{"id":145310,"date":"2021-08-06T06:05:16","date_gmt":"2021-08-06T06:05:16","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e8%84%91%e8%84%8a%e6%b6%b2%e7%94%9f%e7%89%a9%e6%a0%87%e5%bf%97%e7%89%a9%e5%8f%8a%e5%85%b6%e5%9c%a8%e9%98%bf%e5%b0%94%e8%8c%a8%e6%b5%b7%e9%bb%98%e7%97%85%e7%ae%a1%e7%90%86%e4%b8%ad%e7%9a%84%e4%bd%9c\/"},"modified":"2026-01-21T12:04:21","modified_gmt":"2026-01-21T12:04:21","slug":"csf-biomarkers-and-their-role-in-alzheimers-disease-management","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/zhcn\/operations\/immunoassay\/csf-biomarkers-and-their-role-in-alzheimers-disease-management\/","title":{"rendered":"\u8111\u810a\u6db2\u751f\u7269\u6807\u5fd7\u7269\u53ca\u5176\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7ba1\u7406\u4e2d\u7684\u4f5c\u7528"},"content":{"rendered":"

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\u4ec0\u4e48\u662f\u8111\u810a\u6db2\u751f\u7269\u6807\u5fd7\u7269\uff1f<\/h3>\n

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\u9274\u4e8e\u591a\u9879\u4e34\u5e8a\u6307\u5357\u7684\u4fee\u8ba2\u8c03\u6574\uff0c\u4f8b\u5982\u7f8e\u56fd\u56fd\u5bb6\u8001\u9f84\u5316\u7814\u7a76\u6240\u548c\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u534f\u4f1a\uff08National Institute of Aging and Alzheimer’s Association\u00a0\uff0c\u7b80\u79f0 NIA-AA\u00a0\uff09\u8bc4\u4f30\u8ba4\u5b9a\uff0c\u65e0\u8bba\u75c7\u72b6\u662f\u5426\u5b58\u5728\u4ee5\u53ca\u4e25\u91cd\u7a0b\u5ea6\u5982\u4f55\uff0c\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u8bca\u65ad\u5982\u4eca\u5747\u53ef\u57fa\u4e8e\u751f\u7269\u5b66\u4f9d\u636e[4]\uff0c\u518d\u52a0\u4e0a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u534f\u4f1a (Alzheimer\u2019s Association) \u5f00\u5c55\u7684\u4e00\u9879\u5916\u90e8\u8d28\u91cf\u63a7\u5236\u8ba1\u5212[5]\uff0c\u5f53\u4e0b\u5728\u4e34\u5e8a\u73af\u5883\u4e2d\u66f4\u5e7f\u6cdb\u5730\u8fd0\u7528\u8111\u810a\u6db2\u751f\u7269\u6807\u5fd7\u7269\u6216\u8bb8\u5df2\u5177\u5907\u53ef\u884c\u6761\u4ef6\u3002\u82e5\u83b7\u5f97\u6279\u51c6\uff0c\u501f\u52a9\u81ea\u52a8\u5316\u6280\u672f\u540c\u6837\u80fd\u591f\u589e\u52a0\u8111\u810a\u6db2\u751f\u7269\u6807\u5fd7\u7269\u7684\u4f7f\u7528\u9891\u6b21\uff0c\u8fdb\u800c\u51cf\u5c11\u4eba\u5de5\u64cd\u4f5c\u5e26\u6765\u7684\u8bef\u5dee\u3002<\/p>\n

\u53ca\u65f6\u8bca\u65ad\u7684\u76ca\u5904<\/h3>\n

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\u4f5c\u4e3a\u4f34\u968f\u8bca\u65ad\u7684\u6f5c\u5728\u5e94\u7528<\/h3>\n

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\u53c2\u8003\u8d44\u6599<\/em>\uff1a<\/p>\n

[1]<\/a> Dementia in the Asia Pacific Region 2014 Report, Alzheimer’s Disease International<\/p>\n

[2]<\/a>\u00a0Buchhave, P.et al. (2012)\u00a0Cerebrospinal Fluid Levels of \u03b2-Amyloid 1-42, but Not of Tau, Are Fully Changed Already 5 to 10 Years Before the Onset of Alzheimer Dementia.\u00a0Archives of General Psychiatry<\/i>, 69(1), pp98.<\/p>\n

[3]<\/a>\u00a0Olsson, B., et al. (2016) CSF and blood biomarkers for the diagnosis of Alzheimer\u2019s disease: a systematic review and meta-analysis.The Lancet Neurology<\/em>, 15, pp673-684.<\/p>\n

[4]<\/a>\u00a0Alzheimer’s Disease Diagnostic Guidelines, Dementia Resources for Health Professionals, National Institute of Health<\/p>\n

[5]<\/a>\u00a0The Alzheimer’s Association QC program for CSF and blood biomarkers<\/p>\n

[6]<\/a> Dubois, B.et al. (2016) Timely diagnosis for Alzheimer’s Disease: A Literature Review on Benefits and Challenges.Journal of Alzheimer’s Disease<\/em>, 49, pp617-631.<\/p>\n

[7]<\/a>\u00a0Lleo, A.et al. (2014) Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases.Nature Reviews Neurology<\/em>, 11, pp41-55.<\/p>\n

[8]<\/a>\u00a0Horgan, D.et al. (2020) Biomarker Testing: Piercing the Fog of Alzheimer’s and Related Dementia.\u751f\u7269\u533b\u5b66\u4e2d\u5fc3<\/p>\n","protected":false},"excerpt":{"rendered":"

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