{"id":147397,"date":"2022-01-28T03:12:12","date_gmt":"2022-01-28T03:12:12","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/cham-dut-hcv-o-sindh-thong-tin-chuyen-sau-tu-giao-su-muhammad-sadik-memon-va-tien-si-zaigham-abbas\/"},"modified":"2026-02-23T07:38:10","modified_gmt":"2026-02-23T07:38:10","slug":"hcv-elimination-in-sindh-insights-from-prof-muhammad-sadik-memon-and-dr-zaigham-abbas","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/vi\/disease-area\/infectious-diseases\/hcv-elimination-in-sindh-insights-from-prof-muhammad-sadik-memon-and-dr-zaigham-abbas\/","title":{"rendered":"Ch\u1ea5m d\u1ee9t HCV \u1edf Sindh: th\u00f4ng tin chuy\u00ean s\u00e2u t\u1eeb Gi\u00e1o s\u01b0 Muhammad Sadik Memon v\u00e0 Ti\u1ebfn s\u0129 Zaigham Abbas"},"content":{"rendered":"

B\u00e0i vi\u1ebft n\u00e0y l\u00e0 m\u1ed9t ph\u1ea7n c\u1ee7a lo\u1ea1t b\u00e0i v\u1ec1 c\u00f4ng cu\u1ed9c ch\u1ea5m d\u1ee9t vi-r\u00fat vi\u00eam gan C (HCV) t\u1ea1i Pakistan v\u00e0 c\u00e1c qu\u1ed1c gia c\u00f3 nguy c\u01a1 cao kh\u00e1c tr\u00ean th\u1ebf gi\u1edbi. C\u00e1c b\u00e0i vi\u1ebft kh\u00e1c trong lo\u1ea1t b\u00e0i n\u00e0y \u0111\u1ec1 c\u1eadp \u0111\u1ebfn c\u00e1c t\u1ec9nh Punjab v\u00e0 KPK c\u1ee7a Pakistan. Vui l\u00f2ng cu\u1ed9n xu\u1ed1ng cu\u1ed1i b\u00e0i vi\u1ebft \u0111\u1ec3 xem danh s\u00e1ch \u0111\u1ea7y \u0111\u1ee7.<\/em><\/p>\n

HBV v\u00e0 HCV l\u00e0 m\u1ed1i \u0111e d\u1ecda l\u1edbn \u0111\u1ed1i v\u1edbi y t\u1ebf c\u00f4ng c\u1ed9ng \u1edf Pakistan, \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn g\u1ea7n 15 tri\u1ec7u ng\u01b0\u1eddi tr\u00ean kh\u1eafp c\u1ea3 n\u01b0\u1edbc. T\u1ec9nh Sindh l\u00e0 m\u1ed9t trong nh\u1eefng n\u01a1i c\u00f3 t\u1ef7 l\u1ec7 nhi\u1ec5m HCV cao nh\u1ea5t th\u1ebf gi\u1edbi v\u00e0 g\u00e1nh ch\u1ecbu g\u00e1nh n\u1eb7ng b\u1ec7nh cao th\u1ee9 hai v\u1ec1 c\u1ea3 HBV v\u00e0 HCV trong s\u1ed1 t\u1ea5t c\u1ea3 c\u00e1c t\u1ec9nh \u1edf Pakistan [1].<\/p>\n

N\u1eb1m \u1edf g\u00f3c \u0111\u00f4ng nam c\u1ee7a \u0111\u1ea5t n\u01b0\u1edbc, t\u1ec9nh Sindh ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi nhi\u1ec1u th\u00e1ch th\u1ee9c trong vi\u1ec7c ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh li\u00ean quan \u0111\u1ebfn HCV cho 48 tri\u1ec7u c\u01b0 d\u00e2n c\u1ee7a m\u00ecnh. Gi\u1ed1ng nh\u01b0 h\u1ea7u h\u1ebft c\u00e1c khu v\u1ef1c kh\u00e1c trong c\u1ea3 n\u01b0\u1edbc, tr\u00ecnh \u0111\u1ed9 hi\u1ec3u bi\u1ebft th\u1ea5p v\u1ec1 s\u1ee9c kh\u1ecfe c\u1ee7a ng\u01b0\u1eddi d\u00e2n d\u1eabn \u0111\u1ebfn nh\u1eefng h\u00e0nh vi kh\u00f4ng l\u00e0nh m\u1ea1nh, ch\u1eb3ng h\u1ea1n nh\u01b0\u00a0t\u00e1i s\u1eed d\u1ee5ng kim ti\u00eam \u0111\u1ec3 ti\u00eam thu\u1ed1c v\u00e0 kh\u1eed tr\u00f9ng k\u00e9m cho c\u00e1c thi\u1ebft b\u1ecb y t\u1ebf. T\u1ec9nh c\u00f3 d\u00e2n s\u1ed1 l\u1edbn th\u1ee9 hai sau Punjab n\u00e0y c\u0169ng ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi nhi\u1ec1u h\u1ea1n ch\u1ebf v\u1ec1 c\u01a1 s\u1edf h\u1ea1 t\u1ea7ng, l\u1ef1c l\u01b0\u1ee3ng lao \u0111\u1ed9ng v\u00e0 t\u00e0i ch\u00ednh gi\u1ed1ng nh\u01b0 c\u00e1c v\u00f9ng l\u00e3nh th\u1ed5 l\u00e2n c\u1eadn. \u0110i\u1ec1u n\u00e0y \u0111\u1eb7c bi\u1ec7t \u0111\u00fang \u1edf c\u00e1c v\u00f9ng n\u00f4ng th\u00f4n c\u1ee7a Sindh, n\u01a1i sinh s\u1ed1ng c\u1ee7a g\u1ea7n m\u1ed9t n\u1eeda d\u00e2n s\u1ed1 c\u1ee7a t\u1ec9nh.<\/p>\n

\u0110\u1ec3 t\u00ecm hi\u1ec3u th\u00eam v\u1ec1 nh\u1eefng th\u00e1ch th\u1ee9c n\u00e0y v\u00e0 c\u01a1 h\u1ed9i gi\u1ea3i quy\u1ebft ch\u00fang, Lab Insights \u0111\u00e3 trao \u0111\u1ed5i v\u1edbi hai nh\u00e2n v\u1eadt n\u1ed5i b\u1eadt trong cu\u1ed9c chi\u1ebfn ch\u1ed1ng l\u1ea1i HCV t\u1ea1i t\u1ec9nh Sindh: Gi\u00e1o s\u01b0 Muhammad Sadik Memon, B\u00e1c s\u0129 t\u01b0 v\u1ea5n ki\u00eam B\u00e1c s\u0129 chuy\u00ean khoa ti\u00eau h\u00f3a t\u1ea1i Asian Institute of Medical Sciences \u1edf Hyderabad; v\u00e0 Ti\u1ebfn s\u0129 Zaigham Abbas, Tr\u01b0\u1edfng khoa Ti\u00eau h\u00f3a t\u1ea1i Ziauddin University Hospital \u1edf Karachi.<\/p>\n

M\u1edf r\u1ed9ng kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn th\u00f4ng qua ch\u00ednh s\u00e1ch<\/h2>\n

C\u00f9ng v\u1edbi ch\u01b0\u01a1ng tr\u00ecnh c\u1ea5p qu\u1ed1c gia c\u1ee7a Th\u1ee7 t\u01b0\u1edbng h\u01b0\u1edbng t\u1edbi m\u1ee5c ti\u00eau c\u1ee7a WHO l\u00e0 ch\u1ea5m d\u1ee9t HCV t\u1ea1i Pakistan tr\u01b0\u1edbc n\u0103m 2030, t\u1ec9nh Sindh \u0111\u00e3 tri\u1ec3n khai Ch\u01b0\u01a1ng tr\u00ecnh Ph\u00f2ng ng\u1eeba v\u00e0 Ki\u1ec3m so\u00e1t Vi\u00eam gan, h\u01b0\u1edbng t\u1edbi m\u1ee5c ti\u00eau m\u1ed9t Sindh kh\u00f4ng c\u00f2n b\u1ec7nh vi\u00eam gan.<\/p>\n

Trong nh\u1eefng n\u1ed7 l\u1ef1c \u0111\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c m\u1ee5c ti\u00eau n\u00e0y, 48 \u0111i\u1ec3m gi\u00e1m s\u00e1t \u0111\u00e3 \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp tr\u00ean to\u00e0n t\u1ec9nh. M\u1ed7i \u0111i\u1ec3m \u0111\u1ec1u c\u00f3 m\u1ed9t nh\u00f3m bao g\u1ed3m nh\u00e2n vi\u00ean y t\u1ebf, y t\u00e1, ng\u01b0\u1eddi x\u1eed l\u00fd d\u1eef li\u1ec7u, k\u1ef9 thu\u1eadt vi\u00ean ph\u00f2ng x\u00e9t nghi\u1ec7m v\u00e0 nh\u00e2n vi\u00ean h\u1ed7 tr\u1ee3. C\u00e1c \u0111i\u1ec3m n\u00e0y cung c\u1ea5p nhi\u1ec1u ngu\u1ed3n l\u1ef1c mi\u1ec5n ph\u00ed, bao g\u1ed3m x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc HCV, ch\u1ee7ng ng\u1eeba HBV v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u1ea3 HCV v\u00e0 HBV. Sindh c\u00f3 c\u00e1c ph\u00f2ng x\u00e9t nghi\u1ec7m t\u1eadp trung \u0111\u1ec3 x\u00e9t nghi\u1ec7m PCR v\u00e0 c\u00e1c l\u1ef1a ch\u1ecdn h\u1eadu c\u1ea7n \u0111\u1ea7y \u0111\u1ee7 \u0111\u1ec3 v\u1eadn chuy\u1ec3n m\u1eabu t\u1eeb c\u00e1c trung t\u00e2m thu th\u1eadp \u1edf v\u00f9ng n\u00f4ng th\u00f4n; tuy nhi\u00ean, c\u1ea7n nhi\u1ec1u k\u1ef9 thu\u1eadt vi\u00ean h\u01a1n \u0111\u1ec3 th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m PCR.<\/p>\n

M\u1eb7c d\u00f9 c\u00f3 c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh c\u1ea5p qu\u1ed1c gia v\u00e0 c\u1ea5p khu v\u1ef1c m\u1ea1nh m\u1ebd nh\u1eb1m ch\u1ea5m d\u1ee9t HCV nh\u01b0ng c\u00e1c chuy\u00ean gia \u0111\u1ec1u \u0111\u1ed3ng \u00fd r\u1eb1ng c\u1ea7n ph\u1ea3i ti\u1ebfp c\u1eadn nhi\u1ec1u h\u01a1n \u1edf c\u00e1c v\u00f9ng n\u00f4ng th\u00f4n. \u201cCh\u00fang ta c\u1ea7n x\u00e9t nghi\u1ec7m to\u00e0n b\u1ed9 c\u1ed9ng \u0111\u1ed3ng c\u00f9ng m\u1ed9t l\u00fac v\u00e0 sau \u0111\u00f3 ti\u00eam v\u1eafc-xin cho h\u1ecd\u201d, Gi\u00e1o s\u01b0 Memon ph\u00e1t bi\u1ec3u. Tuy nhi\u00ean, v\u1eabn c\u00f2n t\u1ed3n t\u1ea1i nhi\u1ec1u kho\u1ea3ng tr\u1ed1ng, \u0111\u1eb7c bi\u1ec7t l\u00e0 trong n\u1ed7 l\u1ef1c s\u00e0ng l\u1ecdc HCV. Ti\u1ebfn s\u0129 Abbas cho bi\u1ebft: \u201cCh\u00fang ta th\u1ef1c s\u1ef1 kh\u00f4ng th\u1ec3 t\u00ecm th\u1ea5y h\u00e0ng tri\u1ec7u ng\u01b0\u1eddi c\u00f2n thi\u1ebfu \u2013 nh\u1eefng ng\u01b0\u1eddi l\u00e0 ngu\u1ed3n l\u00e2y truy\u1ec1n b\u1ec7nh\u201d.<\/p>\n

M\u1ed9t ph\u1ea7n c\u1ee7a v\u1ea5n \u0111\u1ec1 l\u00e0 c\u00e1c c\u01a1 quan y t\u1ebf c\u00f3 nh\u1eefng \u01b0u ti\u00ean kh\u00e1c, ch\u1eb3ng h\u1ea1n nh\u01b0 ch\u1ed1ng l\u1ea1i c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m kh\u00e1c nh\u01b0 COVID-19, b\u1ea1i li\u1ec7t v\u00e0 s\u1ed1t r\u00e9t. Ti\u1ebfn s\u0129 Abbas k\u00eau g\u1ecdi: \u201cCh\u00fang ta c\u1ea7n ti\u1ebfp t\u1ee5c g\u00e2y s\u1ee9c \u00e9p v\u1edbi ch\u00ednh ph\u1ee7 \u0111\u1ec3 c\u00e1c ch\u00ednh tr\u1ecb gia nh\u1eadn th\u1ee9c \u0111\u01b0\u1ee3c m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a t\u00ecnh h\u00ecnh.\u201d \u201cCh\u00fang ta kh\u00f4ng n\u00ean n\u1ea3n l\u00f2ng n\u1ebfu ban \u0111\u1ea7u kh\u00f4ng nh\u1eadn \u0111\u01b0\u1ee3c ph\u1ea3n \u1ee9ng ph\u00f9 h\u1ee3p.\u201d<\/p>\n

Quy tr\u00ecnh s\u00e0ng l\u1ecdc v\u00e0 \u0111i\u1ec1u tr\u1ecb HCV t\u1ea1i Sindh<\/h2>\n

Gi\u00e1o s\u01b0 Memon gi\u1ea3i th\u00edch r\u1eb1ng khi b\u1ec7nh nh\u00e2n c\u00f3 k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m d\u01b0\u01a1ng t\u00ednh v\u1edbi HCV, tr\u01b0\u1edbc ti\u00ean h\u1ecd s\u1ebd \u0111\u01b0\u1ee3c khuy\u1ebfn kh\u00edch ti\u00eam v\u1eafc-xin ph\u00f2ng ng\u1eeba HBV. Sau \u0111\u00f3, x\u00e9t nghi\u1ec7m PCR \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n th\u00eam \u0111\u1ec3 x\u00e1c nh\u1eadn s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a HCV v\u00e0 x\u00e9t nghi\u1ec7m que th\u1eed d\u00f2ng ch\u1ea3y b\u00ean (LFD) v\u00e0 si\u00eau \u00e2m \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng \u0111\u1ec3 lo\u1ea1i tr\u1eeb b\u1ec7nh x\u01a1 gan. N\u1ebfu b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n m\u1eafc b\u1ec7nh x\u01a1 gan, h\u1ecd s\u1ebd \u0111\u01b0\u1ee3c theo d\u00f5i qua \u0111i\u1ec7n tho\u1ea1i s\u00e1u th\u00e1ng m\u1ed9t l\u1ea7n v\u00e0 \u0111\u01b0\u1ee3c khuy\u1ebfn kh\u00edch th\u1ef1c hi\u1ec7n \u0111\u00e1nh gi\u00e1 b\u1eb1ng si\u00eau \u00e2m v\u00e0 n\u1ed9i soi khi c\u1ea7n thi\u1ebft. Gi\u00e1o s\u01b0 Memon c\u0169ng l\u01b0u \u00fd r\u1eb1ng y t\u00e1 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u00e0o t\u1ea1o \u0111\u1ec3 gi\u00fap qu\u1ea3n l\u00fd nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc HCV kh\u00f4ng b\u1ecb x\u01a1 gan, v\u00e0 \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 gi\u1ea3m b\u1edbt g\u00e1nh n\u1eb7ng cho c\u00e1c b\u00e1c s\u0129.<\/p>\n

X\u00e9t nghi\u1ec7m PCR \u1edf Pakistan c\u00f3 th\u1ec3 t\u1ed1n k\u00e9m v\u00e0 nhi\u1ec1u b\u1ec7nh nh\u00e2n l\u00e0m x\u00e9t nghi\u1ec7m n\u00e0y ph\u1ea3i th\u1ef1c hi\u1ec7n \u1edf n\u01a1i ri\u00eang t\u01b0. Tuy nhi\u00ean, vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c kh\u00e1ng vi-r\u00fat t\u00e1c d\u1ee5ng tr\u1ef1c ti\u1ebfp (DAA) \u0111\u01b0\u1ee3c ch\u00ednh ph\u1ee7 cung c\u1ea5p mi\u1ec5n ph\u00ed. Ngo\u00e0i ra, b\u1ec7nh vi\u1ec7n c\u1ee7a Gi\u00e1o s\u01b0 Memon c\u00f2n c\u00f3 th\u1ec3 cung c\u1ea5p ba th\u00e1ng \u0111i\u1ec1u tr\u1ecb mi\u1ec5n ph\u00ed b\u1eb1ng DAA. Sau khi \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n, \u00f4ng gi\u1ea3i th\u00edch r\u1eb1ng h\u1ecd s\u1ebd \u0111\u01b0\u1ee3c theo d\u00f5i b\u1eb1ng c\u00e1c x\u00e9t nghi\u1ec7m PCR v\u00e0 LFD th\u00eam sau s\u00e1u th\u00e1ng ho\u1eb7c \u0111\u01b0\u1ee3c gi\u1edbi thi\u1ec7u \u0111\u1ebfn b\u00e1c s\u0129 \u0111\u1ecba ph\u01b0\u01a1ng \u0111\u1ec3 ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb v\u00e0 theo d\u00f5i.<\/p>\n

\u0110\u1ec3 t\u0103ng c\u01b0\u1eddng c\u00e1c d\u1ecbch v\u1ee5 s\u00e0ng l\u1ecdc v\u00e0 \u0111i\u1ec1u tr\u1ecb HCV t\u1ea1i Sindh, Gi\u00e1o s\u01b0 Memon l\u01b0u \u00fd r\u1eb1ng vi\u1ec7c n\u00e2ng cao nh\u1eadn th\u1ee9c c\u1ee7a c\u1ea3 nh\u00e2n vi\u00ean ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe v\u00e0 ng\u01b0\u1eddi d\u00e2n l\u00e0 r\u1ea5t quan tr\u1ecdng. Song song v\u1edbi \u0111\u00f3, \u0111i\u1ec1u quan tr\u1ecdng l\u00e0 ph\u1ea3i g\u00e2y s\u1ee9c \u00e9p l\u00ean ch\u00ednh ph\u1ee7 v\u00e0 n\u00eau b\u1eadt m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a t\u00ecnh h\u00ecnh. S\u1ef1 h\u1ed7 tr\u1ee3 c\u1ee7a ch\u00ednh ph\u1ee7 s\u1ebd l\u00e0 ch\u00eca kh\u00f3a \u0111\u1ec3 t\u0103ng c\u01b0\u1eddng n\u0103ng l\u1ef1c ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe, ti\u1ebfn h\u00e0nh s\u00e0ng l\u1ecdc h\u00e0ng lo\u1ea1t v\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 \u0111i\u1ec1u tr\u1ecb v\u00e0 ti\u00eam ch\u1ee7ng HBV.<\/p>\n

\u0110\u1ec3 t\u00ecm hi\u1ec3u th\u00eam v\u1ec1 g\u00e1nh n\u1eb7ng ng\u00e0y c\u00e0ng gia t\u0103ng v\u1ec1 HCV \u1edf Pakistan v\u00e0 Ch\u00e2u \u00c1 \u2013 Th\u00e1i B\u00ecnh D\u01b0\u01a1ng, h\u00e3y xem c\u00e1c nghi\u00ean c\u1ee9u \u0111i\u1ec3n h\u00ecnh kh\u00e1c tr\u00ean Lab Insights:<\/em><\/p>\n