{"id":147394,"date":"2020-03-05T10:57:14","date_gmt":"2020-03-05T10:57:14","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/thoi-gian-de-xem-xet-tieu-chuan-vang-de-tam-soat-ung-thu-co-tu-cung\/"},"modified":"2026-02-23T12:42:21","modified_gmt":"2026-02-23T12:42:21","slug":"time-to-review-the-gold-standard-for-cervical-cancer-screening","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/vi\/disease-area\/womens-health\/time-to-review-the-gold-standard-for-cervical-cancer-screening\/","title":{"rendered":"Th\u1eddi gian \u0111\u1ec3 xem x\u00e9t ti\u00eau chu\u1ea9n v\u00e0ng \u0111\u1ec3 t\u1ea7m so\u00e1t ung th\u01b0 c\u1ed5 t\u1eed cung"},"content":{"rendered":"

H\u01a1n 5.000 ph\u1ee5 n\u1eef \u1edf Th\u00e1i Lan t\u1eed vong m\u1ed7i n\u0103m do ung th\u01b0 c\u1ed5 t\u1eed cung [1],\u00a0theo b\u00e1o c\u00e1o n\u0103m 2019 t\u1eeb HPV Information Centre. 70% c\u00e1c tr\u01b0\u1eddng h\u1ee3p ung th\u01b0\u00a0n\u00e0y do hai ch\u1ee7ng HPV (human papillomavirus) g\u00e2y ra: HPV16 v\u00e0 HPV18. C\u1ea3 hai d\u00f2ng vi-r\u00fat n\u00e0y hi\u1ec7n \u0111\u1ec1u c\u00f3 th\u1ec3 ph\u00f2ng ng\u1eeba \u0111\u01b0\u1ee3c b\u1eb1ng v\u1eafc-xin, tuy nhi\u00ean HPV Information Centre \u01b0\u1edbc t\u00ednh ph\u1ea3i m\u1ea5t h\u00e0ng th\u1eadp k\u1ef7 m\u1edbi c\u00f3 th\u1ec3 c\u1ea3m nh\u1eadn \u0111\u01b0\u1ee3c h\u1ebft t\u00e1c \u0111\u1ed9ng c\u1ee7a v\u1eafc-xin. H\u01a1n n\u1eefa, do v\u1eafc-xin kh\u00f4ng th\u1ec3 ng\u0103n ng\u1eeba t\u1ea5t c\u1ea3 c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m HPV ho\u1eb7c ung th\u01b0, ph\u1ee5 n\u1eef v\u1eabn s\u1ebd c\u1ea7n ph\u1ea3i d\u1ef1a v\u00e0o vi\u1ec7c s\u00e0ng l\u1ecdc th\u01b0\u1eddng xuy\u00ean \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n s\u1edbm ung th\u01b0 c\u1ed5 t\u1eed cung<\/a>.\u00a0 Hi\u1ec7n nay, ph\u1ee5 n\u1eef \u0111\u01b0\u1ee3c kh\u00e1m s\u00e0ng l\u1ecdc b\u1eb1ng m\u1ed9t x\u00e9t nghi\u1ec7m \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong 70 n\u0103m qua. \u0110\u01b0\u1ee3c ph\u00e1t tri\u1ec3n b\u1edfi B\u00e1c s\u0129 George Nicholas Papanicolaou, ph\u1ebft t\u1ebf b\u00e0o c\u1ed5 t\u1eed cung c\u00f9ng t\u00ean l\u00e0 c\u00f4ng c\u1ee5 s\u00e0ng l\u1ecdc ti\u00eau chu\u1ea9n v\u00e0ng \u0111\u1ec3 ph\u00e1t hi\u1ec7n c\u00e1c t\u1ebf b\u00e0o v\u1ea3y b\u1ea5t th\u01b0\u1eddng \u1edf c\u1ed5 t\u1eed cung, ti\u1ec1n th\u00e2n c\u1ee7a b\u1ec7nh ung th\u01b0. Nh\u01b0ng v\u1edbi \u0111\u1ed9 nh\u1ea1y ch\u1ec9 tr\u00ean 55% [2]\u00a0v\u00e0 c\u00e1c c\u00f4ng c\u1ee5 s\u00e0ng l\u1ecdc m\u1edbi h\u01a1n, nh\u1ea1y c\u1ea3m h\u01a1n c\u00f3 s\u1eb5n, \u0111\u00e3 \u0111\u1ebfn l\u00fac r\u00fat lui ph\u01b0\u01a1ng ph\u00e1p c\u0169 n\u00e0y ch\u01b0a?<\/p>\n

X\u00e9t nghi\u1ec7m HPV ti\u00ean ph\u00e1t so v\u1edbi x\u00e9t nghi\u1ec7m Pap<\/h2>\n

K\u1ec3 t\u1eeb khi c\u00f3 x\u00e9t nghi\u1ec7m Pap, hi\u1ec3u bi\u1ebft c\u1ee7a ch\u00fang t\u00f4i v\u1ec1 ung th\u01b0 c\u1ed5 t\u1eed cung \u0111\u00e3 ti\u1ebfn tri\u1ec3n \u0111\u00e1ng k\u1ec3. Hi\u1ec7n nay ch\u00fang ta bi\u1ebft r\u1eb1ng HPV chia th\u00e0nh hai d\u00f2ng \u2013 vi-r\u00fat c\u00f3 nguy c\u01a1 cao bao g\u1ed3m HPV16 v\u00e0 18, c\u0169ng nh\u01b0 c\u00e1c ch\u1ee7ng \u00edt ph\u1ed5 bi\u1ebfn h\u01a1n nh\u01b0 31, 33, 45, 52, 58 v\u00e0 m\u1ed9t s\u1ed1 ch\u1ee7ng kh\u00e1c [3]\u00a0v\u00e0 c\u00e1c ch\u1ee7ng c\u00f3 nguy c\u01a1 th\u1ea5p, ch\u1eb3ng h\u1ea1n nh\u01b0 HPV6 v\u00e0 11, chi\u1ebfm kho\u1ea3ng 90% m\u1ee5n c\u00f3c sinh d\u1ee5c, nh\u01b0ng hi\u1ebfm khi ph\u00e1t tri\u1ec3n th\u00e0nh ung th\u01b0 [3].\u00a0Ph\u1ebft t\u1ebf b\u00e0o c\u1ed5 t\u1eed cung kh\u00f4ng ph\u00e2n bi\u1ec7t hai lo\u1ea1i n\u00e0y. Vi\u1ec7c kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng ph\u00e2n bi\u1ec7t gi\u1eefa c\u00e1c b\u1ea5t th\u01b0\u1eddng \u00e1c t\u00ednh v\u00e0 l\u00e0nh t\u00ednh s\u1ebd kh\u1edfi ph\u00e1t m\u1ed9t chu\u1ed7i c\u00e1c th\u0103m d\u00f2 ti\u1ebfp theo, r\u1ea5t nhi\u1ec1u trong s\u1ed1 \u0111\u00f3 l\u00e0 kh\u00f4ng c\u1ea7n thi\u1ebft v\u00e0 khi\u1ebfn ph\u1ee5 n\u1eef lo l\u1eafng. Nh\u01b0ng t\u1ea5t c\u1ea3 nh\u1eefng \u0111i\u1ec1u n\u00e0y \u0111ang d\u1ea7n thay \u0111\u1ed5i. N\u0103m 2014, C\u01a1 quan Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 \u0111\u00e3 ph\u00ea duy\u1ec7t x\u00e9t nghi\u1ec7m HPV \u0111\u1ea7u ti\u00ean [4]\u00a0\u0111\u1ec3 s\u00e0ng l\u1ecdc ung th\u01b0 c\u1ed5 t\u1eed cung. X\u00e9t nghi\u1ec7m d\u1ef1a tr\u00ean DNA n\u00e0y ph\u00e1t hi\u1ec7n th\u00e0nh c\u00f4ng s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a vi-r\u00fat HPV c\u00f3 nguy c\u01a1 cao \u1edf \u0111\u1ed9 nh\u1ea1y h\u01a1n 94% [2]. \u0110i\u1ec1u quan tr\u1ecdng kh\u00f4ng k\u00e9m l\u00e0 \u0111\u1ed9 tin c\u1eady cao c\u1ee7a k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m \u00e2m t\u00ednh. K\u1ebft qu\u1ea3 t\u1eeb m\u1ed9t nghi\u00ean c\u1ee9u n\u0103m 2009 \u1edf \u1ea4n \u0110\u1ed9 cho th\u1ea5y kh\u00f4ng c\u00f3 ph\u1ee5 n\u1eef n\u00e0o c\u00f3 k\u1ebft qu\u1ea3 \u00e2m t\u00ednh v\u1edbi HPV \u0111\u00e3 qua \u0111\u1eddi v\u00ec ung th\u01b0 c\u1ed5 t\u1eed cung trong th\u1eddi gian nghi\u00ean c\u1ee9u t\u00e1m n\u0103m [5]. C\u00e1c nghi\u00ean c\u1ee9u s\u00e2u h\u01a1n c\u0169ng b\u00e1o c\u00e1o t\u01b0\u01a1ng t\u1ef1 v\u1ec1 \u0111\u1ed9 an to\u00e0n c\u1ee7a k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m HPV \u00e2m t\u00ednh c\u00f3 nguy c\u01a1 cao trong ba n\u0103m. N\u0103m 2015, American Society for Colposcopy and Cervical Pathology (ASCCP) \u0111\u00e3 ban h\u00e0nh m\u1ed9t thu\u1eadt to\u00e1n s\u00e0ng l\u1ecdc m\u1edbi. B\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng x\u00e9t nghi\u1ec7m HPV c\u00f3 nguy c\u01a1 cao nh\u01b0 m\u1ed9t c\u00f4ng c\u1ee5 s\u00e0ng l\u1ecdc b\u01b0\u1edbc \u0111\u1ea7u, H\u1ed9i l\u1eadp lu\u1eadn r\u1eb1ng, theo d\u00f5i c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh ph\u00f9 h\u1ee3p v\u1edbi nhu c\u1ea7u c\u1ee7a t\u1eebng ph\u1ee5 n\u1eef, t\u1eeb \u0111\u00f3 lo\u1ea1i b\u1ecf vi\u1ec7c x\u00e9t nghi\u1ec7m kh\u00f4ng c\u1ea7n thi\u1ebft v\u00e0 cho ph\u00e9p c\u00e1c d\u1ecbch v\u1ee5 y t\u1ebf trong ph\u00f2ng x\u00e9t nghi\u1ec7m cung c\u1ea5p c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh s\u00e0ng l\u1ecdc k\u1ecbp th\u1eddi, c\u00f3 gi\u00e1 tr\u1ecb gia t\u0103ng v\u00e0 t\u1eadp trung. Th\u1ed5 Nh\u0129 K\u1ef3, H\u00e0 Lan v\u00e0 \u00dac l\u00e0 nh\u1eefng qu\u1ed1c gia \u0111\u1ea7u ti\u00ean th\u1ef1c hi\u1ec7n thay \u0111\u1ed5i ch\u01b0\u01a1ng tr\u00ecnh s\u00e0ng l\u1ecdc c\u1ee7a h\u1ecd.<\/p>\n

\"S\u00e0ng<\/p>\n

\u1edf Th\u00e1i Lan, Thai Gynecologic Cancer Society \u0111\u00e3 b\u1eaft tay v\u00e0o m\u1ed9t d\u1ef1 \u00e1n th\u00ed \u0111i\u1ec3m \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 m\u1ed9t thu\u1eadt to\u00e1n s\u00e0ng l\u1ecdc t\u01b0\u01a1ng t\u1ef1 v\u00e0o n\u0103m 2016. Hi\u1ec7p h\u1ed9i \u0111i\u1ec1u ch\u1ec9nh thu\u1eadt to\u00e1n ASCCP \u0111\u1ec3 ph\u00e2n bi\u1ec7t th\u00eam gi\u1eefa c\u00e1c ch\u1ee7ng HPV c\u00f3 nguy c\u01a1 cao kh\u00e1c v\u00e0 s\u1eeda \u0111\u1ed5i c\u00e1c kho\u1ea3ng th\u1eddi gian \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb \u0111\u1ec3 s\u00e0ng l\u1ecdc th\u01b0\u1eddng quy \u0111\u1ebfn m\u1ed7i ba n\u0103m. \u0110\u1ec3 x\u00e1c \u0111\u1ecbnh hi\u1ec7u qu\u1ea3 chi ph\u00ed c\u1ee7a ch\u01b0\u01a1ng tr\u00ecnh s\u00e0ng l\u1ecdc nh\u01b0 v\u1eady, ch\u00fang t\u00f4i \u0111\u00e3 m\u00f4 h\u00ecnh h\u00f3a v\u1ec1 m\u1eb7t to\u00e1n h\u1ecdc ba ph\u01b0\u01a1ng ph\u00e1p s\u00e0ng l\u1ecdc kh\u00e1c nhau: ph\u1ebft t\u1ebf b\u00e0o c\u1ed5 t\u1eed cung, x\u00e9t nghi\u1ec7m HPV c\u00f3 nguy c\u01a1 cao v\u00e0 t\u1eadp trung v\u00e0o ki\u1ec3u gen HPV16\/18 [6].\u00a0Ch\u00fang t\u00f4i \u0111\u00e3 k\u1ebft lu\u1eadn r\u1eb1ng x\u00e9t nghi\u1ec7m HPV c\u00f3 nguy c\u01a1 cao l\u00e0 c\u00f4ng c\u1ee5 s\u00e0ng l\u1ecdc hi\u1ec7u qu\u1ea3 nh\u1ea5t v\u1ec1 chi ph\u00ed. X\u00e9t nghi\u1ec7m HPV r\u1ebb h\u01a1n t\u1ebf b\u00e0o h\u1ecdc v\u00e0 ph\u00e1t hi\u1ec7n nhi\u1ec1u ung th\u01b0 c\u1ed5 t\u1eed cung giai \u0111o\u1ea1n s\u1edbm h\u01a1n so v\u1edbi ch\u1ec9 x\u00e9t nghi\u1ec7m t\u1ebf b\u00e0o h\u1ecdc. V\u00ec t\u1ef7 l\u1ec7 t\u1ea7m so\u00e1t ung th\u01b0 c\u1ed5 t\u1eed cung \u1edf Th\u00e1i Lan v\u1eabn th\u1ea5p \u1edf m\u1ee9c ch\u1ec9 50%, c\u00e1c \u0111\u1ed3ng nghi\u1ec7p t\u1ea1i Chulalongkorn University \u0111\u00e3 xem x\u00e9t \u0111\u1ed9 ch\u00ednh x\u00e1c c\u1ee7a k\u1ebft qu\u1ea3 thu \u0111\u01b0\u1ee3c b\u1eb1ng c\u00e1ch t\u1ef1 l\u1ea5y m\u1eabu t\u1ea1i nh\u00e0, t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi vi\u1ec7c t\u1ef1 l\u1ea5y m\u1eabu t\u1ea1i nh\u00e0, t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi thu \u0111\u01b0\u1ee3c khi l\u1ea5y m\u1eabu \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi b\u00e1c s\u0129 ho\u1eb7c chuy\u00ean gia ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe [7].\u00a0T\u1ef1 l\u1ea5y m\u1eabu c\u00f3 th\u1ec3 gi\u00fap t\u0103ng c\u01b0\u1eddng s\u1ef1 h\u1ea5p thu c\u1ee7a s\u00e0ng l\u1ecdc. S\u00e0ng l\u1ecdc ban \u0111\u1ea7u v\u1edbi x\u00e9t nghi\u1ec7m DNA HPV l\u00e0 m\u1ed9t chi\u1ebfn l\u01b0\u1ee3c hi\u1ec7u qu\u1ea3 v\u1ec1 chi ph\u00ed cho Th\u00e1i Lan, gi\u00fap ph\u00e1t hi\u1ec7n s\u1edbm ung th\u01b0 c\u1ed5 t\u1eed cung v\u00e0 ung th\u01b0 \u1edf nhi\u1ec1u ph\u1ee5 n\u1eef h\u01a1n v\u00e0 cu\u1ed1i c\u00f9ng l\u00e0 tr\u00e1nh nh\u1eefng tr\u01b0\u1eddng h\u1ee3p t\u1eed vong kh\u00f4ng c\u1ea7n thi\u1ebft do b\u1ec7nh n\u00e0y. T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/em><\/p>\n

[1]<\/a>\u00a0Human Papillomavirus and Related Diseases Report. HPV Information Centre<\/p>\n

[2]<\/a>\u00a0Pap Smear vs. HPV Screening Tests for Cervical Cancer<\/p>\n

[3]<\/a> HPV\/Genital Warts<\/p>\n

[4]<\/a>\u00a0FDA approves first human papillomavirus test for primary cervical cancer screening; US Food and Drug Administration<\/p>\n

[5]<\/a>\u00a0Sankaranarayanan, R., et al.,\u00a02009. HPV Screening for Cervical Cancer in Rural India.\u00a0New England Journal of Medicine<\/i>, 361(3), pp.304-306.<\/p>\n

[6]<\/a>\u00a0Termrungruanglert, W., et al., 2017.\u00a0Cost-effectiveness analysis study of HPV testing as a primary cervical cancer screening in Thailand.\u00a0Gynecologic oncology reports<\/i>,\u00a022, pp.58\u201363.<\/p>\n

[7]<\/a>\u00a0Nilyanimit, P., et al., 2014.\u00a0Comparison of Detection Sensitivity for Human Papillomavirus between Self-collected Vaginal Swabs and Physician-collected Cervical Swabs by Electrochemical DNA Chip.\u00a0Asian Pacific Journal of Cancer Prevention,\u00a015(24), pp.10809-10812.<\/p>\n","protected":false},"excerpt":{"rendered":"

H\u01a1n 5.000 ph\u1ee5 n\u1eef \u1edf Th\u00e1i Lan t\u1eed vong m\u1ed7i n\u0103m do ung th\u01b0 c\u1ed5 t\u1eed cung. 70% c\u00e1c lo\u1ea1i ung th\u01b0 n\u00e0y do hai ch\u1ee7ng HPV (human papillomavirus) g\u00e2y ra, c\u1ea3 hai \u0111\u1ec1u c\u00f3 th\u1ec3 ph\u00f2ng ng\u1eeba \u0111\u01b0\u1ee3c b\u1eb1ng c\u00e1ch ti\u00eam v\u1eafc-xin.<\/p>\n","protected":false},"author":1,"featured_media":84216,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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