{"id":146972,"date":"2019-04-30T03:25:00","date_gmt":"2019-04-30T03:25:00","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/ctdna-mang-den-su-tu-tin-moi-trong-cuoc-chien-chong-lai-can-benh-ung-thu-nguy-hiem-nhat-o-trung-quoc\/"},"modified":"2026-02-20T07:23:14","modified_gmt":"2026-02-20T07:23:14","slug":"ctdna-provides-new-confidence-in-fight-against-chinas-deadliest-cancer","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/vi\/disease-area\/oncology\/ctdna-provides-new-confidence-in-fight-against-chinas-deadliest-cancer\/","title":{"rendered":"ctDNA mang \u0111\u1ebfn s\u1ef1 t\u1ef1 tin m\u1edbi trong cu\u1ed9c chi\u1ebfn ch\u1ed1ng l\u1ea1i c\u0103n b\u1ec7nh ung th\u01b0 nguy hi\u1ec3m nh\u1ea5t \u1edf Trung Qu\u1ed1c"},"content":{"rendered":"

Ung th\u01b0 ph\u1ed5i l\u00e0\u00a0lo\u1ea1i ung th\u01b0 ph\u1ed5 bi\u1ebfn nh\u1ea5t \u1edf Trung Qu\u1ed1c\u00a0[1] v\u00e0 g\u00e2y t\u1eed vong nhi\u1ec1u nh\u1ea5t. Kh\u00f4ng gi\u1ed1ng nh\u01b0 nhi\u1ec1u n\u01b0\u1edbc ph\u01b0\u01a1ng T\u00e2y, s\u1ed1 l\u01b0\u1ee3ng ch\u1ea9n \u0111o\u00e1n m\u1eafc ung th\u01b0 ph\u1ed5i c\u0169ng \u0111ang ti\u1ebfp t\u1ee5c t\u0103ng.\u00a0B\u1eb1ng c\u00e1ch khai th\u00e1c c\u00f4ng ngh\u1ec7 ctDNA, ch\u00fang t\u00f4i c\u00f3 c\u01a1 h\u1ed9i c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 vi\u1ec7c ch\u0103m s\u00f3c v\u00e0 k\u1ebft qu\u1ea3 l\u00e2m s\u00e0ng c\u1ee7a b\u1ec7nh nh\u00e2n. Theo truy\u1ec1n th\u1ed1ng, \u0111\u1ec3 x\u00e1c nh\u1eadn m\u1ed9t ch\u1ea9n \u0111o\u00e1n ung th\u01b0, m\u1ed9t kh\u1ed1i u nghi ng\u1edd l\u00e0 ung th\u01b0 s\u1ebd \u0111\u01b0\u1ee3c sinh thi\u1ebft v\u00e0 m\u00f4 \u0111\u01b0\u1ee3c g\u1eedi \u0111\u1ebfn \u0111\u1ec3 nh\u00f3m y t\u1ebf trong ph\u00f2ng x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n. Nh\u01b0ng vi\u1ec7c x\u00e1c \u0111\u1ecbnh ung th\u01b0 ch\u1ec9 v\u1edbi m\u1ed9t m\u1eabu nh\u1ecf c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn th\u00f4ng tin sai l\u1ec7ch, v\u00e0\u00a0sinh thi\u1ebft m\u00f4 l\u1eb7p l\u1ea1i kh\u00f4ng ph\u1ea3i l\u00fac n\u00e0o c\u0169ng kh\u1ea3 thi, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u0111\u1ed1i v\u1edbi ung th\u01b0 ph\u1ed5i. M\u1ed9t khi b\u1ec7nh nh\u00e2n \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb ung th\u01b0 ph\u1ed5i, vi\u1ec7c l\u1ea5y sinh thi\u1ebft m\u00f4 l\u1eb7p l\u1ea1i c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t th\u00e1ch th\u1ee9c v\u00e0 mang theo nh\u1eefng nguy c\u01a1 m\u00e0 b\u1ea5t k\u1ef3 th\u1ee7 thu\u1eadt x\u00e2m l\u1ea5n n\u00e0o c\u0169ng v\u1ed1n \u0111\u00e3 c\u00f3. C\u00e1c ph\u00f2ng x\u00e9t nghi\u1ec7m c\u00f3 chuy\u00ean m\u00f4n ph\u00f9 h\u1ee3p c\u00f3 th\u1ec3 \u0111\u01b0a ra cho b\u00e1c s\u0129 m\u1ed9t gi\u1ea3i ph\u00e1p thay th\u1ebf h\u1ea5p d\u1eabn trong nh\u1eefng t\u00ecnh hu\u1ed1ng nh\u01b0 v\u1eady. Sinh thi\u1ebft l\u1ecfng, t\u1ee9c \u0111o m\u1ee9c DNA kh\u1ed1i u t\u1ef1 do trong m\u00e1u (ctDNA), \u00edt x\u00e2m l\u1ea5n h\u01a1n v\u00e0 tr\u00e1nh \u0111\u01b0\u1ee3c c\u00e1c bi\u1ebfn ch\u1ee9ng li\u00ean quan \u0111\u1ebfn sinh thi\u1ebft. S\u1eed d\u1ee5ng d\u1eef li\u1ec7u di truy\u1ec1n v\u00e0 bi\u1ec3u sinh thu \u0111\u01b0\u1ee3c t\u1eeb ctDNA, nh\u00f3m x\u00e9t nghi\u1ec7m c\u00f3 th\u1ec3 cung c\u1ea5p cho b\u00e1c s\u0129 ung th\u01b0 d\u1eef li\u1ec7u v\u1edbi \u0111\u1ed9 ch\u00ednh x\u00e1c cao v\u1ec1 ki\u1ec3u gen v\u00e0 h\u00e0nh vi theo th\u1eddi gian th\u1ef1c \u0111\u1ec3 ki\u1ec3m so\u00e1t b\u1ec7nh t\u1ed1t h\u01a1n cho b\u1ec7nh nh\u00e2n.<\/p>\n

Khai m\u1edf th\u00f4ng tin phong ph\u00fa trong m\u1ed9t l\u1ecd m\u00e1u<\/h2>\n

V\u1edbi th\u1eddi gian b\u00e1n th\u1ea3i ng\u1eafn c\u1ee7a ctDNA, t\u1ee9c m\u1ed9t gi\u1edd ho\u1eb7c ng\u1eafn h\u01a1n, x\u00e9t nghi\u1ec7m n\u00e0y c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t ch\u1ec9 s\u1ed1 ch\u00ednh x\u00e1c v\u1ec1 g\u00e1nh n\u1eb7ng kh\u1ed1i u theo th\u1eddi gian th\u1ef1c khi ph\u1ea3n \u1ee9ng v\u1edbi li\u1ec7u ph\u00e1p [2]. Quy\u1ec1n truy c\u1eadp th\u00f4ng tin theo th\u1eddi gian th\u1ef1c n\u00e0y c\u00f3 th\u1ec3 gi\u00fap nh\u00f3m ch\u0103m s\u00f3c s\u1edbm ph\u00e1t hi\u1ec7n ra b\u1ea5t k\u1ef3 t\u1ed3n d\u01b0 kh\u1ed1i u n\u00e0o. Tr\u00ean th\u1ef1c t\u1ebf, ng\u01b0\u1eddi ta \u0111\u00e3 ch\u1ee9ng minh r\u1eb1ng\u00a0trong 72% b\u1ec7nh nh\u00e2n ung th\u01b0 ph\u1ed5i khu tr\u00fa, c\u00f3 th\u1ec3 x\u00e1c \u0111\u1ecbnh t\u1ed3n d\u01b0 kh\u1ed1i u b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng ctDNA s\u1edbm h\u01a1n 5,2 th\u00e1ng so v\u1edbi ch\u1ec9 s\u1eed d\u1ee5ng ch\u1ee5p chi\u1ebfu ch\u1ea9n \u0111o\u00e1n h\u00ecnh \u1ea3nh [3]. V\u00ed d\u1ee5: \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n ung th\u01b0 ph\u1ed5i kh\u00f4ng t\u1ebf b\u00e0o nh\u1ecf d\u01b0\u01a1ng t\u00ednh v\u1edbi \u0111\u1ed9t bi\u1ebfn th\u1ee5 th\u1ec3 y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng bi\u1ec3u b\u00ec (EGFR), t\u00ecnh tr\u1ea1ng kh\u00e1ng\u00a0thu\u1ed1c \u1ee9c ch\u1ebf tyrosine kinase \u0111ang d\u1ea7n xu\u1ea5t hi\u1ec7n l\u00e0 m\u1ed9t c\u01a1 h\u1ed9i kh\u00e1c \u0111\u1ec3 s\u1eed d\u1ee5ng ctDNA theo th\u1eddi gian th\u1ef1c nh\u1eb1m theo d\u00f5i qu\u00e1 tr\u00ecnh ti\u1ebfn h\u00f3a di truy\u1ec1n c\u1ee7a b\u1ec7nh. M\u1ed9t n\u1eeda s\u1ed1 b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng ch\u1ea5t \u1ee9c ch\u1ebf tyrosine kinase c\u00f3 \u0111\u1ed9t bi\u1ebfn EGFR T790M [4]. Wakelee et al \u0111\u00e3 minh ch\u1ee9ng trong b\u00e0i thuy\u1ebft tr\u00ecnh t\u1ea1i ASCO 2016 [5]\u00a0r\u1eb1ng ph\u00e2n t\u00edch EGFR trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 n\u01b0\u1edbc ti\u1ec3u c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n ch\u00ednh x\u00e1c v\u00e0 ch\u1ec9 ra nh\u1eefng \u0111\u1ed9t bi\u1ebfn n\u00e0y trong khi sinh thi\u1ebft kh\u00f4ng th\u1ec3 l\u00e0m v\u1eady do t\u00ednh kh\u00f4ng \u0111\u1ed3ng nh\u1ea5t c\u1ee7a kh\u1ed1i u. ctDNA c\u0169ng cho ph\u00e9p x\u00e1c \u0111\u1ecbnh nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y v\u1edbi th\u1eddi gian trung v\u1ecb l\u00e0 2,2 th\u00e1ng tr\u01b0\u1edbc khi b\u1ec7nh ti\u1ebfn tri\u1ec3n v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng [4],\u00a0theo nh\u01b0 Zheng et al ch\u1ee9ng minh.<\/p>\n

T\u1ea1o n\u00ean m\u1ed1i li\u00ean h\u1ec7 ch\u1eb7t ch\u1ebd h\u01a1n gi\u1eefa ph\u00f2ng kh\u00e1m v\u00e0 ph\u00f2ng x\u00e9t nghi\u1ec7m<\/h2>\n

C\u0169ng nh\u01b0 t\u1ea5t c\u1ea3 c\u00e1c c\u00f4ng ngh\u1ec7 m\u1edbi sinh, bi\u1ebft \u0111\u01b0\u1ee3c khi n\u00e0o n\u00ean \u00e1p d\u1ee5ng x\u00e9t nghi\u1ec7m ctDNA\u00a0v\u00e0 c\u00e1ch ph\u00e2n t\u00edch v\u00e0 di\u1ec5n gi\u1ea3i k\u1ebft qu\u1ea3 ch\u00ednh l\u00e0 ch\u00eca kh\u00f3a. Vi\u1ec7c c\u00f3 kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn m\u1ed9t nh\u00f3m x\u00e9t nghi\u1ec7m \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt nghi\u00ean c\u1ee9u m\u1edbi nh\u1ea5t v\u00e0 \u0111\u01b0\u1ee3c \u0111\u00e0o t\u1ea1o \u0111\u1ec3 cung c\u1ea5p ph\u00e2n t\u00edch ch\u00ednh x\u00e1c ch\u1ea5t l\u01b0\u1ee3ng cao c\u00f3 th\u1ec3 gi\u00fap c\u00e1c b\u00e1c s\u0129 ung th\u01b0 qu\u1ea3n l\u00fd b\u1ec7nh t\u1ed1t h\u01a1n cho b\u1ec7nh nh\u00e2n. Ph\u00e2n t\u00edch ctDNA x\u00e1c \u0111\u1ecbnh c\u00e1c \u0111\u1ed9t bi\u1ebfn ung th\u01b0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m d\u1ea5u \u1ea5n sinh h\u1ecdc cho m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c FDA ph\u00ea duy\u1ec7t trong 49% tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n [6]. C\u00e1c chuy\u00ean gia v\u1ec1 y h\u1ecdc x\u00e9t nghi\u1ec7m c\u1ea7n l\u00e0m vi\u1ec7c tay trong tay v\u1edbi c\u00e1c b\u00e1c s\u0129 ung th\u01b0 \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh khi n\u00e0o sinh thi\u1ebft l\u1ecfng c\u00f3 th\u1ec3 l\u00e0 c\u00f4ng c\u1ee5 ch\u1ea9n \u0111o\u00e1n th\u00edch h\u1ee3p nh\u1ea5t. Ch\u00fang t\u00f4i \u0111ang tr\u00ean \u0111\u1ec9nh c\u1ee7a vi\u1ec7c cung c\u1ea5p \u0111i\u1ec1u tr\u1ecb \u0111\u01b0\u1ee3c c\u00e1 nh\u00e2n h\u00f3a kh\u00f4ng ch\u1ec9 cho b\u1ec7nh nh\u00e2n t\u1ea1i th\u1eddi \u0111i\u1ec3m ch\u1ea9n \u0111o\u00e1n, m\u00e0 trong su\u1ed1t to\u00e0n b\u1ed9 th\u1eddi gian m\u1eafc b\u1ec7nh. ctDNA cung c\u1ea5p th\u00f4ng tin v\u1ec1 c\u1ea5u tr\u00fac di truy\u1ec1n c\u1ee7a ung th\u01b0 v\u00e0\u00a0t\u00ednh kh\u00f4ng \u0111\u1ed3ng nh\u1ea5t v\u1ed1n c\u00f3 c\u1ee7a n\u00f3. Lo\u1ea1i x\u00e9t nghi\u1ec7m n\u00e0y c\u0169ng c\u00f3 th\u1ec3 cung c\u1ea5p nh\u1eefng manh m\u1ed1i v\u1ec1 ti\u00ean l\u01b0\u1ee3ng, bao g\u1ed3m nguy c\u01a1 t\u00e1i ph\u00e1t v\u00e0 t\u1ef7 l\u1ec7 s\u1ed1ng th\u00eam to\u00e0n b\u1ed9. V\u1edbi th\u00f4ng tin m\u1ea1nh m\u1ebd v\u00e0 ch\u00ednh x\u00e1c t\u1eeb ph\u00f2ng x\u00e9t nghi\u1ec7m, c\u00e1c b\u00e1c s\u0129 ung th\u01b0 s\u1ebd s\u1edbm c\u00f3 th\u1ec3 tr\u1ea3 l\u1eddi m\u1ed9t s\u1ed1 c\u00e2u h\u1ecfi kh\u00f3 nh\u1ea5t m\u00e0 b\u1ec7nh nh\u00e2n c\u1ee7a h\u1ecd \u0111\u1eb7t ra v\u1edbi s\u1ef1 t\u1ef1 tin v\u00e0 ch\u1eafc ch\u1eafn h\u01a1n.<\/p>\n

T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/em><\/p>\n

[1]<\/a>\u00a0Zhou, C., 2014. Lung cancer molecular epidemiology in China: recent trends.\u00a0Translational Lung Cancer Research<\/i>, 3(5), pp.270-279.<\/p>\n

[2]<\/a> Corcoran, B.R., Chabner A.B., 2018. Application of Cell-free DNA Analysis to Cancer Treatment. New England Journal of Medicine<\/em>, 379, pp.1754-1765<\/p>\n

[3]<\/a> Chaudhuri, A.A, et al., 2018. Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling. American Association for Cancer Research<\/em>, 7(12), pp.1394-1403.<\/p>\n

[4]<\/a> Zheng, X.Y, et al., 2016. Plasma EGFR<\/em> T790M ctDNA status is associated with clinical outcome in advanced NSCLC patients with acquired EGFR-TKI resistance. Scientific Reports<\/em>, 6, 20913.<\/p>\n

[5]<\/a> Wakelee, A.H., et al., 2016.\u00a0Epidermal growth factor receptor (EGFR) genotyping of matched urine, plasma and tumor tissue from non-small cell lung cancer (NSCLC) patients (pts) treated with rociletinib. Journal of Clinical Oncology<\/em>, 34(15) supplementary<\/em>, pp.9001-9001.<\/p>\n

[6]<\/a> Zill, A.O., et al., 2016.\u00a0Somatic genomic landscape of over 15,000 patients with advanced-stage cancer from clinical next-generation sequencing analysis of circulating tumor DNA. Journal of Clinical Oncology<\/em>, 34(18), supplementary,<\/em>\u00a0LBA11501<\/p>\n

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B\u00e0i vi\u1ebft n\u00e0y d\u1ef1a tr\u00ean b\u00e0i thuy\u1ebft tr\u00ecnh \u201cChinh ph\u1ee5c ung th\u01b0: \u1ee8ng d\u1ee5ng ctDNA trong NSCLC\u201d\u00a0t\u1ea1i Belt and Road Diagnostic Summit Forum 2018 \u1edf T\u00f4 Ch\u00e2u, Trung Qu\u1ed1c.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Ung th\u01b0 ph\u1ed5i l\u00e0\u00a0lo\u1ea1i ung th\u01b0 ph\u1ed5 bi\u1ebfn nh\u1ea5t \u1edf Trung Qu\u1ed1c\u00a0[1] v\u00e0 g\u00e2y t\u1eed vong nhi\u1ec1u nh\u1ea5t. Kh\u00f4ng gi\u1ed1ng nh\u01b0 nhi\u1ec1u n\u01b0\u1edbc ph\u01b0\u01a1ng T\u00e2y, s\u1ed1 l\u01b0\u1ee3ng ch\u1ea9n \u0111o\u00e1n m\u1eafc ung th\u01b0 ph\u1ed5i c\u0169ng \u0111ang ti\u1ebfp t\u1ee5c t\u0103ng.\u00a0B\u1eb1ng c\u00e1ch khai th\u00e1c c\u00f4ng ngh\u1ec7 ctDNA, ch\u00fang t\u00f4i c\u00f3 c\u01a1 h\u1ed9i c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 vi\u1ec7c ch\u0103m […]<\/p>\n","protected":false},"author":1,"featured_media":83497,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"tags":[14754,14778,14777,14776],"pillarandcategory":[287,282,309,326],"reporter":[14779],"class_list":["post-146972","acf_article","type-acf_article","status-publish","has-post-thumbnail","hentry","tag-gia-tri-lam-sang","tag-giai-trinh-tu","tag-trung-quoc","tag-ung-thu-hoc","pillarandcategory-oncology","pillarandcategory-disease-area","pillarandcategory-operations","pillarandcategory-sequencing","reporter-xiuyu-cai"],"acf":[],"_links":{"self":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/146972","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article"}],"about":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/types\/acf_article"}],"author":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":3,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/146972\/revisions"}],"predecessor-version":[{"id":149037,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/146972\/revisions\/149037"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media\/83497"}],"wp:attachment":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media?parent=146972"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/tags?post=146972"},{"taxonomy":"pillarandcategory","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/pillarandcategory?post=146972"},{"taxonomy":"reporter","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/reporter?post=146972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}