The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defines sepsis as a ‘life-threatening organ dysfunction caused by a dysregulated host response to infection’. Septic shock is defined as ‘a subset of sepsis in which the underlying circulatory, cellular and metabolic abnormalities are associated with a greater risk of mortality than sepsis alone’. […]
September 13th marks World Sepsis Day, a global event designed to help raise awareness of a dangerous and often deadly condition. In the Asia Pacific region, the need for better sepsis care—including high-quality diagnostics to help identify and manage the condition—is particularly urgent. Globally, as many as 50 million people suffer from sepsis every year,
Sepsis care gaps in Asia demonstrate need for better diagnostics Read More »
Sepsis is a global killer. About 27 million people around the world develop sepsis every year, and some eight million people die from it, according to a November 2018 article in The Lancet [1]. This leaves 19 million people living with the long-term consequences of the infection. In Thailand alone, this translates to 175,000 infections with sepsis
Harnessing lactate POC values to deliver early sepsis diagnosis Read More »
Procalcitonin (PCT) plays a central role for successful antimicrobial stewardship programs. Originally considered a “sepsis biomarker”, PCT has evolved to aid in the de-escalation of antimicrobial therapy and help differentiate between bacterial versus non-bacterial infections. The University of California (UC), Davis Health system implemented PCT in late-2014. Procalcitonin was found in our studies to correlate with sepsis
Antimicrobial resistance and the role of procalcitonin (PCT) Read More »
Sepsis is one of the top reasons for admission to intensive care units (ICUs). This life–threatening, systemic reaction to infection is also a major cause of morbidity and mortality in hospitalised patients. Proper diagnosis of the cause of sepsis is crucial for making a decision on an appropriate treatment, and can increase the odds of
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