{"id":145597,"date":"2024-08-23T06:17:53","date_gmt":"2024-08-23T06:17:53","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e4%ba%86%e8%a7%a3-hba1c-%e5%9c%a8%e7%b3%96%e5%b0%bf%e7%97%85%e7%ae%a1%e7%90%86%e4%b8%ad%e7%9a%84%e4%bd%9c%e7%94%a8%ef%bc%9a%e4%b8%8e-aw-tar-choon-%e6%95%99%e6%8e%88%e7%9a%84%e9%97%ae%e7%ad%94\/"},"modified":"2026-01-22T04:46:16","modified_gmt":"2026-01-22T04:46:16","slug":"understanding-the-role-of-hba1c-in-diabetes-management-qa-with-prof-aw-tar-choon-part-1","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/zhcn\/operations\/immunoassay\/understanding-the-role-of-hba1c-in-diabetes-management-qa-with-prof-aw-tar-choon-part-1\/","title":{"rendered":"\u4e86\u89e3 HbA1c \u5728\u7cd6\u5c3f\u75c5\u7ba1\u7406\u4e2d\u7684\u4f5c\u7528\uff1a\u4e0e Aw Tar Choon \u6559\u6388\u7684\u95ee\u7b54\uff08\u7b2c 1 \u90e8\u5206\uff09"},"content":{"rendered":"

\u5728\u672c\u671f\u5173\u4e8e\u751f\u7269\u6807\u5fd7\u7269 HbA1c \u7684\u7b2c 2 \u90e8\u5206\u7cfb\u5217\u4e2d\uff0cLab Insight \u56e2\u961f\u91c7\u8bbf\u4e86\u65b0\u52a0\u5761 Changi General Hospital \u5316\u5b66\u75c5\u7406\u79d1\u4e3b\u4efb Aw Tar Choon \u6559\u6388\u3002\u4ed6\u662f\u591a\u672c\u671f\u520a\u7684\u7f16\u59d4\uff0c\u5305\u62ec\u300a\u65b0\u52a0\u5761\u533b\u7597\u4fdd\u5065\u5b66\u4f1a\u4f1a\u520a\u300b\u3001\u300a\u9a6c\u6765\u897f\u4e9a\u533b\u5b66\u79d1\u5b66\u6742\u5fd7\u300b\u4e0e\u300a\u6fc0\u7d20\u75be\u75c5\u4e0e\u5185\u5206\u6ccc\u7814\u7a76\u6742\u5fd7\u300b\u3002Aw \u6559\u6388\u7684\u7814\u7a76\u5173\u6ce8\u9886\u57df\u5305\u62ec\u5185\u5206\u6ccc\u7d0a\u4e71\uff08\u7532\u72b6\u817a\u75be\u75c5\u3001\u7cd6\u5c3f\u75c5\uff09\u3001\u514d\u75ab\u5206\u6790\u3001\u764c\u75c7\u548c\u5fc3\u810f\u751f\u7269\u6807\u5fd7\u7269\u3002<\/p>\n

\u5728\u672c\u95ee\u7b54\u7684\u7b2c 1 \u90e8\u5206\uff0c\u6211\u4eec\u5c06\u4e86\u89e3 HbA1c \u68c0\u6d4b\u7684\u91cd\u8981\u6027\uff0c\u4ee5\u53ca\u6709\u5173\u8fd9\u79cd\u751f\u7269\u6807\u5fd7\u7269\u7684\u4e00\u4e9b\u9c9c\u4e3a\u4eba\u77e5\u7684\u4e8b\u5b9e\u3002<\/p>\n

HbA1c \u4e3a\u4f55\u5728\u7cd6\u5c3f\u75c5\u7ba1\u7406\u4e2d\u81f3\u5173\u91cd\u8981\uff1f<\/strong><\/p>\n

\u7cd6\u5c3f\u75c5\u662f\u4e00\u79cd\u6162\u6027\u9ad8\u8840\u7cd6\u75c7\u3002\u8bb8\u591a\u4eba\u53ef\u80fd\u4f1a\u8003\u8651\u4f7f\u7528\u8461\u8404\u7cd6\u6c34\u5e73\uff08\u8461\u8404\u7cd6\u6c34\u5e73\u5177\u6709\u591a\u53d8\u6027\uff0c\u5e76\u968f\u996e\u98df\u800c\u6ce2\u52a8\uff09\u4f5c\u4e3a\u6307\u6807\uff0c\u4f46\u5176\u68c0\u6d4b\u65b9\u6cd5\u5404\u5f02\u3001\u51c6\u786e\u6027\u4e0d\u4e00\uff0c\u4e14\u7ed3\u679c\u89e3\u8bfb\u5f80\u5f80\u5b58\u5728\u4e3b\u89c2\u6027\u3002\u6bcf\u5f53\u9aa8\u9ad3\u4ea7\u751f\u65b0\u7684\u8840\u7ea2\u86cb\u767d\u65f6\uff0c\u4ee5\u53ca\u4e0e\u8461\u8404\u7cd6\u63a5\u89e6\u65f6\uff0c\u5c31\u4f1a\u4ea7\u751f\u7cd6\u5316\u8840\u7ea2\u86cb\u767d (HbA1c)\uff0c\u4ece\u800c\u4e0d\u53ef\u9006\u5730\u5f62\u6210 HbA1C\u3002<\/p>\n

HbA1c \u5b58\u5728\u4e8e\u7ea2\u7ec6\u80de (RBC)\uff0c\u7531\u4e8e\u7ea2\u7ec6\u80de\u5b58\u6d3b\u671f\u7ea6\u4e3a 120 \u5929\uff0c\u5b83\u80fd\u53cd\u6620\u4e2a\u4f53\u8fc7\u53bb 8-10 \u5468\u5185\u7684\u8840\u7cd6\u6574\u4f53\u72b6\u51b5\uff0c\u56e0\u800c\u662f\u4e00\u79cd\u66f4\u4f18\u8d8a\u7684\u8840\u7cd6\u6c34\u5e73\u8bc4\u4f30\u6307\u6807\u3002<\/p>\n

\u5173\u4e8e HbA1c\uff0c\u5b9e\u9a8c\u5ba4\u5e94\u6ce8\u610f\u54ea\u4e9b\u9c9c\u4e3a\u4eba\u77e5\u7684\u4e8b\u5b9e\uff1f<\/strong><\/p>\n

\u6211\u4eec\u5fc5\u987b\u660e\u786e\uff1a\u5982\u4eca\u6211\u4eec\u5df2\u77e5\u6089\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\u7684\u672c\u8d28\u3002\u9664\u4e86\u8461\u8404\u7cd6\u5916\uff0c\u5206\u5b50 \u03b2 \u94fe\u7684 N \u7aef\u5b50\u7684\u524d\u4e94\u4e2a\u6216\u516d\u4e2a\u6c28\u57fa\u9178\u4e5f\u662f\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\u7684\u6784\u6210\u6210\u5206\u3002\u6d4b\u91cf\u603b\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\u548c\/\u6216\u8272\u8c31\u4e0a\u5355\u4e2a\u5cf0\u7684\u6d4b\u5b9a\u6cd5\u4e0d\u518d\u662f\u9996\u9009\u3002<\/p>\n

\u5176\u6b21\uff0c\u8840\u7ea2\u86cb\u767d\u75c5\u4f1a\u5f71\u54cd HbA1c \u7684\u6d4b\u91cf\uff0c\u5e76\u4e14\u4e0d\u540c\u68c0\u6d4b\u65b9\u6cd5\u4e5f\u4f1a\u53d7\u5230\u4e0d\u540c\u7684\u5f71\u54cd\uff0c\u5373\u4f7f\u662f\u9ad8\u6548\u6db2\u76f8\u8272\u8c31 (HPLC) \u4e5f\u65e0\u6cd5\u907f\u514d\u5176\u5e72\u6270\u3002\u5373\u4f7f\u8840\u7ea2\u86cb\u767d\u75c5\u53ef\u80fd\u5f71\u54cd HbA1c \u7684\u6d4b\u91cf\uff0c\u4f46\u901a\u5e38\u4ec5\u5728\u7eaf\u5408\u5b50\u72b6\u6001\u4e0b\u624d\u4f1a\u4ea7\u751f\u5f71\u54cd\u3002\u6742\u5408\u5b50\u8840\u7ea2\u86cb\u767d\u75c5\u5bf9\u6d4b\u91cf\u7684\u5f71\u54cd\u8f83\u5c0f\uff0c\u5bf9\u4e0b\u6e38\u7684\u5f71\u54cd\u66f4\u662f\u5fae\u4e4e\u5176\u5fae\u3002\u4e3a\u8ba9\u60a3\u8005\u9002\u5e94\u8fd9\u4e00\u7279\u70b9\uff0c\u6700\u597d\u4ee5\u60a3\u8005\u81ea\u8eab\u4f5c\u4e3a\u5bf9\u7167\u3002\u4f7f\u7528\u6301\u7eed\u8461\u8404\u7cd6\u76d1\u6d4b\u4eea\uff0c\u53ef\u4ee5\u4e86\u89e3\u60a3\u8005 [\u8461\u8404\u7cd6\u6c34\u5e73] \u662f\u5426\u5904\u4e8e\u826f\u597d\u63a7\u5236\u72b6\u6001\u3002\u5982\u4eca\uff0c\u6301\u7eed\u8461\u8404\u7cd6\u76d1\u6d4b\u7684\u91c7\u7528\u53d7\u5230\u5176\u4ef7\u683c\u6807\u7b7e\u7684\u9650\u5236\uff0c\u4f46\u6211\u76f8\u4fe1\u60c5\u51b5\u4f1a\u6709\u6240\u597d\u8f6c\u3002<\/p>\n

\u80fd\u5426\u5206\u4eab\u4e00\u4e0b\u7cd6\u5c3f\u75c5\u63a7\u5236\u4e0e\u5e76\u53d1\u75c7\u8bd5\u9a8c (DCCT) \u548c\u82f1\u56fd\u524d\u77bb\u6027\u7cd6\u5c3f\u75c5\u7814\u7a76 (UKPDS) \u8fd9\u4e24\u9879\u6807\u5fd7\u6027\u7814\u7a76\u7684\u5173\u952e\u53d1\u73b0\uff1f<\/strong><\/p>\n

DCCT \u548c UKPDS \u5747\u4e3a\u5728 1990 \u5e74\u4ee3\u5b8c\u6210\u7684\u6807\u5fd7\u6027\u7814\u7a76\uff0c\u6b64\u7c7b\u7814\u7a76\u663e\u793a\u4e86\u5f3a\u5316\u8840\u8461\u8404\u7cd6\u5728\u63a7\u5236\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e2d\u7684\u8840\u8461\u8404\u7cd6\u6c34\u5e73\u7684\u91cd\u8981\u4f5c\u7528\uff0c\u56e0\u6b64\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002\u8bd5\u9a8c\u8868\u660e\uff0c\u5bf9\u4e8e\u8fd9\u4e24\u79cd\u7c7b\u578b\u7684\u7cd6\u5c3f\u75c5\uff0c\u8840\u8461\u8404\u7cd6\u63a7\u5236\u4e0d\u826f\u4e0e\u5e38\u89c1\u7684\u5fae\u8840\u7ba1\u5e76\u53d1\u75c7\uff08\u5982\u89c6\u7f51\u819c\u75c5\u3001\u795e\u7ecf\u75c5\u53d8\u548c\u80be\u75c5\uff09\u4e4b\u95f4\u5b58\u5728\u660e\u663e\u8054\u7cfb\u3002\u5bf9\u4e8e\u8840\u7cd6\u63a7\u5236\u8f83\u5dee\u7684\u53d7\u8bd5\u8005\uff0c\u5176\u7ed3\u5c40\u6bd4\u8840\u7cd6\u63a7\u5236\u8f83\u597d\u7684\u53d7\u8bd5\u8005\u66f4\u5dee\u3002<\/p>\n

\u8fd9\u4e9b\u8bd5\u9a8c\u4e3a\u5f53\u4eca\u7cd6\u5c3f\u75c5\u4e34\u5e8a\u8bd5\u9a8c\u7684\u8bbe\u8ba1\u5f00\u8f9f\u4e86\u9053\u8def\uff1b\u6b64\u540e\u7684\u4e00\u7cfb\u5217\u7814\u7a76\u8fdb\u4e00\u6b65\u63ed\u793a\u4e86\u7cd6\u5c3f\u75c5\u4e0e\u66f4\u591a\u5e76\u53d1\u75c7\u4e4b\u95f4\u7684\u5173\u8054\uff0c\u4f8b\u5982\u7cd6\u5c3f\u75c5\u60a3\u8005\u5fc3\u810f\u8870\u7aed\u7684\u53d1\u751f\u4f1a\u52a0\u901f\u3002<\/p>\n

\u60a8\u5982\u4f55\u786e\u4fdd\u4e0d\u540c\u5b9e\u9a8c\u5ba4\u7684\u7ed3\u679c\u4e0e DCCT \u4e2d\u62a5\u544a\u7684\u7ed3\u679c\u76f8\u5f53\uff1f<\/strong><\/p>\n

\u66f4\u51c6\u786e\u7684\u8bf4\u6cd5\u662f\uff0c\u6211\u4eec\u73b0\u5728\u5df2\u901a\u8fc7\u53c2\u8003\u65b9\u6cd5\u3001\u6bdb\u7ec6\u7ba1\u7535\u6cf3\u548c\u8d28\u8c31\u6cd5\u7b49\u6280\u672f\uff0c\u5b9e\u73b0\u4e86\u68c0\u6d4b\u7ed3\u679c\u7684\u6807\u51c6\u5316\u7edf\u4e00\u3002\u6bdb\u7ec6\u7ba1\u7535\u6cf3\u5206\u79bb A1c \u7247\u6bb5\uff0c\u7136\u540e\u901a\u8fc7\u8d28\u91cf\u7535\u79bb\uff08\u4ee5\u8d28\u8c31\u7684\u5f62\u5f0f\uff09\u5bf9\u5176\u8fdb\u884c\u6d4b\u5b9a\u3002\u8fd9\u662f\u53c2\u8003\u65b9\u6cd5\u3002\u5c31\u53ef\u7528\u7684\u53c2\u8003\u65b9\u6cd5\u800c\u8a00\uff0c\u76ee\u524d\u8ba4\u4e3a\u6bdb\u7ec6\u7ba1\u7535\u6cf3\u5c5e\u4e8e\u91d1\u6807\u51c6\u3002<\/p>\n

\u5f53\u7136\uff0c\u8f6c\u8bca\u5b9e\u9a8c\u5ba4\u4e5f\u53ef\u4ee5\u53c2\u4e0e NGSP \u9879\u76ee\u3002<\/p>\n

\u8bf4\u5230 NGSP \u9879\u76ee\uff0c\u60a8\u80fd\u5206\u4eab\u66f4\u591a\u6709\u5173 HbA1c \u5404\u79cd\u8d28\u91cf\u63a7\u5236\u8bc4\u4f30\u7684\u4fe1\u606f\u5417\uff1f<\/strong><\/p>\n

\u6700\u597d\u7684\u6807\u51c6\u5316\u9879\u76ee\u662f\u7531 NGSP \u8fd0\u884c\u7684\u9879\u76ee\uff0c\u8be5\u9879\u76ee\u7684\u4eae\u70b9\u4e4b\u4e00\u5728\u4e8e\u5176\u63a8\u884c\u53cc\u8f68\u5236\uff1a\u76d1\u6d4b\u4e0e\u8ba4\u8bc1\u3002\u5728\u76d1\u6d4b\u9879\u76ee\u4e2d\uff0c\u6bcf\u8f6e\u8d28\u8bc4\u5305\u542b 20 \u4e2a\u6837\u672c\uff0c\u6bcf\u5e74\u8fdb\u884c 4 \u8f6e\uff1b\u5b9e\u9a8c\u5ba4\u9700\u5728 2 \u5929\u5185\u5b8c\u6210\u5176\u4e2d 10 \u4e2a\u6837\u672c\u7684\u68c0\u6d4b\u3002\u8ba4\u8bc1\u9879\u76ee\u8d28\u8bc4\u6bcf\u5e74\u8fdb\u884c\u4e00\u6b21\uff0c\u63d0\u4f9b 40 \u4e2a\u6837\u672c\uff0c\u5b9e\u9a8c\u5ba4\u9700\u5728 5 \u5929\u5185\u5b8c\u6210\u5176\u4e2d 8 \u4e2a\u6837\u672c\u7684\u68c0\u6d4b\u3002\u4f46\u662f\uff0c\u5982\u679c\u4e0d\u53c2\u52a0\u00a0NGSP\uff0c\u53c2\u52a0 College of American Pathologists (CAP) \u7684\u8c03\u67e5\u4e5f\u5df2\u7ecf\u8db3\u591f\u3002<\/p>\n

\u5728\u65b0\u52a0\u5761\uff0c\u536b\u751f\u90e8 (MOH) \u8981\u6c42\u6211\u4eec\u5fc5\u987b\u53c2\u4e0e\u5176\u9879\u76ee\uff0c\u5305\u62ec\u6bcf\u5e74 2 \u6b21\u8d28\u8bc4\uff0c\u6bcf\u6b21\u8d28\u8bc4 1 \u4efd\u6837\u672c\u3002<\/p>\n

\n

\u67e5\u770b\u95ee\u7b54<\/a>\u7684\u7b2c 2 \u90e8\u5206\uff0c\u83b7\u5f97 Aw Tar Choon \u6559\u6388\u63d0\u4f9b\u7684\u66f4\u591a\u89c1\u89e3\u3002\u82e5\u60f3\u8fdb\u4e00\u6b65\u4e86\u89e3 HbA1c \u68c0\u6d4b\u5982\u4f55\u4e3a\u60a8\u7684\u5b9e\u9a8c\u5ba4\u5e26\u6765\u4ef7\u503c\u53ca\u5176\u5177\u4f53\u5b9e\u65bd\u65b9\u6848\uff0c\u8bf7\u8054\u7cfb Roche Diagnostics Asia Pacific \u6838\u5fc3\u5b9e\u9a8c\u5ba4\u4e1a\u52a1\u7ecf\u7406 Yingli Huang (yingli.huang@roche.com)\u3002\u00a0<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

\u5728\u672c\u671f\u5173\u4e8e\u751f\u7269\u6807\u5fd7\u7269 HbA1c \u7684\u7b2c 2 \u90e8\u5206\u7cfb\u5217\u4e2d\uff0cLab Insight \u56e2\u961f\u91c7\u8bbf\u4e86\u65b0\u52a0\u5761 Changi General Hospital \u5316\u5b66\u75c5\u7406\u79d1\u4e3b\u4efb Aw Tar Choon \u6559\u6388\u3002\u4ed6\u662f\u591a\u672c\u671f\u520a\u7684\u7f16\u59d4\uff0c\u5305\u62ec\u300a\u65b0\u52a0\u5761\u533b\u7597\u4fdd\u5065\u5b66\u4f1a\u4f1a\u520a\u300b\u3001\u300a\u9a6c\u6765\u897f\u4e9a\u533b\u5b66\u79d1\u5b66\u6742\u5fd7\u300b\u4e0e\u300a\u6fc0\u7d20\u75be\u75c5\u4e0e\u5185\u5206\u6ccc\u7814\u7a76\u6742\u5fd7\u300b\u3002Aw \u6559\u6388\u7684\u7814\u7a76\u5173\u6ce8\u9886\u57df\u5305\u62ec\u5185\u5206\u6ccc\u7d0a\u4e71\uff08\u7532\u72b6\u817a\u75be\u75c5\u3001\u7cd6\u5c3f\u75c5\uff09\u3001\u514d\u75ab\u5206\u6790\u3001\u764c\u75c7\u548c\u5fc3\u810f\u751f\u7269\u6807\u5fd7\u7269\u3002 \u5728\u672c\u95ee\u7b54\u7684\u7b2c 1 \u90e8\u5206\uff0c\u6211\u4eec\u5c06\u4e86\u89e3 HbA1c 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