{"id":146485,"date":"2024-02-21T09:10:17","date_gmt":"2024-02-21T09:10:17","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%ed%8c%a8%ed%98%88%ec%a6%9d-%ea%b4%80%eb%a6%ac%ec%97%90%ec%84%9c-%ec%83%9d%ec%b2%b4%ed%91%9c%ec%a7%80%ec%9e%90%ec%9d%98-%ec%97%ad%ed%95%a0\/"},"modified":"2026-02-16T07:53:15","modified_gmt":"2026-02-16T07:53:15","slug":"the-role-of-biomarkers-in-management-of-sepsis","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ko\/disease-area\/sepsis\/the-role-of-biomarkers-in-management-of-sepsis\/","title":{"rendered":"\ud328\ud608\uc99d \uad00\ub9ac\uc5d0\uc11c \uc0dd\uccb4\ud45c\uc9c0\uc790\uc758 \uc5ed\ud560"},"content":{"rendered":"

\ud328\ud608\uc99d\uacfc \ud328\ud608\uc131 \uc1fc\ud06c\uc5d0 \ub300\ud55c \uc138 \ubc88\uc9f8 \uad6d\uc81c \ud569\uc758 \uc815\uc758 (Sepsis-3)<\/a>\ub294 \ud328\ud608\uc99d\uc744 ‘\uac10\uc5fc\uc5d0 \ub300\ud55c \uc870\uc808\uc7a5\uc560\uac00 \ubc1c\uc0dd\ub41c \uc219\uc8fc \ubc18\uc751\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c \uce58\uba85\uc801\uc778 \uc7a5\uae30 \uae30\ub2a5 \uc7a5\uc560’\ub85c \uc815\uc758\ud569\ub2c8\ub2e4.<\/p>\n

\ud328\ud608\uc131 \uc1fc\ud06c\ub294 ‘\uadfc\ubcf8\uc801\uc778 \uc21c\ud658, \uc138\ud3ec \ubc0f \ub300\uc0ac \uc774\uc0c1\uc774 \ud328\ud608\uc99d \ub2e8\ub3c5\ubcf4\ub2e4 \uc0ac\ub9dd \uc704\ud5d8\uc774 \ub354 \ud070 \ud328\ud608\uc99d\uc758 \ud558\uc704 \uc9d1\ud569’\ub85c \uc815\uc758\ub429\ub2c8\ub2e4. \ud328\ud608\uc99d\uc740 \ub2e8\uc77c \uc9c4\ub2e8 \uac80\uc0ac\uac00 \uc5c6\uae30 \ub54c\ubb38\uc5d0 \uc784\uc0c1 \uc9c4\ub2e8\uc785\ub2c8\ub2e4. \uc0dd\ub9ac\ud559\uc801 \uc774\uc0c1\uacfc \uac80\uc0ac\uc2e4 \uc774\uc0c1\uc774 \ubaa8\ub450 \uc874\uc7ac\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud328\ud608\uc99d-3\uc740 ‘\uc911\uc99d \ud328\ud608\uc99d’\uc774\ub77c\ub294 \uc6a9\uc5b4\ub97c \uc5c6\uc560\uace0, \ub300\uc2e0 \ud328\ud608\uc99d \ud658\uc790\uc758 \uc870\uae30 \uc778\uc2dd\uacfc \ubcf4\ub2e4 \uc2dc\uae30 \uc801\uc808\ud55c \uad00\ub9ac\ub97c \uc6a9\uc774\ud558\uac8c \ud558\uae30 \uc704\ud55c \ubaa9\uc801\uc73c\ub85c ‘\ud328\ud608\uc131 \uc1fc\ud06c’\uc640 ‘\ud328\ud608\uc99d’\uc744 \uc815\uc758\ud558\uace0 \uacc4\uce35\ud654\ud588\uc2b5\ub2c8\ub2e4. \ud328\ud608\uc99d\uc740 \uc911\uc99d\ub3c4\uc758 \uc2a4\ud399\ud2b8\ub7fc\uc73c\ub85c \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \uc9c4\ub2e8\uc5d0 \ub300\ud55c \ubd88\ud655\uc2e4\uc131\uc774 \uc788\uc744 \uc218 \uc788\uc9c0\ub9cc, \ud328\ud608\uc99d\uc744 \uc553\ub294 \uc784\uc758\uc758 \ud658\uc790\uc5d0\uc11c \uc2e0\uc18d\ud558\uace0 \uc2ec\uac01\ud55c \uc545\ud654\uc758 \uac00\ub2a5\uc131\uc73c\ub85c \uc778\ud574 \ud328\ud608\uc99d\uc774 \uac00\ub2a5\ud560 \ub54c\ub9c8\ub2e4 \uac1c\uc785\uc744 \ud544\uc694\ub85c \ud569\ub2c8\ub2e4 [1].<\/p>\n

Global Burden of Disease \uc5f0\uad6c<\/a>\ub294 195\uac1c \uad6d\uac00 \ubc0f \uc9c0\uc5ed\uc758 1\uc5b5 900\ub9cc \uac74\uc758 \uc0ac\ub9dd \uae30\ub85d \ubc0f 860\ub9cc \uac74\uc758 \ubcd1\uc6d0 \uae30\ub85d \ub370\uc774\ud130\ub97c \uc0ac\uc6a9\ud558\uc5ec \uc804 \uc138\uacc4\uc758 \ud328\ud608\uc99d \ubd80\ub2f4\uc744 \ucd94\uc815\ud588\uc2b5\ub2c8\ub2e4. 2017\ub144\uc5d0 4,900\ub9cc \uac74\uc758 \ud328\ud608\uc99d \uc0ac\ub840\uc640 1,100\ub9cc \uac74\uc758 \uc0ac\ub9dd\uc774 \uc788\uc5c8\ub2e4\ub294 \uac83\uc774 \ubc1d\ud600\uc84c\ub294\ub370 \uc774\ub294 \uc774\uc804 \ucd94\uc815\uce58\uc758 \ub450 \ubc30\uc774\uba70 \ud328\ud608\uc99d\uacfc \uad00\ub828\ub41c \uc804 \uc138\uacc4 \uc0ac\ub9dd\uc758 1\/5\uc785\ub2c8\ub2e4. \ub300\ubd80\ubd84 \uc608\ubc29\ud560 \uc218 \uc788\ub294 \uc0c1\ud0dc\uc5d0\uc11c \ub9ce\uc740 \uc0ac\ub78c\ub4e4\uc774 \ubaa9\uc228\uc744 \uc783\uc5b4 \uc6b0\ub824\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud638\uc8fc\uc758 \ud328\ud608\uc99d \ubd80\ub2f4\uc5d0 \ub300\ud55c \uc774\uc804\uc758 \ucd94\uc815\uce58\ub294 \uc8fc\ub85c \uc911\ud658\uc790\uc2e4\uc5d0\uc11c \uce58\ub8cc\ubc1b\uc740 \uac83\uc73c\ub85c, \uc0ac\ub840 \uc218\ub294 18,000\uac74, \uc0ac\ub9dd\uc740 5,000\uac74\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 Global Burden of Disease \uc5f0\uad6c \ucd94\uc815\uce58\ub294 \uc774\uc81c \ubcd1\uc6d0 \uc678\ubd80\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \ud328\ud608\uc99d\uc744 \ud3ec\ud568\ud558\uc5ec \ubb38\uc81c\uc758 \uaddc\ubaa8\uc5d0 \ub300\ud55c \ubcf4\ub2e4 \uc815\ud655\ud55c \uadf8\ub9bc\uc744 \uc81c\uacf5\ud558\uc5ec \ud638\uc8fc \uc0ac\ub840 \uc218\ub97c 55,000\uac74\uc73c\ub85c, \uc0ac\ub9dd\uc790\ub97c 8,700\uba85\uc73c\ub85c \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n

\ud328\ud608\uc99d\uc740 \uac10\uc5fc\uc5d0 \ub300\ud55c \uc2e0\uccb4\uc758 \ubc18\uc751\uc774 \uc790\uc2e0\uc758 \uc870\uc9c1\uacfc \uae30\uad00\uc744 \uc190\uc0c1\uc2dc\ud0ac \ub54c \ubc1c\uc0dd\ud558\ub294 \uc2dc\uac04\uc774 \uc911\uc694\ud55c \uc758\ub8cc \uc751\uae09 \uc0c1\ud669\uc785\ub2c8\ub2e4. \uc870\uae30\uc5d0 \uc778\uc9c0\ud558\uc9c0 \ubabb\ud558\uace0 \uc2e0\uc18d\ud558\uac8c \uce58\ub8cc\ud558\uc9c0 \uc54a\uc73c\uba74 \uc1fc\ud06c, \ub2e4\uae30\uad00 \ubd80\uc804, \uc0ac\ub9dd\uc5d0 \uc774\ub97c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud328\ud608\uc99d\uc740 \ub2e4\uc591\ud55c \uc784\uc0c1 \uc804\ubb38 \ubd84\uc57c\uc5d0 \uac78\uccd0 \ubaa8\ub4e0 \uc5f0\ub839\ub300\uc640 \ud658\uc790\uc758 \uc0ac\ub78c\ub4e4, \ud2b9\ud788 \ub9e4\uc6b0 \uc80a\uc740 \uc0ac\ub78c\ub4e4, \ub9e4\uc6b0 \ub098\uc774\ub4e0 \uc0ac\ub78c\ub4e4, \uc6d0\uc8fc\ubbfc \ubc0f \ud1a0\ub808\uc2a4 \ud574\ud611 \uc12c\uc8fc\ubbfc\uc5d0\uac8c \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uadf8\ub7ec\ub098 2016\ub144 \uc124\ubb38\uc870\uc0ac\uc5d0 \ub530\ub974\uba74 \ud638\uc8fc\uc778\uc758 60%\uac00 \ud328\ud608\uc99d\uc5d0 \ub300\ud574 \ub4e4\uc5b4 \ubcf4\uc9c0 \ubabb\ud588\uace0 14%\ub9cc\uc774 \uc99d\uc0c1 \uc911 \ud558\ub098\ub97c \ub2f5\ud560 \uc218\uc788\uc5c8\uc2b5\ub2c8\ub2e4. \ud328\ud608\uc99d\uc73c\ub85c \uc778\ud55c \uc2ec\uac01\ud55c \uc0ac\ub9dd\uacfc \uc7a5\uc560\ub97c \ud574\uacb0\ud558\uae30 \uc704\ud574 \ubcd1\uc6d0 \uc804 \ubc0f \ubcd1\uc6d0 \ub0b4 \uc778\uc2dd \ubc0f \uce58\ub8cc\ub97c \ub2e4\ub8e8\ub294 \uc870\uc815\ub41c \uad6d\uac00\uc801 \uc811\uadfc \ubc29\uc2dd\uc774 \ud544\uc694\ud569\ub2c8\ub2e4 [2].<\/p>\n

\ud328\ud608\uc99d \uad00\ub9ac\uc5d0\uc11c \ud504\ub85c\uce7c\uc2dc\ud1a0\ub2cc\uc758 \uc5ed\ud560<\/h2>\n

\uc911\uc99d \uac10\uc5fc \ubc0f \ud328\ud608\uc99d\uc774 \uc788\ub294 \uc704\ub3c5\ud55c \ud658\uc790\uc758 \uc784\uc0c1 \uad00\ub9ac\ub294 \uc9c4\ub2e8 \ubc0f \uce58\ub8cc \uacb0\uc815\uae4c\uc9c0\uc758 \uc2dc\uac04\uc744 \ub2e8\ucd95\ud568\uc73c\ub85c\uc368 \uac1c\uc120\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4(\uc989, \ubc15\ud14c\ub9ac\uc544 \ub300 \ubc14\uc774\ub7ec\uc2a4 \ub300 \uc9c4\uade0 \uac10\uc5fc \ubc0f \ube44\uac10\uc5fc\uc131 \ubcd1\uc778 \uac04\uc758 \uad6c\ubcc4). \ub610\ud55c, \uc870\uae30 \uc704\ud5d8 \uacc4\uce35\ud654 \ubc0f \uc608\ud6c4 \uc815\ubcf4 \uc81c\uacf5\uc744 \ud1b5\ud574 \uce58\ub8cc \ubd80\uc704 \uacb0\uc815(\uc608: \uc870\uae30 \ud1f4\uc6d0 \ub610\ub294 \uce58\ub8cc \ud655\ub300)\uc744 \uac1c\uc120\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ubc18\ubcf5\uc801\uc73c\ub85c \uce21\uc815\ub41c \uc0dd\uccb4\ud45c\uc9c0\uc790\ub294 \ub610\ud55c \ud658\uc790\uc758 \uac1c\ubcc4 \uc694\uad6c\uc5d0 \ub9de\uac8c \uce58\ub8cc\ub97c \ubaa8\ub2c8\ud130\ub9c1\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4(\ud56d\uc0dd\uc81c \uad00\ub9ac). \uc774\ub7f0 \ub9e5\ub77d\uc5d0\uc11c, \uc219\uc8fc \ubc18\uc751 \ubc0f \ud608\uc561 \uac10\uc5fc \ub9c8\ucee4 \ud504\ub85c\uce7c\uc2dc\ud1a0\ub2cc(PCT)\uc758 \uc774\uc6a9\uc740 \ub9ce\uc740 \uc8fc\ubaa9\uc744 \ubc1b\uc558\uace0, \uadf8\ub9ac\uace0 \ud638\ud761\uae30 \uac10\uc5fc \ubc0f \ud328\ud608\uc99d\uc744 \uc553\ub294 \ud658\uc790\uc5d0\uc11c \ud56d\uade0\uc81c \uc694\ubc95\uc758 \uc548\ub0b4\ub97c \uc704\ud574 \uc774\ubbf8 \uc2b9\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4. PCT\ub294 \uac74\uac15\ud55c \uac1c\uc778\uc5d0\uc11c \uac80\ucd9c\ub418\uc9c0 \uc54a\ub294 \uce7c\uc2dc\ud1a0\ub2cc\uc758 \uc120\uad6c\uc790 \ud638\ub974\ubaac\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 PCT\uc758 \uc0dd\uc0b0\uc740 \ubc15\ud14c\ub9ac\uc544 \uac10\uc5fc\uc5d0 \ubc18\uc751\ud558\uc5ec \uc0c1\ud5a5 \uc870\uc808\ub418\uba70 \ud68c\ubcf5\ub418\ub294 \ub3d9\uc548 \ube60\ub974\uac8c \uac10\uc18c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c PCT\ub294 \uc784\uc0c1 \ubc0f \uc9c4\ub2e8 \ub9e4\uac1c\ubcc0\uc218\ub97c \ubcf4\uc644\ud560 \uc218 \uc788\ub294 \uc911\uc694\ud55c \ucd94\uac00 \uc815\ubcf4\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc774\uac83\uc740 \ucc28\ub840\ub85c \uac10\uc5fc \ub610\ub294 \ud328\ud608\uc99d\uc774 \uc758\uc2ec\ub418\ub294 \ud658\uc790\uc758 \uce58\ub8cc\uc5d0 \uad00\ud55c \uacb0\uc815\uc5d0 \ub192\uc740 \uc601\ud5a5\uc744 \ubbf8\uce60 \ubfd0\ub9cc \uc544\ub2c8\ub77c \ud56d\uc0dd\uc81c \uce58\ub8cc \uacfc\uc815\uc758 \uae30\uac04\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. PCT\uc758 \uc0ac\uc6a9\uc740 \ud328\ud608\uc99d \uad00\ub9ac\uc5d0\uc11c \uc9c4\ud654\ud558\uace0 \uc788\uc73c\uba70 \uc5ec\ub7ec \uc911\uc7ac \uc5f0\uad6c\uc640 \uccb4\uacc4\uc801\uc778 \uac80\ud1a0\ub294 PCT \uc720\ub3c4 \uc804\ub7b5\uc774 \ud56d\uc0dd\uc81c \uc0ac\uc6a9 \ubc0f \uac74\uac15 \uacb0\uacfc\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \ubd84\uc11d\ud558\uace0 \uc694\uc57d\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud328\ud608\uc99d \ud658\uacbd\uc5d0\uc11c PCT\uc758 \ucd5c\uc801 \uc0ac\uc6a9\uc5d0 \ub300\ud55c \ubcf4\ud3b8\uc801\uc778 \ud569\uc758\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uac74\uac15\ud55c \uac1c\uccb4\uc5d0\uc11c, \ud608\uccad PCT\ub294 \uac80\ucd9c\uac00\ub2a5\ud558\uc9c0 \uc54a\uc740\ub370, \uadf8 \uc774\uc720\ub294 \ub2e8\ubc31\uc9c8\uc774 \uc804\uc2e0 \uc5fc\uc99d\uc758 \ubd80\uc7ac\uc5d0\uc11c \ud608\uc561\uc73c\ub85c \ubc29\ucd9c\ub418\uc9c0 \uc54a\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ubc15\ud14c\ub9ac\uc544 \uac10\uc5fc\uc73c\ub85c \uc778\ud55c \ud328\ud608\uc99d\uc758 \uacbd\uc6b0 PCT \ud569\uc131\uc740 \uac70\uc758 \ubaa8\ub4e0 \uc870\uc9c1\uc5d0\uc11c \uc720\ub3c4\ub418\ubbc0\ub85c \ud608\uc561\uc5d0\uc11c \uac80\ucd9c \uac00\ub2a5\ud569\ub2c8\ub2e4. PCT \ud569\uc131\uc740 \uc138\uade0 \ub3c5\uc18c, \uc608\ucee8\ub300 \ub0b4\ub3c5\uc18c \ubc0f \uc0ac\uc774\ud1a0\ud0a8\uc5d0 \uc758\ud574 \ucd09\ubc1c\ub418\ub294\ub370, \uc608\ub97c \ub4e4\uba74, \uc778\ud130\ub958\ud0a8(IL)-1\ubca0\ud0c0, \uc778\ud130\ub958\ud0a8-6 \ubc0f \uc885\uc591 \uad34\uc0ac \uc778\uc790(TNF)-\uc54c\ud30c\uac00 \uc788\uc2b5\ub2c8\ub2e4. TNF-\uc54c\ud30c\uc758 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud558\ub294 \ubc14\uc774\ub7ec\uc2a4 \uac10\uc5fc \uc911\uc5d0 \ubc29\ucd9c\ub418\ub294 \uc0ac\uc774\ud1a0\uce74\uc778\uc73c\ub85c \uc778\ud574 \ub300\ubd80\ubd84\uc758 \ubc14\uc774\ub7ec\uc2a4 \uac10\uc5fc\uc5d0\uc11c\ub294 PCT \ud569\uc131\uc774 \uc720\ub3c4\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub354\uc6b1\uc774, PCT\ub294 \uc0dd\ubb3c\ud559\uc801 \ubc94\uc704\uac00 \ub113\uace0, \ubc15\ud14c\ub9ac\uc544 \uc790\uadf9 \ud6c4 \uc720\ub3c4\uae4c\uc9c0\uc758 \uc2dc\uac04\uc774 \uc9e7\uace0 \ubc18\uac10\uae30\uac00 \uae41\ub2c8\ub2e4. \ub530\ub77c\uc11c PCT\ub294 \ube60\ub974\uac8c \uc774\uc6a9 \uac00\ub2a5\ud55c \uacb0\uacfc\ub85c \ubc15\ud14c\ub9ac\uc544\uc640 \ubc14\uc774\ub7ec\uc2a4 \uc5fc\uc99d\uc744 \uad6c\ubcc4\ud558\ub294 \ub370 \uc88b\uc740 \ucc28\ubcc4\uc801 \ud2b9\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. PCT \uc790\uccb4\ub294 \ud2b9\uc815 \ubcd1\uc6d0\uccb4\ub97c \ubd84\ub9ac\ud558\uac70\ub098 \uac80\ucd9c\ud560 \uc218 \uc5c6\uc9c0\ub9cc PCT \uc218\uc900\uc740 \uc2ec\uac01\ud55c \ubc15\ud14c\ub9ac\uc544 \uac10\uc5fc\uc758 \uac00\ub2a5\uc131\uc744 \ucd94\uc815\ud558\ub294 \ub370 \uc720\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc218\uc2ed\ub144 \uac04\uc758 \uc5f0\uad6c \ub178\ub825\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0, \uc774\uc6a9 \uac00\ub2a5\ud55c \ud328\ud608\uc99d \ud2b9\uc774\uc801 \uce58\ub8cc \uc635\uc158\uc740 \uc5ec\uc804\ud788 \uc5c6\uc2b5\ub2c8\ub2e4. \uc131\uacf5\uc801\uc778 \uce58\ub8cc\uc640 \uae0d\uc815\uc801\uc778 \uacb0\uacfc\uc5d0 \uc911\uc694\ud55c \uac83\uc740 \uc870\uae30 \uc9c4\ub2e8\uacfc \ube44\uac10\uc5fc\uc131 \uc6d0\uc778\uacfc\uc758 \uad6c\ubcc4\uc774\uba70, \ud56d\uade0 \uc694\ubc95\uacfc \uc218\uc561 \uc18c\uc0dd\uc73c\ub85c \uc2e0\uc18d\ud558\uac8c \uc774\ub8e8\uc5b4\uc9d1\ub2c8\ub2e4. \ud558\uc9c0\ub9cc, \ud655\uc815\uc801\uc774\uac70\ub098 \uc758\uc2ec\ub418\ub294 \ud328\ud608\uc99d\uc5d0 \ub300\ud55c \uc784\uc0c1\uc801 \uc9d5\ud6c4\uac00 \uc774\uc9c8\uc801\uc774\uace0 \uc885\uc885 \ubaa8\ud638\ud560 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\ub85c \uc778\ud574, \uc774\ub97c \uc9c4\ub2e8\ud558\uace0 \uce58\ub8cc\ud558\uae30\ub294 \uc5ec\uc804\ud788 \uc5b4\ub835\uc2b5\ub2c8\ub2e4. \ud604\uc7ac\uae4c\uc9c0 \ud608\ub958 \uac10\uc5fc\uc73c\ub85c \uc778\ud55c \ud328\ud608\uc99d\uc758 \uac80\ucd9c\uc744 \uc704\ud55c \ucd5c\uc801\uc758 \ud45c\uc900\uc740 \uc874\uc7ac\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc784\uc0c1\uc801\uc73c\ub85c \uc758\uc2ec\ub418\ub294 \uac10\uc5fc \ub610\ub294 \ud328\ud608\uc99d\uc774 \uc788\ub294 \ud658\uc790\uc5d0\uc11c \ud608\uc561 \ubc30\uc591 \ubc0f \uc5fc\uc99d\uc131 \ud608\uc561 \ub9c8\ucee4 C-\ubc18\uc751\uc131 \ub2e8\ubc31\uc9c8(CRP), \ubc31\ud608\uad6c \uc218(WBC)\uc640 \uac19\uc740 \uae30\uc874 \uc9c4\ub2e8 \uc811\uadfc\ubc95\uc758 \uc0ac\uc6a9\uc740 \uc77c\ubd80 \uc81c\ud55c\uc5d0 \uc758\ud574 \uc81c\ud55c\ub429\ub2c8\ub2e4. \ubcd1\uc6d0\uccb4\uc758 \uc2dd\ubcc4\uc744 \uc704\ud55c \ud608\uc561 \ubc30\uc591\uc758 \uc0ac\uc6a9\uc740 \ubbf8\uc0dd\ubb3c\uc758 \uc720\ud615\uacfc \ud56d\uc0dd\uc81c \uce58\ub8cc\uc5d0 \ub300\ud55c \ubbfc\uac10\ub3c4\uc5d0 \ub300\ud55c \uc815\ubcf4\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ubd84\uc11d\ub41c \ubc30\uc591\uc561\uc758 \uc77c\ubd80\ub9cc\uc774 \uc591\uc131\uc73c\ub85c \ub098\ud0c0\ub098\uace0 \uac00\uc815\ub41c \uc804\uc2e0 \uac10\uc5fc\uc744 \uac00\uc9c4 \ud658\uc790\uc758 \uc57d 40~90%\uc5d0\uc11c \uacb0\uacfc\ub294 \uc131\uc7a5\ud558\ub294 \ubcd1\uc6d0\uccb4\uac00 \uc5c6\ub294 \uc74c\uc131 \ud608\uc561 \ubc30\uc591\uc785\ub2c8\ub2e4. \ub354\uc6b1\uc774, \uacb0\uacfc\uae4c\uc9c0\uc758 \uae34 \uc2dc\uac04\uc740 \ucd08\uae30 \uce58\ub8cc \uc758\uc0ac \uacb0\uc815\uc744 \uc81c\ud55c\ud558\uace0 \uc624\uc5fc\uc740 \uc5bb\uc740 \uacb0\uacfc\uc758 \ucc28\uc120\uc758 \ud2b9\uc774\uc131\uc744 \ucd08\ub798\ud569\ub2c8\ub2e4. \uc9c4\ub2e8 \uac80\uc0ac\ub97c \uac1c\uc120\ud558\uae30 \uc704\ud574\uc11c\ub294 \ucd94\uac00 \uac80\uc0ac\uac00 \uc801\uc808\ud558\uba70, \uc774\ub294 \uc870\uae30\uc5d0 \uc2e0\ub8b0\ud560 \uc218 \uc788\ub294 \uc9c4\ub2e8\uc744 \uc6a9\uc774\ud558\uac8c \ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4 [3].<\/p>\n

IL-6 \ubc0f \uc2e0\uc0dd\uc544 \ud328\ud608\uc99d\uc5d0\uc11c\uc758 \uc5ed\ud560<\/h2>\n

\uc2e0\uc0dd\uc544 \ud328\ud608\uc99d\uc740 \uc804 \uc138\uacc4\uc801\uc73c\ub85c \ubaa8\ub4e0 \uc7a5\uc560 \ubcf4\uc815 \uc218\uba85\uc758 0.97%\ub97c \ucc28\uc9c0\ud558\uba70 \uacb0\uc7a5\uc554\uacfc \uc9c1\uc7a5\uc554, \ucc9c\uc2dd \ub610\ub294 \uc720\ubc29\uc554\uc5d0 \ube44\ud574 \ub354 \ub192\uc740 \ube44\uc728\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc2e0\uc0dd\uc544 \ud328\ud608\uc99d\uc740 \uc0ac\ub9dd\ub960\uc774 11~19%2\ub85c \ub192\uc73c\uba70, \uc18c\uc544\uae30 \ucd08\uae30\uc758 \ubd88\ub7c9\ud55c \uc2e0\uacbd\ubc1c\ub2ec \ubc0f \uc131\uc7a5 \uacb0\uacfc\ubfd0\ub9cc \uc544\ub2c8\ub77c \ub1cc \uc190\uc0c1\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc774\uc0c1 \uacb0\uacfc\ub294 \uc870\uae30 \ubc1c\uacac\uacfc \uc2e0\uc18d\ud55c \uac1c\uc785\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \ud328\ud608\uc99d\uc740 \uac10\uc5fc\uc5d0 \ub300\ud55c \uc804\uc2e0 \uc5fc\uc99d \ubc18\uc751\uc774\uae30 \ub54c\ubb38\uc5d0 \ud608\uc561\uc5d0\uc11c \ubc15\ud14c\ub9ac\uc544\ub97c \ubd84\ub9ac\ud558\ub294 \uac83\uc774 \ucd5c\uc801 \ud45c\uc900\uc73c\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4. \ub9e4\uc6b0 \ub0ae\uc740 \ucd9c\uc0dd \uc2dc \uccb4\uc911\uc758 \uc601\uc544(VLBW \uc601\uc544, \ucd9c\uc0dd \uccb4\uc911 < 1500gm)\uc5d0\uc11c \uc5bb\uc744 \uc218 \uc788\ub294 \uc57d 0.5~1ml\uc758 \ub0ae\uc740 \ud608\uc561\ub7c9, \ub0ae\uc740 \uc218\uc900\uc758 \uade0\ud608\uc99d\uc758 \ub192\uc740 \ubc31\ubd84\uc728 \ubc0f \uc591\uc131 \ud608\uc561 \ubc30\uc591\uae4c\uc9c0\uc758 \uae34 \uae30\uac04\uc73c\ub85c \uc778\ud574, \ud504\ub85c\uce7c\uc2dc\ud1a0\ub2cc, \uc9c0\uc9c8\ub2e4\ub2f9\ub958 \uacb0\ud569 \ub2e8\ubc31\uc9c8, \ud504\ub9ac\uc149\uc2e0 \ubc0f \uc778\ud130\ub8e8\ud0a8-6\uc744 \ud3ec\ud568\ud55c \uc2e0\uc0dd\uc544 \ud328\ud608\uc99d \uc9c4\ub2e8\uc758 \uc815\ud655\uc131\uc5d0 \ub300\ud574 \uc5ec\ub7ec \ud30c\ub77c\ubbf8\ud130\uac00 \uac80\uc0ac\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

IL-6\uc740 \uba74\uc5ed \ubc18\uc751, \uc870\ud608 \ubc0f \uae09\uc131\uae30 \ubc18\uc751\uc5d0 \ucc38\uc5ec\ud558\ub294 \ub2e4\uae30\ub2a5 \uc0ac\uc774\ud1a0\uce74\uc778\uc785\ub2c8\ub2e4. \uac10\uc5fc\uc5d0 \ub300\ud55c \ubc18\uc751\uc73c\ub85c, IL-6\uc740 IgM, IgG \ubc0f IgA\uc758 \uc0dd\uc0b0\ubfd0\ub9cc \uc544\ub2c8\ub77c \ubcf4\uc870 T \uc138\ud3ec\uc758 \uc99d\uc2dd\uc744 \uc99d\uac15\ud558\uace0, \uadf8\ub9ac\uace0 \ub530\ub77c\uc11c \uc219\uc8fc \ubc29\uc5b4 \uae30\uc804\uc5d0\uc11c \uacb0\uc815\uc801\uc778 \uc5ed\ud560\uc744 \uc218\ud589\ud569\ub2c8\ub2e4. \ubc15\ud14c\ub9ac\uc544 \ub0b4\ub3c5\uc18c\uc5d0 \ub178\ucd9c\ub41c \ud6c4 IL-6 \ub18d\ub3c4\ub294 C-\ubc18\uc751\uc131 \ub2e8\ubc31\uc9c8(CRP)\uc744 \ud3ec\ud568\ud55c \uae09\uc131\uae30 \ubc18\uc751\ubb3c \uc804\uc5d0 \uc0c1\uc2b9\ud569\ub2c8\ub2e4. IL-6\uc740 \uc81c\ub300\ud608 \ub610\ub294 \ud608\uccad\uc5d0\uc11c \uacb0\uc815\ub418\uc5b4 \uc0c1\uc774\ud55c \uc9c4\ub2e8 \uc815\ud655\ub3c4\ub97c \uc0b0\ucd9c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\ub300\ud608 IL-6\ub294 \uc870\uae30 \ubc1c\ubcd1 \ud328\ud608\uc99d\uc5d0 \ub300\ud574 87~100%\uc758 \ubbfc\uac10\ub3c4\ub97c \ubcf4\uc785\ub2c8\ub2e4. \ud608\uccad IL-6\uc740 \uc870\uae30\ubc1c\ubcd1 \ud328\ud608\uc99d \uc9c4\ub2e8\uc5d0 75~85%\uc758 \ubbfc\uac10\ub3c4\uc640 72.8~88%\uc758 \ud2b9\uc774\ub3c4\ub97c \uac00\uc9c0\uba70, \ud6c4\uae30\ubc1c\ubcd1 \ud328\ud608\uc99d\uc5d0 80~93.8%\uc758 \ubbfc\uac10\ub3c4\uc640 80~96%\uc758 \ud2b9\uc774\ub3c4\ub97c \uac00\uc838 CRP\ub97c \ub2a5\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud608\uccad IL-6 \ub18d\ub3c4\ub294 \ud56d\uc0dd\uc81c \uce58\ub8cc \uc911\uc5d0 \uac80\ucd9c \ubd88\uac00\ub2a5\ud55c \uac12\uc73c\ub85c \ube60\ub974\uac8c \ub5a8\uc5b4\uc9d1\ub2c8\ub2e4. IL-6\uc740 \ub192\uc740 \ubbfc\uac10\ub3c4 \ubc0f \uc74c\uc131 \uc608\uce21\uac12\ub85c \uc778\ud574 \ub192\uc740 \ud2b9\uc774\uc801 CRP\uc640 \ubcd1\uc6a9\uc73c\ub85c \uc2e0\uc0dd\uc544 \ud328\ud608\uc99d\uc744 \uc9c4\ub2e8\ud558\ub294 \ub370 \uc801\ud569\ud55c \ud6c4\ubcf4\uc785\ub2c8\ub2e4.<\/p>\n

\"\"<\/p>\n

\uadf8\ub9bc1: \ud328\ud608\uc99d\uc5d0\uc11c \uc778\ud130\ub958\ud0a8-6\uacfc C-\ubc18\uc751\uc131 \ub2e8\ubc31\uc9c8 \uadf8\ub9ac\uace0 \uc2dc\uac04\uc758 \ucd94\uc774\uc5d0\uc11c \uc774\ub4e4\uc758 \ubc1c\ub2ec. \uc0dd\ud6c4 1\uc77c(a) \ubc0f \uc0dd\ud6c4 7\uc77c(b) \ud6c4 \ubc30\uc591 \ud655\uc778\ub41c \ud328\ud608\uc99d\uc5d0\uc11c \ud608\uccad \uc778\ud130\ub958\ud0a8-6 \ubc0f C-\ubc18\uc751\uc131 \ub2e8\ubc31\uc9c8(CRP).<\/em><\/p>\n

\uadf8\ub9bc 1\uc5d0\uc11c \ubcf4\ub294 \ubc14\uc640 \uac19\uc774, DOL 1(\uc0dd\ud6c4 1\uc77c)\uc5d0\uc11c \ubc30\uc591\uc774 \ud655\uc778\ub41c \ud328\ud608\uc99d\uc758 \uacbd\uc6b0 \ud608\uccad IL-6\uc774 \ud06c\uac8c \uc0c1\uc2b9\ud558\uae30 \uc2dc\uc791\ud558\ub294 \ubc18\uba74, CRP\ub294 \ucd5c\uace0\uc810\uc5d0 \ub3c4\ub2ec\ud558\ub294 \ub370 48\uc2dc\uac04\uc774 \uac78\ub9bd\ub2c8\ub2e4. \ud608\uccad IL-6\uc758 \ub192\uc740 \uc815\ud655\ub3c4\ub97c \uae30\ubc18\uc73c\ub85c, \uc6b0\ub9ac\ub294 DOL 1\uc5d0\uc11c \uacb0\uc815\ub41c IL-6\uc774 \uc120\ucc9c\uc131 \ud328\ud608\uc99d\uc758 \uc9c4\ub2e8\uc5d0 \ub9e4\uc6b0 \ub3c4\uc6c0\uc774 \ub41c\ub2e4\uace0 \uacb0\ub860\ub0b4\ub9bd\ub2c8\ub2e4. \uadf8\ub9bc 1\uc5d0\ub3c4 \ud45c\uc2dc\ub41c \ubc14\uc640 \uac19\uc774, \ud608\uccad IL-6\uc740 DOL 7 \uc774\ud6c4 \ubc30\uc591 \ud655\uc778\ub41c \ud328\ud608\uc99d \uc5d0\ud53c\uc18c\ub4dc\uc5d0\uc11c CRP 24-48\uc2dc\uac04 \uc804\uc5d0 \uc99d\uac00\ud569\ub2c8\ub2e4.\uc774\ub294 \ud608\uccad IL-6\uc744, \uc0b6\uc758 \uccab \uc8fc \ud6c4 \ud328\ud608\uc99d\uc758 \uc0ac\ub840\uc5d0\uc11c \uc0c1\uc2b9\ud558\ub294 \uac00\uc7a5 \uc815\ud655\ud558\uace0 \uccab \ubc88\uc9f8 \uac80\uc0ac\uc2e4 \ud30c\ub77c\ubbf8\ud130\ub85c \ub9cc\ub4ed\ub2c8\ub2e4. Tzialla et al.\uc740 \uae09\uc131\uae30 \ubc18\uc751\ubb3c \uc804\uc5d0\ub3c4 \uc0ac\uc774\ud1a0\uce74\uc778 \uc218\uc900\uc774 \ube60\ub974\uac8c \ubcc0\ud558\ub294 \uac83\uc73c\ub85c \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub192\uc740 \uc815\ud655\ub3c4, \ud2b9\ud788 \ud608\uccad IL-6\uc758 \ub9e4\uc6b0 \ub192\uc740 \uc74c\uc131 \uc608\uce21\uac12\uc5d0 \uadfc\uac70\ud558\uc5ec, \uc6b0\ub9ac\ub294 \ud608\uccad IL-6\uc774 \uc2e0\uc0dd\uc544 \ubc0f \ubbf8\uc219\uc544\uc758 \ud328\ud608\uc99d \uc9c4\ub2e8\uc5d0 \ub9e4\uc6b0 \ub3c4\uc6c0\uc774 \ub41c\ub2e4\uace0 \uacb0\ub860\ub0b4\ub838\uc2b5\ub2c8\ub2e4. \ub610\ud55c, IL-6\uc740 \ud6a8\uacfc\uc801\uc778 \ud56d\uc0dd\uc81c \uc694\ubc95\uc758 \uac1c\uc2dc \ud6c4 \ube60\ub974\uac8c \uac10\uc18c\ud558\uc5ec, \ud56d\uc0dd\uc81c \uc694\ubc95\uc758 \uc2e0\uc18d\ud55c \ubaa8\ub2c8\ud130\ub9c1 \ubc0f \uce58\ub8cc\uc758 \uc801\uc2dc \uc99d\uac00 \ub610\ub294 \uac10\uc18c\ub97c \uac00\ub2a5\ud558\uac8c \ud569\ub2c8\ub2e4 [4].<\/p>\n

\uacb0\ub860<\/h2>\n

\ud328\ud608\uc99d\uc740 \uc0dd\uba85\uc744 \uc704\ud611\ud558\ub294 \uc9c8\ubcd1\uc774\uba70 ICU \uc785\uc6d0 \ud658\uc790\uc758 \uac00\uc7a5 \ud754\ud55c \uc6d0\uc778 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4. \ud328\ud608\uc99d\uc758 \uc0ac\ub9dd\ub960\uc744 \ub0ae\ucd94\uae30 \uc704\ud574\uc11c\ub294 \uc870\uae30 \uc9c4\ub2e8\uacfc \uc801\uc808\ud55c \uad00\ub9ac\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uac10\uc5fc\uc5d0 \ub300\ud55c \uc0dd\ub9ac\uc801 \ubc18\uc751\uc758 \uac1c\uc778\ucc28\uac00 \ud06c\uace0, \ud328\ud608\uc99d\uc758 \uc9d5\ud6c4\uc640 \uc99d\uc0c1\uc774 \ube44\ud2b9\uc774\uc801\uc774\uc5b4\uc11c \uc870\uae30 \uc9c4\ub2e8\uc774 \uc5b4\ub835\uc2b5\ub2c8\ub2e4. \uc774\ub7f0 \uc774\uc720\ub85c, \ud328\ud608\uc99d\uc758 \uc9c4\ub2e8\uc744 \uc704\ud55c \ub2e4\uc218\uc758 \uc7a0\uc7ac\uc801\uc778 \uc0dd\uccb4\ud45c\uc9c0\uc790\uac00 \uc870\uc0ac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub4e4 \ubd84\uc790\ub294 \uc8fc\ub85c \uac10\uc5fc\uc5d0 \ub300\ud55c \uc120\ucc9c\uc131 \uba74\uc5ed \ubc18\uc751\uc758 \ucd08\uae30 \ubcd1\uc778\uc5d0 \uad00\uc5ec\ud558\uba70, \ub9ce\uc740 \uacbd\uc6b0 \uc9c4\ub2e8\uc801 \uac00\uce58\ubfd0\ub9cc \uc544\ub2c8\ub77c \uc608\ud6c4\uc801 \uac00\uce58\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \ud328\ud608\uc99d\uc758 \uc608\ud6c4 \ud45c\uc9c0\uc790\ub294 \uc885\uc885, \ud328\ud608\uc99d\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c \uc7a5\uae30 \uae30\ub2a5\uc7a5\uc560\uc5d0 \uad00\ub828\ub418\uace0, \uadf8\ub9ac\uace0 \uc774\ub4e4 \uc608\ud6c4 \uc0dd\uccb4\ud45c\uc9c0\uc790\ub97c \ud45c\uc801\uc73c\ub85c \ud558\ub294 \ud328\ud608\uc99d\uc5d0 \ub300\ud55c \uce58\ub8cc\uc81c\uc758 \uac1c\ubc1c\uc774 \uc2dc\ub3c4\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \ucd5c\uadfc \uae30\uc220\uc758 \ubc1c\uc804\uc73c\ub85c \ub9c8\uc774\ud06c\ub85c\ubc14\uc774\uc634 \ubc0f \ube44-\ucf54\ub529 RNA\uc640 \uac19\uc740 \uc0c8\ub85c\uc6b4 \uc720\ud615\uc758 \uc0dd\uccb4\ud45c\uc9c0\uc790\uac00 \uac1c\ubc1c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc9d1\uc740 \uba74\uc5ed\uacc4\uc758 \ubc1c\ub2ec\uacfc \uc131\uc219, \ubcd1\uc6d0\uade0\uc5d0 \ub300\ud55c \ubcf4\ud638\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc7a5 \uc138\uade0\ubd88\uade0\ud615\uc740 \ud328\ud608\uc99d\uc758 \ubc1c\ubcd1\uacfc \uc9c4\ud589\uc744 \uc704\ud55c \uac15\ub825\ud55c \uc0dd\uccb4\ud45c\uc9c0\uc790\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4. miRNA \ubc0f \uae34 \ube44\ucf54\ub529 RNA\ub97c \ube44\ub86f\ud55c \ube44\ucf54\ub529 RNA\ub294 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \ub2e4\uc591\ud55c \ubc29\uc2dd\uc73c\ub85c \uc870\uc808\ud558\uc9c0\ub9cc, \ud328\ud608\uc99d\uc758 \ubc1c\ubcd1\uae30\uc804\uc5d0\uc11c \uc774\ub4e4\uc758 \uae30\ub2a5 \ubc0f \uae30\uc804\uc740 \uc644\uc804\ud788 \uc774\ud574\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud328\ud608\uc99d\uc758 \ubc1c\ubcd1\uae30\uc804\uc5d0\uc11c \uc774\ub4e4 \uc0c8\ub85c\uc6b4 \uc0dd\uccb4\ud45c\uc9c0\uc790\uc758 \uc5ed\ud560 \ubc0f \uc774\ub4e4 \uc0c8\ub85c\uc6b4 \uc0dd\uccb4\ud45c\uc9c0\uc790\uc758 \ubd84\uc11d\uc744 \uc704\ud55c \ucd5c\uc801 \uc815\uaddc\ud654 \uc804\ub7b5\uc758 \uac1c\ubc1c\uc744 \ube44\ub86f\ud55c \ucd94\uac00 \ud3c9\uac00\uac00 \uc774\ub4e4\uc758 \uc7a5\ub798 \uc784\uc0c1\uc801 \uc774\uc6a9\uc744 \uc704\ud574 \ud544\uc694\ud560 \uac83\uc785\ub2c8\ub2e4 [5].<\/p>\n

\ucc38\uace0 \ubb38\ud5cc:<\/em><\/p>\n

[1] <\/a>Sepsis Clinical Care Standard 2022<\/p>\n

[2]<\/a> Global Burden of Disease study<\/p>\n

[3]<\/a>\u00a0Gregoriano, C.et al. (2020) \u2018Role of procalcitonin use in the management of sepsis\u2019, Journal of Thoracic Disease, 12(S1). doi:10.21037\/jtd.2019.11.63.<\/p>\n

[4]<\/a>\u00a0K\u00fcng, E.et al. (2022) \u2018Cut-off values of serum interleukin-6 for culture-confirmed sepsis in neonates\u2019, Pediatric Research, 93(7), pp. 1969\u20131974. doi:10.1038\/s41390-022-02329-9.<\/p>\n

[5]\u00a0Kim, M.-H. and Choi, J.-H. (2020) \u2018An update on sepsis biomarkers\u2019, Infection & Chemotherapy, 52(1), p. 1.doi:10.3947\/ic.2020.52.1.1.<\/p>\n

\n

\uc774 \uae30\uc0ac\ub294 \uc6d0\ub798 Roche Diagnostics Australia<\/a>\uc5d0 \uac8c\uc7ac\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

\ud328\ud608\uc99d\uacfc \ud328\ud608\uc131 \uc1fc\ud06c\uc5d0 \ub300\ud55c \uc138 \ubc88\uc9f8 \uad6d\uc81c \ud569\uc758 \uc815\uc758 (Sepsis-3)\ub294 \ud328\ud608\uc99d\uc744 ‘\uac10\uc5fc\uc5d0 \ub300\ud55c \uc870\uc808\uc7a5\uc560\uac00 \ubc1c\uc0dd\ub41c \uc219\uc8fc \ubc18\uc751\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c \uce58\uba85\uc801\uc778 \uc7a5\uae30 \uae30\ub2a5 \uc7a5\uc560’\ub85c \uc815\uc758\ud569\ub2c8\ub2e4. \ud328\ud608\uc131 \uc1fc\ud06c\ub294 ‘\uadfc\ubcf8\uc801\uc778 \uc21c\ud658, \uc138\ud3ec \ubc0f \ub300\uc0ac \uc774\uc0c1\uc774 \ud328\ud608\uc99d \ub2e8\ub3c5\ubcf4\ub2e4 \uc0ac\ub9dd \uc704\ud5d8\uc774 \ub354 \ud070 \ud328\ud608\uc99d\uc758 \ud558\uc704 \uc9d1\ud569’\ub85c \uc815\uc758\ub429\ub2c8\ub2e4. \ud328\ud608\uc99d\uc740 \ub2e8\uc77c \uc9c4\ub2e8 \uac80\uc0ac\uac00 \uc5c6\uae30 \ub54c\ubb38\uc5d0 \uc784\uc0c1 \uc9c4\ub2e8\uc785\ub2c8\ub2e4. \uc0dd\ub9ac\ud559\uc801 \uc774\uc0c1\uacfc \uac80\uc0ac\uc2e4 \uc774\uc0c1\uc774 \ubaa8\ub450 […]<\/p>\n","protected":false},"author":1,"featured_media":85902,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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