{"id":145589,"date":"2023-06-01T01:53:26","date_gmt":"2023-06-01T01:53:26","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e6%96%b0%e5%9e%8b-hbv-%e7%94%9f%e7%89%a9%e6%a0%87%e5%bf%97%e7%89%a9%e5%8a%a9%e5%8a%9b%e5%87%8f%e5%b0%91%e7%97%85%e6%af%92\/"},"modified":"2026-01-21T12:20:36","modified_gmt":"2026-01-21T12:20:36","slug":"new-hbv-biomarkers-support-virus-reduction-efforts","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/zhcn\/operations\/immunoassay\/new-hbv-biomarkers-support-virus-reduction-efforts\/","title":{"rendered":"\u65b0\u578b HBV \u751f\u7269\u6807\u5fd7\u7269\u52a9\u529b\u51cf\u5c11\u75c5\u6bd2"},"content":{"rendered":"

\u5728\u5168\u7403\u4e3a\u964d\u4f4e\u4e59\u578b\u809d\u708e (HBV) \u6b7b\u4ea1\u7387\u7684\u536b\u751f\u884c\u52a8\u4e0d\u65ad\u5347\u7ea7\u4e4b\u9645\uff0c\u6765\u81ea\u4e16\u754c\u5404\u5730\u7684\u5b9e\u9a8c\u5ba4\u548c\u533b\u7597\u9886\u57df\u7684\u9886\u5bfc\u8005\u53ca\u4e13\u5bb6\u6b63\u5f00\u53d1\u548c\u5e94\u7528\u65b0\u578b\u751f\u7269\u6807\u5fd7\u7269\uff0c\u4ee5\u6307\u5bfc\u8bca\u7597\u7b56\u7565\u3002\u5728 Roche Diagnostics \u6700\u8fd1\u4e3e\u529e\u7684\u4e00\u573a\u7f51\u7edc\u7814\u8ba8\u4f1a\u4e0a\uff0c\u6765\u81ea\u6fb3\u5927\u5229\u4e9a\u7684\u4e24\u540d\u75c5\u6bd2\u5b66\u4e13\u5bb6\u8ba8\u8bba\u4e86 HBV \u8bca\u65ad\u7684\u6700\u65b0\u8fdb\u5c55\u53ca\u5176\u5728\u6fb3\u5927\u5229\u4e9a\u7684\u6f5c\u5728\u5e94\u7528\u3002<\/p>\n

\u4ee5\u4e0b\u662f\u672c\u6b21\u7f51\u7edc\u7814\u8ba8\u4f1a\u7684\u90e8\u5206\u5173\u952e\u8981\u70b9\u3002\u4e3b\u8bb2\u5609\u5bbe\u5305\u62ec\uff1a\u58a8\u5c14\u672c\u5927\u5b66\u5723\u6587\u68ee\u7279\u533b\u9662\u80c3\u80a0\u75c5\u5b66\u7cfb\u4e3b\u4efb Alex Thompson \u6559\u6388\uff0c\u4ee5\u53ca\u6fb3\u5927\u5229\u4e9a\u6089\u5c3c\u5927\u5b66\u4e0e The Westmead Institute for Medical Research \u7684 Storr Liver Centre \u7684 Mark Douglas \u526f\u6559\u6388\u3002<\/p>\n

\u964d\u4f4e HBV \u7684\u91cd\u8981\u6027<\/h2>\n

\u5168\u7403\u6709 20 \u4ebf\u4eba\u5728\u5176\u4e00\u751f\u4e2d\u7684\u67d0\u4e2a\u9636\u6bb5\u66fe\u611f\u67d3\u8fc7 HBV\uff0c\u5176\u4e2d\u7ea6 3 \u4ebf\u4eba\u4e3a\u6162\u6027\u611f\u67d3\u8005\uff0cHBV \u6784\u6210\u4e86\u5de8\u5927\u7684\u5168\u7403\u5065\u5eb7\u6311\u6218\u3002\u5982\u679c\u4e0d\u4e88\u6cbb\u7597\uff0c\u591a\u8fbe 40% \u7684\u60a3\u8005\u53ef\u80fd\u6b7b\u4e8e\u75c5\u6bd2\u5bfc\u81f4\u7684\u809d\u786c\u5316\u6216\u809d\u764c\u3002<\/p>\n

\u8fd9\u4e5f\u662f\u5404\u516c\u5171\u536b\u751f\u673a\u6784\u5c06 HBV \u4f5c\u4e3a\u91cd\u70b9\u5bf9\u8c61\uff0c\u5f00\u5c55\u5927\u89c4\u6a21\u884c\u52a8\u4ee5\u51cf\u5c11\u751a\u81f3\u6d88\u9664\u8be5\u75c5\u6bd2\u7684\u539f\u56e0\u30022016 \u5e74\uff0c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u5ba3\u5e03\u4e00\u9879\u8ba1\u5212<\/a>\uff0c\u529b\u4e89\u5230 2030 \u5e74\u5c06 HBV \u611f\u67d3\u51cf\u5c11 90%\uff0c\u76f8\u5173\u7684\u6b7b\u4ea1\u51cf\u5c11 65%\u3002 \u8be5\u8ba1\u5212\u7684\u5173\u952e\u5728\u4e8e\u5728\u5206\u5a29\u524d\u6216\u5206\u5a29\u671f\u95f4\u91cd\u70b9\u963b\u65ad\u6bcd\u5a74\u4f20\u64ad\uff0c\u5e76\u901a\u8fc7\u52a0\u5f3a\u75ab\u82d7\u63a5\u79cd\u3001\u68c0\u6d4b\u548c\u6cbb\u7597\u6765\u51cf\u8f7b\u75be\u75c5\u8d1f\u62c5\u3002<\/p>\n

\u5173\u6ce8\u598a\u5a20\u6bcd\u4eb2\u5411\u5a74\u513f\u7684\u5782\u76f4\u4f20\u64ad\uff0c\u5bf9\u5e94\u5bf9\u6162\u6027 HBV \u611f\u67d3\u8fd9\u4e00\u6311\u6218\u5c24\u4e3a\u91cd\u8981\u3002\u6210\u4eba\u611f\u67d3 HBV \u540e\uff0c\u53d1\u5c55\u4e3a\u6162\u6027\u611f\u67d3\u7684\u6982\u7387\u4ec5\u7ea6\u4e3a 5%\u3002\u4f46\u5728\u51fa\u751f\u524d\u6216\u51fa\u751f\u65f6\u7531\u6bcd\u4eb2\u611f\u67d3 HBV \u7684\u5a74\u513f\uff0c\u5176\u53d1\u5c55\u4e3a\u6162\u6027\u611f\u67d3\u7684\u98ce\u9669\u9ad8\u8fbe 90%\u3002<\/p>\n

\u6162\u6027HBV\u75c5\u4f8b\u9700\u8981\u6301\u7eed\u6cbb\u7597\u548c\u6301\u7eed\u76d1\u6d4b\uff0c\u56e0\u6b64\u6700\u5177\u6311\u6218\u6027\u3002<\/p>\n

\u6fb3\u5927\u5229\u4e9a\u7684 HBV \u751f\u7269\u6807\u5fd7\u7269\u5f00\u53d1<\/h2>\n

\u5728\u6fb3\u5927\u5229\u4e9a\uff0c\u4e00\u9879\u56fd\u5bb6\u6218\u7565\u65e8\u5728\u52a0\u5f3a\u513f\u7ae5\u75ab\u82d7\u63a5\u79cd\uff0c\u6269\u5927\u8bca\u65ad\u4ee5\u53d1\u73b0\u66f4\u591a\u6162\u6027\u75c5\u4f8b\uff0c\u5e76\u589e\u52a0\u6297\u75c5\u6bd2\u836f\u7269\u548c\u5176\u4ed6\u6cbb\u7597\u836f\u7269\u7684\u4f9b\u5e94\u3002Thompson \u6559\u6388\u548c Douglas \u6559\u6388\u6b63\u5728\u7814\u7a76\u591a\u79cd\u6297\u539f\u53ca\u5176\u4ed6\u751f\u7269\u6807\u5fd7\u7269\uff0c\u4ee5\u8bc4\u4f30\u5176\u5728\u60a3\u8005\u8bca\u65ad\u53ca\u6cbb\u7597\u671f\u95f4\u76d1\u6d4b\u4e2d\u7684\u5e94\u7528\u4ef7\u503c\uff0c\u4e3a\u8fd9\u4e00\u9632\u63a7\u4e8b\u4e1a\u4f5c\u51fa\u8d21\u732e\u3002<\/p>\n

\u81ea HBV \u611f\u67d3\u5f00\u59cb\uff0c\u8840\u6db2\u4e2d\u5373\u53ef\u68c0\u6d4b\u5230\u8868\u9762\u6297\u539f\uff0c\u800c\u5728\u6162\u6027\u60a3\u8005\u4e2d\uff0c\u5f53\u8868\u9762\u6297\u539f\u8f6c\u4e3a\u4e0d\u53ef\u68c0\u6d4b\u65f6\uff0c\u4e00\u822c\u8ba4\u4e3a\u8fbe\u5230\u4e86\u529f\u80fd\u6027\u6cbb\u6108\u72b6\u6001\u3002HBV DNA \u68c0\u6d4b\u662f\u8bc4\u4f30\u60a3\u8005\u75c5\u6bd2\u8f7d\u91cf\u7684\u5e38\u7528\u65b9\u6cd5\uff0c\u4e5f\u662f\u5224\u65ad\u6cbb\u7597\u662f\u5426\u6709\u6548\u7684\u5173\u952e\u6307\u6807\uff0c\u800c HBeAg \u5219\u662f\u53cd\u6620\u673a\u4f53\u514d\u75ab\u63a7\u5236\u72b6\u6001\u7684\u91cd\u8981\u6807\u5fd7\u3002\u751f\u7269\u6807\u5fd7\u7269\u6d3b\u6027\u5728 HBV \u611f\u67d3\u8fc7\u7a0b\u4e2d\u53d1\u751f\u53d8\u5316\u3002<\/p>\n

Douglas \u6559\u6388\u8868\u793a\uff1a\u201c\u8981\u4e86\u89e3\u5982\u4f55\u76d1\u6d4b\u6240\u6709\u8fd9\u4e9b\u6807\u5fd7\u7269\uff0c\u5e76\u660e\u786e\u9700\u8981\u89c2\u5bdf\u54ea\u4e9b\u53d8\u5316\u6765\u51b3\u5b9a\u4f55\u65f6\u542f\u52a8\u6cbb\u7597\uff0c\u8fd9\u4e00\u70b9\u81f3\u5173\u91cd\u8981\u3002\u201d<\/p>\n

\u7ee7\u7eed\u5f00\u53d1\u5168\u65b0\u751f\u7269\u6807\u5fd7\u7269\u4e5f\u540c\u6837\u91cd\u8981\u3002Thompson \u6559\u6388\u8868\u793a\uff0c\u5168\u65b0\u6807\u5fd7\u7269\u6709\u671b\u4e3a HBV \u60a3\u8005\u5f00\u542f\u4e2a\u4f53\u5316\u533b\u7597\u7684\u65b0\u65f6\u4ee3\u3002\u4f8b\u5982\uff0c\u91c7\u7528 ELISA \u5bf9\u8868\u9762\u6297\u539f\u8fdb\u884c\u5b9a\u91cf\u68c0\u6d4b\uff0c\u800c\u975e\u4ec5\u7ed9\u51fa\u9634\u6027\u6216\u9633\u6027\u7ed3\u679c\uff0c\u53ef\u5728\u5224\u65ad\u6bcf\u4f4d\u60a3\u8005\u4f55\u65f6\u542f\u52a8\u6216\u505c\u6b62\u6cbb\u7597\u65f6\u53d1\u6325\u66f4\u5927\u7684\u53c2\u8003\u4ef7\u503c\u3002<\/p>\n

\u5168\u65b0\u6807\u5fd7\u7269\u8fd8\u53ef\u4ee5\u9884\u6d4b\u60a3\u8005\u662f\u5426\u53ef\u80fd\u8fbe\u5230\u529f\u80fd\u6027\u6cbb\u6108\u9636\u6bb5\uff0c\u4ee5\u53ca\u598a\u5a20\u60a3\u8005\u662f\u5426\u53ef\u80fd\u5c06\u75c5\u6bd2\u4f20\u67d3\u7ed9\u5a74\u513f\u3002\u5728\u5e72\u6270\u7d20\u6cbb\u7597\u7684\u65b0\u7814\u7a76\u4e2d\uff0c\u8868\u9762\u6297\u539f\u6c34\u5e73\u53ef\u4ee5\u9884\u6d4b\u54ea\u4e9b\u60a3\u8005\u5c06\u4ece\u7ee7\u7eed\u6cbb\u7597\u4e2d\u83b7\u76ca\uff0c\u54ea\u4e9b\u4e0d\u4f1a\u3002<\/p>\n

\u201c\u6211\u8ba4\u4e3a\u8868\u9762\u6297\u539f\u6c34\u5e73\u6307\u6807\u73b0\u5728\u5df2\u7ecf\u53ef\u4ee5\u8fdb\u5165\u4e34\u5e8a\u5e38\u89c4\u5e94\u7528\u4e86\u3002\u201dThompson \u6559\u6388\u8868\u793a\uff0c\u4ed6\u5efa\u8bae\u5bf9\u6240\u6709 HBV \u611f\u67d3\u8005\u5e38\u89c4\u68c0\u6d4b\u8fd9\u4e00\u751f\u7269\u6807\u5fd7\u7269\u3002\u8fd9\u79cd\u65b9\u6cd5\u5728\u672a\u6765\u4e5f\u6709\u671b\u5e2e\u52a9\u4e34\u5e8a\u5408\u7406\u7b5b\u9009\u6b63\u5728\u5f00\u53d1\u7684\u65b0\u578b\u6cbb\u7597\u65b9\u6848\uff0c\u4f8b\u5982\u76ee\u524d\u5904\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u7684\u6ce8\u5c04\u7528\u53cd\u4e49\u5be1\u6838\u82f7\u9178\u7b49\u3002\u201c\u6cbb\u7597\u4e59\u809d\u7684\u65b0\u65f6\u4ee3\u6b63\u5728\u5230\u6765\u201d\uff0c\u4ed6\u8865\u5145\u8bf4\u3002<\/p>\n

HBV RNA \u662f\u4e00\u79cd\u5177\u6709\u771f\u6b63\u524d\u666f\u7684\u5168\u65b0\u751f\u7269\u6807\u5fd7\u7269\uff0c\u5b83\u53ef\u80fd\u63d0\u4f9b\u6bd4 HBV DNA \u66f4\u6709\u7528\u7684\u8f6c\u5f55\u6d3b\u6027\u5feb\u7167\u3002\u4f8b\u5982\uff0c\u5728\u4e00\u9879 Hep B NA \u6cbb\u7597\u505c\u6b62\u7814\u7a76\u4e2d\uff0cHBV RNA \u5347\u9ad8\u88ab\u8bc1\u660e\u4f1a\u589e\u52a0\u809d\u708e\u53d1\u4f5c\u7684\u98ce\u9669\uff0c\u5e76\u4e0e HBsAg \u6d88\u5931\u5448\u8d1f\u76f8\u5173\u3002Thompson \u6559\u6388\u8fd8\u6307\u51fa\uff0cHBV RNA \u53ef\u80fd\u663e\u793a\u51fa\u4e34\u5e8a\u6548\u7528\uff0c\u53ef\u7528\u4e8e\u9884\u6d4b\u514d\u75ab\u529f\u80fd\u4f4e\u4e0b\u60a3\u8005\u7684 HBV \u518d\u6fc0\u6d3b\u3001HCC \u98ce\u9669\u6216\u5bf9\u65b0\u7597\u6cd5\u7684\u5e94\u7b54\u3002<\/p>\n

\u201c\u8840\u6e05 HBV RNA \u770b\u8d77\u6765\u5f88\u6709\u524d\u666f\uff0c\u9700\u8981\u8fdb\u4e00\u6b65\u7814\u7a76\u201d\uff0c\u4ed6\u8bf4\u3002\u201c\u6211\u671f\u5f85\u5728\u672a\u6765\u51e0\u5e74\u770b\u5230\u76f8\u5173\u7ed3\u679c\u548c\u6570\u636e\u3002\u201d<\/p>\n

\u5982\u9700\u8fdb\u4e00\u6b65\u4e86\u89e3 HBV \u68c0\u6d4b\uff0c\u8bf7\u89c2\u770b\u7531 Thompson \u6559\u6388\u548c Douglas \u526f\u6559\u6388 \u4e3b\u8bb2\u7684\u5b8c\u6574\u7f51\u7edc\u7814\u8ba8\u4f1a<\/a>\uff0c\u6216\u67e5\u9605 Lab Insights \u4e2d\u7684\u5176\u4ed6\u76f8\u5173\u6587\u7ae0<\/a>\u3002<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

\u5728\u5168\u7403\u4e3a\u964d\u4f4e\u4e59\u578b\u809d\u708e (HBV) \u6b7b\u4ea1\u7387\u7684\u536b\u751f\u884c\u52a8\u4e0d\u65ad\u5347\u7ea7\u4e4b\u9645\uff0c\u6765\u81ea\u4e16\u754c\u5404\u5730\u7684\u5b9e\u9a8c\u5ba4\u548c\u533b\u7597\u9886\u57df\u7684\u9886\u5bfc\u8005\u53ca\u4e13\u5bb6\u6b63\u5f00\u53d1\u548c\u5e94\u7528\u65b0\u578b\u751f\u7269\u6807\u5fd7\u7269\uff0c\u4ee5\u6307\u5bfc\u8bca\u7597\u7b56\u7565\u3002\u5728 Roche Diagnostics \u6700\u8fd1\u4e3e\u529e\u7684\u4e00\u573a\u7f51\u7edc\u7814\u8ba8\u4f1a\u4e0a\uff0c\u6765\u81ea\u6fb3\u5927\u5229\u4e9a\u7684\u4e24\u540d\u75c5\u6bd2\u5b66\u4e13\u5bb6\u8ba8\u8bba\u4e86 HBV \u8bca\u65ad\u7684\u6700\u65b0\u8fdb\u5c55\u53ca\u5176\u5728\u6fb3\u5927\u5229\u4e9a\u7684\u6f5c\u5728\u5e94\u7528\u3002 \u4ee5\u4e0b\u662f\u672c\u6b21\u7f51\u7edc\u7814\u8ba8\u4f1a\u7684\u90e8\u5206\u5173\u952e\u8981\u70b9\u3002\u4e3b\u8bb2\u5609\u5bbe\u5305\u62ec\uff1a\u58a8\u5c14\u672c\u5927\u5b66\u5723\u6587\u68ee\u7279\u533b\u9662\u80c3\u80a0\u75c5\u5b66\u7cfb\u4e3b\u4efb Alex Thompson \u6559\u6388\uff0c\u4ee5\u53ca\u6fb3\u5927\u5229\u4e9a\u6089\u5c3c\u5927\u5b66\u4e0e The Westmead Institute for Medical Research \u7684 Storr Liver Centre \u7684 Mark Douglas \u526f\u6559\u6388\u3002 \u964d\u4f4e HBV \u7684\u91cd\u8981\u6027 \u5168\u7403\u6709 20 \u4ebf\u4eba\u5728\u5176\u4e00\u751f\u4e2d\u7684\u67d0\u4e2a\u9636\u6bb5\u66fe\u611f\u67d3\u8fc7 HBV\uff0c\u5176\u4e2d\u7ea6 3 \u4ebf\u4eba\u4e3a\u6162\u6027\u611f\u67d3\u8005\uff0cHBV \u6784\u6210\u4e86\u5de8\u5927\u7684\u5168\u7403\u5065\u5eb7\u6311\u6218\u3002\u5982\u679c\u4e0d\u4e88\u6cbb\u7597\uff0c\u591a\u8fbe 40% \u7684\u60a3\u8005\u53ef\u80fd\u6b7b\u4e8e\u75c5\u6bd2\u5bfc\u81f4\u7684\u809d\u786c\u5316\u6216\u809d\u764c\u3002 \u8fd9\u4e5f\u662f\u5404\u516c\u5171\u536b\u751f\u673a\u6784\u5c06 HBV \u4f5c\u4e3a\u91cd\u70b9\u5bf9\u8c61\uff0c\u5f00\u5c55\u5927\u89c4\u6a21\u884c\u52a8\u4ee5\u51cf\u5c11\u751a\u81f3\u6d88\u9664\u8be5\u75c5\u6bd2\u7684\u539f\u56e0\u30022016 \u5e74\uff0c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u5ba3\u5e03\u4e00\u9879\u8ba1\u5212\uff0c\u529b\u4e89\u5230 2030 \u5e74\u5c06 HBV \u611f\u67d3\u51cf\u5c11 90%\uff0c\u76f8\u5173\u7684\u6b7b\u4ea1\u51cf\u5c11 65%\u3002 \u8be5\u8ba1\u5212\u7684\u5173\u952e\u5728\u4e8e\u5728\u5206\u5a29\u524d\u6216\u5206\u5a29\u671f\u95f4\u91cd\u70b9\u963b\u65ad\u6bcd\u5a74\u4f20\u64ad\uff0c\u5e76\u901a\u8fc7\u52a0\u5f3a\u75ab\u82d7\u63a5\u79cd\u3001\u68c0\u6d4b\u548c\u6cbb\u7597\u6765\u51cf\u8f7b\u75be\u75c5\u8d1f\u62c5\u3002 \u5173\u6ce8\u598a\u5a20\u6bcd\u4eb2\u5411\u5a74\u513f\u7684\u5782\u76f4\u4f20\u64ad\uff0c\u5bf9\u5e94\u5bf9\u6162\u6027 HBV \u611f\u67d3\u8fd9\u4e00\u6311\u6218\u5c24\u4e3a\u91cd\u8981\u3002\u6210\u4eba\u611f\u67d3 HBV \u540e\uff0c\u53d1\u5c55\u4e3a\u6162\u6027\u611f\u67d3\u7684\u6982\u7387\u4ec5\u7ea6\u4e3a 5%\u3002\u4f46\u5728\u51fa\u751f\u524d\u6216\u51fa\u751f\u65f6\u7531\u6bcd\u4eb2\u611f\u67d3 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