{"id":147340,"date":"2021-08-04T03:57:33","date_gmt":"2021-08-04T03:57:33","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/chan-doan-tinh-trang-dong-mau-giup-quan-ly-tiem-chung-covid-19-va-xu-tri-benh-nhan-nhu-the-nao\/"},"modified":"2026-02-24T10:30:05","modified_gmt":"2026-02-24T10:30:05","slug":"how-coagulation-diagnostics-support-covid-19-vaccination-and-patient-management","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/vi\/disease-area\/coagulation\/how-coagulation-diagnostics-support-covid-19-vaccination-and-patient-management\/","title":{"rendered":"Ch\u1ea9n \u0111o\u00e1n ti\u0300nh tra\u0323ng \u0111\u00f4ng m\u00e1u giu\u0301p qua\u0309n ly\u0301 ti\u00eam ch\u1ee7ng COVID-19 v\u00e0 x\u01b0\u0309 tri\u0301 b\u1ec7nh nh\u00e2n nh\u01b0 th\u1ebf n\u00e0o"},"content":{"rendered":"

Nhi\u00ea\u0303m COVID-19 c\u00f3 li\u00ean quan \u0111\u1ebfn t\u00ecnh tr\u1ea1ng hi\u0300nh tha\u0300nh huy\u1ebft kh\u1ed1i, ho\u1eb7c c\u1ee5c m\u00e1u \u0111\u00f4ng, \u01a1\u0309 ca\u0301c t\u0129nh m\u1ea1ch v\u00e0 \u0111\u1ed9ng m\u1ea1ch. Nguy c\u01a1 h\u00ecnh th\u00e0nh nh\u01b0\u0303ng c\u1ee5c m\u00e1u \u0111\u00f4ng cao nh\u1ea5t \u0111\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi nh\u1eadp vi\u1ec7n do nhi\u1ec5m COVID-19, x\u1ea3y ra \u1edf kho\u1ea3ng 5% s\u1ed1 b\u00ea\u0323nh nh\u00e2n nh\u1eadp vi\u1ec7n t\u1ea1i c\u00e1c khoa b\u1ec7nh th\u00f4ng th\u01b0\u1eddng v\u00e0 l\u00ean t\u1edbi 20% \u0111\u1ed1i v\u1edbi nh\u1eefng b\u00ea\u0323nh nh\u00e2n \u1edf \u0111\u01a1n vi\u0323 ch\u0103m so\u0301c ti\u0301ch c\u01b0\u0323c (ICU), \u0111ang s\u01b0\u0309 du\u0323ng ca\u0301c thi\u00ea\u0301t bi\u0323 h\u1ed7 tr\u1ee3 s\u1ef1 s\u1ed1ng. Nguy c\u01a1 h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng \u1edf nh\u1eefng ng\u01b0\u1eddi m\u1eafc COVID-19 nh\u01b0ng ch\u01b0a pha\u0309i nh\u1eadp vi\u1ec7n th\u1ea5p h\u01a1n, \u1edf m\u1ee9c kho\u1ea3ng 1% [1].<\/p>\n

M\u1eb7c d\u00f9 kh\u00f4ng ph\u1ed5 bi\u1ebfn, vi\u1ec7c ti\u00eam v\u1eafc-xin c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb adenovirus c\u0169ng li\u00ean quan \u0111\u1ebfn kha\u0309 n\u0103ng hi\u0300nh tha\u0300nh nh\u01b0\u0303ng m\u00e1u \u0111\u00f4ng th\u00f4ng qua qua\u0301 tri\u0300nh gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i do v\u1eafc-xin (VITT). \u0110\u1ec3 hi\u1ec3u r\u00f5 h\u01a1n v\u1ec1 c\u00e1c nguy c\u01a1 chi\u0301nh li\u00ean quan \u0111\u00ea\u0301n \u0111\u00f4ng m\u00e1u v\u00e0 vi\u00ea\u0323c c\u00e2n nh\u1eafc ti\u00eam ch\u1ee7ng COVID-19 v\u00e0 qu\u1ea3n l\u00fd b\u1ec7nh nh\u00e2n, Roche Diagnostics Ch\u00e2u \u00c1 Th\u00e1i B\u00ecnh D\u01b0\u01a1ng g\u1ea7n \u0111\u00e2y \u0111\u00e3 trao \u0111\u1ed5i v\u1edbi Ba\u0301c si\u0303 Ng Heng Joo, C\u1ed1 v\u1ea5n c\u1ea5p cao & Tr\u01b0\u1edfng khoa Huy\u1ebft h\u1ecdc t\u1ea1i B\u1ec7nh vi\u1ec7n \u0110a khoa Singapore.<\/p>\n

C\u00e1c d\u1ea5u \u1ea5n \u0111\u00f4ng m\u00e1u trong ch\u0103m s\u00f3c COVID-19 v\u00e0 \u0111\u00e1nh gi\u00e1 sau ti\u00eam ch\u1ee7ng<\/h3>\n

Nga\u0300y ca\u0300ng nhi\u00ea\u0300u c\u00e1c b\u1eb1ng ch\u1ee9ng \u0111\u01b0\u01a1\u0323c ti\u0300m th\u00e2\u0301y trong ph\u00f2ng th\u00ed nghi\u1ec7m cho th\u00e2\u0301y nh\u1eefng thay \u0111\u1ed5i b\u1ea5t th\u01b0\u1eddng v\u1ec1 \u0111\u00f4ng m\u00e1u \u1edf b\u1ec7nh nh\u00e2n nhi\u1ec5m COVID-19 c\u00f3 th\u1ec3 l\u00e0 k\u1ebft qu\u1ea3 c\u1ee7a ph\u1ea3n \u1ee9ng vi\u00eam n\u0103\u0323ng n\u00ea\u0300 ke\u0301o da\u0300i ch\u1ee9 kh\u00f4ng li\u00ean quan \u0111\u1ebfn kha\u0309 n\u0103ng \u0111\u00f4ng m\u00e1u n\u1ed9i t\u1ea1i. S\u1ef1 gia t\u0103ng \u0111\u00e1ng k\u1ec3 c\u00e1c protein g\u00e2y \u0111\u00f4ng m\u00e1u c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb nhi\u1ec5m COVID-19 n\u1eb7ng, t\u01b0\u01a1ng \u01b0\u0301ng v\u1edbi ph\u1ea3n \u1ee9ng cu\u0309a giai \u0111o\u1ea1n c\u1ea5p t\u00ednh n\u0103\u0323ng n\u00ea\u0300. M\u1ed9t nho\u0301m nh\u1ecf b\u1ec7nh nh\u00e2n co\u0301 vi\u00eam ph\u1ed5i n\u1eb7ng \u0111\u00e3 ti\u00ea\u0301n tri\u00ea\u0309n tha\u0300nh nhi\u1ec5m tr\u00f9ng huy\u1ebft do virus, \u0111\u00f4ng m\u00e1u n\u1ed9i m\u1ea1ch r\u1ea3i r\u00e1c (DIC), v\u00e0 suy \u0111a t\u1ea1ng.<\/p>\n

V\u00ec D-Dimer l\u00e0 d\u1ea5u hi\u1ec7u d\u01b0\u01a1ng t\u00ednh \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n b\u1ecb huy\u1ebft kh\u1ed1i n\u00ean \u0111\u00e3 c\u00f3 nhi\u1ec1u nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n nh\u1eb1m c\u1ed1 g\u1eafng k\u1ebft h\u1ee3p D-Dimer v\u00e0o vi\u1ec7c d\u1ef1 \u0111o\u00e1n m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a COVID-19. “D-Dimer \u0111\u00e3 tr\u01a1\u0309 tha\u0300nh m\u00f4\u0323t trong nh\u01b0\u0303ng ti\u00eau chi\u0301 trong thang \u0111i\u00ea\u0309m \u0111\u00e1nh gi\u00e1 nguy c\u01a1 ph\u00e1t tri\u1ec3n huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch \u1edf b\u1ec7nh nh\u00e2n COVID-19”, B\u00e1c s\u0129 Ng. l\u01b0u \u00fd. “C\u00f3 m\u1ed9t ch\u00fat kh\u00f3 kh\u0103n trong vi\u1ec7c x\u00e1c \u0111\u1ecbnh c\u00e1c ng\u01b0\u1ee1ng lo nga\u0323i v\u1ec1 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh v\u00e0 m\u1ee9c \u0111\u1ed9 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c t\u0103ng ng\u01b0\u01a1\u0303ng \u0111i\u00ea\u0300u tri\u0323 cho b\u1ec7nh nh\u00e2n.”<\/p>\n

“M\u1ed9t s\u1ed1 v\u00ed d\u1ee5 ph\u1ed5 bi\u1ebfn v\u1ec1 c\u00e1c m\u00f4 h\u00ecnh \u0111\u00e1nh gi\u00e1 nguy c\u01a1 \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng bao g\u1ed3m \u0111i\u1ec3m ca\u0309i thi\u00ea\u0323n D-Dimer cu\u0303ng nh\u01b0 ch\u1ec9 s\u1ed1 Caprini”, \u00f4ng cho bi\u1ebft th\u00eam. “\u0110\u00e3 c\u00f3 m\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u x\u00e1c nh\u1eadn cho th\u1ea5y chi\u0309 s\u00f4\u0301 na\u0300y giu\u0301p th\u01b0\u0323c hi\u00ea\u0323n kh\u00e1 t\u1ed1t vi\u1ec7c d\u1ef1 \u0111o\u00e1n b\u1ec7nh nh\u00e2n n\u00e0o c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e2n lo\u1ea1i l\u00e0 nguy c\u01a1 th\u1ea5p, nguy c\u01a1 trung b\u00ecnh ho\u1eb7c nguy c\u01a1 cao hi\u0300nh tha\u0300nh huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch v\u00e0 t\u1eeb \u0111\u00f3 ma\u0300 \u0111\u01b0a ra ca\u0301ch s\u1eed d\u1ee5ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u th\u00edch h\u1ee3p cho b\u1ec7nh nh\u00e2n.”<\/p>\n

\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n VITT (gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i do v\u1eafc-xin), x\u00e9t nghi\u1ec7m th\u01b0\u1eddng cho th\u1ea5y n\u1ed3ng \u0111\u1ed9 fibrinogen th\u1ea5p v\u00e0 D-Dimer t\u0103ng r\u1ea5t cao tr\u00ean m\u1ee9c chu\u00e2\u0309n trong hi\u0300nh tha\u0300nh huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch. “Ch\u00fang t\u00f4i bi\u1ebft kh\u1ea3 n\u0103ng VITT (gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i do v\u1eafc-xin) kh\u1edfi ph\u00e1t th\u01b0\u1eddng trong kho\u1ea3ng t\u1eeb 5 \u0111\u1ebfn 28 ng\u00e0y sau khi ti\u00eam ch\u1ee7ng”, Ba\u0301c si\u0303 Ng. nh\u1ea5n m\u1ea1nh. “Ch\u00fang t\u00f4i bi\u1ebft r\u1eb1ng COVID-19 g\u00e2y ra huy\u1ebft kh\u1ed1i \u01a1\u0309 nh\u01b0\u0303ng vi\u0323 tri\u0301 b\u00e2\u0301t th\u01b0\u01a1\u0300ng nh\u01b0 huy\u1ebft kh\u1ed1i xoang t\u0129nh m\u1ea1ch n\u00e3o c\u0169ng nh\u01b0 huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch l\u00e1ch.”<\/p>\n

Kh\u00e1ng th\u1ec3 kh\u00e1ng y\u1ebfu t\u1ed1 ti\u1ec3u c\u1ea7u 4 (PF4) \u0111\u00e3 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh \u1edf b\u1ec7nh nh\u00e2n VITT (gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i do v\u1eafc-xin), do \u0111\u00f3 c\u00f3 s\u1ef1 t\u01b0\u01a1ng \u0111\u1ed3ng v\u1edbi gi\u1ea3m ti\u1ec3u c\u1ea7u do heparin (HIT) m\u1eb7c d\u00f9 kh\u00f4ng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng heparin tr\u01b0\u1edbc \u0111\u00f3. Kh\u00e1ng th\u1ec3 kh\u00e1ng PF4 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n b\u1eb1ng x\u00e9t nghi\u1ec7m ELISA HIT nh\u01b0ng \u0111\u00e2y th\u01b0\u1eddng kh\u00f4ng pha\u0309i l\u00e0 v\u1edbi c\u00e1c x\u00e9t nghi\u1ec7m ki\u00ea\u0309m tra nhanh, ma\u0300 th\u01b0\u1eddng d\u1ef1a tr\u00ean s\u1ef1 ph\u00e1t quang h\u00f3a h\u1ecdc c\u0169ng nh\u01b0 c\u00e1c x\u00e9t nghi\u1ec7m latex.<\/p>\n

Nh\u1eefng th\u00e1ch th\u1ee9c trong x\u00e9t nghi\u1ec7m \u0111\u00f4ng m\u00e1u trong th\u1eddi ky\u0300 COVID-19<\/h3>\n

Do co\u0301 li\u00ean quan v\u01a1\u0301i kha\u0309 n\u0103ng hi\u0300nh tha\u0300nh huy\u1ebft kh\u1ed1i, COVID-19 ch\u1eafc ch\u1eafn \u0111\u00e3 g\u00e2y ra nhi\u1ec1u th\u00e1ch th\u1ee9c<\/a> trong vi\u1ec7c ch\u1ea9n \u0111o\u00e1n v\u00e0 x\u1eed tr\u00ed b\u1ec7nh nh\u00e2n. Trong giai \u0111o\u1ea1n \u0111\u1ea7u c\u1ee7a \u0111\u1ea1i d\u1ecbch, m\u1ed9t trong nh\u1eefng th\u00e1ch th\u1ee9c n\u00e0y l\u00e0 hi\u1ec3u \u0111\u01b0\u1ee3c sinh l\u00fd b\u1ec7nh ho\u1eb7c vai tr\u00f2 c\u1ee7a huy\u1ebft kh\u1ed1i \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc COVID-19. V\u00ec v\u1eady vi\u1ec7c c\u1ed1 g\u1eafng ph\u00e2n t\u1ea7ng b\u00ea\u0323nh nh\u00e2n c\u00f3 nguy c\u01a1 cao v\u00e0 vai tr\u00f2 c\u1ee7a li\u1ec7u ph\u00e1p ch\u1ed1ng \u0111\u00f4ng cho nh\u00f3m b\u1ec7nh nh\u00e2n \u0111\u00f3 l\u00e0 m\u1ed9t th\u00e1ch th\u1ee9c.<\/p>\n

M\u1ed9t th\u00e1ch th\u1ee9c kh\u00e1c trong ch\u00e2\u0309n \u0111oa\u0301n la\u0300 s\u01b0\u0323 xu\u00e2\u0301t hi\u00ea\u0323n cu\u0309a c\u1ee7a VITT ( gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i do v\u1eafc-xin). Trong khi x\u00e9t nghi\u1ec7m kh\u00e1ng th\u1ec3 kh\u00e1ng PF4 \u0111\u00e3 \u0111\u01b0\u1ee3c thi\u1ebft k\u00ea\u0301 t\u1ed1t \u0111\u00ea\u0309 pha\u0301t hi\u00ea\u0323n HIT, vi\u1ec7c s\u1eed d\u1ee5ng xe\u0301t nghi\u00ea\u0323m v\u00e0 \u0111\u1ed9 nh\u1ea1y c\u1ee7a xe\u0301t nghi\u00ea\u0323m \u01a1\u0309 b\u1ec7nh nh\u00e2n VITT (gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i do v\u1eafc-xin) l\u00e0 kh\u00e1c bi\u1ec7t v\u00e0 kh\u00e1c nhau. \u0110\u00ea\u0309 b\u1ed5 sung th\u00eam cho vi\u1ec7c ch\u1ee9ng minh co\u0301 kh\u00e1ng th\u1ec3 kha\u0301ng PF4, c\u00e1c x\u00e9t nghi\u1ec7m \u0111a\u0303 \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n \u0111\u1ec3 ti\u0300m ra s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a c\u00e1c kh\u00e1ng th\u1ec3 k\u00edch ho\u1ea1t ti\u1ec3u c\u1ea7u [2].<\/p>\n

Th\u00e1ch th\u1ee9c n\u00e0y d\u1eabn \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c x\u00e9t nghi\u1ec7m b\u1ed5 sung d\u01b0\u0323a tr\u00ean c\u01a1 s\u01a1\u0309 \u0111a\u0303 co\u0301 – v\u00ed d\u1ee5 nh\u01b0 x\u00e9t nghi\u1ec7m ki\u00ea\u0309m tra kha\u0309 n\u0103ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u cu\u0309a heparin (HIPAA). T\u01b0\u01a1ng t\u01b0\u0323 v\u01a1\u0301i m\u1ed9t x\u00e9t nghi\u1ec7m HIPAA ca\u0309i ti\u00ea\u0301n, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 ph\u00e1t tri\u1ec3n m\u1ed9t x\u00e9t nghi\u1ec7m k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u do y\u1ebfu t\u1ed1 ti\u1ec3u c\u1ea7u 4 g\u00e2y ra \u0111\u1ec3 c\u1ed1 g\u1eafng x\u00e1c \u0111\u1ecbnh r\u00f5 h\u01a1n nguy\u00ean nh\u00e2n ho\u1eb7c ch\u1ea9n \u0111o\u00e1n b\u1ec7nh nh\u00e2n m\u1eafc VITT (gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i do v\u1eafc-xin) \u0111u\u0301ng h\u01a1n. S\u1ef1 ho\u1ea1t h\u00f3a ti\u1ec3u c\u1ea7u ho\u1eb7c c\u00e1c kh\u00e1ng th\u1ec3 b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p \u0111\u1ebfm t\u1ebf b\u00e0o co\u0301 trong d\u00f2ng ch\u1ea3y \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u00ea\u0309 ki\u00ea\u0309m tra trong ph\u00f2ng x\u00e9t nghi\u1ec7m. C\u00e1c x\u00e9t nghi\u1ec7m n\u00e0y v\u01b0\u0300a h\u01b0\u0303u i\u0301ch v\u01b0\u0300a kho\u0301 kh\u0103n \u0111\u1ec3 ph\u00e1t tri\u1ec3n nghi\u00ean c\u01b0\u0301u nh\u01b0ng ch\u00fang \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh vai tro\u0300 trong ch\u1ea9n \u0111o\u00e1n VITT (gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i do v\u1eafc-xin).<\/p>\n

M\u1ed9t th\u01a1\u0300i \u0111a\u0323i m\u1edbi cu\u0309a ch\u1ea9n \u0111o\u00e1n ti\u0300nh tra\u0323ng \u0111\u00f4ng m\u00e1u<\/h3>\n

B\u1ec7nh \u0111\u00f4ng m\u00e1u do COVID-19 ta\u0323o ra l\u00e0 m\u1ed9t th\u1ec3 b\u00ea\u0323nh ri\u00eang bi\u1ec7t v\u01a1\u0301i s\u1ef1 t\u0103ng cao r\u00f5 r\u1ec7t c\u1ee7a D-Dimer. COVID-19 li\u00ean quan \u0111\u1ebfn nguy c\u01a1 cao huy\u1ebft kh\u1ed1i vi m\u1ea1ch v\u00e0 m\u1ea1ch m\u00e1u l\u1edbn v\u00e0 t\u0103ng t\u1ef7 l\u1ec7 th\u1ea5t b\u1ea1i khi s\u01b0\u0309 du\u0323ng ch\u1ed1ng \u0111\u00f4ng. Kh\u00f4ng gi\u1ed1ng nh\u01b0 nhi\u1ec5m tr\u00f9ng huy\u1ebft th\u00f4ng th\u01b0\u1eddng, thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u00f3ng m\u1ed9t vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c x\u01b0\u0309 tri\u0301 b\u00ea\u0323nh nh\u00e2n COVID-19<\/a> nh\u01a1\u0300 t\u00e1c \u0111\u1ed9ng t\u00edch c\u1ef1c \u0111\u1ebfn s\u1ef1 s\u1ed1ng c\u00f2n. C\u00e1c d\u1ea5u \u1ea5n sinh h\u1ecdc v\u00e0 h\u1ec7 th\u1ed1ng t\u00ednh \u0111i\u1ec3m kh\u00e1c nhau c\u00f3 th\u1ec3 h\u1eefu \u00edch trong vi\u1ec7c ph\u00e2n lo\u1ea1i b\u1ec7nh nh\u00e2n d\u01b0\u0323a va\u0300o c\u00e1c da\u0323ng nguy c\u01a1 t\u01b0\u01a1ng \u01b0\u0301ng v\u1edbi m\u1ee5c \u0111\u00edch s\u01b0\u0309 du\u0323ng ch\u1ed1ng \u0111\u00f4ng c\u0169ng nh\u01b0 ch\u1ea9n \u0111o\u00e1n ti\u0300nh tra\u0323ng hi\u0300nh tha\u0300nh c\u1ee5c m\u00e1u \u0111\u00f4ng sau ti\u00eam v\u0103\u0301c-xin trong th\u01a1\u0300i ky\u0300 COVID-19.<\/p>\n

T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/em><\/p>\n

[1]<\/a> C\u00e1c chuy\u00ean gia ISTH gi\u1ea3i th\u00edch hi\u1ec7n t\u01b0\u1ee3ng \u0111\u00f4ng m\u00e1u m\u1edbi \u1edf b\u1ec7nh nh\u00e2n COVID-19 nh\u1eadp vi\u1ec7n.<\/p>\n

[2]<\/a>\u00a0Scully, M. et al (2021). Kh\u00e1ng th\u1ec3 b\u1ec7nh l\u00fd kh\u00e1ng y\u1ebfu t\u1ed1 ti\u1ec3u c\u1ea7u 4 sau khi ti\u00eam ch\u1ee7ng ChAdOx1 nCoV-19. T\u1ea1p ch\u00ed Y h\u1ecdc New England. 384.pp2202-2211.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nhi\u00ea\u0303m COVID-19 c\u00f3 li\u00ean quan \u0111\u1ebfn t\u00ecnh tr\u1ea1ng hi\u0300nh tha\u0300nh huy\u1ebft kh\u1ed1i, ho\u1eb7c c\u1ee5c m\u00e1u \u0111\u00f4ng, \u01a1\u0309 ca\u0301c t\u0129nh m\u1ea1ch v\u00e0 \u0111\u1ed9ng m\u1ea1ch. Nguy c\u01a1 h\u00ecnh th\u00e0nh nh\u01b0\u0303ng c\u1ee5c m\u00e1u \u0111\u00f4ng cao nh\u1ea5t \u0111\u1ed1i v\u1edbi nh\u1eefng ng\u01b0\u1eddi nh\u1eadp vi\u1ec7n do nhi\u1ec5m COVID-19, x\u1ea3y ra \u1edf kho\u1ea3ng 5% s\u1ed1 b\u00ea\u0323nh nh\u00e2n nh\u1eadp vi\u1ec7n t\u1ea1i c\u00e1c khoa […]<\/p>\n","protected":false},"author":1,"featured_media":85245,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"tags":[14793,14843],"pillarandcategory":[292,285,282,317,286,309],"reporter":[14949,14950],"class_list":["post-147340","acf_article","type-acf_article","status-publish","has-post-thumbnail","hentry","tag-dong-mau","tag-xet-nghiem-mien-dich","pillarandcategory-coagulation","pillarandcategory-covid-19","pillarandcategory-disease-area","pillarandcategory-immunoassay","pillarandcategory-infectious-diseases","pillarandcategory-operations","reporter-niti-dawar","reporter-yingli-huang"],"acf":[],"_links":{"self":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147340","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article"}],"about":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/types\/acf_article"}],"author":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":3,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147340\/revisions"}],"predecessor-version":[{"id":149246,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/acf_article\/147340\/revisions\/149246"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media\/85245"}],"wp:attachment":[{"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/media?parent=147340"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/tags?post=147340"},{"taxonomy":"pillarandcategory","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/pillarandcategory?post=147340"},{"taxonomy":"reporter","embeddable":true,"href":"https:\/\/labinsights.com\/vi\/wp-json\/wp\/v2\/reporter?post=147340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}