Infectious Diseases

HIV testing in the era of PrEP: Practical consideration and challenges in practice

HIV testing in the era of PrEP: Practical consideration and challenges in practice

Conventional HIV testing algorithms may be delayed or compromised in identifying HIV acquisition in the context of antiretroviral agent-based pre-exposure prophylaxis (PrEP). Data are available in delays of progression through the Feibig stages with the use of TDF/FTC PrEP, as well as lower viral load set points. Case reports of complete suppression of nucleic acid detection with PrEP use further

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Antimicrobial resistance and the role of procalcitonin (PCT)

Antimicrobial Resistance and the role of Procalcitonin (PCT)

Procalcitonin (PCT) plays a central role for successful antimicrobial stewardship programs. Originally considered a “sepsis biomarker”, PCT has evolved to aid in the de-escalation of antimicrobial therapy and help differentiate between bacterial versus non-bacterial infections. The University of California (UC), Davis Health system implemented PCT in late-2014. Procalcitonin was found in our studies to correlate with sepsis

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