{"id":145629,"date":"2023-05-26T03:04:59","date_gmt":"2023-05-26T03:04:59","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e4%b8%8e%e6%bf%80%e7%b4%a0%e6%b2%bb%e7%96%97%e5%8f%8a%e5%a6%8a%e5%a8%a0%e7%9b%b8%e5%85%b3%e7%9a%84-vte%ef%bc%9alai-heng-lee-%e6%95%99%e6%8e%88%e8%ae%ba%e9%a3%8e%e9%99%a9%e4%b8%8e%e7%ae%a1%e7%90%86\/"},"modified":"2026-01-22T05:00:57","modified_gmt":"2026-01-22T05:00:57","slug":"vte-associated-with-hormone-therapy-and-pregnancy-assoc-prof-lai-heng-lee-on-risk-and-management","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/zhcn\/disease-area\/womens-health\/vte-associated-with-hormone-therapy-and-pregnancy-assoc-prof-lai-heng-lee-on-risk-and-management\/","title":{"rendered":"\u4e0e\u6fc0\u7d20\u6cbb\u7597\u53ca\u598a\u5a20\u76f8\u5173\u7684 VTE\uff1aLai Heng Lee \u6559\u6388\u8bba\u98ce\u9669\u4e0e\u7ba1\u7406"},"content":{"rendered":"

\u5728 Roche Diagnostics \u53d1\u8d77\u7684\u5e74\u5ea6 pro-COAG \u6d3b\u52a8<\/a>\uff082022 \u5e74\uff09\u4e0a\uff0cLai Heng Lee \u526f\u6559\u6388\u4f5c\u4e86\u7cbe\u5f69\u62a5\u544a\uff0c\u6df1\u5165\u8bb2\u89e3\u4e86\u4e0e\u6fc0\u7d20\u6cbb\u7597\u53ca\u598a\u5a20\u76f8\u5173\u7684\u598a\u5a20 VTE\uff08\u9759\u8109\u8840\u6813\u6813\u585e\uff09\u98ce\u9669\u3002\u4ee5\u4e0b\u662f\u90e8\u5206\u5173\u952e\u8981\u70b9\u3002<\/p>\n

\u4e0e\u6fc0\u7d20\u76f8\u5173\u7684\u9759\u8109\u8840\u6813\u6813\u585e (VTE)<\/h2>\n

\u5728\u5e74\u8f7b\u5973\u6027\u4e2d\uff0cVTE \u7684\u5e74\u53d1\u75c5\u7387\u901a\u5e38\u4e3a 1\/10,000\u3002\u7136\u800c\uff0c\u8054\u5408\u53e3\u670d\u907f\u5b55\u836f (COC) \u548c\u6fc0\u7d20\u66ff\u4ee3\u7597\u6cd5 (HRT) \u7b49\u6fc0\u7d20\u6cbb\u7597\u4f1a\u589e\u52a0\u53d1\u751f VTE \u7684\u98ce\u9669\u3002\u4e0e\u672a\u4f7f\u7528\u8005\u76f8\u6bd4\uff0cCOC \u5c06 VTE \u98ce\u9669\u589e\u52a0\u7ea6 2 \u81f3 4 \u500d\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u7edd\u5bf9\u98ce\u9669\u4ecd\u7136\u8f83\u4f4e\uff0c\u4f30\u8ba1\u5c0f\u4e8e 0.1%\u3002\u5728 HRT \u4e2d\uff0cVTE \u98ce\u9669\u7684\u589e\u52a0\u76f8\u5bf9\u8f83\u5c0f\uff0c\u7ea6\u4e3a 1.5 \u81f3 2 \u500d\u3002<\/p>\n

COC \u53ef\u5f15\u8d77\u51dd\u8840\u6b62\u8840\u7cfb\u7edf\u7684\u6539\u53d8\uff0c\u5bfc\u81f4\u9ad8\u51dd\u72b6\u6001\uff0c\u4e3b\u8981\u901a\u8fc7\u8bf1\u5bfc\u4fc3\u51dd\u86cb\u767d\u6c34\u5e73\u5347\u9ad8\uff0c\u5305\u62ec\u7ea4\u7ef4\u86cb\u767d\u539f\u3001\u51dd\u8840\u9176\u539f\u4ee5\u53ca\u51dd\u8840\u56e0\u5b50 VII\u3001VIII \u548c X \u6c34\u5e73\u7684\u589e\u52a0\u3002\u5b83\u8fd8\u4f1a\u964d\u4f4e\u5929\u7136\u6297\u51dd\u5242\uff08\u4f8b\u5982\u6297\u51dd\u8840\u9176\u548c\u86cb\u767dS\u00a0(PS)\uff09\u7684\u6c34\u5e73\u3002\u7531\u4e8e PS \u662f\u86cb\u767d C (PC) \u7684\u8f85\u56e0\u5b50\uff0cPS \u6d3b\u6027\u964d\u4f4e\u53ef\u5bfc\u81f4\u83b7\u5f97\u6027\u6d3b\u5316\u86cb\u767d C \u62b5\u6297\u72b6\u6001 (APC)\u3002<\/p>\n

\u591a\u9879\u7814\u7a76\u8868\u660e\uff0cCOC \u76f8\u5173\u7684 VTE \u98ce\u9669\u4e0e\u5176\u836f\u7247\u7684\u6210\u5206\u6784\u6210\u6709\u5173\u3002\u8f83\u9ad8\u5242\u91cf\u7684\u96cc\u6fc0\u7d20\uff08>30 \u03bcg \u7094\u96cc\u9187\uff09\u4ee5\u53ca\u542b\u6709\u975e\u5de6\u7094\u8bfa\u5b55\u916e\u7c7b\u5b55\u6fc0\u7d20\u7684 COC \u5236\u5242\uff08\u4f8b\u5982\u5c48\u87ba\u916e\u3001\u53bb\u6c27\u5b55\u70ef\u3001\u5b55\u4e8c\u70ef\u916e\u548c\u918b\u9178\u73af\u4e19\u5b55\u916e\uff09\u5747\u4e0e\u8f83\u9ad8\u7684 VTE \u98ce\u9669\u76f8\u5173\u3002\u4e0e\u4e4b\u76f8\u540c\uff0cVTE \u7684\u98ce\u9669\u4e5f\u56e0 HRT \u4ea7\u54c1\u7684\u7ec4\u6210\u800c\u5f02\u3002\u916f\u5316\u96cc\u6fc0\u7d20 (EE) \u548c\u7ed3\u5408\u96cc\u9a6c\u96cc\u6fc0\u7d20 (CEE) \u5747\u4e0e VTE \u7684\u663e\u8457\u589e\u52a0\u98ce\u9669\u76f8\u5173\uff0c\u4f46\u4e0e CEE \u76f8\u6bd4\uff0cEE \u7684\u98ce\u9669\u4f3c\u4e4e\u66f4\u4f4e\u3002\u4eba\u4eec\u8fc7\u53bb\u8ba4\u4e3a\uff0c\u5728\u96cc\u6fc0\u7d20\u57fa\u7840\u4e0a\u52a0\u7528\u5b55\u916e\uff0c\u76f8\u8f83\u5355\u7528\u96cc\u6fc0\u7d20\u4f1a\u589e\u52a0 VTE \u98ce\u9669\uff0c\u4f46\u8fd1\u671f\u7684\u7cfb\u7edf\u7efc\u8ff0\u548c\u835f\u8403\u5206\u6790\u5e76\u672a\u8bc1\u5b9e\u5728\u96cc\u6fc0\u7d20\u57fa\u7840\u4e0a\u52a0\u7528\u5b55\u916e\u4f1a\u5e26\u6765\u663e\u8457\u7684\u989d\u5916 VTE \u98ce\u9669\u3002<\/p>\n

\u6ce8\u5c04\u7528\u5b55\u6fc0\u7d20\u3001\u8d34\u5242\u548c\u9634\u9053\u73af\u7b49\u975e\u53e3\u670d\u66ff\u4ee3\u5236\u5242\uff0c\u4e5f\u4e0e VTE \u98ce\u9669\u589e\u52a0\u6709\u5173\u3002\u4e0e\u672a\u4f7f\u7528\u8005\u76f8\u6bd4\uff0c\u4f9d\u6258\u5b55\u70ef\u7684\u5b55\u6fc0\u7d20\u5355\u836f\u76ae\u4e0b\u690d\u5165\u5242\u7684 VTE \u98ce\u9669\u589e\u52a0 1.4 \u500d\uff0c\u4f46\u7edd\u5bf9\u98ce\u9669\u4ecd\u7136\u8f83\u5c0f\uff0c\u4e3a\u6bcf 10,000 \u66b4\u9732\u5e74 1.7 \u4f8b\u3002\u5b55\u916e\u5355\u836f\u5bab\u5185\u8282\u80b2\u5668\u3001\u5b55\u916e\u5355\u836f\u53e3\u670d\u5236\u5242\u6216\u96cc\u6fc0\u7d20\u5355\u836f\u900f\u76ae HRT \u5236\u5242\u4f3c\u4e4e\u4e0e VTE \u98ce\u9669\u589e\u52a0\u65e0\u5173\u3002<\/p>\n

HRT \u6700\u65e9\u4e8e 20 \u4e16\u7eaa 60 \u5e74\u4ee3\u7528\u4e8e\u7edd\u7ecf\u540e\u5987\u5973\uff0c\u4ee5\u9884\u9632\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u548c\u9aa8\u8d28\u758f\u677e\uff0c\u5e76\u51cf\u8f7b\u4e0e\u7edd\u7ecf\u671f\u76f8\u5173\u7684\u75c7\u72b6\u3002\u7136\u800c\uff0c\u76ee\u524d\u7684\u6570\u636e\u6307\u51fa\uff0c\u4e0e HRT \u76f8\u5173\u7684 VTE \u98ce\u9669\u3001\u4e73\u817a\u764c\u4ee5\u53ca\u5bf9\u5fc3\u8840\u7ba1\u75be\u75c5\u7f3a\u4e4f\u4fdd\u62a4\u4f5c\u7528\uff0c\u62b5\u6d88\u4e86\u5176\u51cf\u5c11\u9aa8\u8d28\u758f\u677e\u6240\u5e26\u6765\u7684\u83b7\u76ca\u3002\u6b64\u5916\uff0cHRT \u4f3c\u4e4e\u5e76\u4e0d\u80fd\u6539\u5584\u65e0\u4e34\u5e8a\u75c7\u72b6\u7edd\u7ecf\u540e\u5987\u5973\u7684\u751f\u6d3b\u8d28\u91cf\uff0c\u56e0\u6b64 HRT \u5e94\u4e3b\u8981\u7528\u4e8e\u9700\u8981\u63a7\u5236\u4e34\u5e8a\u75c7\u72b6\u7684\u7edd\u7ecf\u540e\u5987\u5973\u3002<\/p>\n

\u5bf9\u4e8e\u63a5\u53d7\u6fc0\u7d20\u6cbb\u7597\u7684\u5973\u6027\uff0c\u4e86\u89e3\u5176\u4ed6 VTE \u5371\u9669\u56e0\u7d20\u975e\u5e38\u91cd\u8981\uff0c\u56e0\u4e3a\u8fd9\u4e9b\u56e0\u7d20\u53ef\u80fd\u4f1a\u53e0\u52a0\u6216\u534f\u540c\u589e\u52a0 VTE \u98ce\u9669\u300250 \u5c81\u4ee5\u4e0a\u7684\u5973\u6027\uff0c\u5982\u670d\u7528 COC\uff0cVTE \u98ce\u9669\u76f8\u6bd4\u672a\u4f7f\u7528\u8005\u589e\u52a0\u7ea6 6.3 \u500d\uff1b\u5982\u63a5\u53d7 HRT\uff0c\u5219\u589e\u52a0\u7ea6 4 \u500d\u3002\u80a5\u80d6\u548c\u5438\u70df\u540c\u6837\u4f1a\u663e\u8457\u589e\u52a0 VTE \u98ce\u9669\u3002\u56e0\u6b64\uff0c\u5bf9\u60a3\u8005\u63d0\u4f9b\u5065\u5eb7\u751f\u6d3b\u65b9\u5f0f\u7684\u5efa\u8bae\u5341\u5206\u91cd\u8981\uff0c\u9f13\u52b1\u5176\u907f\u514d\u80a5\u80d6\u548c\u5438\u70df\uff0c\u4ee5\u964d\u4f4e\u5728\u4f7f\u7528 COC \u6216 HRT \u671f\u95f4\u53d1\u751f VTE \u7684\u98ce\u9669\u3002\u5982\u679c\u9009\u62e9\u624b\u672f\uff0c\u60a3\u8005\u5e94\u544a\u77e5\u533b\u751f\u81ea\u5df1\u662f\u5426\u6b63\u5728\u63a5\u53d7\u6fc0\u7d20\u6cbb\u7597\u4ee5\u53ca\u662f\u5426\u6709 VTE \u5bb6\u65cf\u53f2\uff0c\u4ee5\u4fbf\u91c7\u53d6\u9002\u5f53\u7684 VTE \u9884\u9632\u63aa\u65bd\u3002<\/p>\n

\u5728\u63a5\u53d7\u6fc0\u7d20\u6cbb\u7597\u7684\u5973\u6027\u9996\u6b21\u53d1\u751f VTE \u4e8b\u4ef6\u540e\uff0c\u590d\u53d1\u6027 VTE \u7d2f\u79ef\u98ce\u9669\u5dee\u5f02\u8f83\u5927\uff1a\u6309\u5e74\u5ea6\u8ba1\u7b97\u7ea6\u4e3a 0.4% \u81f3 5%\uff0c5 \u5e74\u65f6\u7ea6\u4e3a 2.3% \u81f3 9%\u3002\u4e0d\u540c\u7814\u7a76\u4e4b\u95f4\u98ce\u9669\u5dee\u5f02\uff0c\u8fd9\u53ef\u80fd\u4e0e\u7814\u7a76\u5f00\u5c55\u7684\u5e74\u4ee3\u6709\u5173\uff08\u968f\u65f6\u95f4\u63a8\u79fb\u6240\u4f7f\u7528\u7684 COC \u4ee3\u6b21\u4e0d\u540c\uff09\uff0c\u4e5f\u4e0e\u5404\u7814\u7a76\u7eb3\u5165\u6807\u51c6\u7684\u5dee\u5f02\u6709\u5173\uff0c\u4ece\u800c\u5bfc\u81f4\u4e0d\u540c\u7814\u7a76\u4e4b\u95f4\u7684 VTE \u98ce\u9669\u5b58\u5728\u660e\u663e\u7684\u5f02\u8d28\u6027\u3002\u5728\u6700\u65b0\u66f4\u65b0\u7684 REVERSE \u539f\u59cb\u961f\u5217\u4e9a\u7ec4\u5206\u6790\u4e2d\uff0c\u5728 HERDOO2 \u8bc4\u5206\u4f4e\u5371\u7684\u5973\u6027\u4e2d\uff0cCOC \u4f7f\u7528\u8005\u7684\u5e74\u590d\u53d1\u7387\u4e3a 0.4%\uff0c\u672a\u4f7f\u7528 COC \u8005\u4e3a 1.4%\uff1b\u800c\u5728\u9ad8\u5371\u5973\u6027\u4e2d\uff0cCOC \u4f7f\u7528\u8005\u7684\u5e74\u590d\u53d1\u7387\u4e3a 3.5%\uff0c\u672a\u4f7f\u7528 COC \u8005\u4e3a 6.1%\u3002 \u56e0\u6b64\uff0c\u5728\u4e3a\u6b64\u7c7b\u5973\u6027\u51b3\u5b9a\u6297\u51dd\u6cbb\u7597\u7597\u7a0b\u65f6\uff0c\u5fc5\u987b\u7efc\u5408\u8003\u8651\u5176\u4ed6 VTE \u5371\u9669\u56e0\u7d20\u3002<\/p>\n

\u4ee4\u4eba\u5b89\u5fc3\u7684\u662f\uff0c\u5728\u63a5\u53d7\u6cbb\u7597\u5242\u91cf\u6297\u51dd\u671f\u95f4\u7ee7\u7eed\u4f7f\u7528 COC \u8fdb\u884c\u6fc0\u7d20\u6cbb\u7597\u5e76\u4e0d\u4f1a\u589e\u52a0\u590d\u53d1\u98ce\u9669\u3002\u5f53\u505c\u6b62\u6297\u51dd\u6cbb\u7597\u65f6\uff0c\u5e94\u540c\u65f6\u505c\u7528 COC \u6216 HRT\uff0c\u4ee5\u5c3d\u91cf\u964d\u4f4e VTE \u590d\u53d1\u98ce\u9669\u3002\u4e3a\u9884\u9632\u598a\u5a20\uff0c\u53ef\u8003\u8651\u4e0d\u589e\u52a0 VTE \u590d\u53d1\u98ce\u9669\u7684\u5176\u4ed6\u907f\u5b55\u65b9\u5f0f\uff0c\u4f8b\u5982\u5b55\u6fc0\u7d20\u5355\u836f\u5bab\u5185\u8282\u80b2\u5668\u6216\u5b55\u6fc0\u7d20\u5355\u836f\u76ae\u4e0b\u690d\u5165\u5242\u3002\u00a0\u603b\u4f53\u800c\u8a00\uff0c\u5728\u63a5\u53d7\u6fc0\u7d20\u7597\u6cd5\u7684\u5973\u6027\u4e2d\uff0cVTE \u590d\u53d1\u98ce\u9669\u4f30\u8ba1\u503c\u603b\u4f53\u8f83\u4f4e\uff0c\u4ee4\u4eba\u653e\u5fc3\u3002\u5728\u4e0d\u5b58\u5728\u5176\u4ed6\u5371\u9669\u56e0\u7d20\u7684\u60c5\u51b5\u4e0b\uff0c\u5e76\u65e0\u8db3\u591f\u4f9d\u636e\u652f\u6301\u957f\u671f\u6297\u51dd\u6cbb\u7597\u3002<\/p>\n

\u5728\u63a5\u53d7\u6fc0\u7d20\u6cbb\u7597\u7684\u5973\u6027\u4e2d\uff0c\u5177\u6709\u9057\u4f20\u6027\u8840\u6813\u503e\u5411\u6240\u5e26\u6765\u7684\u8840\u6813\u98ce\u9669\u4e5f\u5907\u53d7\u5173\u6ce8\u3002 \u56e0\u5b50 V Leiden (FVL) \u548c\u51dd\u8840\u9176\u539f\u57fa\u56e0\u7a81\u53d8 (PGM) \u662f\u767d\u4eba\u7fa4\u4f53\u4e2d\u5e38\u89c1\u7684\u4e24\u79cd\u8f83\u8f7b\u578b\u9057\u4f20\u6027\u8840\u6813\u6027\u7d20\u8d28\uff0c\u53ef\u4f7f VTE \u98ce\u9669\u589e\u52a0\u7ea6 4 \u81f3 7 \u500d\u3002\u6297\u51dd\u8840\u9176\u3001PC \u548c PS \u7f3a\u4e4f\u867d\u7136\u5c11\u89c1\uff0c\u4f46\u5176\u81f4\u6813\u98ce\u9669\u663e\u8457\u66f4\u9ad8\u3002\u636e\u62a5\u9053\uff0c\u6297\u51dd\u8840\u9176\u7f3a\u4e4f\u75c7\u53ef\u4f7f VTE \u98ce\u9669\u589e\u52a0\u7ea6 50 \u500d\uff0c\u800c PC \u548c PS \u7f3a\u4e4f\u5219\u4e0e VTE \u98ce\u9669\u589e\u52a0\u7ea6 10 \u81f3 15 \u500d\u76f8\u5173\u3002\u56e0\u6b64\uff0c\u5728\u4f7f\u7528 OC \u7684\u5973\u6027\u4e2d\uff0c\u5408\u5e76\u9057\u4f20\u6027\u8840\u6813\u6027\u7d20\u8d28\u4f1a\u663e\u8457\u589e\u52a0\u8840\u6813\u503e\u5411\u98ce\u9669\u3002<\/p>\n

\u518d\u6b21\u5f3a\u8c03\uff0c\u4e86\u89e3\u7edd\u5bf9\u98ce\u9669\u6709\u52a9\u4e8e\u5728\u4e3a\u5177\u6709\u5df2\u77e5\u8840\u6813\u503e\u5411\u4e2a\u4eba\u6216\u5bb6\u65cf\u53f2\u7684\u60a3\u8005\u8fdb\u884c\u7528\u836f\u54a8\u8be2\u65f6\uff0c\u5ba2\u89c2\u5730\u6743\u8861\u5229\u5f0a\u3002\u5728\u670d\u7528 COC \u4e14\u643a\u5e26 FVL \u6216 PGM \u7684\u5973\u6027\u4e2d\uff0cVTE \u7684\u7edd\u5bf9\u98ce\u9669\u7ea6\u4e3a\u6bcf 100 \u4eba\u5e74 0.45\u20132 \u4f8b\uff1b\u4e0e\u598a\u5a20\u76f8\u5173\u98ce\u9669\u76f8\u6bd4\uff0c\u5bf9\u67d0\u4e9b\u5973\u6027\u800c\u8a00\uff0c\u8be5 VTE \u98ce\u9669\u53ef\u80fd\u66f4\u4e3a\u53ef\u63a5\u53d7\u3002\u7136\u800c\uff0c\u5bf9\u4e8e\u66f4\u4e3a\u4e25\u91cd\u7684\u8840\u6813\u503e\u5411\uff0c\u7531\u4e8e\u7f3a\u4e4f\u6709\u529b\u7684\u6570\u636e\uff0c\u5176\u7edd\u5bf9\u98ce\u9669\u62a5\u9053\u4e3a\u6bcf 100 \u4f4d\u53e3\u670d\u907f\u5b55\u836f\u4f7f\u7528\u8005\u4e3a 4.3\u20134.5 \u4f8b\/\u5e74\uff0c\u56e0\u6b64\u5e94\u66f4\u52a0\u8c28\u614e\uff0c\u5e76\u5efa\u8bae\u91c7\u7528\u5176\u4ed6\u66ff\u4ee3\u7684\u907f\u5b55\u65b9\u5f0f\u3002<\/p>\n

\u5373\u4fbf\u5982\u6b64\uff0c\u5728\u4f7f\u7528 COC \u524d\u8fdb\u884c\u5927\u89c4\u6a21\u5e38\u89c4\u8840\u6813\u503e\u5411\u7b5b\u67e5\u5e76\u65e0\u5145\u5206\u4f9d\u636e\uff0c\u56e0\u6b64\u4e0d\u63a8\u8350\u3002\u8fd9\u79cd\u7b5b\u67e5\u7f3a\u4e4f\u6210\u672c\u6548\u76ca\uff0c\u56e0\u4e3a\u9700\u8981\u5bf9\u5927\u91cf\u5973\u6027\u8fdb\u884c\u68c0\u6d4b\uff0c\u5e76\u5efa\u8bae\u5176\u907f\u514d\u4f7f\u7528 COC\uff0c\u624d\u53ef\u80fd\u9884\u9632\u533a\u533a 1 \u4f8b\u8840\u6813\u4e8b\u4ef6\u3002\u6b64\u5916\uff0c\u5bf9\u4e8e\u8f83\u8f7b\u578b\u7684\u8840\u6813\u503e\u5411\uff0c\u5176 VTE \u7edd\u5bf9\u98ce\u9669\u672c\u8eab\u5c31\u8f83\u4f4e\uff0c\u4e14\u591a\u6570 VTE \u4e8b\u4ef6\u53d1\u751f\u5728\u672a\u68c0\u6d4b\u51fa\u9057\u4f20\u6027\u8840\u6813\u6027\u7d20\u8d28\u7684\u5973\u6027\u4e2d\u3002\u7136\u800c\uff0c\u5728\u5f00\u59cb COC \u6cbb\u7597\u524d\uff0c\u5bf9\u67d0\u4e9b\u4eba\u7fa4\u8fdb\u884c\u9009\u62e9\u6027\u68c0\u6d4b\u53ef\u80fd\u6709\u6240\u5e2e\u52a9\uff0c\u4f8b\u5982\u643a\u5e26\u4e0e\u8840\u6813\u98ce\u9669\u663e\u8457\u5347\u9ad8\u76f8\u5173\u7684\u91cd\u5ea6\u8840\u6813\u6027\u7d20\u8d28\uff08\u5982\u6297\u51dd\u8840\u9176\u3001PC\u3001PS \u7f3a\u4e4f\u4ee5\u53ca FV Leiden \u548c FII G20210A \u7eaf\u5408\uff09\u60a3\u8005\u7684\u65e0\u75c7\u72b6\u4e00\u7ea7\u4eb2\u5c5e\u3002<\/p>\n

\u4e0e\u598a\u5a20\u76f8\u5173\u7684\u9759\u8109\u8840\u6813\u6813\u585e<\/h2>\n

\u598a\u5a20\u53ca\u5176\u751f\u7406\u53d8\u5316\u53ef\u5bfc\u81f4\u51dd\u8840\u56e0\u5b50\uff08VII\u3001VIII\u3001X \u53ca\u8840\u7ba1\u6027\u8840\u53cb\u75c5\u56e0\u5b50\uff09\u6c34\u5e73\u5347\u9ad8\uff0c\u540c\u65f6\u5929\u7136\u6297\u51dd\u56e0\u5b50 (PS) \u6c34\u5e73\u4e0b\u964d\u3002\u8fd9\u79cd\u9ad8\u51dd\u72b6\u6001\uff0c\u518d\u52a0\u4e0a\u4e0b\u80a2\u9759\u8109\u6de4\u6ede\u6613\u53d1\u548c\u76c6\u8154\u8840\u7ba1\u5185\u76ae\u635f\u4f24\uff0c\u6784\u6210\u4e86 Virchow \u7ecf\u5178\u4e09\u8054\u5f81\uff08\u9ad8\u51dd\u72b6\u6001\u3001\u8840\u6d41\u6de4\u6ede\u548c\u8840\u7ba1\u58c1\u635f\u4f24\uff09\uff0c\u4e3a\u5f02\u5e38\u9759\u8109\u8840\u6813\u5f62\u6210\u63d0\u4f9b\u4e86\u75c5\u7406\u57fa\u7840\uff0c\u56e0\u800c\u6613\u53d1\u751f VTE\u3002<\/p>\n

\u598a\u5a20\u671f VTE \u7684\u98ce\u9669\u7ea6\u4e3a 1\/1000 \u4f8b\u598a\u5a20\uff0c\u598a\u5a20\u671f\u548c\u4ea7\u540e\u671f VTE \u7684\u53d1\u751f\u7387\u5927\u81f4\u76f8\u5f53\u3002\u7531\u4e8e\u4ea7\u540e\u671f\u77ed\u4e8e\u598a\u5a20\u671f\uff0c\u6bcf\u65e5 VTE \u98ce\u9669\u66f4\u9ad8\uff0c\u8fd9\u79cd\u589e\u52a0\u7684\u98ce\u9669\u53ef\u6301\u7eed\u81f3\u4ea7\u540e 12 \u5468\uff0c\u5176\u4e2d\u5206\u5a29\u540e\u524d 6 \u5468\u98ce\u9669\u6700\u9ad8\u3002<\/p>\n

\u80ba\u6813\u585e (PE) \u82e5\u4e0d\u53ca\u65f6\u6cbb\u7597\u53ef\u5bfc\u81f4 25% \u7684\u60a3\u8005\u6b7b\u4ea1\u3002\u56e0\u6b64\uff0cVTE \u662f\u5bfc\u81f4\u5b55\u4ea7\u5987\u53d1\u75c5\u548c\u6b7b\u4ea1\u7684\u91cd\u8981\u539f\u56e0\uff0c\u5728\u897f\u65b9\u4eba\u7fa4\u4e2d\u7ea6\u5360\u5b55\u4ea7\u5987\u6b7b\u4ea1\u7684 17%\u3002\u4e86\u89e3\u5b55\u671f\u53d1\u751f VTE \u7684\u5371\u9669\u56e0\u7d20\u5e76\u8fdb\u884c\u98ce\u9669\u5206\u5c42\uff0c\u4ee5\u4fbf\u91c7\u53d6\u9002\u5f53\u7684\u8840\u6813\u9884\u9632\u63aa\u65bd\uff0c\u8fd9\u4e00\u70b9\u975e\u5e38\u91cd\u8981\u3002<\/p>\n

\u76ee\u524d\u9488\u5bf9\u598a\u5a20\u76f8\u5173 VTE \u7684 VTE \u98ce\u9669\u5206\u5c42\u548c\u7ba1\u7406\uff0c\u5df2\u6709\u8bb8\u591a\u6307\u5357\u3002\u8fd9\u4e9b\u6307\u5357\u4e3b\u8981\u57fa\u4e8e\u975e\u598a\u5a20\u4eba\u7fa4\u7684\u6570\u636e\u4ee5\u53ca\u897f\u65b9\u4eba\u7fa4\u598a\u5a20\u671f\u60a3\u8005\u7684\u75c5\u4f8b\u7cfb\u5217\u7814\u7a76\u3002\u56e0\u6b64\uff0c\u57fa\u4e8e\u672c\u5730\u6570\u636e\u5236\u5b9a\u672c\u5730\u5316\u6307\u5357\u5c24\u4e3a\u91cd\u8981\u3002\u5728\u65b0\u52a0\u5761\uff0c\u5185\u79d1\u533b\u5e08\u5206\u4f1a\u4e0e\u5987\u4ea7\u79d1\u533b\u5b66\u9662\u5171\u540c\u5ba1\u67e5\u8fd9\u4e9b\u6307\u5357\u53ca\u5f53\u524d\u5f53\u5730\u6570\u636e\uff0c\u5236\u5b9a\u4e86\u4e0e\u598a\u5a20\u76f8\u5173 VTE \u7ba1\u7406\u7684\u5171\u8bc6\u5efa\u8bae\u3002VTE \u98ce\u9669\u5206\u5c42\u53c2\u8003\u91c7\u7528\u4e86\u82f1\u56fd\u7687\u5bb6\u5987\u4ea7\u79d1\u5b66\u9662 Greentop \u7b2c 37a \u53f7\u6307\u5357\uff0c\u5e76\u6839\u636e\u672c\u5730\u6570\u636e\u548c\u4e34\u5e8a\u533b\u751f\u7684\u610f\u89c1\u4f5c\u4e86\u76f8\u5e94\u8c03\u6574\u3002<\/p>\n

\u6307\u5357\u4e2d\u5217\u793a\u7684 VTE \u5371\u9669\u56e0\u7d20\u5305\u62ec\uff1a\u65e2\u5f80 VTE \u53f2\u3001\u9057\u4f20\u6027\u8840\u6813\u503e\u5411\u3001\u60a3\u8005\u5df2\u6709\u7684\u57fa\u7840\u5371\u9669\u56e0\u7d20\u3001\u4ea7\u79d1\u76f8\u5173\u5371\u9669\u56e0\u7d20\u4ee5\u53ca\u5176\u4ed6\u4e00\u8fc7\u6027\u5371\u9669\u56e0\u7d20\u3002\u6bcf\u4e2a\u5371\u9669\u56e0\u7d20\u7684\u5f97\u5206\u5747\u6839\u636e\u5176\u8840\u6813\u98ce\u9669\u6743\u91cd\u786e\u5b9a\u3002\u8840\u6813\u9884\u9632\u7684\u5efa\u8bae\u53d6\u51b3\u4e8e\u60a3\u8005\u603b\u5206\u6216\u98ce\u9669\u8bc4\u5206\u3002\u56e0\u6b64\uff0c\u4e00\u65e6\u786e\u8bca\u598a\u5a20\uff0c\u82e5\u5b55\u671f\uff08\u4ea7\u524d\uff09\u603b\u8bc4\u5206 \u22654 \u5206\uff0c\u5373\u5e94\u8003\u8651\u542f\u52a8\u4ea7\u524d\u8840\u6813\u9884\u9632\uff1b\u5bf9\u4e8e\u603b\u8bc4\u5206\u4e3a 3 \u5206 \u7684\u5b55\u5987\uff0c\u5219\u4ece\u5b55 28 \u5468\u8d77\u8003\u8651\u7ed9\u4e88\u8840\u6813\u9884\u9632\uff1b\u4ea7\u540e\u7684\u8840\u6813\u9884\u9632\u7b56\u7565\u540c\u6837\u4f9d\u636e\u8be5\u8bc4\u5206\u77e9\u9635\u5236\u5b9a\u3002<\/p>\n

\u7531\u4e8e VTE \u98ce\u9669\u5b58\u5728\u52a8\u6001\u53d8\u5316\uff0c\u4f1a\u968f\u7740\u598a\u5a20\u8fdb\u5c55\u4e2d\u65b0\u5371\u9669\u56e0\u7d20\u7684\u51fa\u73b0\u6216\u65e2\u5f80\u5371\u9669\u56e0\u7d20\u7684\u6d88\u9000\u800c\u6539\u53d8\uff0c \u56e0\u6b64\u5728\u6574\u4e2a\u598a\u5a20\u671f\u548c\u4ea7\u8925\u671f\u7684\u4e0d\u540c\u65f6\u95f4\u70b9\u53cd\u590d\u8bc4\u4f30 VTE \u98ce\u9669\u975e\u5e38\u91cd\u8981\u3002\u8bc4\u4f30\u51fa\u8840\u98ce\u9669\u4e5f\u5f88\u91cd\u8981\u3002\u5982\u679c\u60a3\u8005\u4e0d\u9002\u5408\u6297\u51dd\u9884\u9632\uff0c\u5219\u53ef\u4ee5\u8003\u8651\u4f7f\u7528\u52a0\u538b\u88c5\u7f6e\u6216\u5f39\u529b\u889c\u8fdb\u884c\u673a\u68b0\u9884\u9632\u6cbb\u7597\u3002<\/p>\n

\u65b0\u52a0\u5761\u5171\u8bc6\u5efa\u8bae\u4e2d\u7684\u8c03\u6574\uff0c\u4f53\u73b0\u5728\u9057\u4f20\u6027\u8840\u6813\u503e\u5411\u53ca\u5b55\u4ea7\u5987\u5e74\u9f84\u589e\u52a0\u6240\u8d4b\u4e88\u7684\u6743\u91cd\u5206\u503c\u4e0a\u3002\u4e0e\u897f\u65b9\u4eba\u7fa4\u76f8\u6bd4\uff0c\u4e9a\u6d32\u4eba\u4e2d\u66f4\u6613\u51fa\u73b0\u66f4\u4e3a\u4e25\u91cd\u7684\u9057\u4f20\u6027\u8840\u6813\u503e\u5411\uff08\u4f8b\u5982\u6297\u51dd\u8840\u9176 (AT) \u7f3a\u4e4f\u3001\u86cb\u767d C (PC) \u7f3a\u4e4f\u548c\u86cb\u767d S (PS) \u7f3a\u4e4f\uff09\u3002 \u5176\u4e2d\uff0cAT \u7f3a\u4e4f\u6700\u4e3a\u4e25\u91cd\uff0c\u53ef\u4f7f VTE \u98ce\u9669\u589e\u52a0 50 \u500d\uff1b\u800c PC \u548c PS \u7f3a\u4e4f\u5219\u53ef\u4f7f\u98ce\u9669\u589e\u52a0 10 \u81f3 15 \u500d\u3002\u6211\u4eec\u7684\u5de5\u4f5c\u7ec4\u4e00\u81f4\u8ba4\u4e3a\uff0c\u6297\u51dd\u8840\u9176\u7f3a\u4e4f\u5e94\u8d4b\u4e88 4 \u5206\u7684\u98ce\u9669\u8bc4\u5206\uff0c\u4e00\u65e6\u786e\u8bca\u598a\u5a20\uff0c\u4ec5\u51ed\u8fd9\u4e00\u5371\u9669\u56e0\u7d20\u4fbf\u8db3\u4ee5\u542f\u52a8\u8840\u6813\u9884\u9632\u3002<\/p>\n

\u5bf9\u4e8e\u5177\u6709\u86cb\u767d S \u6216\u86cb\u767d C \u7f3a\u4e4f\u5e76\u4f34\u6709\u5176\u4ed6 VTE \u5371\u9669\u56e0\u7d20\uff08\u5982 VTE \u5bb6\u65cf\u53f2\uff09\u7684\u60a3\u8005\uff0c\u5e94\u8003\u8651\u7ed9\u4e88\u4ea7\u524d\u53ca\u4ea7\u540e\u8840\u6813\u9884\u9632\u6cbb\u7597\uff08\u4ea7\u540e\u9884\u9632\u6cbb\u7597\u53ef\u6301\u7eed\u81f3\u5206\u5a29\u540e 6 \u5468\uff09\u3002\u9700\u8981\u66f4\u591a\u7684\u4e9a\u6d32\u6570\u636e\u6765\u786e\u5b9a\u6b64\u7c7b\u8840\u6813\u503e\u5411\u7684\u4e34\u5e8a\u610f\u4e49\u548c\u98ce\u9669\u5206\u5c42\u3002<\/p>\n

\u9274\u4e8e\u73b0\u6709\u6587\u732e\u4e2d\u5173\u4e8e\u5e74\u9f84\u4f5c\u4e3a\u8840\u6813\u98ce\u9669\u56e0\u7d20\u7684\u6570\u636e\u5b58\u5728\u77db\u76fe\uff0c\u6211\u4eec\u56de\u987e\u5206\u6790\u4e86\u672c\u5730\u4e24\u5bb6\u4e09\u7ea7\u5987\u4ea7\u533b\u9662\uff08KKH \u548c SGH\uff09\u5728 2004 \u81f3 2016 \u5e74\u95f4\u5f00\u5c55\u7684\u4e00\u9879\u7814\u7a76\uff0c\u5171\u7eb3\u5165 89 \u4f8b\u4e0e\u598a\u5a20\u76f8\u5173 VTE \u5973\u6027\u548c 926 \u4f8b\u5bf9\u7167\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u5e74\u9f84 \u2265 35 \u5c81\u5e76\u975e VTE \u7684\u7edf\u8ba1\u5b66\u663e\u8457\u5371\u9669\u56e0\u7d20\u3002\u97e9\u56fd\u7684\u4e00\u9879\u7814\u7a76\u540c\u6837\u53d1\u73b0\uff0c\u5e74\u9f84\u589e\u52a0\u4e0e\u5b55\u671f VTE \u4e0d\u76f8\u5173\u3002\u7136\u800c\uff0c\u4e00\u9879\u82f1\u56fd\u57fa\u4e8e\u4eba\u7fa4\u7684\u5927\u578b\u961f\u5217\u7814\u7a76\u53d1\u73b0\uff0c\u5728\u975e\u598a\u5a20\u671f\uff0c\u6700\u9ad8\u5e74\u9f84\u7ec4\u5973\u6027\uff0835 \u81f3 44 \u5c81\uff09\u7684 VTE \u53d1\u751f\u7387\u6bd4 25 \u81f3 34 \u5c81\u5973\u6027\u9ad8 50%\u3002\u8fd9\u9879\u7814\u7a76\u8fd8\u53d1\u73b0\uff0c\u867d\u7136\u5728\u598a\u5a20\u671f VTE \u53d1\u751f\u7387\u5e76\u4e0d\u968f\u5e74\u9f84\u589e\u957f\u800c\u4e0a\u5347\uff0c\u4f46\u5728\u4ea7\u540e\u671f\uff0c35 \u5c81\u53ca\u4ee5\u4e0a\u5973\u6027\u7684 VTE \u98ce\u9669\u8f83 25 \u81f3 34 \u5c81\u5973\u6027\u9ad8\u51fa 70%\u3002\u57fa\u4e8e\u73b0\u6709\u8bc1\u636e\uff0c\u59d4\u5458\u4f1a\u56e0\u6b64\u51b3\u5b9a\u4ec5\u5728\u4ea7\u540e\u671f\u7684\u8840\u6813\u98ce\u9669\u8bc4\u4f30\u4e2d\u5c06\u5e74\u9f84\u7eb3\u5165\u5371\u9669\u56e0\u7d20\u3002\u226535 \u5c81\u9ad8\u9f84\u4ea7\u5987\u8fd9\u4e00\u8840\u6813\u5371\u9669\u56e0\u7d20\uff0c\u4ec5\u88ab\u7eb3\u5165\u4ea7\u540e\u8840\u6813\u9884\u9632\u8bc4\u4f30\u7684\u4e00\u90e8\u5206\u3002<\/p>\n

\u5728\u786e\u8bca\u65b0\u53d1 VTE \u7684\u6cbb\u7597\u4e2d\uff0c\u6297\u51dd\u6cbb\u7597\u662f\u6cbb\u7597\u7684\u57fa\u77f3\u3002\u5982\u679c\u4e0d\u4e88\u4ee5\u6cbb\u7597\uff0c\u7ea6 25% \u7684\u6df1\u9759\u8109\u8840\u6813\u5f62\u6210 (DVT) \u53ef\u8fdb\u5c55\u4e3a\u5177\u6709\u4e34\u5e8a\u610f\u4e49\u7684 PE\uff1b\u800c\u5728\u672a\u4e88\u4ee5\u9002\u5f53\u6cbb\u7597\u7684 VTE \u60a3\u8005\u4e2d\uff0cVTE \u590d\u53d1\u98ce\u9669\u53ef\u589e\u52a0 10 \u81f3 15 \u500d\u3002\u5145\u5206\u7684\u6cbb\u7597\u5242\u91cf\u548c\u5408\u9002\u7597\u7a0b\u7684\u6297\u51dd\u6cbb\u7597\uff0c\u5176\u91cd\u8981\u6027\u975e\u5e38\u91cd\u8981\u3002\u5728\u6297\u51dd\u836f\u7269\u7684\u9009\u62e9\u4e2d\uff0c\u65e2\u8981\u8003\u8651\u6bcd\u4f53\u548c\u80ce\u513f\u7684\u5e76\u53d1\u75c7\u98ce\u9669\uff0c\u4e5f\u8981\u517c\u987e\u5b55\u5987\u672c\u4eba\u7684\u610f\u613f\u3002\u5bf9\u4e8e\u6bcd\u4f53\u800c\u8a00\uff0c\u6cbb\u7597\u4e0d\u8db3\u53ef\u5bfc\u81f4\u8840\u6813\u5e76\u53d1\u75c7\uff0c\u800c\u8fc7\u5ea6\u6297\u51dd\u5219\u53ef\u5f15\u8d77\u51fa\u8840\u5e76\u53d1\u75c7\u3002\u5982\u679c\u6297\u51dd\u836f\u7269\u7a7f\u8fc7\u80ce\u76d8\uff0c\u53ef\u80fd\u4ea7\u751f\u81f4\u7578\u6027\uff0c\u5e76\u5bfc\u81f4\u80ce\u513f\u51fa\u8840\u5e76\u53d1\u75c7\u3002<\/p>\n

\u4f4e\u5206\u5b50\u91cf\u809d\u7d20 (LMWH) \u662f\u6cbb\u7597\u5b55\u671f VTE \u7684\u9996\u9009\u6297\u51dd\u836f\u7269\u3002\u8fd9\u662f\u7531\u4e8e\u5176\u7ed9\u836f\u65b9\u4fbf\uff0c\u4e0e\u666e\u901a\u672a\u5206\u7ea7\u809d\u7d20 (UFH) \u76f8\u6bd4\uff0c\u9aa8\u8d28\u758f\u677e\u548c\u51fa\u8840\u7684\u53d1\u751f\u7387\u66f4\u4f4e\uff0c\u4e14\u809d\u7d20\u8bf1\u5bfc\u7684\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u98ce\u9669\u4e5f\u8f83\u4f4e\u3002UFH \u548c LMWH \u5747\u4e0d\u4f1a\u7a7f\u8fc7\u80ce\u76d8\uff0c\u56e0\u6b64\u4e0d\u4f1a\u589e\u52a0\u80ce\u513f\u81f4\u7578\u6216\u51fa\u8840\u7684\u98ce\u9669\u3002\u5e94\u907f\u514d\u4f7f\u7528\u7ef4\u751f\u7d20 K \u62ee\u6297\u5242\uff0c\u56e0\u4e3a\u5176\u53ef\u7a7f\u8fc7\u80ce\u76d8\u5e76\u5bfc\u81f4\u534e\u6cd5\u6797\u80da\u80ce\u75c5\uff08\u4e2d\u9762\u90e8\u548c\u80a2\u4f53\u53d1\u80b2\u4e0d\u5168\u548c\u70b9\u72b6\u9aa8\u9aba\uff09\u3002\u534e\u6cd5\u6797\u8fd8\u4e0e\u598a\u5a20\u4e22\u5931\u4ee5\u53ca\u80ce\u513f\u6297\u51dd\u72b6\u6001\u548c\u51fa\u8840\u76f8\u5173\u3002\u56e0\u6b64\uff0c\u9664\u975e\u5728\u7279\u6b8a\u60c5\u51b5\u4e0b\uff0c\u6211\u4eec\u5efa\u8bae\u907f\u514d\u4f7f\u7528\u534e\u6cd5\u6797\u3002\u4e0d\u5efa\u8bae\u76f4\u63a5\u53e3\u670d\u6297\u51dd\u5242 (DOAC)\uff0c\u4f8b\u5982\u8fbe\u6bd4\u52a0\u7fa4\u3001\u963f\u54cc\u6c99\u73ed\u3001\u4f9d\u5ea6\u6c99\u73ed\u548c\u5229\u4f10\u6c99\u73ed\uff0c\u56e0\u4e3a\u5b83\u4eec\u53ef\u4ee5\u7a7f\u8fc7\u80ce\u76d8\u3002\u66fe\u6709\u6d41\u4ea7\u548c\u80ce\u513f\u7578\u5f62\u53d1\u751f\u7387\u589e\u52a0\u7684\u62a5\u544a\uff0c\u4e14\u7f3a\u4e4f\u598a\u5a20\u671f\u76f8\u5173\u7684\u5b89\u5168\u6027\u6570\u636e\u3002<\/p>\n

\u5728\u6574\u4e2a\u598a\u5a20\u671f\u95f4\u5e94\u7ef4\u6301\u6cbb\u7597\u5242\u91cf\u7684\u6297\u51dd\u6cbb\u7597\uff0c\u5e76\u81f3\u5c11\u6301\u7eed\u81f3\u4ea7\u540e 6 \u5468\uff0c\u4e14\u603b\u7597\u7a0b\u4e0d\u5c11\u4e8e 3 \u4e2a\u6708\u3002\u5982\u679c\u5728\u5b8c\u6210\u8db3\u591f\u7597\u7a0b\u7684\u6cbb\u7597\u5242\u91cf\u6297\u51dd\u6cbb\u7597\u540e\u60a3\u8005\u4ecd\u5904\u4e8e\u598a\u5a20\u671f\uff0c\u5219\u53ef\u4ee5\u5c06\u5242\u91cf\u4e0b\u8c03\u4e3a\u9884\u9632\u5242\u91cf\u3002\u5728\u505c\u6b62\u6297\u51dd\u6cbb\u7597\u4e4b\u524d\uff0c\u5e94\u518d\u6b21\u5bf9\u60a3\u8005\u8fdb\u884c VTE \u98ce\u9669\u8bc4\u5206\u3002<\/p>\n

\u5206\u5a29\u786c\u819c\u5916\u9ebb\u9189\u65f6\uff0c\u5e94\u7279\u522b\u5173\u6ce8\u7ed9\u836f\u7684\u65f6\u95f4\u5b89\u6392\u3002\u4e0e\u60a3\u8005\u8ba8\u8bba\u540e\uff0c\u53ef\u6839\u636e\u4e2a\u4f53\u60c5\u51b5\u505a\u51fa\u51b3\u7b56\u3002\u5982\u679c PTT \u6b63\u5e38\uff0c\u4e14\u5728\u786c\u819c\u5916\u7a7f\u523a\u524d 4 \u81f3 6 \u5c0f\u65f6\u5185\u672a\u4f7f\u7528\u666e\u901a\u809d\u7d20\uff0c\u5219\u53ef\u5b89\u5168\u8fdb\u884c\u3002\u5bf9\u4e8e\u63a5\u53d7 LMWH \u6cbb\u7597\u7684\u60a3\u8005\uff0c\u786c\u819c\u5916\u9ebb\u9189\u5e94\u5206\u522b\u5728\u8ddd\u6700\u540e\u4e00\u6b21\u9884\u9632\u5242\u91cf LMWH \u6ce8\u5c04\u81f3\u5c11 12 \u5c0f\u65f6\uff0c\u6216\u8ddd\u6700\u540e\u4e00\u6b21\u6cbb\u7597\u5242\u91cf LMWH \u6ce8\u5c04\u81f3\u5c11 24 \u5c0f\u65f6\u540e\u624d\u5b9e\u65bd\u3002<\/p>\n

\u6297\u51dd\u6cbb\u7597\u548c\u5206\u5a29\u65b9\u6848\u5e94\u7531\u4ea7\u79d1\u533b\u751f\u8054\u5408\u9ebb\u9189\u79d1\u533b\u751f\u53ca\u8840\u6db2\u79d1\u533b\u751f\u6216\u5185\u79d1\u533b\u751f\u5171\u540c\u5236\u5b9a\u3002\u5256\u5bab\u4ea7\u5e94\u4ec5\u57fa\u4e8e\u4ea7\u79d1\u6307\u5f81\u5b9e\u65bd\uff0c\u5e76\u5236\u5b9a\u76f8\u5e94\u7684\u6297\u51dd\u6cbb\u7597\u65b9\u6848\u4ee5\u914d\u5408\u6240\u9009\u5206\u5a29\u65b9\u5f0f\u3002<\/p>\n

\u5bf9\u4e8e\u63a5\u53d7\u6cbb\u7597\u5242\u91cf\u6297\u51dd\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u5728\u63d0\u524d\u505c\u7528\u6297\u51dd\u836f\u7269\u7684\u524d\u63d0\u4e0b\u5b89\u6392\u8ba1\u5212\u6027\u5206\u5a29\uff0c\u6b64\u4e3e\u6709\u52a9\u4e8e\u5b9e\u65bd\u786c\u819c\u5916\u9ebb\u9189\uff0c\u5e76\u964d\u4f4e\u4ea7\u5987\u51fa\u8840\u98ce\u9669\u3002\u5bf9\u4e8e\u63a5\u53d7\u9884\u9632\u5242\u91cf LMWH \u7684\u60a3\u8005\uff0c\u53ef\u4ee5\u8003\u8651\u5141\u8bb8\u5176\u81ea\u53d1\u5206\u5a29\uff0c\u5e76\u5728\u4e34\u4ea7\u65f6\u505c\u7528\u6297\u51dd\u836f\u7269\u3002\u53ea\u8981\u6807\u51c6\u9884\u9632\u5242\u91cf LMWH \u6700\u540e\u4e00\u5242\u4e0e\u786c\u819c\u5916\u5bfc\u7ba1\u7f6e\u5165\u4e4b\u95f4\u7684\u95f4\u9694\u226512 \u5c0f\u65f6\uff0c\u5927\u591a\u6570\u4ea7\u5987\u5728\u8ba1\u5212\u5206\u5a29\u6216\u81ea\u53d1\u5206\u5a29\u65f6\u90fd\u53ef\u4ee5\u63a5\u53d7\u786c\u819c\u5916\u9ebb\u9189\u3002<\/p>\n

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\u53c2\u8003\u6587\u732e\uff1a<\/em><\/p>\n

[1]<\/a> Oral contraceptives and hormone replacement therapy: How strong a risk factor for venous thromboembolism?\u00a0Leslie Skeith a,, Gr\u00b4egoire Le Gal , Marc A.Rodger.Thrombosis Research 202 (2021) 134\u2013138<\/p>\n

[2]<\/a> Reducing the Risk of Venous Thromboembolism during Pregnancy and the Puerperium RCOG Green-top Guideline No. 37a, 2015<\/p>\n

[3]<\/a> CONSENSUS STATEMENT on VENOUS THROMBOEMBOLISM IN PREGNANCY \u2013 RECOMMENDATIONS FOR PREVENTION, TREATMENT AND INVESTIGATION.College of Obstetricians and Gynaecologists (COGS), Chapter of Haematologists, College of Physicians, Singapore.<\/p>\n","protected":false},"excerpt":{"rendered":"

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