{"id":147098,"date":"2022-05-05T00:59:50","date_gmt":"2022-05-05T00:59:50","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/early-check-dinh-hinh-chinh-sach-sang-loc-cho-tre-so-sinh-nhu-the-nao-voi-bang-chung-tot-hon\/"},"modified":"2026-02-23T07:13:43","modified_gmt":"2026-02-23T07:13:43","slug":"how-early-check-shapes-newborn-screening-policy-with-better-evidence","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/vi\/disease-area\/newborn-screening\/how-early-check-shapes-newborn-screening-policy-with-better-evidence\/","title":{"rendered":"Early Check \u0111\u1ecbnh h\u00ecnh ch\u00ednh s\u00e1ch s\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh nh\u01b0 th\u1ebf n\u00e0o v\u1edbi b\u1eb1ng ch\u1ee9ng t\u1ed1t h\u01a1n"},"content":{"rendered":"

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S\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh (NBS) l\u00e0 m\u1ed9t c\u00f4ng c\u1ee5 quan tr\u1ecdng \u0111\u1ec3 c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe con ng\u01b0\u1eddi, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u0111\u1ed1i v\u1edbi tr\u1ebb em m\u1eafc b\u1ec7nh hi\u1ebfm g\u1eb7p, nh\u1eefng tr\u1ebb c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i t\u1eeb vi\u1ec7c can thi\u1ec7p s\u1edbm. Tuy nhi\u00ean, \u1edf nhi\u1ec1u qu\u1ed1c gia, c\u00f3 th\u1ec3 m\u1ea5t nhi\u1ec1u n\u0103m \u0111\u1ec3 t\u1ea1o d\u1eef li\u1ec7u v\u00e0 x\u00e2y d\u1ef1ng c\u01a1 s\u1edf h\u1ea1 t\u1ea7ng c\u1ea7n thi\u1ebft \u0111\u1ec3 th\u00eam c\u00e1c t\u00ecnh tr\u1ea1ng m\u1edbi v\u00e0o panel NBS.<\/p>\n

T\u1ea1i Hoa K\u1ef3, c\u00e1c nh\u00e0 ho\u1ea1ch \u0111\u1ecbnh ch\u00ednh s\u00e1ch y t\u1ebf ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi m\u1ed9t th\u00e1ch th\u1ee9c b\u1ed5 sung trong vi\u1ec7c qu\u1ea3n l\u00fd c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh NBS: trong khi ch\u00ednh ph\u1ee7 li\u00ean bang c\u00f4ng b\u1ed1 c\u00e1c h\u01b0\u1edbng d\u1eabn chung v\u1ec1 s\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh th\u00ec t\u1eebng ti\u1ec3u bang \u0111\u01b0\u1ee3c t\u1ef1 do l\u1ef1a ch\u1ecdn x\u00e9t nghi\u1ec7m n\u00e0o mu\u1ed1n \u0111\u01b0a v\u00e0o c\u00e1c panel c\u00f3 ti\u1ec3u bang t\u00e0i tr\u1ee3. Do h\u1ec7 th\u1ed1ng ch\u1eafp v\u00e1 n\u00e0y, c\u00e1c gia \u0111\u00ecnh c\u00f3 th\u1ec3 b\u1ecb b\u1ecf qua n\u1ebfu quy tr\u00ecnh s\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh \u1edf n\u01a1i h\u1ecd s\u1ed1ng kh\u00f4ng m\u1ea1nh.<\/p>\n

\u0110\u1ec3 gi\u00fap gi\u1ea3i quy\u1ebft nh\u1eefng th\u00e1ch th\u1ee9c n\u00e0y, m\u1ed9t nh\u00f3m c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u1edf B\u1eafc Carolina \u0111\u00e3 ph\u00e1t tri\u1ec3n Early Check<\/a>, m\u1ed9t n\u1ec1n t\u1ea3ng nghi\u00ean c\u1ee9u nh\u1eb1m m\u1ee5c \u0111\u00edch r\u00fat ng\u1eafn th\u1eddi gian \u0111\u00e1nh gi\u00e1 c\u00e1c x\u00e9t nghi\u1ec7m m\u1edbi cho NBS v\u00e0 h\u1ed7 tr\u1ee3 nghi\u00ean c\u1ee9u v\u1ec1 c\u00e1c b\u1ec7nh hi\u1ebfm g\u1eb7p [1]. Ho\u1ea1t \u0111\u1ed9ng h\u1ee3p t\u00e1c v\u1edbi ch\u01b0\u01a1ng tr\u00ecnh s\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh c\u1ee7a ti\u1ec3u bang v\u00e0 c\u00e1c \u0111\u1ed1i t\u00e1c \u0111\u1ea1i h\u1ecdc \u1edf \u0111\u1ecba ph\u01b0\u01a1ng, ch\u01b0\u01a1ng tr\u00ecnh n\u00e0y hi\u1ec7n \u0111\u01b0\u1ee3c cung c\u1ea5p cho c\u00e1c gia \u0111\u00ecnh nh\u01b0 m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u kh\u00f4ng b\u1eaft bu\u1ed9c b\u1ed5 tr\u1ee3 cho c\u00e1c quy tr\u00ecnh NBS ti\u00eau chu\u1ea9n c\u1ee7a ti\u1ec3u bang.<\/p>\n

Lab Insights g\u1ea7n \u0111\u00e2y \u0111\u00e3 trao \u0111\u1ed5i v\u1edbi hai \u0111\u1ea1i di\u1ec7n c\u1ee7a ch\u01b0\u01a1ng tr\u00ecnh Early Check, nh\u1eefng ng\u01b0\u1eddi \u0111\u00e3 n\u00eau b\u1eadt m\u1ed9t s\u1ed1 c\u00e2n nh\u1eafc quan tr\u1ecdng c\u1ea7n thi\u1ebft cho m\u1ecdi n\u1ed7 l\u1ef1c v\u1ec1 NBS.<\/p>\n

\u0110\u00e1nh gi\u00e1 l\u1ee3i \u00edch c\u1ee7a vi\u1ec7c ph\u00e1t hi\u1ec7n s\u1edbm<\/h3>\n

\u0110\u1ec3 b\u1ea5t k\u1ef3 t\u00ecnh tr\u1ea1ng n\u00e0o \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc trong nghi\u00ean c\u1ee9u Early Check, m\u1ed9t trong nh\u1eefng \u0111i\u1ec1u c\u1ea7n c\u00e2n nh\u1eafc \u0111\u1ea7u ti\u00ean l\u00e0 li\u1ec7u \u0111\u00e3 c\u00f3 x\u00e9t nghi\u1ec7m \u0111\u00e1ng tin c\u1eady \u0111\u1ec3 x\u00e9t nghi\u1ec7m cho t\u00ecnh tr\u1ea1ng \u0111\u00f3 hay kh\u00f4ng. \u0110\u1ec3 \u0111\u1ea3m b\u1ea3o th\u1eddi gian tri\u1ec3n khai \u0111\u01b0\u1ee3c r\u00fat ng\u1eafn nh\u1ea5t c\u00f3 th\u1ec3, ch\u01b0\u01a1ng tr\u00ecnh t\u1eadp trung ch\u1ee7 y\u1ebfu v\u00e0o vi\u1ec7c \u0111\u00e1nh gi\u00e1, x\u00e1c th\u1ef1c v\u00e0 tri\u1ec3n khai c\u00e1c x\u00e9t nghi\u1ec7m hi\u1ec7n c\u00f3, thay v\u00ec ph\u00e1t tri\u1ec3n x\u00e9t nghi\u1ec7m.<\/p>\n

Bs. Katerina\u00a0(Kate) Kucera, gi\u00e1m \u0111\u1ed1c ph\u00f2ng x\u00e9t nghi\u1ec7m ch\u01b0\u01a1ng tr\u00ecnh Early Check t\u1ea1i RTI International, cho bi\u1ebft: \u201cCh\u00fang ta ph\u1ea3i hi\u1ec3u r\u00f5 b\u1ed1i c\u1ea3nh khoa h\u1ecdc x\u00e9t nghi\u1ec7m v\u00e0 hi\u1ec3u x\u00e9t nghi\u1ec7m n\u00e0o c\u00f3 th\u1ec3 \u0111\u00e3 s\u1eb5n s\u00e0ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 cho \u00e1p d\u1ee5ng trong s\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh.\u201d \u201cM\u1ed9t s\u1ed1 t\u00ecnh tr\u1ea1ng hi\u1ec7n t\u1ea1i kh\u00f4ng ph\u1ea3i l\u00e0 \u1ee9ng c\u1eed vi\u00ean l\u00fd t\u01b0\u1edfng cho NBS ch\u1ee7 y\u1ebfu v\u00ec kh\u00f4ng c\u00f3 x\u00e9t nghi\u1ec7m n\u00e0o c\u00f3 s\u1eb5n.\u201d<\/p>\n

M\u1ed9t \u0111i\u1ec1u c\u1ea7n c\u00e2n nh\u1eafc n\u1eefa l\u00e0 li\u1ec7u tr\u1ebb em v\u00e0 gia \u0111\u00ecnh cu\u1ed1i c\u00f9ng c\u00f3 \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i t\u1eeb vi\u1ec7c ch\u1ea9n \u0111o\u00e1n s\u1edbm hay kh\u00f4ng. Ngay c\u1ea3 khi m\u1ed9t c\u0103n b\u1ec7nh c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n ch\u00ednh x\u00e1c v\u00e0 hi\u1ec7u qu\u1ea3 v\u1ec1 chi ph\u00ed, vi\u1ec7c ph\u00e1t hi\u1ec7n s\u1edbm c\u00f3 th\u1ec3 mang l\u1ea1i l\u1ee3i \u00edch h\u1ea1n ch\u1ebf n\u1ebfu kh\u00f4ng c\u00f3 li\u1ec7u ph\u00e1p ho\u1eb7c can thi\u1ec7p n\u00e0o c\u00f3 s\u1eb5n \u0111\u1ec3 thay \u0111\u1ed5i xu h\u01b0\u1edbng ph\u00e1t tri\u1ec3n c\u1ee7a b\u1ec7nh.<\/p>\n

Gi\u1ea3 s\u1eed c\u00f3 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ho\u1eb7c can thi\u1ec7p th\u00ec ph\u1ea3i c\u00f3 \u0111\u1ee7 ngu\u1ed3n l\u1ef1c \u0111\u1ec3 chu\u1ea9n b\u1ecb cho tr\u01b0\u1eddng h\u1ee3p tr\u1ebb s\u01a1 sinh c\u00f3 k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m d\u01b0\u01a1ng t\u00ednh trong qu\u00e1 tr\u00ecnh s\u00e0ng l\u1ecdc. Trong ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u Early Check, n\u1ebfu c\u00f3 k\u1ebft qu\u1ea3 nghi\u00ean c\u1ee9u d\u01b0\u01a1ng t\u00ednh th\u00ec m\u1ed9t s\u1ed1 h\u00e0nh \u0111\u1ed9ng sau \u0111\u00e2y s\u1ebd \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n: th\u00f4ng b\u00e1o ban \u0111\u1ea7u cho gia \u0111\u00ecnh, theo d\u00f5i t\u1eeb chuy\u00ean gia t\u01b0 v\u1ea5n di truy\u1ec1n, x\u00e9t nghi\u1ec7m x\u00e1c nh\u1eadn t\u00ecnh tr\u1ea1ng b\u1ec7nh v\u00e0 k\u1ebft n\u1ed1i v\u1edbi c\u00e1c chuy\u00ean gia l\u00e2m s\u00e0ng ho\u1eb7c chuy\u00ean gia v\u1ec1 h\u00e0nh vi c\u00f3 th\u1ec3 gi\u00fap gia \u0111\u00ecnh v\u1ec1 t\u00ecnh tr\u1ea1ng b\u1ec7nh c\u1ee5 th\u1ec3 \u0111\u00f3.<\/p>\n

Khi ra m\u1eaft, nh\u00f3m Early Check \u0111\u00e3 ch\u1ecdn h\u1ed9i ch\u1ee9ng g\u00e3y nhi\u1ec5m s\u1eafc th\u1ec3 X (FXS) v\u00e0 teo c\u01a1 t\u1ee7y (SMA), hai t\u00ecnh tr\u1ea1ng kh\u00f4ng \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o s\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh v\u00e0o th\u1eddi \u0111i\u1ec3m \u0111\u00f3 nh\u01b0ng can thi\u1ec7p s\u1edbm \u0111\u1ed1i v\u1edbi nh\u1eefng t\u00ecnh tr\u1ea1ng n\u00e0y c\u00f3 th\u1ec3 t\u1ea1o ra s\u1ef1 kh\u00e1c bi\u1ec7t th\u1ef1c s\u1ef1 trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u1ee7a tr\u1ebb. \u0110\u00e1nh gi\u00e1 c\u1ee7a h\u1ecd v\u1ec1 SMA [2] v\u00e0 FXS [3] hi\u1ec7n \u0111\u00e3 ho\u00e0n t\u1ea5t.<\/p>\n

Hi\u1ec7n t\u1ea1i, nh\u00f3m \u0111ang s\u00e0ng l\u1ecdc b\u1ec7nh lo\u1ea1n d\u01b0\u1ee1ng c\u01a1 Duchenne (DMD) v\u00e0 c\u00e1c t\u00ecnh tr\u1ea1ng li\u00ean quan, \u0111\u1ed3ng th\u1eddi \u0111ang c\u00f3 k\u1ebf ho\u1ea1ch tri\u1ec3n khai m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u m\u1edbi t\u1eadp trung v\u00e0o ba r\u1ed1i lo\u1ea1n in d\u1ea5u nhi\u1ec5m s\u1eafc th\u1ec3 15 \u2013 h\u1ed9i ch\u1ee9ng Angelman, h\u1ed9i ch\u1ee9ng Prader-Willi v\u00e0 Dup15q<\/a>. Nh\u00f3m c\u0169ng \u0111ang kh\u00e1m ph\u00e1 ti\u1ec1m n\u0103ng \u1ee9ng d\u1ee5ng c\u1ee7a gi\u1ea3i tr\u00ecnh t\u1ef1 b\u1ed9 gen trong s\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh.<\/p>\n

Bs. Anne Wheeler, chuy\u00ean gia ph\u00e2n t\u00edch y t\u1ebf c\u00f4ng c\u1ed9ng t\u1ea1i RTI International v\u00e0 l\u00e0 th\u00e0nh vi\u00ean c\u1ee7a ch\u01b0\u01a1ng tr\u00ecnh Early Check, ng\u01b0\u1eddi \u0111\u00e3 d\u00e0nh nhi\u1ec1u n\u0103m \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n Angelman v\u1edbi t\u01b0 c\u00e1ch l\u00e0 nh\u00e0 t\u00e2m l\u00fd h\u1ecdc, cho bi\u1ebft: \u201cCh\u00fang ta c\u1ea7n ch\u1ea9n \u0111o\u00e1n s\u1edbm h\u01a1n \u0111\u1ec3 c\u00f3 th\u1ec3 mang l\u1ea1i l\u1ee3i \u00edch t\u1ed1i \u0111a cho b\u1ec7nh nh\u00e2n m\u1eafc h\u1ed9i ch\u1ee9ng Angelman\u201d. Ngo\u00e0i ra, c\u00f2n c\u00f3 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111ang \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n cho c\u00e1c r\u1ed1i lo\u1ea1n nhi\u1ec5m s\u1eafc th\u1ec3 15 khi\u1ebfn vi\u1ec7c ch\u1ea9n \u0111o\u00e1n s\u1edbm tr\u1edf n\u00ean quan tr\u1ecdng h\u01a1n n\u1eefa.<\/p>\n

C\u00e1c v\u1ea5n \u0111\u1ec1 h\u1eadu c\u1ea7n then ch\u1ed1t l\u00e0 g\u00ec?<\/h3>\n

Khi \u0111\u00e3 l\u1ef1a ch\u1ecdn c\u00e1c t\u00ecnh tr\u1ea1ng v\u00e0 t\u1eadp h\u1ee3p ngu\u1ed3n l\u1ef1c \u0111\u1ec3 x\u1eed l\u00fd c\u00e1c tr\u01b0\u1eddng h\u1ee3p d\u01b0\u01a1ng t\u00ednh, ph\u1ea7n c\u00f2n l\u1ea1i c\u1ee7a ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u Early Check s\u1ebd l\u00e0 v\u1ea5n \u0111\u1ec1 h\u1eadu c\u1ea7n. V\u00ed d\u1ee5: khi \u0111\u00e1nh gi\u00e1 m\u1ed9t x\u00e9t nghi\u1ec7m, nh\u00f3m Early Check ph\u1ea3i c\u00e2n nh\u1eafc kh\u00f4ng ch\u1ec9 \u0111\u1ed9 ch\u00ednh x\u00e1c v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng m\u00e0 c\u00f2n c\u1ea3 chi ph\u00ed v\u00e0 t\u00ednh d\u1ec5 s\u1eed d\u1ee5ng \u2013 li\u1ec7u \u0111\u00e2y c\u00f3 ph\u1ea3i l\u00e0 x\u00e9t nghi\u1ec7m c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng r\u1ed9ng r\u00e3i b\u1edfi c\u00e1c ph\u00f2ng x\u00e9t nghi\u1ec7m th\u1ef1c hi\u1ec7n s\u00e0ng l\u1ecdc th\u01b0\u1eddng quy cho tr\u1ebb s\u01a1 sinh kh\u00f4ng?<\/p>\n

\u0110\u1ec3 gi\u1ea3i quy\u1ebft v\u1ea5n \u0111\u1ec1 chi ph\u00ed, h\u1ecd r\u1ea5t quan t\u00e2m \u0111\u1ebfn vi\u1ec7c x\u00e9t nghi\u1ec7m \u0111a m\u1ed3i. H\u1ecd c\u0169ng \u0111ang nghi\u00ean c\u1ee9u v\u1ec1 gi\u1ea3i tr\u00ecnh t\u1ef1 b\u1ed9 gen, \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 m\u1edf ra c\u00e1nh c\u1eeda \u0111\u1ec3 x\u00e9t nghi\u1ec7m nhi\u1ec1u t\u00ecnh tr\u1ea1ng m\u00e0 kh\u00f4ng c\u00f3 x\u00e9t nghi\u1ec7m n\u00e0o kh\u00e1c c\u00f3 s\u1eb5n. C\u1ea3 hai ph\u01b0\u01a1ng ph\u00e1p ti\u1ebfp c\u1eadn \u0111\u1ec1u c\u00f3 th\u1ec3 cho ph\u00e9p h\u1ecd t\u00ecm ra nhi\u1ec1u c\u00e2u tr\u1ea3 l\u1eddi h\u01a1n t\u1eeb c\u00e1c m\u1eabu \u0111\u1ed1m m\u00e1u kh\u00f4 m\u00e0 h\u1ecd s\u1eed d\u1ee5ng.<\/p>\n

Bs. Wheeler l\u01b0u \u00fd: \u201cB\u1ea1n c\u00e0ng c\u00f3 nhi\u1ec1u x\u00e9t nghi\u1ec7m cho c\u00e1c t\u00ecnh tr\u1ea1ng kh\u00e1c nhau th\u00ec b\u1ea1n c\u00e0ng c\u1ea7n nhi\u1ec1u m\u1eabu m\u00e1u\u201d. \u0110\u1ea3m b\u1ea3o quy tr\u00ecnh l\u1ea5y m\u1eabu nhanh ch\u00f3ng v\u00e0 \u0111\u00e1ng tin c\u1eady t\u1eeb b\u1ec7nh vi\u1ec7n \u0111\u1ebfn ph\u00f2ng x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc c\u0169ng r\u1ea5t c\u1ea7n thi\u1ebft.<\/p>\n

T\u1ea5t nhi\u00ean, ngu\u1ed3n t\u00e0i tr\u1ee3 c\u0169ng quan tr\u1ecdng. B\u1ea5t k\u1ef3 nghi\u00ean c\u1ee9u n\u00e0o c\u0169ng c\u1ea7n ngu\u1ed3n t\u00e0i tr\u1ee3 \u1ed5n \u0111\u1ecbnh \u0111\u1ec3 h\u1ed7 tr\u1ee3 c\u00f4ng vi\u1ec7c trong ph\u00f2ng x\u00e9t nghi\u1ec7m, x\u00e9t nghi\u1ec7m theo d\u00f5i, ph\u1ed5 bi\u1ebfn ki\u1ebfn th\u1ee9c cho gia \u0111\u00ecnh, v.v. Bs. Kucera cho bi\u1ebft: \u201cC\u00f3 r\u1ea5t nhi\u1ec1u s\u1ef1 h\u00e0o h\u1ee9ng v\u1ec1 t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c x\u00e1c \u0111\u1ecbnh s\u1edbm, tuy nhi\u00ean, vi\u1ec7c t\u1eadp h\u1ee3p t\u1ea5t c\u1ea3 c\u00e1c b\u00ean li\u00ean quan l\u1ea1i v\u1edbi nhau v\u00e0 t\u1ea1o ra m\u1ed9t m\u1ee5c ti\u00eau chung cho m\u1ed9t nghi\u00ean c\u1ee9u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c t\u00e0i tr\u1ee3 lu\u00f4n l\u00e0 \u0111i\u1ec1u m\u00e0 ch\u00fang t\u00f4i coi l\u00e0 m\u1ed9t th\u00e1ch th\u1ee9c\u201d.<\/p>\n

V\u1edbi c\u00e1c li\u1ec7u ph\u00e1p m\u1edbi \u0111\u1ea7y ph\u1ea5n kh\u1edfi cho nhi\u1ec1u b\u1ec7nh hi\u1ebfm g\u1eb7p \u0111ang xu\u1ea5t hi\u1ec7n, c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh NBS c\u1ee7a ti\u1ec3u bang s\u1ebd ti\u1ebfp t\u1ee5c \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n theo th\u1eddi gian, kh\u00f4ng ch\u1ec9 v\u1ec1 ph\u1ea1m vi m\u00e0 c\u00f2n v\u1ec1 ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 chi ph\u00ed. B\u1eb1ng c\u00e1ch t\u1ea1o ra b\u1eb1ng ch\u1ee9ng ch\u1ea5t l\u01b0\u1ee3ng cao v\u1ec1 hi\u1ec7u qu\u1ea3 c\u1ee7a c\u00e1c x\u00e9t nghi\u1ec7m m\u1edbi, ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u Early Check \u0111ang c\u00f3 nh\u1eefng \u0111\u00f3ng g\u00f3p quan tr\u1ecdng cho ti\u1ebfn tr\u00ecnh n\u00e0y.<\/p>\n

T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/em><\/p>\n

[1]<\/a> Bailey, D., Gehtland, L., Lewis, M., Peay, H., Raspa, M., Shone, S., Taylor, J., Wheeler, A., Cotten, M., King, N., Powell, C., Biesecker, B., Bishop, C., Boyea, B., Duparc, M., Harper, B., Kemper, A., Lee, S., Moultrie, R., Okoniewski, K., Paquin, R., Pettit, D., Porter, K. and Zimmerman, S., 2019. Early Check: translational science at the intersection of public health and newborn screening. BMC Pediatrics, 19(1). Truy c\u1eadp t\u1ea1i: <https:\/\/bmcpediatr.biomedcentral.com\/articles\/10.1186\/s12887-019-1606-4><\/p>\n

[2]<\/a> Kucera, K., Taylor, J., Robles, V., Clinard, K., Migliore, B., Boyea, B., Okoniewski, K., Duparc, M., Rehder, C., Shone, S., Fan, Z., Raspa, M., Peay, H., Wheeler, A., Powell, C., Bailey, D. and Gehtland, L., 2021. A Voluntary Statewide Newborn Screening Pilot for Spinal Muscular Atrophy: Results from Early Check. International Journal of Neonatal Screening, 7(1), p.20. Truy c\u1eadp t\u1ea1i:<https:\/\/www.mdpi.com\/2409-515X\/7\/1\/20><\/p>\n

[3]<\/a> Okoniewski, K., Wheeler, A., Lee, S., Boyea, B., Raspa, M., Taylor, J. and Bailey, D., 2019. Early Identification of Fragile X Syndrome through Expanded Newborn Screening. Brain Sciences, 9(1), p.4. Truy c\u1eadp t\u1ea1i:<https:\/\/www.mdpi.com\/2076-3425\/9\/1\/4><\/p>\n","protected":false},"excerpt":{"rendered":"

  S\u00e0ng l\u1ecdc cho tr\u1ebb s\u01a1 sinh (NBS) l\u00e0 m\u1ed9t c\u00f4ng c\u1ee5 quan tr\u1ecdng \u0111\u1ec3 c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe con ng\u01b0\u1eddi, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u0111\u1ed1i v\u1edbi tr\u1ebb em m\u1eafc b\u1ec7nh hi\u1ebfm g\u1eb7p, nh\u1eefng tr\u1ebb c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i t\u1eeb vi\u1ec7c can thi\u1ec7p s\u1edbm. Tuy nhi\u00ean, \u1edf nhi\u1ec1u qu\u1ed1c gia, c\u00f3 th\u1ec3 m\u1ea5t nhi\u1ec1u n\u0103m […]<\/p>\n","protected":false},"author":1,"featured_media":85453,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"tags":[],"pillarandcategory":[293,282,294],"reporter":[14945,14944],"class_list":["post-147098","acf_article","type-acf_article","status-publish","has-post-thumbnail","hentry","pillarandcategory-newborn-screening","pillarandcategory-disease-area","pillarandcategory-rare-diseases","reporter-anne-wheeler","reporter-katerina-kucera"],"acf":[],"_links":{"self":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147098","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article"}],"about":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/types\/acf_article"}],"author":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":3,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147098\/revisions"}],"predecessor-version":[{"id":149102,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147098\/revisions\/149102"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media\/85453"}],"wp:attachment":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media?parent=147098"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/tags?post=147098"},{"taxonomy":"pillarandcategory","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/pillarandcategory?post=147098"},{"taxonomy":"reporter","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/reporter?post=147098"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}