{"id":146401,"date":"2020-08-31T02:47:29","date_gmt":"2020-08-31T02:47:29","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/il-6-%ec%95%84%ec%8b%9c%ec%95%84-%ed%83%9c%ed%8f%89%ec%96%91-%ec%a7%80%ec%97%ad%ec%9d%98-covid-19-%ea%b4%80%eb%a6%ac%eb%a5%bc-%ec%9c%84%ed%95%9c-%ea%b0%80%eb%8a%a5%ec%84%b1%ec%9d%84-%eb%b3%b4\/"},"modified":"2026-02-18T12:06:35","modified_gmt":"2026-02-18T12:06:35","slug":"il-6-shows-promise-for-covid-19-management-in-asia-pacific","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ko\/disease-area\/critical-care\/il-6-shows-promise-for-covid-19-management-in-asia-pacific\/","title":{"rendered":"IL-6, \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc758 COVID-19 \uad00\ub9ac\ub97c \uc704\ud55c \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc8fc\ub2e4"},"content":{"rendered":"

COVID-19 \ud32c\ub370\ubbf9\uc5d0 \ub9de\uc11c \uc2f8\uc6b0\ub294 \uacfc\uc815\uc5d0\uc11c \ub9ce\uc740 \ubcf4\uac74 \uc758\ub8cc \uc2dc\uc2a4\ud15c\uc774 \uc778\ud130\ub958\ud0a8-6(IL-6)\ub97c \uc9c4\ub2e8 \ub3c4\uad6c \uc138\ud2b8\uc5d0 \ucd94\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc911\uc99d COVID-19\uc758 \uc870\uae30 \uc608\uce21 \uc9c0\ud45c\ub85c\uc11c IL-6\ub294 \uc27d\uac8c \ucc44\ucde8\ud560 \uc218 \uc788\ub294 \uc0dd\ubb3c\ud559\uc801 \uc2dc\ub8cc(\ud608\uccad \ub610\ub294 \ud608\uc7a5)\uc5d0\uc11c \uac80\ucd9c\ud560 \uc218 \uc788\uace0, \uc798 \uac80\uc99d\ub41c \uc2e0\uc18d\ud55c \ubd84\uc11d \uc2dc\uc2a4\ud15c\uc744 \ud1b5\ud574 \uce21\uc815\ud560 \uc218 \uc788\uae30 \ub54c\ubb38\uc5d0 \uc774\uc0c1\uc801\uc778 \uc608\ud6c4 \ubc14\uc774\uc624\ub9c8\ucee4\uc785\ub2c8\ub2e4. \uc810\uc810 \ub354 \ub9ce\uc740 \uc5f0\uad6c \uacb0\uacfc\uac00 IL-6\uac00 \uc911\uc99d COVID-19 \uad00\ub9ac\uc758 \ud544\uc218\uc801\uc778 \ubd80\ubd84\uc73c\ub85c \uc790\ub9ac \uc7a1\uc744 \uac00\ub2a5\uc131\uc774 \uc788\uc74c\uc744 \ubcf4\uc5ec \uc8fc\uace0 \uc788\uc2b5\ub2c8\ub2e4[1]. \ucd5c\uadfc Roche Diagnostics\uac00 \uc8fc\ucd5c\ud55c \uc6e8\ube44\ub098\uc5d0\uc11c University of Washington Department of Global Health\uc758 \uad50\uc218 \ubc0f \ubd80\uc758\uc7a5\uc778 Dr Conrad Liles\uc640 Ludwig Maximilian University Hospital\uc758 \uc120\uc784 \uc758\uc0ac\uc778 Dr Tobias Weinberger\uac00 COVID-19 \uad00\ub9ac\uc5d0\uc11c \ubc14\uc774\uc624\ub9c8\ucee4\ub85c\uc11c IL-6\uc758 \uc5ed\ud560\uc5d0 \ub300\ud574 \ub17c\uc758\ud588\uc2b5\ub2c8\ub2e4. \uc774\ubc88 \uc6e8\ube44\ub098\ub294 \ubbf8\uad6d\uacfc \ub3c5\uc77c\uc758 \uc784\uc0c1 \uc5f0\uad6c\uc640 \uc0ac\ub840 \uacf5\uc720\ub97c \uc911\uc2ec\uc73c\ub85c \uc9c4\ud589\ub418\uc5c8\uc9c0\ub9cc, \ud2b9\ud788 \uc911\uc99d \ubc0f \uc704\uc911\ud55c \ud658\uc790 \uc0ac\ub840\uc758 \ube44\uc728\uc774 \ub192\uc740 \uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc758 \uc5ec\ub7ec \uc758\ub8cc \uc2dc\uc2a4\ud15c\uc5d0\ub3c4 \uad00\ub828\uc131 \uc788\ub294 \ud1b5\ucc30\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

\ud638\ud761 \ubd80\uc804\uc758 \uc870\uae30 \uc608\uce21 \uc9c0\ud45c<\/h2>\n

IL-6\ub294 \ub2e4\uba74 \ubc1c\ud604\uc131 \uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778\uc73c\ub85c, \uc911\uc99d COVID-19 \ud658\uc790\uc5d0\uc11c \ub098\ud0c0\ub098\ub294 \uc0ac\uc774\ud1a0\uce74\uc778 \ubc1c\uc791\uc758 \uc8fc\uc694 \uad6c\uc131 \uc694\uc18c\uc785\ub2c8\ub2e4. \ud608\uccad \ub610\ub294 \ud608\uc7a5 \ub0b4 IL-6\uc758 \uc0c1\uc2b9\uc740 COVID-19 \ud658\uc790\uc5d0\uac8c\uc11c \uac00\uc7a5 \ub9ce\uc774 \ubcf4\uace0\ub41c \uc0ac\uc774\ud1a0\uce74\uc778 \uc774\uc0c1\uc785\ub2c8\ub2e4[2]. \uc911\uad6d\uc758 \uc778\uad6c \uc9d1\ub2e8\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \uc5ec\ub7ec \uc5f0\uad6c\uc5d0\uc11c\ub3c4 IL-6 \uc0c1\uc2b9\uc774 \ubd88\ub7c9\ud55c \uc608\ud6c4 \ubc0f \ub192\uc740 \uc0ac\ub9dd\ub960\uacfc \uad00\ub828 \uc788\uc74c\uc774 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4[3-5]. \ud3d0 \ub300\uc2dd \uc138\ud3ec\ub294 \ud608\uc561 \ub2e8\ud575\uad6c\ubcf4\ub2e4 \ub354 \ub192\uc740 \uc218\uc900\uc758 IL-6\ub97c \ubc1c\ud604\ud558\ubbc0\ub85c, Dr Weinberger\ub294 “IL-6\ub294 \ud3d0 \uc0c1\ud0dc\ub97c \uc5ff\ubcfc \uc218 \uc788\ub294 \ucc3d \uc5ed\ud560\uc744 \ud560 \uc218 \uc788\uc73c\uba70 \uc9c8\ubcd1 \uc911\uc99d\ub3c4\ub97c \ud3c9\uac00\ud558\ub294 \uc720\uc6a9\ud55c \uc9c4\ub2e8 \ub3c4\uad6c\uac00 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.”\ub77c\uace0 \uc5b8\uae09\ud588\uc2b5\ub2c8\ub2e4. Dr Weinberger \uc5f0\uad6c\ud300\uc774 \uc218\ud589\ud55c \uc804\ud5a5\uc801 \ucf54\ud638\ud2b8 \uc5f0\uad6c\uc5d0\uc11c\ub294 Ludwig Maximilian University Hospital\uc5d0 \uc785\uc6d0\ud55c 89\uba85\uc758 COVID-19 \ud658\uc790\uc5d0\uc11c IL-6 \uc0c1\uc2b9\uc774 \uae30\uacc4 \ud658\uae30\uc758 \ud544\uc694\uc131\uc744 \ub9e4\uc6b0 \uc815\ud655\ud558\uac8c \uc608\uce21\ud55c\ub2e4\ub294 \uacb0\uacfc\uac00 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4[6]. \uc0bd\uad00 \uc804 IL-6 \ucd5c\ub300 \uc218\uce58\ub294 80pg\/ml \uae30\uc900\uc810\uc5d0\uc11c \uc591\uc131 \ubc0f \uc74c\uc131 \uc608\uce21\uac12(\uac01\uac01 74%\uc640 83%)\uacfc \uac00\uc7a5 \uac15\ud55c \uc5f0\uad00\uc131\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \ud1b5\ud569 \ucf54\ud638\ud2b8\uc5d0\uc11c IL-6\ub294 \ud658\uc790\uac00 \uc2e4\uc81c\ub85c \uc0bd\uad00\uc744 \ubc1b\uae30 \ucd5c\ub300 23.2\uc2dc\uac04 \uc804\uc5d0 \uadf8 \ud544\uc694\uc131\uc744 \uc608\uce21\ud588\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0\uc11c IL-6 \ucd5c\ub300 \uc218\uce58\uc758 \uc608\uce21\uac12\uc774 \uc785\uc99d\ub418\uc5c8\uc74c\uc5d0\ub3c4, Dr Weinberger\ub294 \ucd08\uae30 \ud3c9\uac00 \uc2dc IL-6 \uac80\uc0ac\ub97c \uc77c\ubc18\uc801\uc73c\ub85c \uad8c\uc7a5\ud569\ub2c8\ub2e4. \uc774\ub294 IL-6\uac00 35pg\/ml\uc758 \ub0ae\uc740 \uae30\uc900 \uc784\uacd7\uac12\uc5d0\uc11c\ub3c4 \ud638\ud761 \ubd80\uc804 \uc704\ud5d8\uc774 \uc788\ub294 \ud658\uc790\ub97c \ubc1c\uacac\ud558\ub294 \ub370 \uc788\uc5b4 \ub192\uc740 \ubbfc\uac10\ub3c4\ub97c \uc720\uc9c0\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. University of Washington Medical Center\uc5d0\uc11c\ub294 \uc800\uc0b0\uc18c\uc99d \ub4f1 \uc784\uc0c1\uc801 \uc545\ud654 \uc9d5\ud6c4\ub97c \ubcf4\uc774\uc9c0\ub9cc \uc0bd\uad00\ub418\uac70\ub098 ICU\uc5d0 \uc788\uc9c0\ub294 \uc54a\uc740 \uc785\uc6d0 \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c IL-6 \uc218\uce58\ub97c \uce21\uc815\ud569\ub2c8\ub2e4. Dr Liles\ub294 “\uc6b0\ub9ac\uc758 \uc811\uadfc\ubc95\uc740 \uae30\uacc4 \ud658\uae30\uc758 \ud544\uc694\uc131\uc744 \uc904\uc774\uace0 \ud3d0 \uc9c8\ud658\uc758 \uc9c4\ud589\uc744 \uba48\ucd94\uae30 \uc704\ud574 \ud658\uc790\ub97c \uce58\ub8cc\ud558\ub294 \uac83\uc785\ub2c8\ub2e4. COVID\ub85c \uc778\ud55c \uae09\uc131 \uc800\uc0b0\uc18c \ud608\uc131 \ud638\ud761 \ubd80\uc804\uc774 \uc788\ub294 \ud658\uc790\uc5d0\uc11c \uc0bd\uad00 \uc804\uc5d0 \uae09\uc131 \ud3d0 \uc190\uc0c1\uc744 \uc608\ubc29\ud558\ub294 \uac83\uc774 \ubaa9\ud45c\uc785\ub2c8\ub2e4.”\ub77c\uace0 \ubc1d\ud614\uc2b5\ub2c8\ub2e4. Dr Weinberger\ub294 \uad11\ubc94\uc704\ud55c \uc9c8\ubcd1 \uacbd\uacfc\uc640 \ubb34\uc99d\uc0c1 \uc800\uc0b0\uc18c\uc99d\uc73c\ub85c \uc778\ud574 COVID-19 \ud658\uc790\ub4e4\uc758 \uc608\ud6c4\ub97c \ud3c9\uac00\ud558\uae30 \uc5b4\ub835\ub2e4\uace0 \uac15\uc870\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub294 \uc720\uc0ac\ud55c \uc99d\uc0c1\uc744 \ubcf4\uc778 \ub450 \uba85\uc758 \ud658\uc790 \uc0ac\ub840\ub97c \uc81c\uc2dc\ud588\uc73c\uba70, \uadf8\uc911 \ud55c \uba85\uc740 \uc774\ud2c0 \ub0b4\uc5d0 \uc784\uc0c1 \uc0c1\ud0dc\uac00 \ube60\ub974\uac8c \uc545\ud654\ub418\uc5b4 \uacb0\uad6d \uc0bd\uad00\uc774 \ud544\uc694\ud588\uc2b5\ub2c8\ub2e4(\uadf8\ub9bc 1). \uadf8\ub294 \uc5ec\uae30\uc11c IL-6\uc640 \uac19\uc740 \uac80\uc0ac\uc2e4 \uc9c0\ud45c\uac00 \ubb34\uc99d\uc0c1 \uc800\uc0b0\uc18c\uc99d \ud658\uc790\uc5d0\uc11c \uc778\uacf5\ud638\ud761\uae30 \uc9c0\uc6d0\uc758 \ud544\uc694\uc131\uc744 \ud30c\uc545\ud558\ub294 \ub370 \uc720\uc6a9\ud558\ub2e4\ub294 \uc810\uc744 \ub2e4\uc2dc \uac15\uc870\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\"IL6clinicalcases\"
\uadf8\ub9bc 1: Dr Weinberger\uac00 \ubc1c\ud45c\ud55c COVID-19 \uc784\uc0c1 \uc0ac\ub840<\/figcaption><\/figure>\n

\uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc5d0\uc11c \ub192\uc544\uc9c0\ub294 IL-6\uc5d0 \ub300\ud55c \uad00\uc2ec<\/h2>\n

\uc544\uc2dc\uc544 \ud0dc\ud3c9\uc591 \uc9c0\uc5ed\uc5d0\uc11c\ub294 COVID-19 \uad00\ub9ac\uc5d0 \uc788\uc5b4 \ubc14\uc774\uc624\ub9c8\ucee4\ub85c\uc11c IL-6\uc758 \ud65c\uc6a9 \uac00\ub2a5\uc131\uc774 \ud65c\ubc1c\ud788 \ud0d0\uc0c9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc911\uad6d\uc5d0\uc11c\ub294 \ud2b9\ud788 Chinese Clinical Guidance for COVID-19 Pneumonia Diagnosis(7\ud310)\uc5d0 \uc131\uc778 \uc911\uc99d \ubc0f \uc704\uc911 \uc0ac\ub840\uc758 \uc9c0\ud45c\ub85c \uad6c\uccb4\uc801\uc73c\ub85c \uc5b8\uae09\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4[7]. \uc778\ub3c4 \ubc0f \ub2e4\ub978 \uad6d\uac00\uc758 \uc784\uc0c1 \uc774\ud574\uad00\uacc4\uc790\ub3c4 \uc774\uc5d0 \uad00\uc2ec\uc744 \ubcf4\uc774\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub2e4\ub978 \uc5fc\uc99d\uc131 \ubc14\uc774\uc624\ub9c8\ucee4(\uc608: \ud398\ub9ac\ud2f4, C-\ubc18\uc751 \ub2e8\ubc31\uc9c8)\uc640 \ube44\uad50\ud588\uc744 \ub54c, IL-6\ub294 \ud638\ud761 \ubd80\uc804\uc758 \uc870\uae30 \uc608\uce21 \uc778\uc790\ub85c\uc11c \uc758\uc0ac\uac00 \uc9d1\uc911 \uce58\ub8cc \uacc4\ud68d\uc744 \uc9dc\uac70\ub098 \uce58\ub8cc \uac15\ub3c4\ub97c \uc801\uc808\ud788 \ub192\uc77c \uc218 \uc788\ub3c4\ub85d \uc704\uc911\ud55c \ud658\uc790\ub97c \ub354 \uc2e0\uc18d\ud558\uace0 \ud6a8\uacfc\uc801\uc73c\ub85c \uc2dd\ubcc4\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc904 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uce21\uba74\uc5d0\uc11c IL-6 \ud3c9\uac00\ub294 \uc778\ub3c4\ub124\uc2dc\uc544\uc640 \uac19\uc774 ICU \ubcd1\uc0c1 \uc810\uc720\uc728\uacfc \uc0ac\ub9dd\ub960\uc774 \ub192\uc740 \uc544\uc2dc\uc544 \uad6d\uac00\uc5d0\uc11c \ud2b9\ud788 \uc720\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4[8]. COVID-19 \uad00\ub9ac\uc5d0\uc11c IL-6\uc758 \uc5ed\ud560\uc5d0 \ub300\ud574 \ub354 \uc54c\uc544\ubcf4\uace0 \uc2f6\uc73c\uc138\uc694? \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc5ec \uc6e8\ube44\ub098 \ub179\ud654\ubcf8\uc744 \uc2dc\uccad\ud558\uc138\uc694.<\/p>\n

\ucc38\uace0 \ubb38\ud5cc:<\/em><\/p>\n

[1]<\/a> Del Valle DM, Kim-Schulze S, Huang H-H, et al. An inflammatory cytokine signature predicts COVID-19 severity and survival. Nat Med. Published online August 24, 2020:1-8.<\/em><\/p>\n

[2]<\/a>\u00a0Ragab D, Salah Eldin H, Taeimah M, Khattab R, Salem R.The COVID-19 Cytokine Storm; What We Know So Far. Front Immunol. 2020;11.<\/em><\/p>\n

[3]<\/a>\u00a0Liu Z, Li J, Chen D, et al. Dynamic Interleukin-6 Level Changes as a Prognostic Indicator in Patients With COVID-19. Front Pharmacol. 2020;11.<\/em><\/p>\n

[4]<\/a>\u00a0Chen X, Zhao B, Qu Y, et al. Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019. Clin Infect Dis.<\/em><\/p>\n

[5]<\/a>\u00a0Ruan Q, Yang K, Wang W, Jiang L, Song J.Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. 2020;46(5):846-848. \u00a0<\/em><\/p>\n

[6]<\/a>\u00a0Herold T, Jurinovic V, Arnreich C, et al. Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19. J Allergy Clin Immunol. 2020;146(1):128-136.e4.<\/em><\/p>\n

[7]\u00a0Chinese Clinical Guidance for COVID-19 Pneumonia Diagnosis and Treatment (7th edition) \u6297\u51fb\u65b0\u51a0\u80ba\u708e. 2020\ub144 8\uc6d4 10\uc77c\uc5d0 \uc561\uc138\uc2a4\ud568. <\/em><\/p>\n

[8] Jakarta’s Covid-19 Response Team. Jakarta’s Covid-19 Response Team. 2020\ub144 8\uc6d4 25\uc77c\uc5d0 \uc561\uc138\uc2a4\ud568.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

COVID-19 \ud32c\ub370\ubbf9\uc5d0 \ub9de\uc11c \uc2f8\uc6b0\ub294 \uacfc\uc815\uc5d0\uc11c \ub9ce\uc740 \ubcf4\uac74 \uc758\ub8cc \uc2dc\uc2a4\ud15c\uc774 \uc778\ud130\ub958\ud0a8-6(IL-6)\ub97c \uc9c4\ub2e8 \ub3c4\uad6c \uc138\ud2b8\uc5d0 \ucd94\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc911\uc99d COVID-19\uc758 \uc870\uae30 \uc608\uce21 \uc9c0\ud45c\ub85c\uc11c IL-6\ub294 \uc27d\uac8c \ucc44\ucde8\ud560 \uc218 \uc788\ub294 \uc0dd\ubb3c\ud559\uc801 \uc2dc\ub8cc(\ud608\uccad \ub610\ub294 \ud608\uc7a5)\uc5d0\uc11c \uac80\ucd9c\ud560 \uc218 \uc788\uace0, \uc798 \uac80\uc99d\ub41c \uc2e0\uc18d\ud55c \ubd84\uc11d \uc2dc\uc2a4\ud15c\uc744 \ud1b5\ud574 \uce21\uc815\ud560 \uc218 \uc788\uae30 \ub54c\ubb38\uc5d0 \uc774\uc0c1\uc801\uc778 \uc608\ud6c4 \ubc14\uc774\uc624\ub9c8\ucee4\uc785\ub2c8\ub2e4. \uc810\uc810 \ub354 \ub9ce\uc740 \uc5f0\uad6c \uacb0\uacfc\uac00 IL-6\uac00 \uc911\uc99d COVID-19 \uad00\ub9ac\uc758 \ud544\uc218\uc801\uc778 […]<\/p>\n","protected":false},"author":1,"featured_media":84784,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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