{"id":146524,"date":"2023-05-26T03:04:59","date_gmt":"2023-05-26T03:04:59","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%ed%98%b8%eb%a5%b4%eb%aa%ac-%ec%9a%94%eb%b2%95-%eb%b0%8f-%ec%9e%84%ec%8b%a0%ea%b3%bc-%ea%b4%80%eb%a0%a8%eb%90%9c-vte-%ec%9c%84%ed%97%98-%eb%b0%8f-%ea%b4%80%eb%a6%aclai-heng-lee-%eb%b6%80%ea%b5%90\/"},"modified":"2026-01-23T09:37:52","modified_gmt":"2026-01-23T09:37:52","slug":"vte-associated-with-hormone-therapy-and-pregnancy-assoc-prof-lai-heng-lee-on-risk-and-management","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/ko\/disease-area\/womens-health\/vte-associated-with-hormone-therapy-and-pregnancy-assoc-prof-lai-heng-lee-on-risk-and-management\/","title":{"rendered":"\ud638\ub974\ubaac \uc694\ubc95 \ubc0f \uc784\uc2e0\uacfc \uad00\ub828\ub41c VTE: \uc704\ud5d8 \ubc0f \uad00\ub9ac(Lai Heng Lee \ubd80\uad50\uc218)"},"content":{"rendered":"

Roche Diagnostics\uc774 \ud6c4\uc6d0\ud558\ub294 \uc5f0\ub840 \ud589\uc0ac\uc778 pro-COAG \ud589\uc0ac<\/a>(2022)\uc5d0\uc11c Lai Heng Lee \uad50\uc218\ub294 \ud638\ub974\ubaac \uce58\ub8cc \ubc0f \uc784\uc2e0\uacfc \uad00\ub828\ub41c \uc784\uc2e0 \uc911 VTE(\uc815\ub9e5 \ud608\uc804 \uc0c9\uc804\uc99d)\uc758 \uc704\ud5d8\uc5d0 \ub300\ud574 \ud1b5\ucc30\ub825 \uc788\ub294 \ubc1c\ud45c\ub97c \uc9c4\ud589\ud588\uc2b5\ub2c8\ub2e4. \ub2e4\uc74c\uc740 \uba87 \uac00\uc9c0 \uc8fc\uc694 \ub0b4\uc6a9\uc785\ub2c8\ub2e4.<\/p>\n

\ud638\ub974\ubaac \uad00\ub828 \uc815\ub9e5 \ud608\uc804 \uc0c9\uc804\uc99d(VTE)<\/h2>\n

\uc80a\uc740 \uc5ec\uc131\uc758 VTE \ubc1c\uc0dd\ub960\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \uc5f0\uac04 1\/10,000\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ubcf5\ud569 \uacbd\uad6c \ud53c\uc784\uc81c(COC) \ubc0f \ud638\ub974\ubaac \ub300\uccb4 \uc694\ubc95(HRT)\uc758 \uc0ac\uc6a9\uacfc \uac19\uc740 \ud638\ub974\ubaac \uc694\ubc95\uc740 VTE\uc758 \uc704\ud5d8 \uc99d\uac00\uc640 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. COC\ub294 \ube44\uc0ac\uc6a9\uc790\uc5d0 \ube44\ud574 VTE \uc704\ud5d8\uc744 \uc57d 2~4\ubc30 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \uadf8\ub7fc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \uc808\ub300\uc801\uc778 \uc704\ud5d8\uc740 0.1% \ubbf8\ub9cc\uc73c\ub85c \uc5ec\uc804\ud788 \ub0ae\uc740 \uac83\uc73c\ub85c \ucd94\uc815\ub429\ub2c8\ub2e4. HRT\uc758 \uacbd\uc6b0 VTE \uc704\ud5d8\uc758 \uc99d\uac00\uac00 \uc57d 1.5~2\ubc30\ub85c \ub354 \uc644\ub9cc\ud569\ub2c8\ub2e4.<\/p>\n

COC\ub294 \uc8fc\ub85c \uc12c\uc720\uc18c\uc6d0, \ud504\ub85c\ud2b8\ub86c\ube48, \uc778\uc790 VII, VIII \ubc0f X\uc758 \uc218\uce58\ub97c \uc99d\uac00\uc2dc\ucf1c \uc751\uace0 \ub2e8\ubc31\uc9c8\uc758 \uc99d\uac00\ub97c \uc720\ub3c4\ud568\uc73c\ub85c\uc368 \uc9c0\ud608 \uc2dc\uc2a4\ud15c\uc5d0 \ubcc0\ud654\ub97c \uc77c\uc73c\ud0a4\uace0 \uacfc\uc751\uace0 \uc0c1\ud0dc\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4.\u00a0\ub610\ud55c \ud56d\ud2b8\ub86c\ube48 \ubc0f S\ub2e8\ubc31(PS)\uacfc \uac19\uc740 \ucc9c\uc5f0 \ud56d\uc751\uace0\uc81c \uc218\uce58\ub97c \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. PS\ub294 C\ub2e8\ubc31(PC)\uc758 \ubcf4\uc870 \uc778\uc790\uc774\ubbc0\ub85c PS \ud65c\uc131\uc758 \uac10\uc18c\ub294 \ud6c4\ucc9c\uc801\uc73c\ub85c \ud65c\uc131\ud654\ub41c PC \uc800\ud56d\uc131(APC) \uc0c1\ud0dc\ub85c \uc774\uc5b4\uc9d1\ub2c8\ub2e4.<\/p>\n

\ub9ce\uc740 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 COC\uc758 VTE \uc704\ud5d8\uc740 \ud53c\uc784\uc81c\uc758 \uc131\ubd84\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9c0\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ub354 \ub192\uc740 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc6a9\ub7c9(>30\u03bcg\uc758 \uc5d0\ud2f0\ub2d0 \uc5d0\uc2a4\ud2b8\ub77c\ub514\uc62c)\uacfc \ub4dc\ub85c\uc2a4\ud53c\ub808\ub17c, \ub370\uc18c\uac8c\uc2a4\ud2b8\ub810, \uac8c\uc2a4\ud1a0\ub374 \ubc0f \uc2dc\ud504\ub85c\ud14c\ub860 \uc544\uc138\ud14c\uc774\ud2b8\uc640 \uac19\uc740 COC\ub97c \ud3ec\ud568\ud558\ub294 \ube44\ub808\ubcf4\ub178\ub974\uac8c\uc2a4\ud2b8\ub810 \ud504\ub85c\uac8c\uc2a4\ud2f4\uc774 VTE \uc704\ud5d8\uc758 \uc99d\uac00\uc640 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ub9c8\ucc2c\uac00\uc9c0\ub85c VTE\uc758 \uc704\ud5d8\ub3c4 HRT \uc81c\ud488\uc758 \uc870\uc131\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4. \uc5d0\uc2a4\ud14c\ub974\ud654 \uc5d0\uc2a4\ud2b8\ub85c\uac90(EE)\uacfc \uacf5\uc561 \ub9d0 \uc5d0\uc2a4\ud2b8\ub85c\uac90(CEE)\uc774 \ubaa8\ub450 VTE\uc758 \uc720\uc758\ubbf8\ud55c \uc704\ud5d8\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ub2e4\ub9cc EE\uc758 \uc704\ud5d8\uc740 CEE\uc5d0 \ube44\ud574 \ub35c\ud55c \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4. \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc5d0 \ud504\ub85c\uac8c\uc2a4\ud14c\ub860\uc744 \ucd94\uac00\ud558\uba74 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ub2e8\ub3c5 \uc0ac\uc6a9 \uc2dc\ubcf4\ub2e4 VTE \uc704\ud5d8\uc774 \uc99d\uac00\ud558\ub294 \uac83\uc73c\ub85c \uc0dd\uac01\ub418\uc5c8\uc9c0\ub9cc \ucd5c\uadfc \uac80\ud1a0 \ubc0f \uba54\ud0c0 \ubd84\uc11d\uc5d0\uc11c\ub294 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc5d0 \ud504\ub85c\uac8c\uc2a4\ud14c\ub860\uc744 \ucd94\uac00\ud560 \uacbd\uc6b0\uc758 \uc720\uc758\ubbf8\ud55c \ucd94\uac00 \uc704\ud5d8\uc740 \ubcf4\uace0\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc8fc\uc0ac\uc81c \ud504\ub85c\uac8c\uc2a4\ud2f4, \ud328\uce58, \uc9c8 \ub9c1\uacfc \uac19\uc740 \ube44\uacbd\uad6c\uc6a9 \ub300\uc548\ub3c4 VTE \uc704\ud5d8 \uc99d\uac00\uc640 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc5d0\ud1a0\ub178\uac8c\uc2a4\ud2b8\ub810\uc774 \ud568\uc720\ub41c \ud504\ub85c\uac8c\uc2a4\ud2f4 \uc804\uc6a9 \ud53c\ud558 \uc784\ud50c\ub780\ud2b8\ub294 \ube44\uc0ac\uc6a9\uc790\uc5d0 \ube44\ud574 \uc704\ud5d8\uc774 1.4\ubc30 \ub192\uc9c0\ub9cc \uc808\ub300\uc801\uc778 \uc704\ud5d8\uc740 10,000\ub144 \ub178\ucd9c \ub2f9 1.7\uac74\uc73c\ub85c \ub0ae\uc2b5\ub2c8\ub2e4. \ud504\ub85c\uac8c\uc2a4\ud14c\ub860 \uc804\uc6a9 \uc790\uad81 \ub0b4 \uc7a5\uce58, \ud504\ub85c\uac8c\uc2a4\ud14c\ub860 \uc804\uc6a9 \uc54c\uc57d \ub610\ub294 \uacbd\ud53c \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc804\uc6a9 HRT \uc81c\uc81c\ub294 VTE \uc704\ud5d8 \uc99d\uac00\uc640 \uad00\ub828\uc774 \uc5c6\ub294 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4.<\/p>\n

HRT\ub294 \ud3d0\uacbd \ud6c4 \uc5ec\uc131\uc758 \uc2ec\ud608\uad00 \uc0ac\uac74\uacfc \uace8\ub2e4\uacf5\uc99d\uc744 \uc608\ubc29\ud558\uace0 \ud3d0\uacbd\uacfc \uad00\ub828\ub41c \uc99d\uc0c1\uc744 \uc644\ud654\ud558\uae30 \uc704\ud574 1960\ub144\ub300\uc5d0 \ucc98\uc74c \ub3c4\uc785\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud604\uc7ac \ub370\uc774\ud130\uc5d0 \ub530\ub974\uba74 HRT\uc640 \uad00\ub828\ub41c VTE, \uc720\ubc29\uc554, \uc2ec\ud608\uad00 \uc9c8\ud658\uc5d0 \ub300\ud55c \ubcf4\ud638 \ubd80\uc871\uc758 \uc704\ud5d8\uc740 \uace8\ub2e4\uacf5\uc99d \uac10\uc18c\ub85c \uc778\ud55c \uc774\uc810\uc744 \uc0c1\uc1c4\ud569\ub2c8\ub2e4. \ub610\ud55c \uc784\uc0c1 \uc99d\uc0c1\uc774 \uc5c6\ub294 \ud3d0\uacbd \ud6c4 \uc5ec\uc131\uc758 \uc0b6\uc758 \uc9c8\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uc9c0 \ubabb\ud558\ub294 \uac83\uc73c\ub85c \ubcf4\uc774\ubbc0\ub85c HRT\ub294 \uc784\uc0c1 \uc99d\uc0c1\uc744 \uc870\uc808\ud574\uc57c \ud558\ub294 \ud3d0\uacbd \ud6c4 \uc5ec\uc131\uc5d0\uac8c\ub9cc \uce58\ub8cc\uc801 \uc120\ud0dd\uc774 \ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\ud638\ub974\ubaac \uce58\ub8cc\ub97c \ubc1b\ub294 \uc5ec\uc131\uc740 VTE \uc704\ud5d8\uc744 \ub354\uc6b1 \uc99d\uac00\uc2dc\ud0a4\uac70\ub098 \uc0c1\uc2b9 \uc791\uc6a9\uc744 \uc77c\uc73c\ud0ac \uc218 \uc788\ub294 \ub2e4\ub978 VTE \uc704\ud5d8 \uc694\uc778\uc744 \uc778\uc9c0\ud558\ub294 \uac83\uc774 \uc911\uc694\ud569\ub2c8\ub2e4. 50\uc138 \uc774\uc0c1\uc758 \uc5ec\uc131\uc740 VTE \uc704\ud5d8\uc774 COC\ub97c \ubcf5\uc6a9\ud558\ub294 \uacbd\uc6b0 6.3\ubc30, HRT\ub97c \ubcf5\uc6a9\ud558\ub294 \uacbd\uc6b0 4\ubc30 \uc99d\uac00\ud569\ub2c8\ub2e4. \ube44\ub9cc\uacfc \ud761\uc5f0\ub3c4 VTE \uc704\ud5d8\uc744 \ub192\uc785\ub2c8\ub2e4. COC \ub610\ub294 HRT\ub97c \ubcf5\uc6a9\ud558\ub294 \ub3d9\uc548 VTE \uc704\ud5d8\uc744 \uc904\uc774\uae30 \uc704\ud574 \ube44\ub9cc\uacfc \ud761\uc5f0\uc744 \ud53c\ud558\ub294 \uac74\uac15\ud55c \uc0dd\ud65c \uc2b5\uad00\uc5d0 \ub300\ud574 \ud658\uc790\uc640 \uc0c1\ub2f4\ud558\ub294 \uac83\uc774 \uc911\uc694\ud569\ub2c8\ub2e4. \uc218\uc220 \uc608\uc815\uc778 \ud658\uc790\ub294 \ud638\ub974\ubaac \uce58\ub8cc \uc911\uc774\uac70\ub098 VTE \uac00\uc871\ub825\uc774 \uc788\ub294 \uacbd\uc6b0 \uc758\uc0ac\uc5d0\uac8c \uc54c\ub824 \uc801\uc808\ud55c VTE \uc608\ubc29 \uc870\uce58\ub97c \ucde8\ud560 \uc218 \uc788\ub3c4\ub85d \ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\ud638\ub974\ubaac \uce58\ub8cc\ub97c \ubc1b\ub294 \uc5ec\uc131\uc758 \ucd5c\ucd08 VTE \ubc1c\uc0dd \ud6c4, \uc7ac\ubc1c\uc131 VTE\uc758 \ub204\uc801 \uc704\ud5d8\uc5d0 \ub300\ud55c \ucd94\uc815\uce58\ub294 \uc5f0\uac04 0.4%\uc5d0\uc11c 5%, 5\ub144 \ub3d9\uc548 2.3%\uc5d0\uc11c 9%\uc5d0 \uc774\ub974\ub294 \ub113\uc740 \ubc94\uc704\uc5d0 \uac78\uccd0 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c \uac04 \uc704\ud5d8\uc758 \ucc28\uc774\ub294 \uc5f0\uad6c \uc5f0\ub3c4\uc5d0 \ub530\ub77c \uc2dc\uac04\uc774 \uc9c0\ub0a8\uc5d0 \ub530\ub77c \ub2e4\ub978 \uc138\ub300\uc758 COC\uac00 \uc0ac\uc6a9\ub418\uc5c8\uae30 \ub54c\ubb38\uc77c \uc218\ub3c4 \uc788\uace0, \uc5f0\uad6c\ub9c8\ub2e4 \ub2e4\ub978 \ud3ec\ud568 \uae30\uc900\uc774 \uc801\uc6a9\ub418\uc5b4 \uc5f0\uad6c \uac04\uc5d0 \uc774\uc9c8\uc801\uc778 \uc704\ud5d8\uc774 \ubc1c\uc0dd\ud588\uae30 \ub54c\ubb38\uc77c \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ucd5c\uadfc \uc5c5\ub370\uc774\ud2b8\ub41c \uc624\ub9ac\uc9c0\ub110 REVERSE \ucf54\ud638\ud2b8\uc758 \ud558\uc704 \uadf8\ub8f9 \ubd84\uc11d\uc5d0\uc11c HERDOO2 \uc810\uc218 \uae30\uc900 \uc800\uc704\ud5d8\uad70 \uc5ec\uc131\uc758 \uacbd\uc6b0, COC \uc0ac\uc6a9\uc790\ub294 \uc5f0\uac04 0.4%\uc758 \uc7ac\ubc1c\ub960\uc744 \ubcf4\uc778 \ubc18\uba74 \ube44\uc0ac\uc6a9\uc790\ub294 \uc5f0\uac04 1.4%\uc758 \uc7ac\ubc1c\ub960\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uace0\uc704\ud5d8\uad70 \uc5ec\uc131\uc758 \uacbd\uc6b0, COC \uc0ac\uc6a9\uc790\uc758 \uc7ac\ubc1c\ub960\uc740 \uc5f0\uac04 3.5%, \ube44\uc0ac\uc6a9\uc790\uc758 \uc7ac\ubc1c\ub960\uc740 6.1%\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc774\ub7ec\ud55c \uc5ec\uc131\uc758 \uacbd\uc6b0 \ud56d\uc751\uace0 \uce58\ub8cc \uae30\uac04\uc744 \uacb0\uc815\ud560 \ub54c VTE\uc758 \ub2e4\ub978 \uc704\ud5d8 \uc694\uc778\uc744 \uace0\ub824\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uce58\ub8cc\uc801 \ud56d\uc751\uace0\uc81c\ub97c \ud22c\uc5ec\ud558\ub294 \ub3d9\uc548 COC\ub97c \uc0ac\uc6a9\ud55c \uc9c0\uc18d\uc801\uc778 \ud638\ub974\ubaac \uce58\ub8cc\uac00 \uc7ac\ubc1c \uc99d\uac00\uc640 \uad00\ub828\uc774 \uc5c6\ub2e4\ub294 \uac83\uc740 \uc548\uc2ec\ud560 \uc218 \uc788\ub294 \uc0ac\uc2e4\uc785\ub2c8\ub2e4. \ud56d\uc751\uace0 \uce58\ub8cc\ub97c \uc911\ub2e8\ud560 \uacbd\uc6b0, VTE \uc7ac\ubc1c \uc704\ud5d8\uc744 \ucd5c\uc18c\ud654\ud558\uae30 \uc704\ud574 COC \ub610\ub294 HRT\ub97c \uc911\ub2e8\ud574\uc57c \ud569\ub2c8\ub2e4. \uc784\uc2e0 \uc608\ubc29\uc744 \uc704\ud574 \ud504\ub85c\uac8c\uc2a4\ud2f4 \uc804\uc6a9 IUD \ub610\ub294 \ud504\ub85c\uac8c\uc2a4\ud2f4 \uc804\uc6a9 \ud53c\ud558 \uc784\ud50c\ub780\ud2b8\uc640 \uac19\uc774 VTE \uc7ac\ubc1c \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0a4\uc9c0 \uc54a\ub294 \ub2e4\ub978 \ud615\ud0dc\uc758 \ud53c\uc784\ubc95\uc744 \uace0\ub824\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \u00a0\uc804\ubc18\uc801\uc73c\ub85c \ud638\ub974\ubaac \uc694\ubc95\uc744 \ubc1b\ub294 \uc5ec\uc131\uc5d0\uc11c \uc774\ub7ec\ud55c VTE \uc7ac\ubc1c \uc704\ud5d8 \ucd94\uc815\uce58\ub294 \ub9e4\uc6b0 \ub0ae\uc73c\uba70, \ub2e4\ub978 \uc704\ud5d8 \uc694\uc778\uc774 \uc5c6\ub294 \uacbd\uc6b0 \uc7a5\uae30 \ud56d\uc751\uace0 \uc694\ubc95\uc740 \uc815\ub2f9\ud654\ub420 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc720\uc804\uc131 \ud608\uc804 \uc131\ud5a5\uc99d\uc774 \uc788\ub294 \uc5ec\uc131\uc774 \ud638\ub974\ubaac \uc694\ubc95\uc744 \ubc1b\ub294 \ub3d9\uc548\uc758 \ud608\uc804 \uc704\ud5d8\uc5d0 \ub300\ud574\uc11c\ub3c4 \ub9ce\uc740 \uad00\uc2ec\uc774 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. V \uc778\uc790 \ub77c\uc774\ub374(FVL)\uacfc \ud504\ub85c\ud2b8\ub86c\ube48 \uc720\uc804\uc790 \ub3cc\uc5f0\ubcc0\uc774(PGM)\ub294 \ubc31\uc778 \uc778\uad6c\uc5d0\uc11c \ud754\ud788 \ubc1c\uc0dd\ud558\ub294 \ube44\uad50\uc801 \uac00\ubcbc\uc6b4 \ud615\ud0dc\uc758 \ub450 \uac00\uc9c0 \uc720\uc804\uc131 \ud608\uc804 \uc131\ud5a5\uc99d\uc73c\ub85c, VTE\uc758 \uc704\ud5d8\uc744 4~7\ubc30 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \ud56d\ud2b8\ub86c\ube48, PC \ubc0f PS \uacb0\ud54d\uc740 \ud754\ud558\uc9c0\ub294 \uc54a\uc9c0\ub9cc \ud608\uc804 \uc0dd\uc131 \uc704\ud5d8\uc774 \ud6e8\uc52c \ub354 \uac15\ub825\ud569\ub2c8\ub2e4. \ud56d\ud2b8\ub86c\ube48 \uacb0\ud54d\uc740 VTE \uc704\ud5d8\uc744 50\ubc30 \uc99d\uac00\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ubcf4\uace0\ub418\uc5c8\uc73c\uba70, PC \ubc0f PS \uacb0\ud54d\uc740 VTE \uc704\ud5d8\uc744 10~15\ubc30 \uc99d\uac00\uc2dc\ud0a4\ub294 \uac83\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc720\uc804\uc801 \ud608\uc804 \uc131\ud5a5\uc99d\uc774 \uc788\uc73c\uba74 OC\ub97c \ubcf5\uc6a9\ud558\ub294 \uc5ec\uc131\uc758 \ud608\uc804 \uc704\ud5d8\uc774 \ud06c\uac8c \uc99d\uac00\ud569\ub2c8\ub2e4.<\/p>\n

\ub2e4\uc2dc \ud55c \ubc88 \uac15\uc870\ud558\uc9c0\ub9cc, \uc808\ub300\uc801\uc778 \uc704\ud5d8\uc744 \uc544\ub294 \uac83\uc740 \ud608\uc804 \uc131\ud5a5\uc99d\uc758 \uac1c\uc778 \ubcd1\ub825 \ub610\ub294 \uac00\uc871\ub825\uc774 \uc788\ub294 \ud658\uc790\uc640 \uc0c1\ub2f4\ud560 \ub54c \uc0c1\ud669\uc744 \uac1d\uad00\uc801\uc73c\ub85c \ud30c\uc545\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4. FVL \ub610\ub294 PGM\uc774 \uc788\ub294 COC\ub97c \ubcf5\uc6a9\ud558\ub294 \uc5ec\uc131\uc5d0\uc11c VTE\uc758 \uc808\ub300\uc801\uc778 \uc704\ud5d8\uc740 100\ub144 \ubcf5\uc6a9\ub2f9 0.45~2\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c VTE \uc704\ud5d8\uc740 \uc784\uc2e0 \uc704\ud5d8\uacfc \ube44\uad50\ud588\uc744 \ub54c \uc77c\ubd80 \uc5ec\uc131\uc5d0\uac8c\ub294 \ub354 \uac10\uc218\ud560 \uc218 \uc788\ub294 \uc218\uc900\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uac15\ub825\ud55c \ub370\uc774\ud130\uac00 \ubd80\uc871\ud55c \ub354 \uac15\ub825\ud55c \ud608\uc804 \uc131\ud5a5\uc99d\uc758 \uacbd\uc6b0 \uc808\ub300\uc801\uc778 \uc704\ud5d8\uc740 100\ub144 \ubcf5\uc6a9\ub2f9 4.3~4.5\ub85c \ubcf4\uace0\ub418\uc5b4 \ub354 \ub9ce\uc740 \uc8fc\uc758\uc640 \ub300\uccb4 \ud53c\uc784 \ubc29\ubc95\uc774 \uad8c\uc7a5\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7fc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 COC \uc0ac\uc6a9 \uc804\uc5d0 \ud608\uc804 \uc131\ud5a5\uc99d\uc5d0 \ub300\ud55c \uc815\ub2f9\ud654\ub418\uc9c0 \uc54a\uc740 \ub300\uaddc\ubaa8 \uc815\uae30 \uc120\ubcc4\uac80\uc0ac\ub294 \uad8c\uc7a5\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc120\ubcc4\uac80\uc0ac\ub294 \ub2e8 \ud55c \uac74\uc758 \ud608\uc804\uc131 \uc0ac\uac74\uc744 \uc608\ubc29\ud558\uae30 \uc704\ud574 \uc218\ub9ce\uc740 \uc5ec\uc131\uc744 \uc2dc\ud5d8\ud558\uace0 COC \uc0ac\uc6a9\uc744 \uc790\uc81c\ud558\ub3c4\ub85d \uad8c\uace0\ud574\uc57c \ud558\ubbc0\ub85c \ube44\uc6a9 \ud6a8\uc728\uc801\uc774\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \ube44\uad50\uc801 \uacbd\ubbf8\ud55c \ud608\uc804 \uc131\ud5a5\uc99d\uc758 \uacbd\uc6b0 VTE\uc758 \uc808\ub300\uc801\uc778 \uc704\ud5d8\uc774 \uc801\uc73c\uba70 \ub300\ubd80\ubd84\uc758 VTE \uc0ac\uac74\uc740 \uc720\uc804\uc801 \ud608\uc804 \uc131\ud5a5\uc99d\uc774 \ud655\uc778\ub418\uc9c0 \uc54a\uc740 \uc5ec\uc131\uc5d0\uac8c\uc11c \ubc1c\uc0dd\ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud56d\ud2b8\ub86c\ube48, PC \ubc0f PS \uacb0\ud54d, FV \ub77c\uc774\ub374 \ubc0f FII G20210A\uc5d0 \ub300\ud55c \ub3d9\ud615\uc811\ud569\uc131 \ub4f1 \ud6e8\uc52c \ub192\uc740 \ud608\uc804 \uc704\ud5d8\uacfc \uad00\ub828\ub41c \uc911\uc99d \ud608\uc804 \uc131\ud5a5\uc99d \ubcf4\uc778\uc790\uc758 \ubb34\uc99d\uc0c1 \uce5c\ucc99\uc758 \uacbd\uc6b0 COC \ud22c\uc5ec \uc804 \uc120\ud0dd\uc801 \uc2dc\ud5d8\uc774 \uc720\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc784\uc2e0 \uad00\ub828 \uc815\ub9e5 \ud608\uc804 \uc0c9\uc804\uc99d<\/h2>\n

\uc784\uc2e0\uc740 \uc0dd\ub9ac\uc801 \ubcc0\ud654\uc640 \ud568\uaed8 \uc751\uace0 \uc778\uc790(VII, VIII, X \ubc0f \ud3f0 \ube4c\ub808\ube0c\ub780\ud2b8 \uc778\uc790)\uc758 \uc218\uce58\ub97c \uc99d\uac00\uc2dc\ud0a4\ub294 \ub3d9\uc2dc\uc5d0 \uc790\uc5f0 \ud56d\uc751\uace0\uc81c(PS)\uc758 \uc218\uce58\ub97c \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uacfc\uc751\uace0 \uc0c1\ud0dc\ub294 \ud558\uc9c0\uc758 \uc815\ub9e5 \uc6b8\ud608\uc5d0 \ub300\ud55c \uac10\uc218\uc131 \uc99d\uac00 \ubc0f \uace8\ubc18 \ud608\uad00\uc758 \ub0b4\ud53c \uc190\uc0c1\uacfc \ud568\uaed8 \ube44\uc815\uc0c1 \uc815\ub9e5 \ud608\uc804 \ubc1c\ubcd1\uc758 \uadfc\uac04\uc774 \ub418\ub294 Virchow\uc758 \uace0\uc804\uc801\uc778 \uc138 \uac00\uc9c0 \ubd80\ud608\uc804 \uc778\uc790\ub97c \ubaa8\ub450 \ucda9\uc871\ud558\uc5ec VTE\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4.<\/p>\n

\uc784\uc2e0 \uc911 VTE\uc758 \uc704\ud5d8\uc740 \uc784\uc2e0 1,000\uac74 \uc911 1\uac74\uaf34\ub85c \ubc1c\uc0dd\ud558\uba70, \uc0b0\uc804 \ubc0f \uc0b0\ud6c4 \uae30\uac04\uc5d0 \ube44\uc2b7\ud55c \ube44\uc728\ub85c VTE\uac00 \ubc1c\uc0dd\ud569\ub2c8\ub2e4. \uc0b0\ud6c4 \uae30\uac04\uc774 \uc0b0\uc804 \uae30\uac04\ubcf4\ub2e4 \uc9e7\uae30 \ub54c\ubb38\uc5d0 \uc77c\uc77c VTE \uc704\ud5d8\uc774 \ub354 \ub192\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc704\ud5d8 \uc99d\uac00\ub294 \uc0b0\ud6c4 12\uc8fc\uae4c\uc9c0 \uc9c0\uc18d\ub418\uba70, \ucd9c\uc0b0 \ud6c4 \uccab 6\uc8fc \ub3d9\uc548 \uc704\ud5d8\uc774 \uac00\uc7a5 \ud07d\ub2c8\ub2e4.<\/p>\n

\ud3d0 \uc0c9\uc804\uc99d(PE)\uc740 \uce58\ub8cc\ud558\uc9c0 \uc54a\uace0 \ubc29\uce58\ud560 \uacbd\uc6b0 \ud658\uc790\uc758 25%\uc5d0\uc11c \uce58\uba85\uc801\uc785\ub2c8\ub2e4. \ub530\ub77c\uc11c VTE\ub294 \uc11c\uc591 \uc778\uad6c\uc5d0\uc11c \uc0b0\ubaa8 \uc0ac\ub9dd\uc758 17%\ub97c \ucc28\uc9c0\ud558\ub294 \uc0b0\ubaa8 \uc774\ud658\uc728\uacfc \uc0ac\ub9dd\ub960\uc758 \uc8fc\uc694 \uc6d0\uc778\uc785\ub2c8\ub2e4. \uc801\uc808\ud55c \ud608\uc804 \uc608\ubc29 \uc870\uce58\ub97c \uc801\uc6a9\ud560 \uc218 \uc788\ub3c4\ub85d \uc784\uc2e0 \uc911 VTE \ubc1c\ubcd1 \uc704\ud5d8 \uc694\uc778\uc744 \ud30c\uc545\ud558\uace0 \uacc4\uce35\ud654\ud558\ub294 \uac83\uc774 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\uc784\uc2e0\uacfc \uad00\ub828\ub41c VTE\uc758 \uc704\ud5d8 \uacc4\uce35\ud654 \ubc0f \uad00\ub9ac\uc5d0 \ub300\ud55c \ub9ce\uc740 \uac00\uc774\ub4dc\ub77c\uc778\uc774 \uc788\uc9c0\ub9cc, \uc774\ub294 \uc8fc\ub85c \ube44\uc784\uc2e0 \ud658\uc790\uc640 \uc11c\uc591 \uc778\uad6c\uc758 \uc784\uc2e0 \ud658\uc790 \uc0ac\ub840 \uc2dc\ub9ac\uc988\uc5d0\uc11c \ucd94\uc815\ub41c \ub370\uc774\ud130\ub97c \uae30\ubc18\uc73c\ub85c \ud569\ub2c8\ub2e4. \u00a0\ud604\uc9c0 \ub370\uc774\ud130\ub97c \uae30\ubc18\uc73c\ub85c \ud604\uc9c0 \uac00\uc774\ub4dc\ub77c\uc778\uc744 \uac1c\ubc1c\ud558\ub294 \uac83\uc774 \uc911\uc694\ud569\ub2c8\ub2e4. \uc2f1\uac00\ud3ec\ub974\uc5d0\uc11c\ub294 Chapter of Physicians\uc640 College of Obstetrics and Gynaecologist\uac00 \ud611\ub825\ud558\uc5ec \uc774\ub7ec\ud55c \uac00\uc774\ub4dc\ub77c\uc778\uacfc \uc774\uc6a9 \uac00\ub2a5\ud55c \ud604\uc9c0 \ub370\uc774\ud130\ub97c \uac80\ud1a0\ud558\uc5ec \uc784\uc2e0 \uad00\ub828 VTE \uad00\ub9ac\ub97c \uc704\ud55c \ud569\uc758\ub41c \uad8c\uace0\uc548\uc744 \uac1c\ubc1c\ud588\uc2b5\ub2c8\ub2e4. VTE \uc704\ud5d8\uc758 \uacc4\uce35\ud654\ub294 Royal College of Obstetricians and Gynecologists(\uc601\uad6d)\uc758 \uadf8\ub9b0\ud0d1 \uac00\uc774\ub4dc\ub77c\uc778(Greentop Guideline) 37a\uc5d0\uc11c \ucc44\ud0dd\ud55c \uac83\uc744 \ud604\uc9c0 \ub370\uc774\ud130\uc640 \uc784\uc0c1\uc758\uc758 \uc758\uacac\uc744 \ubc14\ud0d5\uc73c\ub85c \uc218\uc815\ud558\uc5ec \uc801\uc6a9\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uac00\uc774\ub4dc\ub77c\uc778\uc5d0 \ud3ec\ud568\ub41c VTE \ubc1c\ubcd1 \uc704\ud5d8 \uc694\uc778\uc740 \uc774\uc804 VTE \ubcd1\ub825, \uc720\uc804\uc131 \ud608\uc804 \uc131\ud5a5\uc99d, \ud658\uc790\uc758 \uae30\uc874 \uc704\ud5d8 \uc694\uc778, \uc0b0\uacfc\uc801 \uc704\ud5d8 \uc694\uc778 \ubc0f \uae30\ud0c0 \uc77c\uc2dc\uc801 \uc704\ud5d8 \uc694\uc778\uc5d0 \uadfc\uac70\ud558\uc5ec \uacb0\uc815\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uac01 \uc704\ud5d8 \uc694\uc778\uc5d0 \ubd80\uc5ec\ub418\ub294 \uc810\uc218\ub294 \uac01 \uc704\ud5d8 \uc694\uc778\uc5d0 \ub300\ud55c \ud608\uc804 \uc704\ud5d8\uc758 \uac00\uc911\uce58\uc5d0 \ub530\ub77c \uacb0\uc815\ub429\ub2c8\ub2e4. \ud608\uc804 \uc608\ubc29\uc744 \uc704\ud55c \uad8c\uace0\uc548\uc740 \uc810\uc218 \ub610\ub294 \uc704\ud5d8 \uc810\uc218\uc5d0 \ub530\ub77c \uacb0\uc815\ub429\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc784\uc2e0 \uc9c4\ub2e8\uc744 \ubc1b\uc740 \ud6c4 \uc0b0\uc804 \ucd1d\uc810\uc774 4\uc810 \uc774\uc0c1\uc774\uba74 \ud608\uc804 \uc608\ubc29\uc744 \uace0\ub824\ud558\uace0 3\uc810\uc778 \uacbd\uc6b0 \uc784\uc2e0 28\uc8fc\ubd80\ud130 \ud608\uc804 \uc608\ubc29\uc744 \uace0\ub824\ud569\ub2c8\ub2e4. \ucd9c\uc0b0 \ud6c4 \ud608\uc804 \uc608\ubc29 \uc804\ub7b5\ub3c4 \uc810\uc218 \ub9e4\ud2b8\ub9ad\uc2a4\uc5d0 \ub530\ub77c \uacb0\uc815\ub429\ub2c8\ub2e4.<\/p>\n

VTE\uc758 \uc704\ud5d8\uc740 \uc5ed\ub3d9\uc801\uc774\uba70 \uc784\uc2e0\uc774 \uc9c4\ud589\ub428\uc5d0 \ub530\ub77c \uc0c8\ub85c\uc6b4 \uc704\ud5d8 \uc694\uc778\uc774 \ub098\ud0c0\ub098\uac70\ub098 \uc774\uc804 \uc704\ud5d8 \uc694\uc778\uc774 \ud574\uacb0\ub428\uc5d0 \ub530\ub77c \ubcc0\ud654\ud558\ubbc0\ub85c \uc784\uc2e0\uacfc \uc0b0\uc695\uae30 \ub0b4\ub0b4 \ub2e4\uc591\ud55c \uc2dc\uc810\uc5d0 VTE \uc704\ud5d8\uc5d0 \ub300\ud55c \ud3c9\uac00\ub97c \ubc18\ubcf5\ud558\ub294 \uac83\uc774 \uc911\uc694\ud569\ub2c8\ub2e4. \ucd9c\ud608 \uc704\ud5d8\uc744 \ud3c9\uac00\ud558\ub294 \uac83\ub3c4 \uc911\uc694\ud569\ub2c8\ub2e4. \ud658\uc790\uac00 \ud56d\uc751\uace0\uc81c \uc608\ubc29\uc5d0 \uc801\ud569\ud558\uc9c0 \uc54a\uc740 \uacbd\uc6b0, \uc555\ubc15 \uc7a5\uce58\ub098 \uc2a4\ud0c0\ud0b9\uc744 \uc774\uc6a9\ud55c \uae30\uacc4\uc801 \uc608\ubc29\uc744 \uace0\ub824\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc2f1\uac00\ud3ec\ub974 \ud569\uc758 \uad8c\uace0\uc548\uc5d0\uc11c \ubcc0\uacbd\ub41c \uc0ac\ud56d\uc740 \uc720\uc804\uc131 \ud608\uc804 \uc131\ud5a5\uc99d\uacfc \uc0b0\ubaa8\uc758 \uc5f0\ub839 \uc99d\uac00\uc5d0 \uac00\uc911\uce58\ub97c \ubd80\uc5ec\ud558\ub294 \uac83\uc785\ub2c8\ub2e4. \ud56d\ud2b8\ub86c\ube48(AT) \uacb0\ud54d, PC \ubc0f PS \uacb0\ud54d\uacfc \uac19\uc740 \ub354 \uc2ec\uac01\ud55c \ud615\ud0dc\uc758 \uc720\uc804\uc131 \ud608\uc804 \uc131\ud5a5\uc99d\uc740 \uc11c\uc591 \uc778\uad6c\uc5d0 \ube44\ud574 \uc544\uc2dc\uc544\uc5d0\uc11c \ub354 \ud754\ud569\ub2c8\ub2e4(\uac00\uc7a5 \uc2ec\uac01\ud55c AT \uacb0\ud54d\uc740 VTE \uc704\ud5d8\uc744 50\ubc30 \uc99d\uac00\uc2dc\ud0a4\uace0 PC \ubc0f PS \uacb0\ud54d\uc740 \uc704\ud5d8\uc744 10~15\ubc30 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4). \ub2f9\uc0ac \uc5f0\uad6c \uadf8\ub8f9\uc740 \ud56d\ud2b8\ub86c\ube48 \uacb0\ud54d\uc758 \uc704\ud5d8 \uc810\uc218\ub97c 4\uc810\uc73c\ub85c \ubd80\uc5ec\ud574\uc57c \ud558\uba70, \uc774 \uc704\ud5d8 \uc694\uc778\ub9cc\uc73c\ub85c\ub3c4 \uc784\uc2e0\uc774 \uc9c4\ub2e8\ub418\uba74 \ud608\uc804 \uc608\ubc29 \uc694\ubc95\uc744 \uc2dc\uc791\ud574\uc57c \ud55c\ub2e4\ub294 \ub370 \uc758\uacac\uc744 \ubaa8\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n

S\ub2e8\ubc31 \ub610\ub294 C\ub2e8\ubc31 \uacb0\ud54d\uc774 \uc788\uace0 VTE \uac00\uc871\ub825\uacfc \uac19\uc740 \ucd94\uac00\uc801\uc778 VTE \uc704\ud5d8 \uc694\uc778\uc774 \uc788\ub294 \ud658\uc790\ub294 \uc0b0\uc804 \ubc0f \uc0b0\ud6c4 \uc608\ubc29(\uc0b0\ud6c4 6\uc8fc\uae4c\uc9c0)\uc744 \uace0\ub824\ud574\uc57c \ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud608\uc804 \uc131\ud5a5\uc99d\uc758 \uc784\uc0c1\uc801 \uc911\uc694\uc131\uacfc \uc704\ud5d8 \uacc4\uce35\ud654\ub97c \uacb0\uc815\ud558\uae30 \uc704\ud574\uc11c\ub294 \ub354 \ub9ce\uc740 \uc544\uc2dc\uc544 \ub370\uc774\ud130\uac00 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\ud604\uc7ac \ubb38\ud5cc\uc5d0\uc11c \ud608\uc804\uc99d\uc758 \uc704\ud5d8 \uc694\uc778\uc778 \ub098\uc774\uc640 \uad00\ub828\ub41c \ub370\uc774\ud130\ub294 \uc0c1\ucda9\ub418\ub294 \ubd80\ubd84\uc774 \uc788\uc73c\ubbc0\ub85c, 2004\ub144\ubd80\ud130 2016\ub144\uae4c\uc9c0 12\ub144 \ub3d9\uc548 2\uac1c\uc758 3\ucc28 \uc0b0\ubd80\uc778\uacfc \ubcd1\uc6d0(KKH \ubc0f SGH)\uc5d0\uc11c \uc784\uc2e0\uacfc \uad00\ub828\ub41c VTE\uac00 \uc788\ub294 \uc5ec\uc131 89\uba85\uacfc \ub300\uc870\uad70 926\uba85\uc744 \ub300\uc0c1\uc73c\ub85c \uc2e4\uc2dc\ud55c \ucd5c\uadfc \ud604\uc9c0 \uc5f0\uad6c\ub97c \uc0b4\ud3b4\ubd24\uc2b5\ub2c8\ub2e4. \uadf8 \uacb0\uacfc 35\uc138 \uc774\uc0c1\uc758 \ub098\uc774\ub294 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ubbf8\ud55c VTE \uc704\ud5d8 \uc694\uc778\uc774 \uc544\ub2cc \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ud55c\uad6d \uc5f0\uad6c\uc5d0\uc11c\ub3c4 \ub9c8\ucc2c\uac00\uc9c0\ub85c \uc5f0\ub839 \uc99d\uac00\uac00 \uc784\uc2e0 \uc911 VTE\uc640 \uad00\ub828\uc774 \uc5c6\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc601\uad6d\uc758 \ub300\uaddc\ubaa8 \uc778\uad6c \uae30\ubc18 \ucf54\ud638\ud2b8 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc784\uc2e0\uc744 \uc81c\uc678\ud558\uace0 \uac00\uc7a5 \ub192\uc740 \uc5f0\ub839\ub300(35~44\uc138)\uc758 \uc5ec\uc131\uc740 25~34\uc138 \uc5ec\uc131\ubcf4\ub2e4 VTE \ubc1c\uc0dd\ub960\uc774 50% \ub354 \ub192\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc774 \uc5f0\uad6c\ub294 \ub610\ud55c \uc0b0\uc804\uc5d0\ub294 \uc5f0\ub839\uc5d0 \ub530\ub77c VTE \ubc1c\uc0dd\ub960\uc774 \uc99d\uac00\ud558\uc9c0 \uc54a\uc558\uc9c0\ub9cc, \uc0b0\ud6c4\uc5d0\ub294 35\uc138 \uc774\uc0c1\uc758 \uc5ec\uc131\uc774 25~34\uc138\uc758 \uc5ec\uc131\uc5d0 \ube44\ud574 \uc704\ud5d8\uc774 70% \ub192\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc704\uc6d0\ud68c\ub294 \uc774\uc6a9 \uac00\ub2a5\ud55c \uc99d\uac70\ub97c \ubc14\ud0d5\uc73c\ub85c \ud608\uc804\uc99d \uc704\ud5d8\uc5d0 \ub300\ud55c \uc0b0\ud6c4 \uc704\ud5d8 \ud3c9\uac00\uc5d0\uc11c\ub9cc \ub098\uc774\ub97c \ud608\uc804\uc99d \uc704\ud5d8 \uc694\uc778\uc73c\ub85c \uc0ac\uc6a9\ud558\uae30\ub85c \uacb0\uc815\ud588\uc2b5\ub2c8\ub2e4. 35\uc138\uac00 \ub118\ub294 \uace0\ub839 \uc0b0\ubaa8\ub294 \ud608\uc804 \uc608\ubc29\uc744 \uc704\ud55c \uc0b0\ud6c4 \ud3c9\uac00\uc758 \uc77c\ubd80\uc5d0\ub9cc \ud608\uc804\uc99d \uc704\ud5d8 \uc694\uc778\uc73c\ub85c\uc11c \ud3ec\ud568\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud655\uc9c4\ub41c \uc0c8 VTE\uc758 \uad00\ub9ac\uc5d0\uc11c \ud56d\uc751\uace0\ub294 \uce58\ub8cc\uc758 \ucd08\uc11d\uc785\ub2c8\ub2e4. \uce58\ub8cc\ud558\uc9c0 \uc54a\uace0 \ubc29\uce58\ud558\uba74 \uc2ec\ubd80 \uc815\ub9e5 \ud608\uc804\uc99d(DVT)\uc758 25%\uac00 \uc784\uc0c1\uc801\uc73c\ub85c \uad00\ub828\ub41c PE\ub85c \ubc1c\uc804\ud558\uba70, \ubd80\uc801\uc808\ud558\uac8c \uce58\ub8cc\ub41c VTE\uc758 \uacbd\uc6b0 \uc7ac\ubc1c\uc131 VTE\uac00 10~15\ubc30 \uc99d\uac00\ud569\ub2c8\ub2e4. \uc801\uc808\ud55c \uce58\ub8cc\uc801 \uc6a9\ub7c9\uacfc \uc801\uc808\ud55c \ud56d\uc751\uace0 \uce58\ub8cc \uae30\uac04\uc758 \uc911\uc694\uc131\uc740 \uc544\ubb34\ub9ac \uac15\uc870\ud574\ub3c4 \uc9c0\ub098\uce58\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ud56d\uc751\uace0\uc81c\ub97c \uc120\ud0dd\ud560 \ub54c\ub294 \uc0b0\ubaa8\uc758 \uc120\ud638\ub3c4\ubfd0\ub9cc \uc544\ub2c8\ub77c \uc0b0\ubaa8\uc640 \ud0dc\uc544\uc758 \ud569\ubcd1\uc99d\uc744 \uace0\ub824\ud558\ub294 \uac83\uc774 \uc911\uc694\ud569\ub2c8\ub2e4. \uc0b0\ubaa8\uc5d0\uac8c\ub294 \uce58\ub8cc \ubd80\uc871\uc73c\ub85c \uc778\ud55c \ud608\uc804 \ud569\ubcd1\uc99d\uacfc \uacfc\ub2e4 \ud56d\uc751\uace0\ub85c \uc778\ud55c \ucd9c\ud608 \ud569\ubcd1\uc99d\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ud56d\uc751\uace0\uc81c\uac00 \ud0dc\ubc18\uc744 \ud1b5\uacfc\ud558\uba74 \ud0dc\uc544\uc5d0\uac8c \uae30\ud615 \uc720\ubc1c\uc131 \ubc0f \ucd9c\ud608 \ud569\ubcd1\uc99d\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc800\ubd84\uc790\ub7c9 \ud5e4\ud30c\ub9b0(LMWH)\uc740 \uc784\uc2e0 \uc911 VTE \uce58\ub8cc \uc2dc \uac00\uc7a5 \ub9ce\uc774 \uc0ac\uc6a9\ub418\ub294 \ud56d\uc751\uace0\uc81c\uc785\ub2c8\ub2e4. \uc774\ub294 \ud22c\uc5ec\uac00 \uac04\ud3b8\ud558\uace0, \ubbf8\ubd84\ud68d \ud5e4\ud30c\ub9b0(UFH)\uc5d0 \ube44\ud574 \uace8\ub2e4\uacf5\uc99d \uc704\ud5d8\uc774 \ub0ae\uc73c\uba70, \ucd9c\ud608\ub960\uc774 \uac10\uc18c\ud558\uace0 \ud5e4\ud30c\ub9b0\uc73c\ub85c \uc778\ud55c \ud608\uc18c\ud310 \uac10\uc18c\uc99d\uc758 \uc704\ud5d8\uc774 \ube44\uad50\uc801 \ub0ae\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. UFH\uc640 LMWH\ub294 \ubaa8\ub450 \ud0dc\ubc18\uc744 \ud1b5\uacfc\ud558\uc9c0 \uc54a\uc73c\ubbc0\ub85c \uae30\ud615 \uc720\ubc1c\uc131 \ub610\ub294 \ud0dc\uc544 \ucd9c\ud608\uc758 \uc704\ud5d8\uacfc \uad00\ub828\uc774 \uc5c6\uc2b5\ub2c8\ub2e4. \ube44\ud0c0\ubbfc K \uae38\ud56d\uc81c\ub294 \ud0dc\ubc18\uc744 \ud1b5\uacfc\ud558\uc5ec \uc640\ud30c\ub9b0 \ubc30\uc544 \ubcd1\uc99d(\uc548\uba74 \ubc0f \uc0ac\uc9c0 \uc800\ud615\uc131\uc99d, \uc810\uc0c1 \uace8\ub2e8 \uc774\ud615\uc131\uc99d)\uc744 \uc720\ubc1c\ud558\ubbc0\ub85c \ud53c\ud574\uc57c \ud569\ub2c8\ub2e4. \u00a0\ub610\ud55c \uc640\ud30c\ub9b0\uc740 \uc784\uc2e0 \uc190\uc2e4, \ud0dc\uc544 \ud56d\uc751\uace0 \ubc0f \ucd9c\ud608\uacfc\ub3c4 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc608\uc678\uc801\uc778 \uc0c1\ud669\uc774 \uc544\ub2c8\ub77c\uba74 \uc640\ud30c\ub9b0\uc740 \ud53c\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4. \ub2e4\ube44\uac00\ud2b8\ub780, \uc544\ud53d\uc0ac\ubc18, \uc5d0\ub3c5\uc0ac\ubc18, \ub9ac\ubc14\ub85d\uc0ac\ubc18\uacfc \uac19\uc740 \uc9c1\uc811 \uacbd\uad6c\uc6a9 \ud56d\uc751\uace0\uc81c(DOAC)\ub294 \ud0dc\ubc18\uc744 \ud1b5\uacfc\ud558\uae30 \ub54c\ubb38\uc5d0 \uad8c\uc7a5\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc720\uc0b0 \ubc0f \ud0dc\uc544 \uae30\ud615 \uc99d\uac00\uac00 \ubcf4\uace0\ub418\uc5c8\uc73c\uba70 \uc784\uc2e0 \uc911 \uc548\uc804\uc131 \ub370\uc774\ud130\uac00 \ubd80\uc871\ud569\ub2c8\ub2e4.<\/p>\n

\ud56d\uc751\uace0\uc758 \uacbd\uc6b0, \uc784\uc2e0 \uae30\uac04 \ub3d9\uc548 \uc0b0\ud6c4 \ucd5c\uc18c 6\uc8fc\uae4c\uc9c0, \ucd5c\uc18c \ucd1d 3\uac1c\uc6d4 \ub3d9\uc548 \uce58\ub8cc\uc801 \uc6a9\ub7c9\uc758 \ud56d\uc751\uace0\uc81c\ub97c \uc720\uc9c0\ud574\uc57c \ud569\ub2c8\ub2e4. \ucda9\ubd84\ud55c \uae30\uac04\uc758 \uce58\ub8cc\uc801 \ud56d\uc751\uace0\uc81c \ud22c\uc5ec \ud6c4\uc5d0\ub3c4 \ud658\uc790\uac00 \uc5ec\uc804\ud788 \uc784\uc2e0 \uc911\uc778 \uacbd\uc6b0, \ud22c\uc5ec \uc6a9\ub7c9\uc744 \uc608\ubc29\uc801 \uc6a9\ub7c9\uc73c\ub85c \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud658\uc790\ub294 \ud56d\uc751\uace0\uc81c\ub97c \uc911\ub2e8\ud558\uae30 \uc804\uc5d0 \ub2e4\uc2dc \ud55c \ubc88 VTE \uc704\ud5d8 \uc810\uc218\ub97c \ubc1b\uc544\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\ubd84\ub9cc\uc744 \uc704\ud55c \uacbd\ub9c9 \uc678 \ub9c8\ucde8\ub294 \ud22c\uc5ec \uc2dc\uae30\uc5d0 \ud2b9\ud788 \uc8fc\uc758\ub97c \uae30\uc6b8\uc5ec\uc11c \ud574\uc57c \ud569\ub2c8\ub2e4. \ud658\uc790\uc640 \ub17c\uc758 \ud6c4 \uac1c\ubcc4\uc801\uc73c\ub85c \uacb0\uc815\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uacbd\ub9c9 \uc678 \uce74\ud14c\ud130 \uc0bd\uc785 \uc804\uc5d0 PTT\uac00 \uc815\uc0c1\uc774\uace0 4~6\uc2dc\uac04 \ub3d9\uc548 \ud45c\uc900 \ud5e4\ud30c\ub9b0\uc744 \ud22c\uc5ec\ud558\uc9c0 \uc54a\uc740 \uacbd\uc6b0 \uc548\uc804\ud569\ub2c8\ub2e4. LMWH\ub97c \ud22c\uc5ec\ubc1b\ub294 \ud658\uc790\uc758 \uacbd\uc6b0, \uacbd\ub9c9 \uc678 \ub9c8\ucde8\ub294 \ub9c8\uc9c0\ub9c9 \uc608\ubc29\uc801 \ud22c\uc5ec \ucd5c\uc18c 12\uc2dc\uac04 \ud6c4, \ub9c8\uc9c0\ub9c9 \uce58\ub8cc\uc801 LMWH \ud22c\uc5ec 24\uc2dc\uac04 \ud6c4\uc5d0 \ud22c\uc5ec\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud56d\uc751\uace0 \ubc0f \ubd84\ub9cc \uacc4\ud68d\uc740 \uc0b0\ubd80\uc778\uacfc \ubc0f \ud608\uc561 \uc804\ubb38\uc758 \ub610\ub294 \ub0b4\uacfc \uc758\uc0ac \uc678\uc5d0\ub3c4 \ub9c8\ucde8\uacfc \uc758\uc0ac\uc640 \ud568\uaed8 \uc218\ub9bd\ud574\uc57c \ud569\ub2c8\ub2e4. \uc81c\uc655 \uc808\uac1c \uc218\uc220\uc740 \uc0b0\uacfc\uc801 \uc774\uc720\ub85c\ub9cc \ud45c\uc2dc\ub418\uba70 \ubd84\ub9cc \ubc29\uc2dd\uc744 \uc9c0\uc6d0\ud558\uae30 \uc704\ud55c \ud56d\uc751\uace0 \uacc4\ud68d\uc774 \uc218\ub9bd\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uce58\ub8cc\uc801 \uc6a9\ub7c9\uc758 \ud56d\uc751\uace0\uc81c\ub97c \ud22c\uc5ec \uc911\uc778 \ud658\uc790\uc758 \uacbd\uc6b0, \uce58\ub8cc\uc801 \ud56d\uc751\uace0\uc81c \ud22c\uc5ec\ub97c \uc911\ub2e8\ud55c \uc0c1\ud0dc\uc5d0\uc11c \ubd84\ub9cc\uc744 \uc608\uc815\ud558\uba74 \uacbd\ub9c9 \uc678 \ub9c8\ucde8\uac00 \uc6a9\uc774\ud574\uc9c0\uace0 \uc0b0\ubaa8\uc758 \ucd9c\ud608 \uc704\ud5d8\uc774 \ub4e4\uc5b4\ub4e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ubc29\uc801 \uc6a9\ub7c9\uc758 LMWH\ub97c \ud22c\uc5ec \uc911\uc778 \ud658\uc790\uc758 \uacbd\uc6b0 \uc790\uc5f0 \ubd84\ub9cc\uc774 \uac00\ub2a5\ud560 \uc218 \uc788\uc73c\uba70, \uc9c4\ud1b5 \uc2dc\uc791 \uc2dc \ud56d\uc751\uace0\uc81c \ud22c\uc5ec\ub97c \uc911\ub2e8\ud558\uace0 \ud45c\uc900 \uc608\ubc29\uc801 LMWH\uc758 \ub9c8\uc9c0\ub9c9 \ud22c\uc5ec\uc640 \uacbd\ub9c9\uc678 \uce74\ud14c\ud130 \uc0ac\uc774\uc5d0 12\uc2dc\uac04 \uac04\uaca9\uc744 \ub450\uba74 \uc608\uc815\ub41c \ubd84\ub9cc\uc778\uc9c0 \uc790\uc5f0 \ubd84\ub9cc\uc778\uc9c0\uc5d0 \uad00\uacc4\uc5c6\uc774 \ub300\ubd80\ubd84\uc758 \uc0b0\ubaa8\uac00 \uacbd\ub9c9 \uc678 \ub9c8\ucde8\ub97c \ubc1b\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubd84\ub9cc \ud6c4\uc5d0\ub294 \uac00\uc7a5 \ucd5c\uadfc\uc758 \uce58\ub8cc\uc801 LMWH \uc8fc\uc0ac \ud6c4 24\uc2dc\uac04 \uc774\ub0b4\uc5d0 \uacbd\ub9c9 \uc678 \uce74\ud14c\ud130\ub97c \uc81c\uac70\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. \ucc99\ucd94 \ub9c8\ucde8 \uc0ac\uc6a9 \ud6c4 \ub610\ub294 \uacbd\ub9c9 \uc678 \uce74\ud14c\ud130 \uc81c\uac70 \ud6c4 \ucd5c\uc18c 4\uc2dc\uac04\uc774 \uc9c0\ub0a0 \ub54c\uae4c\uc9c0\ub294 LMWH\ub97c \ud22c\uc5ec\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. \ud658\uc790\uac00 \ucd9c\ud608 \uc704\ud5d8\uc774 \ub192\uc9c0 \uc54a\uace0, \uc9c0\ud608\uc774 \ud655\ubcf4\ub418\uc5b4 \uc788\uace0, \uc2e0\uc7a5 \uae30\ub2a5\uc774 \uc815\uc0c1\uc774\uace0, \uc751\uace0 \ubcd1\uc99d\uc774 \uc5c6\uc73c\uba70, \uacbd\ub9c9 \uc678 \ub9c8\ucde8 \ud6c4 \uc2e0\uacbd\ud559\uc801 \ud68c\ubcf5\uc774 \uc644\ub8cc\ub41c \uacbd\uc6b0, \ubd84\ub9cc 4~6\uc2dc\uac04 \ud6c4\uc5d0 \uc608\ubc29\uc801 LMWH \ud22c\uc5ec\ub97c \uc7ac\uac1c\ud558\uace0 \ubd84\ub9cc 24\uc2dc\uac04 \ud6c4\uc5d0 \uce58\ub8cc\uc801 LMWH \ud22c\uc5ec\ub97c \uc7ac\uac1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc0b0\ubaa8\uac00 LMWH \ub610\ub294 \uc640\ud30c\ub9b0\uc744 \ubcf5\uc6a9 \uc911\uc77c \ub54c \ubaa8\uc720 \uc218\uc720\ub294 \uc544\uae30\uc5d0\uac8c \uc548\uc804\ud569\ub2c8\ub2e4. DOAC\ub294 \ubaa8\uc720\ub85c \ubd84\ube44\ub418\uace0 \uc548\uc804\uc131 \ub370\uc774\ud130\uac00 \ubd80\uc871\ud558\uae30 \ub54c\ubb38\uc5d0 \uc218\uc720\ubd80\uc5d0\uac8c\ub294 \uad8c\uc7a5\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n

\ucc38\uace0 \ubb38\ud5cc:<\/em><\/p>\n

[1]<\/a> Oral contraceptives and hormone replacement therapy: How strong a risk factor for venous thromboembolism? \u00a0Leslie Skeith a,, Gr\u00b4egoire Le Gal, Marc A.Rodger. Thrombosis Research 202 (2021) 134\u2013138<\/p>\n

[2]<\/a> Reducing the Risk of Venous Thromboembolism during Pregnancy and the Puerperium RCOG Green-top Guideline No. 37a, 2015<\/p>\n

[3]<\/a> CONSENSUS STATEMENT on VENOUS THROMBOEMBOLISM IN PREGNANCY \u2013 RECOMMENDATIONS FOR PREVENTION, TREATMENT AND INVESTIGATION. College of Obstetricians and Gynaecologists (COGS), Chapter of Haematologists, College of Physicians, \uc2f1\uac00\ud3ec\ub974.<\/p>\n","protected":false},"excerpt":{"rendered":"

Roche Diagnostics\uc774 \ud6c4\uc6d0\ud558\ub294 \uc5f0\ub840 \ud589\uc0ac\uc778 pro-COAG \ud589\uc0ac(2022)\uc5d0\uc11c Lai Heng Lee \uad50\uc218\ub294 \ud638\ub974\ubaac \uce58\ub8cc \ubc0f \uc784\uc2e0\uacfc \uad00\ub828\ub41c \uc784\uc2e0 \uc911 VTE(\uc815\ub9e5 \ud608\uc804 \uc0c9\uc804\uc99d)\uc758 \uc704\ud5d8\uc5d0 \ub300\ud574 \ud1b5\ucc30\ub825 \uc788\ub294 \ubc1c\ud45c\ub97c \uc9c4\ud589\ud588\uc2b5\ub2c8\ub2e4. \ub2e4\uc74c\uc740 \uba87 \uac00\uc9c0 \uc8fc\uc694 \ub0b4\uc6a9\uc785\ub2c8\ub2e4. \ud638\ub974\ubaac \uad00\ub828 \uc815\ub9e5 \ud608\uc804 \uc0c9\uc804\uc99d(VTE) \uc80a\uc740 \uc5ec\uc131\uc758 VTE \ubc1c\uc0dd\ub960\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \uc5f0\uac04 1\/10,000\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ubcf5\ud569 \uacbd\uad6c \ud53c\uc784\uc81c(COC) \ubc0f \ud638\ub974\ubaac \ub300\uccb4 \uc694\ubc95(HRT)\uc758 \uc0ac\uc6a9\uacfc \uac19\uc740 \ud638\ub974\ubaac […]<\/p>\n","protected":false},"author":1,"featured_media":85734,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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