{"id":141344,"date":"2023-05-26T03:04:59","date_gmt":"2023-05-26T03:04:59","guid":{"rendered":"https:\/\/labinsights.com\/acf_article\/%e8%88%87%e8%8d%b7%e7%88%be%e8%92%99%e7%99%82%e6%b3%95%e5%8f%8a%e8%88%87%e8%b3%80%e7%88%be%e8%92%99%e7%99%82%e6%b3%95%e4%bd%b6%e5%a6%8a%e5%a8%a0%e7%9b%b8%e9%97%9c%e7%9a%84vte%ef%bc%9a%e8%88%87lai-heng\/"},"modified":"2026-01-19T07:34:50","modified_gmt":"2026-01-19T07:34:50","slug":"vte-associated-with-hormone-therapy-and-pregnancy-assoc-prof-lai-heng-lee-on-risk-and-management","status":"publish","type":"acf_article","link":"https:\/\/labinsights.com\/zhtw\/disease-area\/womens-health\/vte-associated-with-hormone-therapy-and-pregnancy-assoc-prof-lai-heng-lee-on-risk-and-management\/","title":{"rendered":"\u8207\u8377\u723e\u8499\u7642\u6cd5\u53ca\u8207\u8cc0\u723e\u8499\u7642\u6cd5\u4f76\u598a\u5a20\u76f8\u95dc\u7684VTE\uff1a\u8207Lai Heng Lee\u6559\u6388\u6709\u95dc\u98a8\u96aa\u8207\u7ba1\u7406"},"content":{"rendered":"

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\u7136\u800c\uff0c\u518d\u6b21\u5f37\u8abf\uff0c\u77ad\u89e3\u7d55\u5c0d\u98a8\u96aa\u6709\u52a9\u65bc\u5728\u8aee\u8a62\u5177\u6709\u5df2\u77e5\u8840\u6813\u6027\u60a3\u8005\u500b\u4eba\u6216\u5bb6\u65cf\u75c5\u53f2\u7684\u60a3\u8005\u6642\u6b63\u8996\u554f\u984c\u3002\u60a3\u6709FVL\u6216PGM\u7684COC\u5973\u6027\u4e2dVTE\u7684\u7d55\u5c0d\u98a8\u96aa\u7bc4\u570d\u70ba\u6bcf100\u4e38\u5e740.45\u81f32\uff0c\u4e26\u4e14\u8207\u61f7\u5b55\u98a8\u96aa\u76f8\u6bd4\uff0c\u9019\u4e9bVTE\u98a8\u96aa\u5c0d\u65bc\u4e00\u4e9b\u5973\u6027\u800c\u8a00\u53ef\u80fd\u66f4\u5bb9\u6613\u63a5\u53d7\u3002\u7136\u800c\uff0c\u5728\u7f3a\u4e4f\u6709\u529b\u8cc7\u6599\u7684\u66f4\u6709\u6548\u7684\u8840\u6813\u6027\u50be\u5411\u75c5\u4e2d\uff0c\u64da\u5831\u5c0e\u7d55\u5c0d\u98a8\u96aa\u70ba\u6bcf100\u4e38\u5e744.3\u81f34.5\u6b21\uff0c\u4e26\u5efa\u8b70\u66f4\u8b39\u614e\u4e14\u4f7f\u7528\u66ff\u4ee3\u907f\u5b55\u65b9\u6cd5\u3002<\/p>\n

\u5373\u4f7f\u5982\u6b64\uff0c\u4e0d\u5efa\u8b70\u5728\u4f7f\u7528COC\u4e4b\u524d\u9032\u884c\u4e0d\u5408\u7406\u7684\u5e38\u898f\u8840\u6813\u50be\u5411\u5927\u91cf\u7be9\u67e5\u3002\u6b64\u985e\u7be9\u9078\u4e0d\u5177\u6709\u6210\u672c\u6548\u76ca\uff0c\u56e0\u70ba\u5927\u91cf\u5973\u6027\u9700\u8981\u63a5\u53d7\u6e2c\u8a66\u4e26\u5efa\u8b70\u5176\u6212\u9664COC\u4f7f\u7528\uff0c\u4ee5\u9632\u6b621\u4f8b\u55ae\u4e00\u8840\u6813\u4e8b\u4ef6\u3002\u6b64\u5916\uff0c\u5c0d\u65bc\u8f03\u8f15\u7684\u8840\u6813\u6027\u50be\u5411\uff0cVTE\u7684\u7d55\u5c0d\u98a8\u96aa\u5f88\u5c0f\uff0c\u4e26\u4e14\u5927\u591a\u6578VTE\u4e8b\u4ef6\u767c\u751f\u5728\u672a\u9451\u5b9a\u51fa\u907a\u50b3\u6027\u8840\u6813\u50be\u5411\u7684\u5973\u6027\u4e2d\u3002\u7136\u800c\uff0c\u5728\u6295\u4e88COC\u4e4b\u524d\u4e4b\u9078\u64c7\u6027\u6e2c\u8a66\u53ef\u7528\u65bc\u6cbb\u7642\u8207\u8840\u6813\u50be\u5411\u5f62\u6210\u98a8\u96aa\u5927\u5927\u589e\u52a0\u76f8\u95dc\u7684\u56b4\u91cd\u8840\u6813\u6027\u6613\u611f\u6027\u4e4b\u651c\u5e36\u8005\u7684\u7121\u75c7\u72c0\u89aa\u5c6c\uff0c\u8af8\u5982\u6297\u51dd\u8840\u9176\u3001PC\u53caPS\u7f3a\u4e4f\u4ee5\u53caFV Leiden\u53caFII G20210A\u4e4b\u7d14\u5408\u6027\u3002<\/p>\n

\u598a\u5a20\u76f8\u95dc\u7684\u975c\u8108\u8840\u6813\u6813\u585e<\/h2>\n

\u598a\u5a20\u53ca\u5176\u751f\u7406\u8b8a\u5316\u5c0e\u81f4\u51dd\u8840\u56e0\u5b50\uff08VII\u3001VIII\u3001X\u53ca\u8840\u7ba1\u6027\u8840\u53cb\u75c5\u56e0\u5b50\uff09\u542b\u91cf\u589e\u52a0\uff0c\u540c\u6642\u5929\u7136\u6297\u51dd\u5291(PS)\u6e1b\u5c11\u3002\u9019\u7a2e\u9ad8\u51dd\u72c0\u614b\u8207\u4e0b\u80a2\u5c0d\u975c\u8108\u6de4\u6eef\u72c0\u614b\u4ee5\u53ca\u5c0d\u9aa8\u76c6\u8840\u7ba1\u7684\u5167\u76ae\u640d\u50b7\u4e00\u8d77\uff0c\u6eff\u8db3\u4e86Virchow\u7684\u8840\u6813\u5f62\u6210\u56e0\u5b50\u4e09\u806f\u7642\u6cd5\uff0c\u9019\u4e9b\u56e0\u5b50\u662f\u7570\u5e38\u975c\u8108\u51dd\u584a\u767c\u75c5\u6a5f\u5236\u7684\u57fa\u790e\uff0c\u6613\u60a3VTE\u3002<\/p>\n

\u598a\u5a20\u671fVTE\u7684\u98a8\u96aa\u7d04\u70ba1\/1,000\u4f8b\u598a\u5a20\uff0c\u7522\u524d\u548c\u7522\u5f8c\u671fVTE\u7684\u767c\u751f\u7387\u76f8\u4f3c\u3002\u7531\u65bc\u7522\u5f8c\u6642\u9593\u6bd4\u7522\u524d\u6642\u9593\u77ed\uff0c\u56e0\u6b64\u6bcf\u65e5VTE\u98a8\u96aa\u66f4\u9ad8\uff0c\u4e26\u4e14\u9019\u7a2e\u589e\u52a0\u7684\u98a8\u96aa\u6301\u7e8c\u5230\u7522\u5f8c12\u9031\uff0c\u5728\u5206\u5a29\u5f8c\u7684\u524d6\u9031\u5167\u98a8\u96aa\u6700\u5927\u3002<\/p>\n

\u5982\u679c\u4e0d\u6cbb\u7642\uff0c\u80ba\u6813\u585e(PE)\u572825%\u7684\u60a3\u8005\u4e2d\u662f\u81f4\u547d\u7684\u3002\u56e0\u6b64\uff0cVTE\u662f\u5c0e\u81f4\u7522\u5a66\u767c\u751f\u7387\u53ca\u6b7b\u4ea1\u7387\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u5728\u897f\u65b9\u4eba\u7fa4\u4e2d\u4f54\u7522\u5a66\u6b7b\u4ea1\u768417%\u3002\u77ad\u89e3\u4e26\u5206\u5c64\u598a\u5a20\u767c\u751fVTE\u7684\u98a8\u96aa\u56e0\u7d20\u975e\u5e38\u91cd\u8981\uff0c\u4ee5\u4fbf\u53ef\u4ee5\u61c9\u7528\u9069\u7576\u7684\u8840\u6813\u9810\u9632\u63aa\u65bd\u3002<\/p>\n

\u6709\u8a31\u591a\u95dc\u65bc\u598a\u5a20\u76f8\u95dcVTE\u7684VTE\u98a8\u96aa\u5206\u5c64\u53ca\u7ba1\u7406\u7684\u6307\u5357\uff0c\u4e3b\u8981\u57fa\u65bc\u5f9e\u975e\u598a\u5a20\u60a3\u8005\u53ca\u897f\u65b9\u4eba\u7fa4\u4e2d\u598a\u5a20\u60a3\u8005\u7684\u75c5\u4f8b\u7cfb\u5217\u5206\u6790\u5916\u63a8\u7684\u8cc7\u6599\u3002\u00a0\u6839\u64da\u672c\u5730\u8cc7\u6599\u5236\u5b9a\u672c\u5730\u6307\u5357\u975e\u5e38\u91cd\u8981\u3002\u5728\u65b0\u52a0\u5761\uff0c\u91ab\u5e2b\u548c\u5a66\u7522\u79d1\u91ab\u5e2b\u5b78\u9662\u7684\u5206\u6703\u5171\u540c\u5be9\u67e5\u9019\u4e9b\u6307\u5357\u548c\u53ef\u7528\u7684\u672c\u5730\u8cc7\u6599\uff0c\u4ee5\u5236\u5b9a\u7ba1\u7406\u598a\u5a20\u76f8\u95dcVTE\u7684\u5171\u8b58\u5efa\u8b70\u3002VTE\u98a8\u96aa\u5206\u5c64\u662f\u63a1\u7d0d\u81ea\u82f1\u570b\u7687\u5bb6\u5a66\u7522\u79d1\u91ab\u5e2b\u5b78\u6703(Royal College of Obstetricians and Gynecologist\uff0cUK) Greentop Guideline 37a\uff0c\u4e26\u6839\u64da\u6211\u5011\u5728\u5730\u7684\u8cc7\u6599\u548c\u81e8\u5e8a\u91ab\u5e2b\u7684\u610f\u898b\u9032\u884c\u8abf\u6574\u3002<\/p>\n

\u6307\u5357\u4e2d\u5305\u62ec\u7684\u767c\u751fVTE\u7684\u5371\u96aa\u56e0\u7d20\u57fa\u65bc\u5148\u524dVTE\u7684\u75c5\u53f2\u3001\u907a\u50b3\u6027\u8840\u6813\u50be\u5411\u3001\u60a3\u8005\u73fe\u6709\u7684\u5371\u96aa\u56e0\u7d20\u3001\u7522\u79d1\u5371\u96aa\u56e0\u7d20\u53ca\u5176\u4ed6\u77ed\u66ab\u7684\u5371\u96aa\u56e0\u7d20\u3002\u6839\u64da\u5404\u98a8\u96aa\u56e0\u7d20\u4e4b\u8840\u6813\u5f62\u6210\u98a8\u96aa\u6b0a\u91cd\u78ba\u5b9a\u5404\u98a8\u96aa\u56e0\u7d20\u4e4b\u5206\u6578\u3002\u8840\u6813\u9810\u9632\u7684\u5efa\u8b70\u57fa\u65bc\u5206\u6578\u6216\u98a8\u96aa\u5206\u6578\u3002\u56e0\u6b64\uff0c\u4e00\u65e6\u8a3a\u65b7\u51fa\u598a\u5a20\uff0c\u7522\u524d\u8840\u6813\u9810\u9632\u5c07\u8003\u616e\u7e3d\u8a55\u5206\u70ba4\u53ca\u4ee5\u4e0a\uff0c\u800c\u5f9e\u598a\u5a2028\u9031\u958b\u59cb\uff0c\u5177\u67093\u5206\u7684\u60a3\u8005\u5c07\u8003\u616e\u8840\u6813\u9810\u9632\uff1b\u7522\u5f8c\u8840\u6813\u9810\u9632\u7b56\u7565\u4ea6\u57fa\u65bc\u8a55\u5206\u77e9\u9663\u3002<\/p>\n

\u7531\u65bcVTE\u7684\u98a8\u96aa\u662f\u52d5\u614b\u7684\uff0c\u4e26\u4e14\u96a8\u8457\u598a\u5a20\u9032\u5c55\u96a8\u8457\u65b0\u98a8\u96aa\u56e0\u7d20\u7684\u51fa\u73fe\u6216\u5148\u524d\u98a8\u96aa\u56e0\u7d20\u7684\u6d88\u9000\u800c\u8b8a\u5316\uff0c\u56e0\u6b64\u5728\u6574\u500b\u598a\u5a20\u548c\u7522\u8925\u671f\u7684\u4e0d\u540c\u6642\u9593\u9ede\u91cd\u8907\u8a55\u4f30VTE\u98a8\u96aa\u975e\u5e38\u91cd\u8981\u3002\u8a55\u4f30\u51fa\u8840\u98a8\u96aa\u4e5f\u5f88\u91cd\u8981\u3002\u5982\u679c\u60a3\u8005\u4e0d\u9069\u5408\u6297\u51dd\u9810\u9632\uff0c\u5247\u53ef\u4ee5\u8003\u616e\u4f7f\u7528\u58d3\u7e2e\u88dd\u7f6e\u6216\u896a\u5b50\u9032\u884c\u6a5f\u68b0\u9810\u9632\u3002<\/p>\n

\u65b0\u52a0\u5761\u5171\u8b58\u5efa\u8b70\u4e2d\u4f5c\u51fa\u7684\u8abf\u6574\u70ba\u907a\u50b3\u6027\u8840\u6813\u50be\u5411\u53ca\u6bcd\u89aa\u5e74\u9f61\u589e\u52a0\u7684\u52a0\u6b0a\u9ede\u3002\u8207\u897f\u65b9\u4eba\u7fa4\u76f8\u6bd4\uff0c\u66f4\u56b4\u91cd\u5f62\u5f0f\u7684\u907a\u50b3\u6027\u8840\u6813\u50be\u5411\u8af8\u5982\u6297\u51dd\u8840\u9176(AT)\u3001PC\u53caPS\u7f3a\u4e4f\u75c7\u5728\u4e9e\u6d32\u66f4\u70ba\u666e\u904d\uff08AT\u7f3a\u4e4f\u662f\u6700\u56b4\u91cd\u7684\uff0c\u8207VTE\u98a8\u96aa\u589e\u52a050\u500d\u76f8\u95dc\uff0c\u800cPC\u53caPS def\u5c07\u98a8\u96aa\u589e\u52a010-15\u500d\uff09\u3002\u6211\u5011\u7684\u5de5\u4f5c\u7d44\u4e00\u81f4\u8a8d\u70ba\uff0c\u6297\u51dd\u8840\u9176\u7f3a\u4e4f\u75c7\u7684\u98a8\u96aa\u5206\u6578\u61c9\u70ba4\uff0c\u4e14\u4e00\u65e6\u8a3a\u65b7\u51fa\u61f7\u5b55\uff0c\u50c5\u6191\u9019\u4e00\u98a8\u96aa\u56e0\u7d20\u5373\u53ef\u8b49\u660e\u958b\u59cb\u8840\u6813\u9810\u9632\u7684\u5408\u7406\u6027\u3002<\/p>\n

\u5177\u6709\u86cb\u767dS\u6216\u86cb\u767dC\u7f3a\u4e4f\u4ee5\u53ca\u5176\u4ed6VTE\u98a8\u96aa\u56e0\u7d20\uff08\u8af8\u5982VTE\u5bb6\u65cf\u53f2\uff09\u7684\u60a3\u8005\u61c9\u8003\u616e\u9032\u884c\u7522\u524d\u53ca\u7522\u5f8c\u9810\u9632\uff08\u7522\u5f8c\u6700\u591a6\u9031\uff09\u3002\u9700\u8981\u66f4\u591a\u7684\u4e9e\u6d32\u8cc7\u6599\u4f86\u78ba\u5b9a\u9019\u4e9b\u8840\u6813\u5f62\u6210\u75c7\u7684\u81e8\u5e8a\u610f\u7fa9\u548c\u98a8\u96aa\u5206\u5c64\u3002<\/p>\n

\u7531\u65bc\u7576\u524d\u6587\u737b\u4e2d\u6709\u95dc\u5e74\u9f61\u4f5c\u70ba\u8840\u6813\u5f62\u6210\u98a8\u96aa\u56e0\u7d20\u7684\u8cc7\u6599\u76f8\u4e92\u77db\u76fe\uff0c\u6211\u5011\u56de\u9867\u4e86\u6700\u8fd1\u57282\u5bb6\u4e09\u7d1a\u5a66\u7522\u91ab\u9662\uff08KKH\u548cSGH\uff09\u9032\u884c\u7684\u5728\u5730\u7814\u7a76\uff0c\u6642\u9593\u8de8\u5ea6\u70ba2004\u5e74\u81f32016\u5e7412\u5e74\uff0c\u7814\u7a76\u5c0d\u8c61\u70ba89\u4f8b\u598a\u5a20\u76f8\u95dcVTE\u5973\u6027\u548c926\u4f8b\u5c0d\u7167\u3002\u7d50\u679c\u767c\u73fe\uff0c\u5e74\u9f61\u5927\u65bc\u6216\u7b49\u65bc35\u6b72\u4e0d\u662fVTE\u7684\u7d71\u8a08\u5b78\u986f\u8457\u98a8\u96aa\u56e0\u7d20\u3002\u4e00\u9805\u97d3\u570b\u7814\u7a76\u5f97\u51fa\u985e\u4f3c\u7d50\u679c\uff0c\u5e74\u9f61\u589e\u52a0\u8207\u598a\u5a20\u4e2d\u7684VTE\u7121\u95dc\u3002\u7136\u800c\uff0c\u82f1\u570b\u4e00\u9805\u5927\u578b\u57fa\u65bc\u4eba\u7fa4\u7684\u7fa4\u7d44\u7814\u7a76\u767c\u73fe\uff0c\u5728\u61f7\u5b55\u4e4b\u5916\uff0c\u5e74\u9f61\u6700\u5927\u7bc4\u570d\uff0835-44\u6b72\uff09\u7684\u5973\u6027\u7684VTE\u7387\u6bd425-34\u6b72\u7684\u5973\u6027\u9ad850%\u3002\u6b64\u7814\u7a76\u4ea6\u767c\u73fe\uff0c\u5118\u7ba1\u7522\u524d\u671fVTE\u7684\u6bd4\u7387\u4e0d\u96a8\u5e74\u9f61\u800c\u589e\u52a0\uff0c\u4f46\u8207\u7522\u5f8c25-34\u6b72\u4e4b\u5e74\u9f61\u7d44\u76f8\u6bd4\uff0c35\u6b72\u53ca\u4ee5\u4e0a\u4e4b\u5973\u6027\u7684\u98a8\u96aa\u589e\u52a070%\u3002\u57fa\u65bc\u73fe\u6709\u8b49\u64da\uff0c\u59d4\u54e1\u6703\u56e0\u6b64\u6c7a\u5b9a\u50c5\u5728\u7522\u5f8c\u8840\u6813\u98a8\u96aa\u8a55\u4f30\u4e2d\u4f7f\u7528\u5e74\u9f61\u4f5c\u70ba\u8840\u6813\u5f62\u6210\u7684\u98a8\u96aa\u56e0\u7d20\u3002\u8d85\u904e35\u6b72\u7684\u665a\u671f\u6bcd\u9ad4\u5e74\u9f61\u4f5c\u70ba\u8840\u6813\u5f62\u6210\u7684\u98a8\u96aa\u56e0\u7d20\u50c5\u4f5c\u70ba\u8840\u6813\u9810\u9632\u7684\u51fa\u751f\u5f8c\u8a55\u4f30\u7684\u4e00\u90e8\u5206\u88ab\u5305\u62ec\u5728\u5167\u3002<\/p>\n

\u5c0d\u65bc\u7d93\u78ba\u8a8d\u4e4b\u65b0VTE\u7684\u7ba1\u7406\uff0c\u6297\u51dd\u662f\u6cbb\u7642\u7684\u57fa\u77f3\u3002\u5982\u679c\u4e0d\u6cbb\u7642\uff0c25%\u7684\u6df1\u975c\u8108\u8840\u6813\u5f62\u6210(DVT)\u5c07\u767c\u5c55\u70ba\u81e8\u5e8a\u76f8\u95dc\u7684PE\uff0c\u4e26\u4e14\u6cbb\u7642\u4e0d\u7576\u7684VTE\u4e2d\u5fa9\u767c\u6027VTE\u589e\u52a010-15\u500d\u3002\u4e0d\u80fd\u904e\u5206\u5f37\u8abf\u8db3\u5920\u7684\u6cbb\u7642\u5291\u91cf\u53ca\u9069\u7576\u7684\u6297\u51dd\u6cbb\u7642\u6301\u7e8c\u6642\u9593\u7684\u91cd\u8981\u6027\u3002\u5728\u6297\u51dd\u8840\u85e5\u7269\u7684\u9078\u64c7\u4e2d\uff0c\u91cd\u8981\u7684\u662f\u8003\u616e\u6bcd\u9ad4\u53ca\u80ce\u5152\u4f75\u767c\u75c7\u4ee5\u53ca\u6bcd\u89aa\u7684\u504f\u597d\u3002\u5728\u6bcd\u89aa\u4e2d\uff0c\u5b58\u5728\u6cbb\u7642\u4e0d\u8db3\u7684\u8840\u6813\u4f75\u767c\u75c7\u53ca\u904e\u5ea6\u6297\u51dd\u7684\u51fa\u8840\u4f75\u767c\u75c7\u3002\u82e5\u6297\u51dd\u8840\u5291\u85e5\u7269\u7a7f\u904e\u80ce\u76e4\uff0c\u5247\u53ef\u80fd\u9020\u6210\u80ce\u5152\u7684\u81f4\u7578\u6027\u53ca\u51fa\u8840\u4f75\u767c\u75c7\u3002<\/p>\n

\u4f4e\u5206\u5b50\u91cf\u809d\u7d20(LMWH)\u662f\u6cbb\u7642\u598a\u5a20VTE\u7684\u9996\u9078\u6297\u51dd\u5291\u3002\u9019\u662f\u7531\u65bc\u6295\u4e88\u5bb9\u6613\uff0c\u8207\u666e\u901a\u809d\u7d20(UFH)\u76f8\u6bd4\uff0c\u9aa8\u8cea\u758f\u9b06\u75c7\u7684\u98a8\u96aa\u8f03\u4f4e\uff0c\u51fa\u8840\u7387\u964d\u4f4e\u4ee5\u53ca\u809d\u7d20\u8a98\u5c0e\u7684\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u7684\u98a8\u96aa\u8f03\u4f4e\u3002UFH\u548cLMWH\u5747\u672a\u7a7f\u904e\u80ce\u76e4\uff0c\u56e0\u6b64\u8207\u81f4\u7578\u80ce\u6027\u6216\u80ce\u5152\u51fa\u8840\u7684\u98a8\u96aa\u7121\u95dc\u3002\u7576\u7dad\u751f\u7d20K\u62ee\u6297\u5291\u7a7f\u904e\u80ce\u76e4\u4e26\u5f15\u8d77\u83ef\u6cd5\u6797\u80da\u80ce\u75c5\uff08\u9762\u4e2d\u6bb5\u53ca\u80a2\u9ad4\u767c\u80b2\u4e0d\u5168\u3001\u9ede\u72c0\u9aa8\u9aba\uff09\u6642\uff0c\u61c9\u907f\u514d\u4f7f\u7528\u3002\u00a0\u83ef\u6cd5\u6797\u4ea6\u8207\u598a\u5a20\u53ca\u80ce\u5152\u6297\u51dd\u8840\u53ca\u51fa\u8840\u7684\u640d\u5931\u6709\u95dc\u3002\u56e0\u6b64\uff0c\u9664\u975e\u5728\u7279\u6b8a\u60c5\u6cc1\u4e0b\uff0c\u5426\u5247\u6211\u5011\u5efa\u8b70\u907f\u514d\u4f7f\u7528\u83ef\u6cd5\u6797\u3002\u4e0d\u5efa\u8b70\u4f7f\u7528\u76f4\u8178\u9014\u5f91\u670d\u6297\u51dd\u5291(DOAC)\uff0c\u8af8\u5982\u9054\u6bd4\u52a0\u7fa4(dabigatran)\u3001\u963f\u54cc\u6c99\u73ed(apixaban)\u3001\u4f9d\u5ea6\u6c99\u73ed(edoxaban)\u53ca\u5229\u4f10\u6c99\u73ed(rivaroxaban)\uff0c\u56e0\u70ba\u5b83\u5011\u7a7f\u904e\u80ce\u76e4\u3002\u66fe\u6709\u6d41\u7522\u53ca\u80ce\u5152\u7570\u5e38\u589e\u52a0\u7684\u5831\u544a\uff0c\u4e14\u7f3a\u4e4f\u598a\u5a20\u7684\u5b89\u5168\u6027\u8cc7\u6599\u3002<\/p>\n

\u6297\u51dd\u5291\u61c9\u5728\u598a\u5a20\u671f\u9593\u7dad\u6301\u6cbb\u7642\u5291\u91cf\u7684\u6297\u51dd\u5291\uff0c\u6301\u7e8c\u81f3\u7522\u5f8c\u81f3\u5c116\u9031\uff0c\u4e26\u4e14\u7e3d\u5171\u6700\u5c113\u500b\u6708\u3002\u82e5\u60a3\u8005\u5728\u8db3\u5920\u9577\u6642\u9593\u7684\u6cbb\u7642\u6027\u6297\u51dd\u5f8c\u4ecd\u61f7\u5b55\uff0c\u5247\u5291\u91cf\u53ef\u6e1b\u5c11\u81f3\u9810\u9632\u6027\u5291\u91cf\u3002\u5728\u505c\u6b62\u6297\u51dd\u6cbb\u7642\u4e4b\u524d\uff0c\u60a3\u8005\u61c9\u63a5\u53d7\u53e6\u4e00\u6b21VTE\u98a8\u96aa\u8a55\u5206\u3002<\/p>\n

\u786c\u819c\u5916\u9ebb\u9189\u5c0e\u7ba1\u7d66\u85e5\uff0c\u53ef\u7279\u5225\u6ce8\u610f\u6295\u4e88\u6642\u9593\u3002\u8207\u60a3\u8005\u8a0e\u8ad6\u5f8c\uff0c\u53ef\u4ee5\u55ae\u7368\u505a\u51fa\u6c7a\u5b9a\u3002\u82e5PTT\u6b63\u5e38\u4e14\u5728\u786c\u819c\u5916\u5c0e\u7ba1\u63d2\u5165\u524d\u672a\u6295\u4e88\u6a19\u6e96\u809d\u7d204-6\u5c0f\u6642\uff0c\u5247\u4fc2\u5b89\u5168\u7684\u3002\u5c0d\u65bc\u63a5\u53d7LMWH\u7684\u60a3\u8005\uff0c\u786c\u819c\u5916\u9ebb\u9189\u53ef\u5728\u6700\u5f8c\u4e00\u6b21\u9810\u9632\u6027\u5291\u91cf\u5f8c\u81f3\u5c1112\u5c0f\u6642\u53ca\u6700\u5f8c\u4e00\u6b21\u6cbb\u7642\u5291\u91cfLMWH\u5f8c24\u5c0f\u6642\u6295\u4e88\u3002<\/p>\n

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\u85e5\u7269\u905e\u9001\u5f8c\uff0c\u4e0d\u61c9\u5728\u6700\u8fd1\u7684\u6cbb\u7642\u6027LMWH\u6ce8\u5c04\u5f8c24\u5c0f\u6642\u5167\u79fb\u9664\u786c\u819c\u5916\u5c0e\u7ba1\u3002\u5728\u4f7f\u7528\u810a\u9ad3\u9ebb\u9189\u5f8c\u81f3\u5c114\u5c0f\u6642\u6216\u786c\u819c\u5916\u5c0e\u7ba1\u79fb\u9664\u5f8c\uff0c\u624d\u61c9\u7d66\u4e88LMWH\u3002\u5982\u679c\u60a3\u8005\u4e0d\u5177\u6709\u9ad8\u51fa\u8840\u98a8\u96aa\uff0c\u4e14\u6b62\u8840\u5f97\u5230\u4fdd\u8b49\uff0c\u814e\u529f\u80fd\u6b63\u5e38\u4e14\u7121\u51dd\u8840\u75c5\u8b8a\u4ee5\u53ca\u5728\u786c\u819c\u5916\u9ebb\u9189\u5f8c\u5b8c\u5168\u795e\u7d93\u6062\u5fa9\uff0c\u5247\u53ef\u4ee5\u5728\u5206\u5a29\u5f8c4-6\u5c0f\u6642\u91cd\u65b0\u958b\u59cb\u9810\u9632\u6027\u5291\u91cfLMWH\uff0c\u4e26\u5728\u5206\u5a29\u5f8c24\u5c0f\u6642\u91cd\u65b0\u958b\u59cb\u6cbb\u7642\u6027LMWH\u3002\u7576\u6bcd\u89aa\u4f7f\u7528LMWH\u6216\u83ef\u6cd5\u6797\u6642\uff0c\u6bcd\u4e73\u9935\u990a\u5c0d\u5b30\u5152\u662f\u5b89\u5168\u7684\u3002\u4e0d\u5efa\u8b70\u54fa\u4e73\u6bcd\u89aa\u4f7f\u7528DOAC\uff0c\u56e0\u70ba\u5b83\u6703\u5206\u6ccc\u5230\u4e73\u6c41\u4e2d\uff0c\u4e14\u7f3a\u4e4f\u5b89\u5168\u6027\u8cc7\u6599\u3002<\/p>\n

\u53c3\u8003\u6587\u737b\uff1a<\/em><\/p>\n

[1]<\/a> \u53e3\u670d\u907f\u5b55\u85e5\u53ca\u6fc0\u7d20\u66ff\u4ee3\u7642\u6cd5\uff1a\u975c\u8108\u8840\u6813\u6813\u585e\u7684\u98a8\u96aa\u56e0\u7d20\u6709\u591a\u5f37\uff1f\u00a0Leslie Skeith a\uff0cGr\u00b4egoire Le Gal\uff0cMarc A.Rodger\u3002Thrombosis Research 202 (2021) 134-138<\/p>\n

[2]<\/a> \u964d\u4f4e\u61f7\u5b55\u671f\u9593\u975c\u8108\u8840\u6813\u6813\u585e\u7684\u98a8\u96aa\u53ca\u7522\u8925\u671fRCOG\u7da0\u9802\u6307\u5357\u7b2c37a\u865f\uff0c2015<\/p>\n

[3]<\/a> \u598a\u5a20\u975c\u8108\u8840\u6813\u6813\u585e\u5171\u8b58\u5ba3\u544a-\u9810\u9632\u3001\u6cbb\u7642\u53ca\u8abf\u67e5\u4e4b\u5efa\u8b70\u3002\u65b0\u52a0\u5761\u5a66\u7522\u79d1\u5b78\u9662\uff0c\u65b0\u52a0\u5761\u5167\u79d1\u91ab\u5e2b\u5b78\u9662\u8840\u6db2\u79d1\u91ab\u5e2b\u5206\u6703\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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