Thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch (VTE) ch\u1ec9 c\u00e1c c\u1ee5c m\u00e1u \u0111\u00f4ng ph\u00e1t tri\u1ec3n trong t\u0129nh m\u1ea1ch [1]. Hai bi\u1ec3u hi\u1ec7n ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a VTE l\u00e0 huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT) v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i (PE) [1]. DVT x\u1ea3y ra khi m\u1ed9t c\u1ee5c m\u00e1u \u0111\u00f4ng ph\u00e1t tri\u1ec3n trong m\u1ed9t t\u0129nh m\u1ea1ch s\u00e2u, v\u00e0 PE x\u1ea3y ra khi c\u1ee5c m\u00e1u \u0111\u00f4ng n\u00e0y b\u1ecb r\u1eddi ra, di chuy\u1ec3n qua d\u00f2ng m\u00e1u v\u00e0 ch\u1eb7n l\u1ea1i trong ph\u1ed5i [1].<\/p>\n
VTE x\u1ea3y ra \u1edf c\u1ea3 nam v\u00e0 n\u1eef, v\u00e0 c\u00f3 th\u1ec3 x\u1ea3y ra trong su\u1ed1t cu\u1ed9c \u0111\u1eddi c\u1ee7a h\u1ecd [2]. Tuy nhi\u00ean, nguy c\u01a1 VTE su\u1ed1t \u0111\u1eddi \u01b0\u1edbc t\u00ednh x\u1ea3y ra \u1edf ph\u1ee5 n\u1eef, \u0111\u1eb7c bi\u1ec7t trong nh\u1eefng n\u0103m sinh \u0111\u1ebb, cao h\u01a1n so v\u1edbi nam gi\u1edbi [2].<\/p>\n
T\u1ef7 l\u1ec7 m\u1eafc VTE to\u00e0n c\u1ea7u trong d\u00e2n s\u1ed1 chung \u01b0\u1edbc t\u00ednh l\u00e0 1\u20142 ca m\u1ed7i 1.000 ng\u01b0\u1eddi m\u1ed7i n\u0103m, t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi 3 ho\u1eb7c 10 tri\u1ec7u ca VTE m\u1ed7i n\u0103m [4].\u00a0Tuy nhi\u00ean, v\u1eabn c\u00f2n r\u1ea5t \u00edt d\u1eef li\u1ec7u \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh ch\u00ednh x\u00e1c t\u1ef7 l\u1ec7 m\u1eafc VTE, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf ph\u1ee5 n\u1eef.<\/p>\n
Cho \u0111\u1ebfn g\u1ea7n \u0111\u00e2y, s\u1ef1 xu\u1ea5t hi\u1ec7n c\u1ee7a VTE trong d\u00e2n s\u1ed1 Ch\u00e2u \u00c1 \u0111\u01b0\u1ee3c cho l\u00e0 th\u1ea5p h\u01a1n so v\u1edbi ng\u01b0\u1eddi da tr\u1eafng. Tuy nhi\u00ean, c\u00e1c nghi\u00ean c\u1ee9u cho th\u1ea5y r\u1eb1ng \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 do vi\u1ec7c \u0111\u00e1nh gi\u00e1 th\u1ea5p t\u1ef7 l\u1ec7 VTE \u1edf Ch\u00e2u \u00c1, do vi\u1ec7c ch\u1ea9n \u0111o\u00e1n thi\u1ebfu s\u00f3t v\u00e0 b\u00e1o c\u00e1o kh\u00f4ng \u0111\u1ea7y \u0111\u1ee7 [5,6]. V\u1edbi nh\u1eadn th\u1ee9c n\u00e2ng cao h\u01a1n r\u1eb1ng VTE l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 trong d\u00e2n s\u1ed1 Ch\u00e2u \u00c1 v\u00e0 ch\u1ea9n \u0111o\u00e1n \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n, s\u1ed1 l\u01b0\u1ee3ng ca VTE \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o c\u00f3 v\u1ebb nh\u01b0 \u0111ang t\u0103ng l\u00ean [5].<\/p>\n
C\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 g\u00e2y VTE \u1edf ph\u1ee5 n\u1eef t\u01b0\u01a1ng t\u1ef1 nh\u01b0 \u1edf d\u00e2n s\u1ed1 chung, ngo\u1ea1i tr\u1eeb vi\u1ec7c ch\u00fang gia t\u0103ng trong nh\u1eefng n\u0103m sinh \u1ebbe [1,2].<\/p>\n
\u00a0 <\/p>\n
C\u00e1c li\u1ec7u ph\u00e1p n\u1ed9i ti\u1ebft t\u1ed1 \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n cho ph\u1ee5 n\u1eef\u2014\u0111\u1eb7c bi\u1ec7t l\u00e0 thu\u1ed1c tr\u00e1nh thai k\u1ebft h\u1ee3p (COC) v\u00e0 li\u1ec7u ph\u00e1p thay th\u1ebf n\u1ed9i ti\u1ebft t\u1ed1 (HRT)\u2014\u0111\u00e3 ch\u1ee9ng minh t\u00e1c d\u1ee5ng l\u00ean qu\u00e1 tr\u00ecnh \u0111\u00f4ng m\u00e1u v\u00e0 l\u00e0m t\u0103ng nguy c\u01a1 VTE g\u1ea5p 2\u20144 l\u1ea7n so v\u1edbi nh\u1eefng ng\u01b0\u1eddi kh\u00f4ng m\u1eafc VTE. C\u00e1c li\u1ec7u ph\u00e1p n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 g\u00e2y ra s\u1ef1 kh\u00e1ng thu\u1ed1c c\u00f3 \u0111\u01b0\u1ee3c \u0111\u1ed1i v\u1edbi protein C ho\u1ea1t h\u00f3a, m\u1ed9t y\u1ebfu t\u1ed1 c\u1ea7n thi\u1ebft \u0111\u1ec3 s\u1ea3n xu\u1ea5t m\u1ed9t ch\u1ea5t ch\u1ed1ng \u0111\u00f4ng t\u1ef1 nhi\u00ean, protein S. Ngo\u00e0i ra, c\u00e1c li\u1ec7u ph\u00e1p n\u1ed9i ti\u1ebft t\u1ed1 k\u1ebft h\u1ee3p trong COC v\u00e0 HRT l\u00e0m t\u0103ng m\u1ed9t s\u1ed1 y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u (prothrombin, c\u00e1c y\u1ebfu t\u1ed1 VII, VIII v\u00e0 X) v\u00e0 gi\u1ea3m c\u00e1c ch\u1ea5t ch\u1ed1ng \u0111\u00f4ng t\u1ef1 nhi\u00ean kh\u00e1c (antithrombin) [8,9].<\/p>\n
C\u00e1c li\u1ec7u ph\u00e1p n\u1ed9i ti\u1ebft t\u1ed1 c\u0169ng \u0111\u00e3 li\u00ean k\u1ebft v\u1edbi vi\u1ec7c l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a thrombophilia di truy\u1ec1n (m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n l\u00e0m t\u0103ng \u0111\u1ed9 \u0111\u00f4ng m\u00e1u c\u1ee7a m\u00e1u) [9,11].\u00a0C\u00e1c lo\u1ea1i thrombophilia di truy\u1ec1n ph\u1ed5 bi\u1ebfn bao g\u1ed3m y\u1ebfu t\u1ed1 V Leiden, thi\u1ebfu h\u1ee5t protein C, thi\u1ebfu h\u1ee5t protein S v\u00e0 thi\u1ebfu h\u1ee5t antithrombin [11].<\/p>\n
Nguy c\u01a1 ph\u00e1t tri\u1ec3n VTE \u1edf ph\u1ee5 n\u1eef \u0111ang s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p n\u1ed9i ti\u1ebft t\u1ed1 ho\u1eb7c mang thai \u0111\u01b0\u1ee3c tr\u00ecnh b\u00e0y trong c\u00e1c b\u1ea3ng d\u01b0\u1edbi \u0111\u00e2y. V\u00ec thrombophilia di truy\u1ec1n l\u00e0\u00a0r\u1ea5t hi\u1ebfm, vi\u1ec7c s\u00e0ng l\u1ecdc c\u00e1c t\u00ecnh tr\u1ea1ng n\u00e0y kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb. Tuy nhi\u00ean, vi\u1ec7c x\u00e9t nghi\u1ec7m \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb cho nh\u1eefng ph\u1ee5 n\u1eef l\u00e0 ng\u01b0\u1eddi th\u00e2n kh\u00f4ng c\u00f3 tri\u1ec7u ch\u1ee9ng c\u1ee7a nh\u1eefng ng\u01b0\u1eddi mang gen thrombophilia n\u1eb7ng (y\u1ebfu t\u1ed1 V Leiden) [12].<\/p>\n
\u00a0 <\/p>\n
\n
70\u201480% c\u00e1c ca VTE trong thai k\u1ef3 l\u00e0 huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT) \u1edf chi d\u01b0\u1edbi, v\u00e0 43\u201460% c\u00e1c ca thuy\u00ean t\u1eafc ph\u1ed5i (PE) x\u1ea3y ra trong 6 tu\u1ea7n \u0111\u1ea7u sau sinh [8].<\/p>\n
\u00a0 <\/p>\n
C\u00e1c y\u1ebfu t\u1ed1 kh\u00e1c l\u00e0m t\u0103ng nguy c\u01a1 VTE \u1edf ph\u1ee5 n\u1eef c\u00f3 th\u1ec3 bao g\u1ed3m thi\u1ebfu v\u1eadn \u0111\u1ed9ng trong qu\u00e1 tr\u00ecnh h\u1ed3i ph\u1ee5c sau c\u00e1c ca ph\u1eabu thu\u1eadt l\u1edbn; gi\u00e3n t\u0129nh m\u1ea1ch ch\u01b0a \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb; ung th\u01b0 v\u00e0 \u0111i\u1ec1u tr\u1ecb ung th\u01b0; c\u00e1c b\u1ec7nh tim m\u1ea1ch v\u00e0 \u0111\u1ed9t qu\u1ef5; ti\u1ec1n s\u1eed gia \u0111\u00ecnh c\u00f3 VTE; b\u00e9o ph\u00ec; h\u00fat thu\u1ed1c; v\u00e0 u\u1ed1ng r\u01b0\u1ee3u.<\/p>\n
Vi\u1ec7c s\u1eb5n c\u00f3 c\u00e1c bi\u1ec7n ph\u00e1p COC c\u00f3 nguy c\u01a1 th\u1ea5p h\u01a1n v\u00e0 s\u1ef1 gi\u1ea3m b\u1edbt vi\u1ec7c k\u00ea \u0111\u01a1n li\u1ec7u ph\u00e1p thay th\u1ebf n\u1ed9i ti\u1ebft t\u1ed1 (HRT) \u0111\u00e3 g\u00f3p ph\u1ea7n gi\u1ea3m nguy c\u01a1 VTE \u1edf ph\u1ee5 n\u1eef c\u00f3 nguy c\u01a1. Tuy nhi\u00ean, s\u1ef1 t\u01b0\u01a1ng t\u00e1c ph\u1ee9c t\u1ea1p ti\u1ec1m \u1ea9n c\u1ee7a c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 kh\u00e1c v\u00e0 nh\u1eefng r\u1ee7i ro v\u1ed1n c\u00f3 c\u1ee7a thai k\u1ef3 \u0111\u00f2i h\u1ecfi ph\u1ea3i ph\u00e1t tri\u1ec3n c\u00e1c h\u01b0\u1edbng d\u1eabn to\u00e0n di\u1ec7n v\u00e0 ph\u00f9 h\u1ee3p v\u1edbi \u0111\u1eb7c th\u00f9 c\u1ee7a khu v\u1ef1c Ch\u00e2u \u00c1 – Th\u00e1i B\u00ecnh D\u01b0\u01a1ng.<\/p>\n
V\u00ed d\u1ee5, c\u00e1c h\u01b0\u1edbng d\u1eabn c\u1ee7a Singapore \u0111\u00e3 ch\u1ec9nh s\u1eeda c\u00e1c h\u01b0\u1edbng d\u1eabn c\u1ee7a Royal College of Obstetricians and Gynaecologists \u0111\u1ec3 ph\u1ea3n \u00e1nh t\u1ef7 l\u1ec7 thrombophilia m\u1ea1nh h\u01a1n trong qu\u1ea7n th\u1ec3 ng\u01b0\u1eddi ch\u00e2u \u00c1, \u0111\u01b0a \u0111\u1ed9 tu\u1ed5i >35 tu\u1ed5i v\u00e0o y\u1ebfu t\u1ed1 nguy c\u01a1 \u0111\u1ed1i v\u1edbi VTE sau sinh, bao g\u1ed3m h\u01b0\u1edbng d\u1eabn v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c g\u00e2y t\u00ea ngo\u00e0i m\u00e0ng c\u1ee9ng cho b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 VTE, v\u00e0 \u0111i\u1ec1u ch\u1ec9nh c\u00e1c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb sao cho ph\u00f9 h\u1ee3p v\u1edbi \u0111\u1eb7c th\u00f9 c\u1ee7a d\u00e2n s\u1ed1 \u0111\u1ecba ph\u01b0\u01a1ng.<\/p>\n
VTE (DVT<\/a>) \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n ch\u1ee7 y\u1ebfu b\u1eb1ng b\u1ec7nh s\u1eed v\u00e0 kh\u00e1m l\u00e2m s\u00e0ng, m\u1eb7c d\u00f9 c\u00e1c x\u00e9t nghi\u1ec7m c\u0169ng c\u00f3 vai tr\u00f2. C\u00e1c ph\u01b0\u01a1ng th\u1ee9c ch\u1ea9n \u0111o\u00e1n ch\u00ednh nh\u01b0 sau:<\/p>\n C\u00f3 nhi\u1ec1u c\u00f4ng c\u1ee5 kh\u00e1c nhau d\u01b0\u1edbi d\u1ea1ng c\u00e2u h\u1ecfi \u0111i\u1ec1u tra \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 nguy c\u01a1 g\u00e2y VTE \u1edf ph\u1ee5 n\u1eef. M\u1ed9t s\u1ed1 c\u00e2u h\u1ecfi trong c\u00e1c c\u00f4ng c\u1ee5 \u0111\u00e1nh gi\u00e1 n\u00e0y bao g\u1ed3m c\u00e1c c\u00e2u h\u1ecfi v\u1ec1:<\/p>\n \u00a0 <\/p>\n Ph\u00f2ng ng\u1eeba VTE (huy\u1ebft kh\u1ed1i d\u1ef1 ph\u00f2ng) cho ph\u1ee5 n\u1eef kh\u00f4ng mang thai t\u01b0\u01a1ng t\u1ef1 nh\u01b0 \u0111i\u1ec1u tr\u1ecb cho nam gi\u1edbi. D\u1ef1 ph\u00f2ng cho nh\u1eefng ng\u01b0\u1eddi tr\u1ea3i qua ph\u1eabu thu\u1eadt c\u00f3 nguy c\u01a1 cao, t\u00f9y thu\u1ed9c v\u00e0o nguy c\u01a1 ch\u1ea3y m\u00e1u [6].<\/p>\n \u0110\u1ed1i v\u1edbi ph\u1ee5 n\u1eef mang thai, thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn \u0111\u1ec3 d\u1ef1 ph\u00f2ng l\u00e0 LMWH. Th\u1eddi \u0111i\u1ec3m \u0111i\u1ec1u tr\u1ecb d\u1ef1 ph\u00f2ng s\u1ebd ph\u1ee5 thu\u1ed9c v\u00e0o \u0111i\u1ec3m \u0111\u00e1nh gi\u00e1 nguy c\u01a1. Nh\u1eefng ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 cao h\u01a1n s\u1ebd \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb d\u1ef1 ph\u00f2ng khi c\u00f3 x\u00e1c nh\u1eadn mang thai, trong khi nh\u1eefng ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 th\u1ea5p h\u01a1n \u0111\u01b0\u1ee3c b\u1eaft \u0111\u1ea7u t\u1eeb tu\u1ea7n mang thai th\u1ee9 28 (ba th\u00e1ng cu\u1ed1i thai k\u1ef3) [13]. Ph\u1ee5 n\u1eef c\u1ea7n \u0111\u01b0\u1ee3c d\u1ef1 ph\u00f2ng trong thai k\u1ef3 c\u0169ng s\u1ebd c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb d\u1ef1 ph\u00f2ng trong \u00edt nh\u1ea5t 6 tu\u1ea7n sau khi sinh.<\/p>\n \u0110i\u1ec1u tr\u1ecb VTE \u1edf ph\u1ee5 n\u1eef, ngo\u1ea1i tr\u1eeb trong thai k\u1ef3, t\u01b0\u01a1ng t\u1ef1 nh\u01b0 \u0111i\u1ec1u tr\u1ecb cho nam gi\u1edbi. Bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb ch\u00ednh l\u00e0 s\u1eed d\u1ee5ng c\u00e1c ch\u1ea5t ch\u1ed1ng \u0111\u00f4ng m\u00e1u nh\u01b0 heparin, heparin tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed th\u1ea5p (LMWH), ch\u1ea5t \u0111\u1ed1i kh\u00e1ng vitamin K v\u00e0 c\u00e1c ch\u1ea5t ch\u1ed1ng \u0111\u00f4ng tr\u1ef1c ti\u1ebfp \u0111\u01b0\u1eddng u\u1ed1ng (DOAC). Trong s\u1ed1 n\u00e0y, LMWH v\u00e0 DOAC c\u00f3 nguy c\u01a1 ch\u1ea3y m\u00e1u th\u1ea5p h\u01a1n.<\/p>\n \u0110\u1ed1i v\u1edbi VTE trong khi mang thai, LMWH l\u00e0 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn. Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u \u0111\u01b0\u1ee3c d\u00f9ng li\u1ec1u \u0111i\u1ec1u tr\u1ecb trong su\u1ed1t th\u1eddi gian mang thai v\u00e0 l\u00ean \u0111\u1ebfn 6 tu\u1ea7n sau sinh, trong t\u1ed1i thi\u1ec3u 3 th\u00e1ng. Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, vi\u1ec7c \u0111\u00e1nh gi\u00e1 l\u1ea1i \u0111i\u1ec3m nguy c\u01a1 VTE n\u00ean \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u01b0\u1edbc khi gi\u1ea3m li\u1ec1u ho\u1eb7c ng\u1eebng \u0111i\u1ec1u tr\u1ecb [13].<\/p>\n T\u00e0i li\u1ec7u tham kh\u1ea3o:\u00a0<\/em><\/p>\n [1]<\/a> National Heart, Lung, and Blood Institute. What is venous thromboembolism. Truy c\u1eadp: https:\/\/www.nhlbi.nih.gov\/health\/venous-thromboembolism. Accessed October 2022. [2]<\/a> Arnesen CAL, Veres K, Horv\u00e1th-Puh\u00f3 E, Hansen JB, S\u00f8rensen HT, Br\u00e6kkan SK. Estimated lifetime risk of venous thromboembolism in men and women in a Danish nationwide cohort: impact of competing risk of death. Eur J Epidemiol. Feb 2022;37(2):195-203. doi:10.1007\/s10654-021-00813-w. [3] <\/a>Scheres LJJ, Lijfering WM, Cannegieter SC. Current and future burden of venous thrombosis: Not simply predictable. Res Pract Thromb Haemost. Apr 2018;2(2):199-208. doi:10.1002\/rth2.12101. [4]<\/a> World Thrombosis Day. Open your eyes to venous thromboembolism (VTE). Truy c\u1eadp: https:\/\/www.worldthrombosisday.org\/issue\/vte\/#:~:text=Every%20year%2C%20there %20are%20approximately%2010%20million%20cases%20of%20VTE%20worldwide. Accessed October 2022. [5]<\/a> Lee LH, Gallus A, Jindal R, Wang C, Wu CC. Incidence of Venous Thromboembolism in Asian Populations: A Systematic Review. Thromb Haemost. Dec 2017;117(12):2243-2260. doi:10.1160\/th17-02-0134. [6]<\/a> Wang KL, Yap ES, Goto S, Zhang S, Siu CW, Chiang CE. The diagnosis and treatment of venous thromboembolism in asian patients. Thromb J. 2018;16:4. doi:10.1186\/s12959-017-0155-z. [7]<\/a> National Blood Clot Alliance. Women and blood clots risk timeline. Truy c\u1eadp: https:\/\/www.stoptheclot.org\/news\/may-is-womens-health-month\/. Accessed October 2022. [8]<\/a> de Oliveira A, Pasch\u00f4a AF, Marques MA. Venous thromboembolism in women: new challenges for an old disease. J Vasc Bras. Jul 6 2020;19:e20190148. doi:10.1590\/1677-5449.190148. [9]<\/a> Jacobsen AF, Sandset PM. Venous thromboembolism associated with pregnancy and hormonal therapy. Best Pract Res Clin Haematol. Sep 2012;25(3):319-32. doi:10.1016\/j.beha.2012.07.006. [10]<\/a> Sennstr\u00f6m M, Rova K, Hellgren M, et al. Thromboembolism and in vitro fertilization – a systematic review. Acta Obstet Gynecol Scand. Sep 2017;96(9):1045-1052. doi:10.1111\/aogs.13147. [11]<\/a> National Health Services (United Kingdom). Thrombophilia. Truy c\u1eadp: https:\/\/www.nhs.uk\/conditions\/thrombophilia\/. Accessed October 2022. [12]<\/a> Gialeraki A, Valsami S, Pittaras T, Panayiotakopoulos G, Politou M. Oral Contraceptives and HRT Risk of Thrombosis. Clin Appl Thromb Hemost. Mar 2018;24(2):217-225. doi:10.1177\/1076029616683802. [13]<\/a> Academy of Medicine Singapore, College of Obstetricians & Gynaecologists Singapore, Chapter of Haematologists College of Physicians Singapore. Venous thrombolism in pregnancy – Recommendation for prevention, treatment and investigation. March 2021. Truy c\u1eadp: https:\/\/www.ams.edu.sg\/view-pdf.aspx?file=media%5C6016_fi_257.pdf&ofile=CPS-COGS+VTE+Consensus+Statement+2021+0326.pdf. Accessed October 2022.<\/p>\n","protected":false},"excerpt":{"rendered":" Thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch (VTE) ch\u1ec9 c\u00e1c c\u1ee5c m\u00e1u \u0111\u00f4ng ph\u00e1t tri\u1ec3n trong t\u0129nh m\u1ea1ch [1]. Hai bi\u1ec3u hi\u1ec7n ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a VTE l\u00e0 huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT) v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i (PE) [1]. DVT x\u1ea3y ra khi m\u1ed9t c\u1ee5c m\u00e1u \u0111\u00f4ng ph\u00e1t tri\u1ec3n trong m\u1ed9t t\u0129nh m\u1ea1ch s\u00e2u, v\u00e0 […]<\/p>\n","protected":false},"author":1,"featured_media":85676,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"tags":[14793,14795],"pillarandcategory":[288,292,282],"reporter":[14949,14950],"class_list":["post-147182","acf_article","type-acf_article","status-publish","has-post-thumbnail","hentry","tag-dong-mau","tag-suc-khoe-phu-nu","pillarandcategory-womens-health","pillarandcategory-coagulation","pillarandcategory-disease-area","reporter-niti-dawar","reporter-yingli-huang"],"acf":[],"_links":{"self":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article"}],"about":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/types\/acf_article"}],"author":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":1,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147182\/revisions"}],"predecessor-version":[{"id":147503,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147182\/revisions\/147503"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media\/85676"}],"wp:attachment":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media?parent=147182"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/tags?post=147182"},{"taxonomy":"pillarandcategory","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/pillarandcategory?post=147182"},{"taxonomy":"reporter","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/reporter?post=147182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\n
C\u00f4ng c\u1ee5 \u0111\u00e1nh gi\u00e1 nguy c\u01a1 VTE cho ph\u1ee5 n\u1eef<\/h2>\n
Ph\u00f2ng ng\u1eeba VTE \u1edf ph\u1ee5 n\u1eef<\/h2>\n
\u0110i\u1ec1u tr\u1ecb VTE \u1edf ph\u1ee5 n\u1eef<\/h2>\n