Sepsis

The role of biomarkers in management of sepsis

The role of biomarkers in management of sepsis

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defines sepsis as a ‘life-threatening organ dysfunction caused by a dysregulated host response to infection’. Septic shock is defined as ‘a subset of sepsis in which the underlying circulatory, cellular and metabolic abnormalities are associated with a greater risk of mortality than sepsis alone’. […]

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Sepsis care gaps in Asia demonstrate need for better diagnostics

Sepsis care gaps in Asia demonstrate need for better diagnostics

September 13th marks World Sepsis Day, a global event designed to help raise awareness of a dangerous and often deadly condition. In the Asia Pacific region, the need for better sepsis care—including high-quality diagnostics to help identify and manage the condition—is particularly urgent. Globally, as many as 50 million people suffer from sepsis every year,

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Harnessing lactate POC values to deliver early sepsis diagnosis

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Sepsis is a global killer. About 27 million people around the world develop sepsis every year, and some eight million people die from it, according to a November 2018 article in The Lancet [1]. This leaves 19 million people living with the long-term consequences of the infection. In Thailand alone, this translates to 175,000 infections with sepsis

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Antimicrobial resistance and the role of procalcitonin (PCT)

Antimicrobial Resistance and the role of Procalcitonin (PCT)

Procalcitonin (PCT) plays a central role for successful antimicrobial stewardship programs. Originally considered a “sepsis biomarker”, PCT has evolved to aid in the de-escalation of antimicrobial therapy and help differentiate between bacterial versus non-bacterial infections. The University of California (UC), Davis Health system implemented PCT in late-2014. Procalcitonin was found in our studies to correlate with sepsis

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