{"id":147306,"date":"2020-08-25T00:42:35","date_gmt":"2020-08-25T00:42:35","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/xet-nghiem-tai-cho-de-kiem-soat-dai-dich-phong-van-tien-si-gerald-kost\/"},"modified":"2026-02-23T07:01:23","modified_gmt":"2026-02-23T07:01:23","slug":"point-of-care-testing-for-pandemic-management-an-interview-with-dr-gerald-kost","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/vi\/operations\/point-of-care\/point-of-care-testing-for-pandemic-management-an-interview-with-dr-gerald-kost\/","title":{"rendered":"X\u00e9t nghi\u1ec7m t\u1ea1i ch\u1ed7 \u0111\u1ec3 ki\u1ec3m so\u00e1t \u0111\u1ea1i d\u1ecbch: ph\u1ecfng v\u1ea5n Ti\u1ebfn s\u0129 Gerald Kost"},"content":{"rendered":"<p><em>V\u1edbi t\u01b0 c\u00e1ch l\u00e0 Gi\u00e1m \u0111\u1ed1c Point-of-Care Testing Center for Teaching and Research (POCT\u2022CTR) v\u00e0 Gi\u00e1o s\u01b0 Danh d\u1ef1 v\u1ec1 B\u1ec7nh h\u1ecdc v\u00e0 Y h\u1ecdc Ph\u00f2ng x\u00e9t nghi\u1ec7m t\u1ea1i University of California Davis School of Medicine, Ti\u1ebfn s\u0129 Gerald Kost l\u00e0 m\u1ed9t trong nh\u1eefng chuy\u00ean gia h\u00e0ng \u0111\u1ea7u th\u1ebf gi\u1edbi v\u1ec1 x\u00e9t nghi\u1ec7m t\u1ea1i ch\u1ed7 (POCT). \u00d4ng c\u0169ng l\u00e0 H\u1ecdc gi\u1ea3 Fulbright 2020-2021 t\u1ea1i ASEAN. Trong ph\u1ea7n h\u1ecfi \u0111\u00e1p n\u00e0y, \u00f4ng chia s\u1ebb nh\u1eefng th\u00f4ng tin chuy\u00ean s\u00e2u \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 POCT m\u1edbi nh\u1eb1m ki\u1ec3m so\u00e1t COVID-19, tri\u1ec3n khai c\u00e1c x\u00e9t nghi\u1ec7m n\u00e0y trong th\u1ef1c h\u00e0nh l\u00e2m s\u00e0ng v\u00e0 ph\u00e1t tri\u1ec3n c\u00e1c ch\u00ednh s\u00e1ch nh\u1eb1m th\u00fac \u0111\u1ea9y \u0111\u1ed5i m\u1edbi trong ch\u1ea9n \u0111o\u00e1n v\u00e0 gi\u00fap ng\u0103n ch\u1eb7n s\u1ef1 b\u00f9ng ph\u00e1t c\u1ee7a c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m cao trong t\u01b0\u01a1ng lai.<\/em><\/p>\n<h2 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 28px !important; line-height: 36px !important; letter-spacing: 0px !important;\">M\u1ed9t s\u1ed1 c\u00e2n nh\u1eafc ch\u00ednh \u0111\u1ec3 tri\u1ec3n khai POCT c\u00f3 hi\u1ec7u qu\u1ea3 trong \u0111\u1ea1i d\u1ecbch hi\u1ec7n nay l\u00e0 g\u00ec?<\/h3>\n<p>M\u1ed9t c\u00e2n nh\u1eafc quan tr\u1ecdng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 x\u00e9t nghi\u1ec7m COVID-19 m\u1edbi l\u00e0 lo\u1ea1i b\u1ecf k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m \u00e2m t\u00ednh gi\u1ea3. \u0110\u1ec3 l\u00e0m \u0111\u01b0\u1ee3c \u0111i\u1ec1u \u0111\u00f3, x\u00e9t nghi\u1ec7m c\u1ea7n ph\u1ea3i c\u00f3 \u0111\u1ed9 nh\u1ea1y cao, \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh b\u1eb1ng t\u1ef7 l\u1ec7 k\u1ebft qu\u1ea3 d\u01b0\u01a1ng t\u00ednh th\u1ef1c (true positive, TP) so v\u1edbi t\u1ed5ng k\u1ebft qu\u1ea3 d\u01b0\u01a1ng t\u00ednh th\u1ef1c v\u00e0 \u00e2m t\u00ednh gi\u1ea3 (false negative, FN) [TP\/(TP + FN)], cho d\u00f9 x\u00e9t nghi\u1ec7m \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1ea1i ch\u1ed7 hay \u1edf n\u01a1i kh\u00e1c. C\u00e1c m\u00f4 h\u00ecnh to\u00e1n h\u1ecdc v\u1ec1 hi\u1ec7u su\u1ea5t x\u00e9t nghi\u1ec7m l\u00e0 c\u1ef1c k\u1ef3 quan tr\u1ecdng \u0111\u1ec3 thi\u1ebft l\u1eadp chi\u1ebfn l\u01b0\u1ee3c x\u00e9t nghi\u1ec7m. Bi\u1ec3u \u0111\u1ed3 d\u01b0\u1edbi \u0111\u00e2y xem x\u00e9t ba \u201cb\u1eadc\u201d kh\u00e1c nhau c\u1ee7a ch\u1ea5t l\u01b0\u1ee3ng x\u00e9t nghi\u1ec7m, cho th\u1ea5y t\u1ef7 l\u1ec7 d\u01b0\u01a1ng t\u00ednh gi\u1ea3 so v\u1edbi d\u01b0\u01a1ng t\u00ednh th\u1ef1c (FP\/TP), gi\u00e1 tr\u1ecb ti\u00ean \u0111o\u00e1n d\u01b0\u01a1ng t\u00ednh (positive predictive value, PPV), gi\u00e1 tr\u1ecb ti\u00ean \u0111o\u00e1n \u00e2m t\u00ednh (negative predictive value, NPV), v\u00e0 t\u1ef7 l\u1ec7 b\u1ecf s\u00f3t gi\u1ea3 (false omission rate, RFO) \u0111\u01b0\u1ee3c quy\u1ebft \u0111\u1ecbnh b\u1edfi t\u1ef7 l\u1ec7 hi\u1ec7n h\u00e0nh (t\u1eeb tham chi\u1ebfu 1). <img fetchpriority=\"high\" decoding=\"async\" class=\" size-full wp-image-84731\" src=\"\/wp-content\/uploads\/2020\/08\/Kost-image1-685-scaled.jpg\" alt=\"Kostimage1\" width=\"2560\" height=\"1920\" data-entity-type=\"file\" data-entity-uuid=\"8982e9c5-3ba0-46af-b9f1-1e3c6de6ca4d\" title=\"\" srcset=\"https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image1-685-scaled.jpg 2560w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image1-685-268x201.jpg 268w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image1-685-1024x768.jpg 1024w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image1-685-768x576.jpg 768w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image1-685-1536x1152.jpg 1536w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image1-685-2048x1536.jpg 2048w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/> V\u1edbi t\u1ef7 l\u1ec7 hi\u1ec7n h\u00e0nh th\u1ea5p l\u00e0 2-5%, c\u1ea7n x\u00e9t nghi\u1ec7m B\u1eadc 3 v\u1edbi \u0111\u1ed9 nh\u1ea1y (100%) v\u00e0 \u0111\u1ed9 \u0111\u1eb7c hi\u1ec7u r\u1ea5t cao (\u2265 99%). H\u1ea7u h\u1ebft c\u00e1c c\u1ed9ng \u0111\u1ed3ng \u0111ang ghi nh\u1eadn t\u1ef7 l\u1ec7 hi\u1ec7n h\u00e0nh th\u1ea5p. Trong ph\u00f2ng c\u1ea5p c\u1ee9u (ER), c\u00e1c b\u00e1c s\u0129 l\u00e2m s\u00e0ng ghi nh\u1eadn nhi\u1ec1u b\u1ec7nh nh\u00e2n nhi\u1ec5m b\u1ec7nh h\u01a1n, do \u0111\u00f3 x\u00e1c su\u1ea5t m\u1eafc COVID-19 tr\u01b0\u1edbc x\u00e9t nghi\u1ec7m t\u0103ng l\u00ean, v\u00e0 k\u1ebft qu\u1ea3 l\u00e0 t\u1ef7 l\u1ec7 hi\u1ec7n h\u00e0nh th\u1ef1c s\u1ef1 c\u0169ng t\u0103ng l\u00ean. Do \u0111\u00f3, t\u1ef7 l\u1ec7 hi\u1ec7n h\u00e0nh ph\u1ee5 thu\u1ed9c v\u00e0o b\u1ed1i c\u1ea3nh.<\/p>\n<h3 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 24px !important; line-height: 32px !important; letter-spacing: 0px !important;\">M\u1ed9t s\u1ed1 x\u00e9t nghi\u1ec7m \u0111\u1ea7y h\u1ee9a h\u1eb9n m\u00e0 c\u00e1c nh\u00e0 ch\u1ee9c tr\u00e1ch c\u00f3 th\u1ec3 xem x\u00e9t cho POCT COVID-19 l\u00e0 g\u00ec?<\/h3>\n<p>B\u1ea5t k\u1ef3 x\u00e9t nghi\u1ec7m n\u00e0o c\u00f3 x\u00e1c nh\u1eadn hi\u1ec7u su\u1ea5t cao kh\u00e1ch quan trong B\u1eadc 3 \u0111\u1ec1u r\u1ea5t h\u1ee9a h\u1eb9n \u0111\u1ec3 tri\u1ec3n khai \u0111\u1ea7y \u0111\u1ee7 nh\u1eb1m ki\u1ec3m so\u00e1t \u0111\u1ea1i d\u1ecbch hi\u1ec7n t\u1ea1i c\u0169ng nh\u01b0 c\u00e1c \u0111\u1ee3t b\u00f9ng ph\u00e1t m\u1edbi. \u0110i\u1ec1u n\u00e0y bao g\u1ed3m c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n ph\u00e2n t\u1eed \u0111\u1ec3 ph\u00e1t hi\u1ec7n ban \u0111\u1ea7u \u0111\u1ed1i v\u1edbi SARS-CoV-2 ho\u1eb7c c\u00e1c x\u00e9t nghi\u1ec7m kh\u00e1ng th\u1ec3 \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch sau khi nhi\u1ec5m b\u1ec7nh ho\u1eb7c ch\u1ee7ng ng\u1eeba. C\u00f3 th\u1ec3 xem c\u00e1c x\u00e9t nghi\u1ec7m \u0111\u01b0\u1ee3c Food and Drug Administration t\u1ea1i Hoa K\u1ef3 ph\u00ea duy\u1ec7t theo Gi\u1ea5y ph\u00e9p s\u1eed d\u1ee5ng kh\u1ea9n c\u1ea5p trong t\u00e0i li\u1ec7u tham kh\u1ea3o 10. C\u00f3 m\u1ed9t c\u1ea3nh b\u00e1o l\u00e0 nhi\u1ec1u x\u00e9t nghi\u1ec7m tr\u00ean th\u1ecb tr\u01b0\u1eddng kh\u00f4ng c\u00f3 hi\u1ec7u su\u1ea5t t\u1ed1t. POCT kh\u00f4ng n\u00ean l\u00e0 l\u00fd do cho k\u1ebft qu\u1ea3 kh\u00f4ng ch\u00ednh x\u00e1c. Chuy\u00ean gia y t\u1ebf n\u00ean \u0111\u00e1nh gi\u00e1 hi\u1ec7u su\u1ea5t c\u1ee7a POCT tr\u01b0\u1edbc khi tri\u1ec3n khai x\u00e9t nghi\u1ec7m \u0111\u00f3 cho COVID-19.<\/p>\n<h3 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 24px !important; line-height: 32px !important; letter-spacing: 0px !important;\">C\u00e1c chuy\u00ean gia ph\u00f2ng x\u00e9t nghi\u1ec7m l\u00e2m s\u00e0ng c\u00f3 th\u1ec3 \u0111\u00f3ng g\u00f3p v\u00e0o vi\u1ec7c tri\u1ec3n khai POC \u0111\u1ec3 ki\u1ec3m so\u00e1t COVID-19 nh\u01b0 th\u1ebf n\u00e0o?<\/h3>\n<p>H\u00e0ng ch\u1ee5c khuy\u1ebfn ngh\u1ecb \u0111\u01b0\u1ee3c li\u1ec7t k\u00ea d\u01b0\u1edbi \u0111\u00e2y cho th\u1ea5y c\u00e1ch c\u00e1c chuy\u00ean gia ph\u00f2ng th\u00ed nghi\u1ec7m c\u00f3 th\u1ec3 tri\u1ec3n khai POCT \u0111\u1ec3 ki\u1ec3m so\u00e1t \u0111\u1ea1i d\u1ecbch, gi\u00fap \u0111\u1ee1 c\u00e1c b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m b\u1ec7nh c\u1ea5p t\u00ednh v\u00e0 \u0111\u1ea9y nhanh qu\u00e1 tr\u00ecnh ra quy\u1ebft \u0111\u1ecbnh, \u0111i\u1ec1u tr\u1ecb v\u00e0 ph\u1ee5c h\u1ed3i.<\/p>\n<ul>\n<li>Thu th\u1eadp m\u1eabu b\u1ec7nh ph\u1ea9m, s\u00e0ng l\u1ecdc v\u00e0 \u0111\u00e1nh gi\u00e1 m\u1ecdi ng\u01b0\u1eddi m\u1ed9t c\u00e1ch an to\u00e0n b\u1eb1ng c\u00e1ch l\u00e1i xe \u0111\u1ebfn \u0111\u1ecba \u0111i\u1ec3m x\u00e9t nghi\u1ec7m\/l\u00e1i xe v\u00e0o \u0111\u1ecba \u0111i\u1ec3m x\u00e9t nghi\u1ec7m\/x\u00e9t nghi\u1ec7m t\u1ea1i xe, \u0111i b\u1ed9 \u0111\u1ebfn \u0111\u1ecba \u0111i\u1ec3m x\u00e9t nghi\u1ec7m v\u00e0 c\u01a1 s\u1edf x\u00e9t nghi\u1ec7m l\u01b0u \u0111\u1ed9ng \u0111\u1ec3 ng\u0103n ng\u1eeba s\u1ef1 l\u00e2y lan<\/li>\n<li>\u0110\u1ea3m b\u1ea3o hi\u1ec7u su\u1ea5t x\u00e9t nghi\u1ec7m cao v\u1edbi gi\u00e1 tr\u1ecb ti\u00ean \u0111o\u00e1n d\u01b0\u01a1ng t\u00ednh [TP\/(TP + FP)] v\u00e0 gi\u00e1 tr\u1ecb ti\u00ean \u0111o\u00e1n \u00e2m t\u00ednh [TN\/(TN + FN)] tuy\u1ec7t v\u1eddi<\/li>\n<li>Gi\u1ea3i t\u1ecfa c\u01a1 s\u1edf h\u1ea1 t\u1ea7ng b\u1ec7nh vi\u1ec7n b\u1eb1ng c\u00e1ch h\u1ea1n ch\u1ebf g\u00e1nh n\u1eb7ng trong ph\u00f2ng c\u1ea5p c\u1ee9u, nh\u1eadp vi\u1ec7n kh\u00f4ng c\u1ea7n thi\u1ebft v\u00e0 t\u00e1i nh\u1eadp vi\u1ec7n \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 th\u1ea5p<\/li>\n<li>Ph\u00e2n bi\u1ec7t b\u1ec7nh c\u00fam A\/B th\u00f4ng th\u01b0\u1eddng v\u1edbi COVID-19<\/li>\n<li>Ph\u00e1t hi\u1ec7n s\u1ef1 l\u00e2y truy\u1ec1n COVID-19 \u00e2m th\u1ea7m th\u00f4ng qua vi\u1ec7c ti\u1ebfp c\u1eadn r\u1ed9ng r\u00e3i v\u1edbi ho\u1ea1t \u0111\u1ed9ng x\u00e9t nghi\u1ec7m v\u00e0 t\u1ef1 x\u00e9t nghi\u1ec7m<\/li>\n<li>\u0110\u1ea9y nhanh ch\u1ea9n \u0111o\u00e1n ph\u00e2n t\u1eed, ph\u00e2n lo\u1ea1i, c\u00e1ch ly v\u00e0 ra quy\u1ebft \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m SARS-CoV-2<\/li>\n<li>H\u1ed7 tr\u1ee3 y t\u1ebf c\u00f4ng c\u1ed9ng truy v\u1ebft ng\u01b0\u1eddi ti\u1ebfp x\u00fac c\u1ee7a ng\u01b0\u1eddi nhi\u1ec5m b\u1ec7nh<\/li>\n<li>Theo d\u00f5i t\u00ecnh tr\u1ea1ng gi\u1ea3m oxy m\u00e1u th\u1ea7m l\u1eb7ng (t\u1ed5n th\u01b0\u01a1ng ph\u1ed5i) b\u1eb1ng c\u00e1ch \u0111o oxy m\u00e1u \u0111\u1ea7u ng\u00f3n tay (theo d\u00f5i \u0111\u1ed9 b\u00e3o h\u00f2a oxy)<\/li>\n<li>Ch\u1ea9n \u0111o\u00e1n c\u00e1c m\u1ea7m b\u1ec7nh trong d\u00f2ng m\u00e1u, x\u00e1c \u0111\u1ecbnh kh\u1ea3 n\u0103ng kh\u00e1ng thu\u1ed1c kh\u00e1ng vi sinh v\u1eadt v\u00e0 \u0111\u1ea9y nhanh qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb nh\u1eafm m\u1ee5c ti\u00eau cho b\u1ec7nh \u0111\u1ed3ng nhi\u1ec5m v\u00e0 nhi\u1ec5m tr\u00f9ng huy\u1ebft<\/li>\n<li>X\u00e1c \u0111\u1ecbnh giai \u0111o\u1ea1n b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m tr\u00f9ng ph\u1ed5i, v\u00e0 nh\u1eefng ng\u01b0\u1eddi b\u1ecb b\u1ec7nh n\u1eb7ng c\u00f3 h\u1ed9i ch\u1ee9ng suy h\u00f4 h\u1ea5p c\u1ea5p ti\u1ebfn tri\u1ec3n (acute respiratory distress syndrome, ARDS)<\/li>\n<li>\u0110o kh\u00ed m\u00e1u \u0111\u1ed9ng m\u1ea1ch v\u00e0 v\u1edbi FiO2 h\u00edt v\u00e0o, x\u00e1c \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a ARDS b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng t\u1ef7 l\u1ec7 P\/F (PaO2\/FiO2): &gt; 200, nh\u1eb9; 100-200, trung b\u00ecnh; v\u00e0 &lt; 100, n\u1eb7ng<\/li>\n<li>\u0110\u00e1nh gi\u00e1 t\u1ea3i l\u01b0\u1ee3ng c\u1ee7a vi-r\u00fat trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb d\u01b0\u1ee3c l\u00fd, kh\u1ea3 n\u0103ng mi\u1ec5n d\u1ecbch IgG v\u00e0 IgM trong qu\u00e1 tr\u00ecnh thuy\u00ean gi\u1ea3m v\u00e0 chu\u1ea9n \u0111\u1ed9 kh\u00e1ng th\u1ec3 sau khi ti\u00eam ch\u1ee7ng<\/li>\n<\/ul>\n<h3 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 24px !important; line-height: 32px !important; letter-spacing: 0px !important;\">C\u00e1c ch\u00ednh ph\u1ee7 v\u00e0 nh\u00e0 ho\u1ea1ch \u0111\u1ecbnh ch\u00ednh s\u00e1ch c\u00f3 th\u1ec3 h\u1ed7 tr\u1ee3 vi\u1ec7c s\u1eed d\u1ee5ng POCT cho COVID-19 nh\u01b0 th\u1ebf n\u00e0o?<\/h3>\n<p>C\u00e1c ch\u00ednh ph\u1ee7 v\u00e0 nh\u00e0 ho\u1ea1ch \u0111\u1ecbnh ch\u00ednh s\u00e1ch n\u00ean t\u00e0i tr\u1ee3 cho vi\u1ec7c nghi\u00ean c\u1ee9u v\u00e0 ph\u00e1t tri\u1ec3n POCT \u0111\u1ec3 ph\u00e1t hi\u1ec7n b\u1ec7nh, \u0111\u00e1nh gi\u00e1 \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch v\u00e0 ph\u00e1t tri\u1ec3n c\u00e1c chi\u1ebfn l\u01b0\u1ee3c \u0111\u1ec3 gh\u00e9p ch\u1ea9n \u0111o\u00e1n v\u1edbi c\u00e1c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb. H\u1ecd n\u00ean cung c\u1ea5p c\u00e1c c\u01a1 ch\u1ebf t\u00e0i tr\u1ee3 v\u00e0 th\u00fac \u0111\u1ea9y c\u00e1c m\u00f4 h\u00ecnh kinh doanh \u0111\u1ec3 gi\u00fap c\u00e1c c\u00f4ng ty kh\u1edfi nghi\u1ec7p ph\u00e1t minh ra POCT m\u1edbi cho SARS-CoV-2. H\u1ecd c\u1ea7n so\u1ea1n ra c\u00e1c h\u01b0\u1edbng d\u1eabn qu\u1ed1c gia v\u1ec1 x\u00e9t nghi\u1ec7m v\u00e0 cung c\u1ea5p quy\u1ec1n ti\u1ebfp c\u1eadn x\u00e9t nghi\u1ec7m mi\u1ec5n ph\u00ed cho c\u00f4ng ch\u00fang. \u0110i\u1ec1u quan tr\u1ecdng l\u00e0 h\u1ecd n\u00ean ph\u00e1t \u0111\u1ed9ng c\u00e1c chi\u1ebfn d\u1ecbch y t\u1ebf c\u00f4ng c\u1ed9ng \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o c\u00f4ng ch\u00fang hi\u1ec3u \u0111\u01b0\u1ee3c m\u1ee5c \u0111\u00edch c\u1ee7a POCT trong gi\u00e1m s\u00e1t d\u1ecbch b\u1ec7nh, truy v\u1ebft v\u00e0 qu\u1ea3n l\u00fd ng\u01b0\u1eddi ti\u1ebfp x\u00fac.<\/p>\n<h3 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 24px !important; line-height: 32px !important; letter-spacing: 0px !important;\">Ch\u00fang ta c\u00f3 th\u1ec3 h\u1ecdc h\u1ecfi g\u00ec t\u1eeb nh\u1eefng \u0111\u1ea1i d\u1ecbch tr\u01b0\u1edbc \u0111\u00e2y \u0111\u1ec3 \u0111\u1ecbnh h\u01b0\u1edbng vai tr\u00f2 c\u1ee7a c\u00e1c chi\u1ebfn l\u01b0\u1ee3c POC trong vi\u1ec7c \u1ee9ng ph\u00f3 v\u1edbi COVID-19?<\/h3>\n<p>D\u1ecbch Ebola \u1edf T\u00e2y Phi \u0111\u00e3 d\u1ea1y cho ch\u00fang ta nh\u1eefng b\u00e0i h\u1ecdc quan tr\u1ecdng trong vi\u1ec7c chu\u1ea9n b\u1ecb cho cu\u1ed9c kh\u1ee7ng ho\u1ea3ng COVID-19, nh\u01b0ng nh\u1eefng l\u1eddi khuy\u00ean, chi\u1ebfn l\u01b0\u1ee3c v\u00e0 ph\u00e1t tri\u1ec3n c\u00f4ng ngh\u1ec7 \u2013 \u0111\u1eb7c bi\u1ec7t l\u00e0 trong l\u0129nh v\u1ef1c POCT \u2013 h\u1ea7u h\u1ebft b\u1ecb b\u1ecf qua. Ch\u00fang ta ph\u1ea3i h\u00e0nh \u0111\u1ed9ng \u0111\u1ec3 vi\u1ec7c n\u00e0y kh\u00f4ng t\u00e1i di\u1ec5n. \u0110\u1ec3 bi\u1ebft th\u00eam th\u00f4ng tin, vui l\u00f2ng tham kh\u1ea3o X\u00e9t nghi\u1ec7m T\u1ea1i ch\u1ed7 To\u00e0n c\u1ea7u \u2013 C\u00e1c Chi\u1ebfn l\u01b0\u1ee3c d\u00e0nh cho Th\u1ea3m h\u1ecda, Tr\u01b0\u1eddng h\u1ee3p Kh\u1ea9n c\u1ea5p v\u00e0 T\u00ednh b\u1ec1n b\u1ec9 c\u1ee7a Y t\u1ebf C\u00f4ng c\u1ed9ng, c\u0169ng nh\u01b0 c\u00e1c t\u00e0i li\u1ec7u tham kh\u1ea3o 7 v\u00e0 8 d\u01b0\u1edbi \u0111\u00e2y. H\u01b0\u1edbng d\u1eabn Th\u1ef1c d\u1ee5ng v\u1ec1 X\u00e9t nghi\u1ec7m T\u1ea1i ch\u1ed7 To\u00e0n c\u1ea7u c\u1ee7a Ti\u1ebfn s\u0129 Mark Shephard c\u0169ng cung c\u1ea5p c\u00e1c th\u00f4ng tin c\u00f3 gi\u00e1 tr\u1ecb.<\/p>\n<h3 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 24px !important; line-height: 32px !important; letter-spacing: 0px !important;\">C\u00e1c t\u1ed5 ch\u1ee9c gi\u00e1o d\u1ee5c c\u00f3 th\u1ec3 l\u00e0m g\u00ec \u0111\u1ec3 h\u1ed7 tr\u1ee3 \u0111\u00e0o t\u1ea1o v\u1ec1 c\u00f4ng ngh\u1ec7 v\u00e0 th\u1ef1c h\u00e0nh POCT?<\/h3>\n<p>Tr\u01b0\u1eddng h\u1ecdc v\u1ec1 y t\u1ebf c\u00f4ng c\u1ed9ng ph\u1ea3i hi\u1ec7n \u0111\u1ea1i h\u00f3a ch\u01b0\u01a1ng tr\u00ecnh gi\u1ea3ng d\u1ea1y \u0111\u1ec3 \u0111\u01b0a \u0111\u00e0o t\u1ea1o v\u1ec1 POCT v\u00e0o ch\u01b0\u01a1ng tr\u00ecnh. \u0110\u1ea1i d\u1ecbch COVID-19 \u0111\u00e3 ch\u1ee9ng minh r\u00f5 r\u00e0ng r\u1eb1ng c\u00e1c chi\u1ebfn l\u01b0\u1ee3c POCT l\u00e0 c\u1ea7n thi\u1ebft \u0111\u1ec3 ph\u00e1t hi\u1ec7n tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m b\u1ec7nh, truy v\u1ebft ng\u01b0\u1eddi ti\u1ebfp x\u00fac v\u00e0 t\u00e0i li\u1ec7u h\u00f3a ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch khi m\u1ecdi ng\u01b0\u1eddi mu\u1ed1n tr\u1edf l\u1ea1i l\u00e0m vi\u1ec7c. V\u00ec POCT ch\u01b0a \u0111\u01b0\u1ee3c nh\u1ea5n m\u1ea1nh trong gi\u00e1o d\u1ee5c y t\u1ebf c\u00f4ng c\u1ed9ng, ch\u00fang ta \u0111\u00e3 chu\u1ea9n b\u1ecb kh\u00f4ng \u0111\u1ea7y \u0111\u1ee7 trong vi\u1ec7c tri\u1ec3n khai POCT gi\u1eefa cu\u1ed9c kh\u1ee7ng ho\u1ea3ng y t\u1ebf c\u00f4ng c\u1ed9ng l\u1edbn nh\u1ea5t th\u1ebf k\u1ef7. \u0110\u1ec3 th\u1ea3o lu\u1eadn th\u00eam v\u1ec1 c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh h\u1ecdc v\u00e0 c\u1ea5p ch\u1ee9ng ch\u1ec9 v\u1ec1 POCT trong l\u0129nh v\u1ef1c y t\u1ebf c\u00f4ng c\u1ed9ng, vui l\u00f2ng tham kh\u1ea3o t\u00e0i li\u1ec7u tham kh\u1ea3o 5 v\u00e0 6 d\u01b0\u1edbi \u0111\u00e2y.<\/p>\n<h3 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 24px !important; line-height: 32px !important; letter-spacing: 0px !important;\">C\u00e1c h\u1ec7 th\u1ed1ng POCT c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o \u0111\u1ec3 chu\u1ea9n b\u1ecb cho \u0111\u1ea1i d\u1ecbch ti\u1ebfp theo?<\/h3>\n<p>C\u00e1c qu\u1ed1c gia v\u1eabn ch\u01b0a s\u1eb5n s\u00e0ng cho \u0111\u1ea1i d\u1ecbch ti\u1ebfp theo. Th\u1ebf gi\u1edbi \u0111\u00e3 \u0111\u1ed5i thay v\u00e0 nghi\u1ec7p v\u1ee5 POC c\u0169ng ph\u1ea3i thay \u0111\u1ed5i theo. M\u1ed9t c\u00e1ch \u0111\u1ec3 th\u1ef1c hi\u1ec7n thay \u0111\u1ed5i l\u00e0 th\u00f4ng qua \u201ckhoa h\u1ecdc x\u00e9t nghi\u1ec7m t\u1ea1i ch\u1ed7\u201d, m\u1ed9t kh\u00e1i ni\u1ec7m m\u1edbi l\u1ea1 v\u00e0 th\u1ef1c ti\u1ec5n cho t\u01b0\u01a1ng lai. \u0110\u01b0\u1ee3c ph\u00e1t tri\u1ec3n t\u1ea1i Trung Qu\u1ed1c b\u1edfi m\u1ed9t nh\u00f3m do Gi\u00e1o s\u01b0 Xiguang Liu l\u00e3nh \u0111\u1ea1o t\u1ea1i V\u0169 H\u00e1n, khoa h\u1ecdc x\u00e9t nghi\u1ec7m t\u1ea1i ch\u1ed7 l\u00e0 m\u1ed9t ng\u00e0nh y t\u1ebf m\u1edbi n\u1ed5i t\u1eadp trung v\u00e0o vai tr\u00f2 c\u1ee7a POCT \u0111\u1ec3 nhanh ch\u00f3ng \u0111\u01b0a ra k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m, \u0111\u1ea9y nhanh qu\u00e1 tr\u00ecnh ra quy\u1ebft \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb v\u00e0 gi\u1ea3m g\u00e1nh n\u1eb7ng kinh t\u1ebf c\u1ee7a ng\u00e0nh y t\u1ebf. POCT nhanh ch\u00f3ng, ch\u00ednh x\u00e1c v\u00e0 an to\u00e0n s\u1ebd cho ph\u00e9p c\u00e1c qu\u1ed1c gia s\u1edbm ng\u0103n ch\u1eb7n s\u1ef1 b\u00f9ng ph\u00e1t d\u1ecbch b\u1ec7nh truy\u1ec1n nhi\u1ec5m ti\u1ebfp theo tr\u01b0\u1edbc khi d\u1ecbch b\u1ec7nh lan r\u1ed9ng tr\u00ean to\u00e0n th\u1ebf gi\u1edbi. <img decoding=\"async\" class=\" size-full wp-image-84740\" src=\"\/wp-content\/uploads\/2020\/08\/Kost-image2-2ff-scaled.jpg\" alt=\"Kostimage2 \" width=\"2560\" height=\"1920\" data-entity-type=\"file\" data-entity-uuid=\"35646207-b3f0-4a8e-90ee-5e7ac6d17ed0\" title=\"\" srcset=\"https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image2-2ff-scaled.jpg 2560w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image2-2ff-268x201.jpg 268w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image2-2ff-1024x768.jpg 1024w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image2-2ff-768x576.jpg 768w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image2-2ff-1536x1152.jpg 1536w, https:\/\/labinsights.com\/app\/uploads\/2020\/08\/Kost-image2-2ff-2048x1536.jpg 2048w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/><\/p>\n<h3 class=\"text-align-justify\" style=\"font-family: Inter !important; font-weight: 500 !important; font-size: 24px !important; line-height: 32px !important; letter-spacing: 0px !important;\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h3>\n<p>[1]\u00a0Kost GJ. Designing and interpreting COVID-19 diagnostics: Mathematics, visual logistics, and low prevalence. Archives of Pathology and Laboratory Medicine. 2020. [open access]<\/p>\n<p>[2] Kost GJ. \u00a0Geospatial spread of antimicrobial resistance, bacterial and fungal threats to COVID-19 survival, and point-of-care solutions. Archives of Pathology and Laboratory Medicine. 2020. [open access]<\/p>\n<p>[3] Kost GJ. Geospatial hotspots need point-of-care strategies to help stop highly infectious outbreaks: Ebola and Coronavirus-19. Archives of Pathology and Laboratory Medicine. 2020. [open access]<\/p>\n<p>[4] Liu X, Zhu X, Kost GJ et al. The creation of point-of-careology. Point of Care. 2019;18(3):77-84. [open access]<\/p>\n<p>[5] Kost GJ. Geospatial science and point-of-care testing: Creating solutions for population access, emergencies, outbreaks, and disasters. \u00a0Frontiers in Public Health. 2019;7:329. [open access]<\/p>\n<p>[6] Kost GJ, et al. POCT curriculum and accreditation for public health: Enabling preparedness, response, and higher standards of care at points of need. Frontiers in Public Health. 2019;6:385. [open access]<\/p>\n<p>[7] Kost GJ. Molecular and point-of-care diagnostics for Ebola and new threats: National POCT policy and guidelines will stop epidemics. Expert Review of Molecular Diagnostics. 2018;18(7):657-673.<\/p>\n<p>[8] Kost GJ et al. Molecular detection and point-of-care testing in Ebola virus disease and other threats: a new global public health framework to stop outbreaks. Expert Review of Molecular Diagnostics. 2015;15(10):1245-1259.<\/p>\n<p>[9] Kost GJ, Curtis CM, Eds. Global Point of Care \u2014 Strategies for Disasters, Emergencies, and Public Health Resiliency. Washington DC: AACC Press-Elsevier, 2015. [contributed book, 701 pp.]<\/p>\n<p>[10] Food and Drug Administration, United States. In vitro diagnostics EUAs. https:\/\/www.fda.gov\/medical-devices\/coronavirus-disease-2019-covid-19-emergency-use-authorizations-medical-devices\/vitro-diagnostics-euas <strong>L\u1eddi c\u1ea3m \u01a1n<\/strong> C\u00f4ng tr\u00ecnh n\u00e0y \u0111\u01b0\u1ee3c h\u1ed7 tr\u1ee3 b\u1edfi Point-of-Care Testing Center for Teaching and Research (POCT\u2022CTR) v\u00e0 Ti\u1ebfn s\u0129 Kost, Gi\u00e1m \u0111\u1ed1c c\u1ee7a trung t\u00e2m. S\u1ed1 li\u1ec7u v\u00e0 b\u1ea3ng \u0111\u01b0\u1ee3c cung c\u1ea5p theo s\u1ef1 gi\u00fap \u0111\u1ee1 v\u00e0 s\u1ef1 cho ph\u00e9p c\u1ee7a Knowledge Optimization, Davis, California.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>V\u1edbi t\u01b0 c\u00e1ch l\u00e0 Gi\u00e1m \u0111\u1ed1c Point-of-Care Testing Center for Teaching and Research (POCT\u2022CTR) v\u00e0 Gi\u00e1o s\u01b0 Danh d\u1ef1 v\u1ec1 B\u1ec7nh h\u1ecdc v\u00e0 Y h\u1ecdc Ph\u00f2ng x\u00e9t nghi\u1ec7m t\u1ea1i University of California Davis School of Medicine, Ti\u1ebfn s\u0129 Gerald Kost l\u00e0 m\u1ed9t trong nh\u1eefng chuy\u00ean gia h\u00e0ng \u0111\u1ea7u th\u1ebf gi\u1edbi v\u1ec1 x\u00e9t nghi\u1ec7m t\u1ea1i ch\u1ed7 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":84758,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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