ub3c4\ub294 \uadf8\uc640 \ub69c\ub837\uc774 \ub2e4\ub974\uace0 \ucc28\uc774\uac00 \uc788\uc2b5\ub2c8\ub2e4. \ub2e8\uc21c\ud788 \ud56d-PF4 \ud56d\uccb4\uc758 \uc2e4\uc99d\uc5d0 \ub300\ud55c \ucd94\uac00 \ubcf4\uc870 \uc218\ub2e8\uc73c\ub85c\uc368, \ud608\uc18c\ud310\uc744 \ud65c\uc131\ud654\ud558\ub294 \ud56d\uccb4\uc758 \uc874\uc7ac\ub97c \ud655\uc778\ud558\uae30 \uc704\ud574 \uac1c\ubc1c\ub41c \ucd94\uac00 \uac80\uc0ac\uac00 \uc788\uc5c8\uc2b5\ub2c8\ub2e4[2].<\/p>\n

\uc774\ub7ec\ud55c \uc5b4\ub824\uc6c0\uc740 \uac00\ub2a5\ud55c \uac80\uc0ac, \uc608\ub97c \ub4e4\uc5b4 \ud5e4\ud30c\ub9b0 \uc720\ub3c4 \ud608\uc18c\ud310 \uc751\uc9d1 \ubd84\uc11d(HIPAA)\uc744 \ud65c\uc6a9\ud558\ub294 \ucd94\uac00 \uac80\uc0ac\uc758 \uac1c\ubc1c\ub85c \uc774\uc5b4\uc84c\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc790\ub4e4\uc740 HIPAA \uac80\uc0ac\ub97c \ubcc0\ud615\ud558\uc5ec VITT \ud658\uc790\uc758 \ubcd1\uc778 \ub610\ub294 \uc9c4\ub2e8\uc744 \ub354 \uc798 \uc815\uc758\ud558\uae30 \uc704\ud574 \ud608\uc18c\ud310 \uc81c4\uc778\uc790 \uc720\ub3c4 \ud608\uc18c\ud310 \uc751\uc9d1 \uac80\uc0ac\ub97c \uac1c\ubc1c\ud588\uc2b5\ub2c8\ub2e4. \ud750\ub984 \uc138\ud3ec \uce21\uc815\ubc95\uc744 \ud65c\uc6a9\ud55c \ud608\uc18c\ud310 \ud65c\uc131\ud654 \ub610\ub294 \ud56d\uccb4\uac00 \uc2e4\ud5d8\uc2e4\uc5d0\uc11c \ud14c\uc2a4\ud2b8\ub85c \uc0ac\uc6a9\ub418\uc5b4 \uc654\uc2b5\ub2c8\ub2e4. \uc774 \uac80\uc0ac\ub4e4\uc740 \uc720\uc6a9\ud558\uace0 \uac1c\ubc1c\uc5d0 \ub09c\uad00\uc774 \uc788\uc5c8\uc9c0\ub9cc VITT \uc9c4\ub2e8\uc5d0 \uadf8 \ud6a8\uacfc\ub97c \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ucc28\uc138\ub300 \ud608\uc561 \uc751\uace0 \uc9c4\ub2e8<\/h3>\n

COVID-19\uc744 \uc778\ud55c \ud608\uc561 \uc751\uace0 \ubcd1\uc99d\uc740 D-\uc774\ub7c9\uccb4\uc758 \ud604\uc800\ud55c \uc0c1\uc2b9\uc744 \ub098\ud0c0\ub0b4\ub294 \ubcc4\ub3c4\uc758 \uc99d\uc0c1\uc785\ub2c8\ub2e4. COVID-19\ub294 \ubbf8\uc138\ud608\uad00 \ubc0f \ub300\ud608\uad00 \ud608\uc804\uc99d\uc758 \ub192\uc740 \uc704\ud5d8\uacfc \ud56d\uc751\uace0 \ubd80\uc804\uc758 \ubc1c\uc0dd\ub960 \uc99d\uac00\uc640 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uae30\uc874\uc758 \ud328\ud608\uc99d\uacfc \ub2ec\ub9ac \ud56d\uc751\uace0\uc81c\ub294 \ucf54\ub85c\ub09819 \uad00\ub9ac\uc5d0\uc11c\uc758 \ud575\uc2ec \uc5ed\ud560\ub85c \uc0dd\uc874\uc5d0 \uae0d\uc815\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \ubc14\uc774\uc624\ub9c8\ucee4\ub97c \ube44\ub86f\ud55c \ub2e4\uc591\ud55c \uc810\uc218 \uc2dc\uc2a4\ud15c\uc740 COVID-19\uc5d0\uc11c \ubc31\uc2e0 \uc811\uc885 \ud6c4 \ud608\uc804\uc744 \uc9c4\ub2e8\ud560 \ubfd0\ub9cc \uc544\ub2c8\ub77c \ud56d\uc751\uace0 \ubaa9\uc801\uc73c\ub85c \ud658\uc790\ub97c \uc704\ud5d8 \ubc94\uc8fc\ub85c \ubd84\ub958\ud558\ub294 \ub370\ub3c4 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ucc38\uace0 \ubb38\ud5cc:<\/em><\/p>\n

[1]<\/a> ISTH experts explain new Blood Clotting phenomenon in hospitalized COVID-19 patients.<\/p>\n

[2]<\/a>\u00a0Scully, M.et al (2021). Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination. New England Journal of Medicine. 384.pp2202-2211.<\/p>\n","protected":false},"excerpt":{"rendered":"

COVID-19 \uac10\uc5fc\uc740 \uc815\ub9e5, \ub3d9\ub9e5\uc5d0\uc11c\uc758 \ud608\uc804\uc99d \ub610\ub294 \ud608\uc804\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ud608\uc804\uc758 \uc704\ud5d8\uc740 COVID-19 \uac10\uc5fc\uc73c\ub85c \ubcd1\uc6d0\uc5d0 \uc785\uc6d0\ud55c \uacbd\uc6b0 \uac00\uc7a5 \ub192\uc73c\uba70, \uc77c\ubc18 \ubcd1\uc6d0 \ubcd1\ub3d9\uc5d0 \uc785\uc6d0\ud55c \uc0ac\ub78c\ub4e4\uc758 \uc57d 5%\uc5d0\uc11c \ubc1c\uc0dd\ud558\uace0 \uc911\ud658\uc790\uc2e4(ICU)\uc758 \uacbd\uc6b0 \ucd5c\ub300 20%\uc758 \ubc1c\uc0dd \ube44\uc728\uc744 \ubcf4\uc785\ub2c8\ub2e4. COVID-19\uc5d0 \uac10\uc5fc\ub418\uc5c8\uc9c0\ub9cc \uc785\uc6d0\uc774 \ud544\uc694\ud558\uc9c0 \uc54a\uc740 \uacbd\uc6b0\uc758 \ud608\uc804 \uc704\ud5d8\uc740 \uc57d 1%\ub85c \ub354 \ub0ae\uc2b5\ub2c8\ub2e4[1]. \ub9e4\uc6b0 \ub4dc\ubb3c\uc9c0\ub9cc \uc544\ub370\ub178\ubc14\uc774\ub7ec\uc2a4 \uae30\ubc18\uc758 \ubc31\uc2e0 \uc811\uc885\uc740 \ubc31\uc2e0 \uc720\ub3c4 \ud608\uc804\uc131 \ud608\uc18c\ud310 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