{"id":147173,"date":"2023-11-19T06:26:36","date_gmt":"2023-11-19T06:26:36","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/khong-the-chan-doan-duoc-mang-luoi-nghien-cuu-lam-sang-nay-co-the-giup-duoc\/"},"modified":"2026-01-27T08:51:36","modified_gmt":"2026-01-27T08:51:36","slug":"undiagnosable-this-clinical-research-network-can-help","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/vi\/disease-area\/rare-diseases\/undiagnosable-this-clinical-research-network-can-help\/","title":{"rendered":"Kh\u00f4ng th\u1ec3 ch\u1ea9n \u0111o\u00e1n \u0111\u01b0\u1ee3c? M\u1ea1ng l\u01b0\u1edbi nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng n\u00e0y c\u00f3 th\u1ec3 gi\u00fap \u0111\u01b0\u1ee3c"},"content":{"rendered":"

Cho \u0111\u1ebfn th\u1eddi gian g\u1ea7n \u0111\u00e2y, vi\u1ec7c m\u1eafc m\u1ed9t b\u1ec7nh hi\u1ebfm g\u1eb7p ho\u1eb7c ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n h\u1ea7u nh\u01b0 \u0111\u1ed3ng ngh\u0129a v\u1edbi vi\u1ec7c ng\u01b0\u1eddi b\u1ec7nh ph\u1ea3i tr\u1ea3i qua m\u1ed9t h\u00e0nh tr\u00ecnh ch\u1ea9n \u0111o\u00e1n k\u00e9o d\u00e0i nhi\u1ec1u n\u0103m, ch\u1ecbu \u0111\u1ef1ng h\u00e0ng lo\u1ea1t x\u00e9t nghi\u1ec7m t\u1ed1n k\u00e9m m\u00e0 g\u1ea7n nh\u01b0 kh\u00f4ng c\u00f3 hy v\u1ecdng t\u00ecm \u0111\u01b0\u1ee3c c\u00e2u tr\u1ea3 l\u1eddi. M\u1eb7c d\u00f9 t\u00ecnh c\u1ea3nh \u0111\u00f3 v\u1eabn c\u00f2n l\u00e0 \u0111i\u1ec1u kh\u00f4ng th\u1ec3 tr\u00e1nh kh\u1ecfi \u0111\u1ed1i v\u1edbi m\u1ed9t s\u1ed1 ng\u01b0\u1eddi, nh\u01b0ng vi\u1ec7c m\u1edf r\u1ed9ng kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn c\u00e1c ph\u01b0\u01a1ng ph\u00e1p gi\u1ea3i tr\u00ecnh t\u1ef1 to\u00e0n di\u1ec7n v\u1edbi chi ph\u00ed ph\u1ea3i ch\u0103ng \u0111\u00e3 l\u00e0m thay \u0111\u1ed5i ho\u00e0n to\u00e0n tri\u1ec3n v\u1ecdng \u0111\u1ea1t \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n.<\/p>\n

Lo\u1ea1i c\u00f4ng vi\u1ec7c n\u00e0y \u0111ang di\u1ec5n ra tr\u00ean kh\u1eafp th\u1ebf gi\u1edbi, nh\u01b0ng m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh ho\u1ea1t \u0111\u1ed9ng l\u00e2u n\u0103m t\u1ea1i Hoa K\u1ef3 cho th\u1ea5y v\u00ed d\u1ee5 v\u1ec1 m\u1ee9c \u0111\u1ed9 \u1ea3nh h\u01b0\u1edfng m\u00e0 c\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y c\u00f3 th\u1ec3 mang l\u1ea1i. Ra m\u1eaft v\u00e0o n\u0103m 2008 b\u1edfi Vi\u1ec7n Y t\u1ebf Qu\u1ed1c gia Hoa K\u1ef3, M\u1ea1ng l\u01b0\u1edbi b\u1ec7nh l\u00fd ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n<\/a> (Undiagnosed Diseases Network, UDN) cung c\u1ea5p c\u00e1c ngu\u1ed3n l\u1ef1c ch\u1ea9n \u0111o\u00e1n quan tr\u1ecdng cho nh\u1eefng c\u00e1 nh\u00e2n v\u00e0 gia \u0111\u00ecnh m\u1eafc c\u00e1c b\u1ec7nh c\u1ef1c k\u1ef3 hi\u1ebfm ho\u1eb7c ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n. Ch\u01b0\u01a1ng tr\u00ecnh h\u1ee3p t\u00e1c v\u1edbi M\u1ea1ng l\u01b0\u1edbi qu\u1ed1c t\u1ebf v\u1ec1 b\u1ec7nh l\u00fd ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n<\/a> \u0111\u1ec3 m\u1edf r\u1ed9ng c\u00e1c ngu\u1ed3n l\u1ef1c n\u00e0y \u0111\u1ebfn b\u1ec7nh nh\u00e2n, b\u00e1c s\u0129 v\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng tr\u00ean to\u00e0n th\u1ebf gi\u1edbi.<\/p>\n

T\u1ea1i Hoa K\u1ef3, m\u1ea1ng l\u01b0\u1edbi n\u00e0y bao g\u1ed3m g\u1ea7n 20 c\u01a1 s\u1edf l\u00e2m s\u00e0ng t\u1ea1i c\u00e1c trung t\u00e2m y khoa h\u1ecdc thu\u1eadt, n\u01a1i c\u00e1c nh\u00e0 khoa h\u1ecdc v\u00e0 nh\u00e0 nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng l\u00e0m vi\u1ec7c tr\u1ef1c ti\u1ebfp v\u1edbi ng\u01b0\u1eddi tham gia v\u00e0 gia \u0111\u00ecnh c\u1ee7a h\u1ecd. H\u01a1n 2.000 ng\u01b0\u1eddi tham gia \u0111\u00e3 \u0111\u01b0\u1ee3c ghi danh k\u1ec3 t\u1eeb khi ch\u01b0\u01a1ng tr\u00ecnh b\u1eaft \u0111\u1ea7u, v\u00e0 g\u1ea7n 700 ng\u01b0\u1eddi \u0111\u00e3 nh\u1eadn \u0111\u01b0\u1ee3c \u00edt nh\u1ea5t m\u1ed9t ch\u1ea9n \u0111o\u00e1n \u0111\u01b0\u1ee3c x\u00e1c nh\u1eadn ho\u1eb7c c\u00f3 kh\u1ea3 n\u0103ng cao. T\u1ef7 l\u1ec7 th\u00e0nh c\u00f4ng c\u1ee7a nh\u1eefng ca ph\u1eabu thu\u1eadt kh\u00f3 kh\u0103n nh\u1ea5t tr\u00ean th\u1ebf gi\u1edbi l\u00e0 h\u01a1n 30%.<\/p>\n

Ph\u1ea7n l\u1edbn (h\u01a1n 80%) c\u00e1c ch\u1ea9n \u0111o\u00e1n n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1eb1ng c\u00e1ch gi\u1ea3i tr\u00ecnh t\u1ef1 to\u00e0n b\u1ed9 b\u1ed9 h\u1ec7 gen ho\u1eb7c to\u00e0n b\u1ed9 exome, v\u1edbi nh\u1eefng \u0111\u00f3ng g\u00f3p nh\u1ecf h\u01a1n t\u1eeb c\u00e1c x\u00e9t nghi\u1ec7m l\u00e2m s\u00e0ng tr\u1ef1c ti\u1ebfp, vi m\u1ea3ng nhi\u1ec5m s\u1eafc th\u1ec3, karyotyping v\u00e0 c\u00e1c k\u1ef9 thu\u1eadt kh\u00e1c. C\u00e1c tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng ph\u1ed5 bi\u1ebfn nh\u1ea5t, xu\u1ea5t hi\u1ec7n \u1edf kho\u1ea3ng 40% b\u1ec7nh nh\u00e2n, l\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng v\u1ec1 th\u1ea7n kinh.<\/p>\n

C\u00f3 l\u1ebd \u0111i\u1ec1u \u0111\u00e1ng ch\u00fa \u00fd nh\u1ea5t l\u00e0 nh\u1eefng n\u1ed7 l\u1ef1c c\u1ee7a m\u1ea1ng l\u01b0\u1edbi \u0111\u00e3 d\u1eabn \u0111\u1ebfn vi\u1ec7c ph\u00e1t hi\u1ec7n h\u01a1n 60 b\u1ec7nh l\u00fd m\u1edbi, qua \u0111\u00f3 m\u1edf ra kh\u1ea3 n\u0103ng ph\u00e1t tri\u1ec3n c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n b\u1ec7nh hi\u1ebfm g\u1eb7p m\u1edbi \u0111\u1ec3 gi\u00fap nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00e1c c\u0169ng \u0111ang m\u1eafc ph\u1ea3i c\u00e1c t\u00ecnh tr\u1ea1ng tr\u01b0\u1edbc \u0111\u00e2y v\u1ed1n \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng th\u1ec3 ch\u1ea9n \u0111o\u00e1n.<\/p>\n

\u0110\u1ea7u n\u0103m nay, Qu\u1ef9 M\u1ea1ng l\u01b0\u1edbi b\u1ec7nh l\u00fd ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n (Undiagnosed Diseases Network Foundation, UDNF<\/a>) \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u01b0a ra \u0111\u1ec3 h\u1ed7 tr\u1ee3 t\u00e0i ch\u00ednh phi ch\u00ednh ph\u1ee7 nh\u1eb1m \u0111\u1ea3m b\u1ea3o kh\u1ea3 n\u0103ng t\u1ed3n t\u1ea1i l\u00e2u d\u00e0i c\u1ee7a m\u1ea1ng l\u01b0\u1edbi. Lab Insights \u0111\u00e3 tr\u00f2 chuy\u1ec7n v\u1edbi Amy Gray, Gi\u00e1m \u0111\u1ed1c \u0111i\u1ec1u h\u00e0nh \u0111\u1ea7u ti\u00ean c\u1ee7a t\u1ed5 ch\u1ee9c, \u0111\u1ec3 t\u00ecm hi\u1ec3u th\u00eam.<\/p>\n

T\u1ea1i sao c\u1ea7n c\u00f3 t\u1ed5 ch\u1ee9c n\u00e0y?<\/h2>\n

AG: M\u1ea1ng l\u01b0\u1edbi b\u1ec7nh l\u00fd ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n l\u00e0 m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh th\u1ef1c s\u1ef1 n\u1ed5i b\u1eadt; \u0111\u00e2y l\u00e0 m\u1ed9t trong nh\u1eefng ch\u01b0\u01a1ng tr\u00ecnh th\u00e0nh c\u00f4ng nh\u1ea5t m\u00e0 NIH t\u1eebng tri\u1ec3n khai. \u00dd t\u01b0\u1edfng v\u1ec1 m\u1ed9t qu\u1ef9 do b\u1ec7nh nh\u00e2n d\u1eabn d\u1eaft nh\u1eb1m h\u1ed7 tr\u1ee3 m\u1ea1ng l\u01b0\u1edbi xu\u1ea5t ph\u00e1t t\u1eeb ch\u00ednh c\u00e1c b\u1ec7nh nh\u00e2n, b\u00e1c s\u0129, nh\u00e0 nghi\u00ean c\u1ee9u v\u00e0 c\u00e1c b\u00ean li\u00ean quan kh\u00e1c \u2014 h\u1ecd l\u00e0 ng\u01b0\u1eddi mu\u1ed1n \u0111\u1ea3m b\u1ea3o ch\u01b0\u01a1ng tr\u00ecnh n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c duy tr\u00ec v\u00e0 ti\u1ebfp t\u1ee5c ph\u00e1t tri\u1ec3n ngay c\u1ea3 khi ngu\u1ed3n t\u00e0i tr\u1ee3 t\u1eeb NIH k\u1ebft th\u00fac.<\/p>\n

Ch\u00fang t\u00f4i c\u0169ng mu\u1ed1n h\u1ed7 tr\u1ee3 c\u1ed9ng \u0111\u1ed3ng nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n v\u00e0 b\u1ec7nh c\u1ef1c hi\u1ebfm \u2014 nh\u00f3m b\u1ec7nh nh\u00e2n n\u00e0y c\u00f3 th\u1ec3 kh\u00f4ng c\u00f3 nhi\u1ec1u ngu\u1ed3n l\u1ef1c kh\u00e1c c\u00f3 th\u1ec3 t\u00ecm \u0111\u1ebfn. T\u00f4i \u0111\u00e3 l\u00e0m vi\u1ec7c trong l\u0129nh v\u1ef1c t\u1eeb thi\u1ec7n y t\u1ebf phi l\u1ee3i nhu\u1eadn trong nhi\u1ec1u l\u0129nh v\u1ef1c b\u1ec7nh hi\u1ebfm g\u1eb7p, v\u00e0 ch\u01b0a bao gi\u1edd t\u1ed3n t\u1ea1i m\u1ed9t t\u1ed5 ch\u1ee9c n\u00e0o d\u00e0nh cho nh\u1eefng ng\u01b0\u1eddi ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh ch\u1ea9n \u0111o\u00e1n. Nhu c\u1ea7u d\u00e0nh cho \u0111i\u1ec1u \u0111\u00f3 l\u00e0 v\u00f4 c\u00f9ng l\u1edbn, v\u00e0 t\u1ed5 ch\u1ee9c n\u00e0y ra \u0111\u1eddi \u0111\u1ec3 \u0111\u00e1p \u1ee9ng nhu c\u1ea7u \u1ea5y.<\/p>\n

Vi\u1ec7c c\u00f3 th\u1ec3 ti\u1ebfp c\u1eadn m\u1ed9t c\u1ed9ng \u0111\u1ed3ng nh\u01b0 th\u1ebf n\u00e0y s\u1ebd t\u1ea1o ra s\u1ef1 kh\u00e1c bi\u1ec7t nh\u01b0 th\u1ebf n\u00e0o \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n?<\/h2>\n

AG: N\u1ebfu kh\u00f4ng c\u00f3 t\u1ed5 ch\u1ee9c n\u00e0y, c\u00e1c gia \u0111\u00ecnh s\u1ebd ph\u1ea3i t\u1ef1 m\u00ecnh v\u01b0\u1ee3t qua h\u00e0nh tr\u00ecnh gian kh\u00f3 n\u00e0y. Khi ch\u00fang t\u00f4i t\u1eadp h\u1ee3p m\u1ed9t nh\u00f3m c\u00e1c b\u00ean li\u00ean quan \u0111\u1ec3 th\u1ea3o lu\u1eadn v\u1ec1 k\u1ebf ho\u1ea1ch cho t\u1ed5 ch\u1ee9c, \u0111i\u1ec1u r\u1ea5t r\u00f5 r\u00e0ng l\u00e0 c\u00e1c gia \u0111\u00ecnh mu\u1ed1n c\u00f3 m\u1ed9t n\u01a1i \u0111\u1ec3 h\u1ecd v\u00e0 nh\u1eefng ng\u01b0\u1eddi kh\u00e1c c\u00f3 th\u1ec3 t\u00ecm \u0111\u1ebfn \u2014 m\u1ed9t c\u1ed9ng \u0111\u1ed3ng h\u1ed7 tr\u1ee3 \u0111\u1ec3 kh\u00f4ng ai ph\u1ea3i \u0111i tr\u00ean h\u00e0nh tr\u00ecnh n\u00e0y m\u1ed9t m\u00ecnh.<\/p>\n

M\u1ed9t trong nh\u1eefng ch\u01b0\u01a1ng tr\u00ecnh \u0111\u1ea7u ti\u00ean m\u00e0 ch\u00fang t\u00f4i s\u1ebd tri\u1ec3n khai l\u00e0 ch\u01b0\u01a1ng tr\u00ecnh h\u1ed7 tr\u1ee3 \u0111\u1ecbnh h\u01b0\u1edbng cho b\u1ec7nh nh\u00e2n v\u00e0 gia \u0111\u00ecnh, gi\u00fap h\u1ecd \u0111\u01b0\u1ee3c h\u01b0\u1edbng d\u1eabn tr\u00ean h\u00e0nh tr\u00ecnh x\u00e1c \u0111\u1ecbnh ch\u1ea9n \u0111o\u00e1n v\u00e0 sau \u0111\u00f3 ti\u1ebfp c\u1eadn c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb c\u00f9ng nhi\u1ec1u h\u1ed7 tr\u1ee3 kh\u00e1c. Ch\u00fang t\u00f4i bi\u1ebft r\u1eb1ng khi b\u1ea1n t\u1eadp h\u1ee3p m\u1ed9t nh\u00f3m ph\u1ee5 huynh v\u00e0 gia \u0111\u00ecnh l\u1ea1i v\u1edbi nhau, h\u1ecd s\u1ebd tr\u1edf n\u00ean v\u00f4 c\u00f9ng m\u1ea1nh m\u1ebd v\u00e0 kh\u00f4ng g\u00ec c\u00f3 th\u1ec3 ng\u0103n c\u1ea3n h\u1ecd. Ch\u00fang t\u00f4i th\u1ef1c s\u1ef1 mu\u1ed1n t\u1ea1o \u0111i\u1ec1u ki\u1ec7n \u0111\u1ec3 x\u00e2y d\u1ef1ng \u0111\u01b0\u1ee3c m\u1ed9t c\u1ed9ng \u0111\u1ed3ng nh\u01b0 v\u1eady.<\/p>\n

C\u00e1c c\u00f4ng c\u1ee5 ch\u1ea9n \u0111o\u00e1n c\u00f3 th\u1ec3 h\u1ed7 tr\u1ee3 c\u1ed9ng \u0111\u1ed3ng n\u00e0y nh\u01b0 th\u1ebf n\u00e0o?<\/h2>\n

AG: M\u1ed9t ph\u1ea7n quan tr\u1ecdng trong tr\u1ecdng t\u00e2m c\u1ee7a ch\u00fang t\u00f4i l\u00e0 kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn v\u00e0 c\u00f4ng b\u1eb1ng khi n\u00f3i \u0111\u1ebfn c\u00e1c c\u00f4ng ngh\u1ec7 ch\u1ea9n \u0111o\u00e1n, v\u00e0 hi\u1ec7n t\u1ea1i ch\u00fang t\u00f4i \u0111\u1eb7c bi\u1ec7t quan t\u00e2m \u0111\u1ebfn gi\u1ea3i tr\u00ecnh t\u1ef1 to\u00e0n b\u1ed9 h\u1ec7 gen nhanh. Khi c\u00e1c c\u00f4ng ty ch\u1ea9n \u0111o\u00e1n c\u00f3 th\u1ec3 h\u1ee3p t\u00e1c v\u1edbi c\u00e1c t\u1ed5 ch\u1ee9c c\u1ed9ng \u0111\u1ed3ng, \u0111i\u1ec1u \u0111\u00f3 s\u1ebd th\u1ef1c s\u1ef1 quan tr\u1ecdng \u0111\u1ec3 gi\u1ea3i quy\u1ebft c\u00e1c tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh kh\u00f4ng \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n v\u00e0 c\u1ef1c k\u1ef3 hi\u1ebfm g\u1eb7p. Ch\u00fang t\u00f4i hy v\u1ecdng s\u1ebd thi\u1ebft l\u1eadp quan h\u1ec7 \u0111\u1ed1i t\u00e1c v\u1edbi c\u00e1c c\u00f4ng ty ch\u1ea9n \u0111o\u00e1n v\u00e0 gi\u00fap gi\u00e1o d\u1ee5c c\u1ed9ng \u0111\u1ed3ng ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe v\u1ec1 c\u00e1c t\u00f9y ch\u1ecdn ch\u1ea9n \u0111o\u00e1n m\u1edbi khi ch\u00fang xu\u1ea5t hi\u1ec7n.<\/p>\n","protected":false},"excerpt":{"rendered":"

Cho \u0111\u1ebfn th\u1eddi gian g\u1ea7n \u0111\u00e2y, vi\u1ec7c m\u1eafc m\u1ed9t b\u1ec7nh hi\u1ebfm g\u1eb7p ho\u1eb7c ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n h\u1ea7u nh\u01b0 \u0111\u1ed3ng ngh\u0129a v\u1edbi vi\u1ec7c ng\u01b0\u1eddi b\u1ec7nh ph\u1ea3i tr\u1ea3i qua m\u1ed9t h\u00e0nh tr\u00ecnh ch\u1ea9n \u0111o\u00e1n k\u00e9o d\u00e0i nhi\u1ec1u n\u0103m, ch\u1ecbu \u0111\u1ef1ng h\u00e0ng lo\u1ea1t x\u00e9t nghi\u1ec7m t\u1ed1n k\u00e9m m\u00e0 g\u1ea7n nh\u01b0 kh\u00f4ng c\u00f3 hy v\u1ecdng t\u00ecm \u0111\u01b0\u1ee3c c\u00e2u […]<\/p>\n","protected":false},"author":1,"featured_media":85829,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"tags":[14828,14830],"pillarandcategory":[294,282],"reporter":[15018],"class_list":["post-147173","acf_article","type-acf_article","status-publish","has-post-thumbnail","hentry","tag-benh-hiem","tag-hoa-ky","pillarandcategory-rare-diseases","pillarandcategory-disease-area","reporter-amy-gray"],"acf":[],"_links":{"self":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147173","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article"}],"about":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/types\/acf_article"}],"author":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":2,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147173\/revisions"}],"predecessor-version":[{"id":147650,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147173\/revisions\/147650"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media\/85829"}],"wp:attachment":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media?parent=147173"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/tags?post=147173"},{"taxonomy":"pillarandcategory","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/pillarandcategory?post=147173"},{"taxonomy":"reporter","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/reporter?post=147173"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}